LOCUS       XM_017354872            5322 bp    mRNA    linear   VRT 12-MAY-2025
DEFINITION  PREDICTED: Danio rerio GTPase IMAP family member 8 (LOC108179126),
            transcript variant X1, mRNA.
ACCESSION   XM_017354872
VERSION     XM_017354872.4
DBLINK      BioProject: PRJNA1248012
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_133178) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On May 12, 2025 this sequence version replaced XM_017354872.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_049306965.1-RS_2025_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/11/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5322
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /isolation_source="Zebrafish international resource
                     center"
                     /db_xref="taxon:7955"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="Fibroblasts and whole tissue"
                     /dev_stage="adult"
                     /ecotype="United States"
                     /geo_loc_name="USA"
                     /collection_date="2022-07-19"
                     /collected_by="National Human Genome Research Institute"
                     /genotype="Double heterozygous"
     gene            1..5322
                     /gene="LOC108179126"
                     /note="GTPase IMAP family member 8; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 13
                     ESTs, 1157 long SRA reads, 11 Proteins"
                     /db_xref="GeneID:108179126"
     CDS             331..2601
                     /gene="LOC108179126"
                     /codon_start=1
                     /product="GTPase IMAP family member 8"
                     /protein_id="XP_017210361.3"
                     /db_xref="GeneID:108179126"
                     /translation="

MRCFKEMFFCKCCRGAREEHDIIEGDKLLQDNDERTSSLQKRVDALKMREMTAGLNVVLLGKTGAGKSSSGNTILGRQAFITQKSVAQDVTVESGSFGELPVSVYDTPGLSDIEMSEEEIRQMINEKILQICSSGLCVFLLVIKADRFTEEDRKTVEKIEKILGENNQNNTWILFTRGDKLEGENMTIEKFIEETEELKTLVQKYEDRYHLFNNNKMKKEEEEEGGPSEQVKILFNKILKPYLDTMAGEKIWQQNTLKRKIPANIGAVSRVSGLPSRRIVLLGKSGVGKSAVGNTILGQKEFTSVMSTNSVTRVCSAAQSTVSGRSVSVVDTPGFFDTKMKPEELMMEIARSVYISSPGPHAFLIVFHVNTRFTEQEEQIPQMIELMFGEEVLKYSIILFTHGDLLDGESVEKLIEENFALRSLVQQCGGRYHVFNNKVNNREQVEDLQQKIDSMIQQNGGGHYTNQMYEDAQIFRQEEEEERKLQEEKQIQEEIEREIKETEERIKAEMEAENLKAERLSEEEQRRREKQRQEEIERVKKNTEERVRKEIKAKKETEERIRAENKAKLNEESGFLNFFSKYKHHFATAGHVVGGIAIGAAVLSGVGVGAAAGAGLAAFCAGVGSVSVAGAAVGGVVGGVVGGVAASKYEEEIKWKKRRREEEEREQQVDKKIQEEIERAIKEIDERFREEMVAKNLKAEKQSEEEQRRQEKQRLEEIKRVREKTEERIRAEIEAKKQRDGVRKNREDERNKNKRS"

     misc_feature    493..>966
                     /gene="LOC108179126"
                     /note="Members of the P-loop NTPase domain superfamily are
                     characterized by a conserved nucleotide phosphate-binding
                     motif, also referred to as the Walker A motif
                     (GxxxxGK[S/T], where x is any residue), and the Walker B
                     motif (hhhh[D/E], where h is a...; Region: P-loop
                     containing Nucleoside Triphosphate Hydrolases; cl38936"
                     /db_xref="CDD:476819"
     misc_feature    511..534
                     /gene="LOC108179126"
                     /note="G1 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    601..603
                     /gene="LOC108179126"
                     /note="G2 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    646..657
                     /gene="LOC108179126"
                     /note="G3 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(652..657,739..744)
                     /gene="LOC108179126"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206648"
     misc_feature    856..867
                     /gene="LOC108179126"
                     /note="G4 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    1159..1752
                     /gene="LOC108179126"
                     /note="AvrRpt2-Induced Gene 1 (AIG1); Region: AIG1;
                     cd01852"
                     /db_xref="CDD:206651"
     misc_feature    1177..1200
                     /gene="LOC108179126"
                     /note="G1 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    order(1186..1203,1240..1242,1534..1536,1540..1542,
                     1639..1644)
                     /gene="LOC108179126"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206651"
     misc_feature    1261..1284
                     /gene="LOC108179126"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206651"
     misc_feature    1264..1266
                     /gene="LOC108179126"
                     /note="G2 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    1321..1332
                     /gene="LOC108179126"
                     /note="G3 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    order(1327..1335,1363..1416)
                     /gene="LOC108179126"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206651"
     misc_feature    1531..1542
                     /gene="LOC108179126"
                     /note="G4 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    1615..1623
                     /gene="LOC108179126"
                     /note="G5 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    <1822..2595
                     /gene="LOC108179126"
                     /note="MAEBL; Provisional; Region: PTZ00121"
                     /db_xref="CDD:173412"
     polyA_site      5322
                     /gene="LOC108179126"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

ctagtttttaactccaccctcgctgtggctccgtttccgccttcagaataagacgtttagtctgaaattgaaagcagaaatctcacactgctggaagcttaccaagagcatctgaacacaacctgtattcccaagatcttgctaataaagggtaaaactgcaggaacggagaccatttgctcagacagtgccacctgctgttgggtttgaggaaactgcaggtccagaaagccaactgcacgctcagaccaagtagcaacatcagacacgtgaaattaaaagcagtgaatacaaccatctgaagctcacattcacacaaatctcaaagagatgagatgtttcaaagagatgtttttctgtaagtgctgcagaggagccagagaagagcacgacattatagaaggagacaaactgcttcaagacaatgatgagaggacaagctcactccaaaaaagggttgatgcattgaaaatgagagaaatgaccgccggattgaacgtggtcctgctgggaaaaacaggagccggaaaaagctcatcaggaaacacaatcctgggtcgacaagctttcatcacacagaaaagtgtcgcacaagacgtcactgtggagtctggatcattcggtgaactaccagtctctgtttacgacactccaggattatcagatatagagatgagtgaagaagagattcggcagatgatcaatgagaagatcctccaaatatgttcatcaggtctgtgtgtgtttctgctggtcatcaaagcagacagattcactgaagaagacagaaaaactgtggagaagattgagaagatcctgggagaaaacaaccagaacaacacctggattctgttcaccagaggagacaaactggagggagaaaacatgacgatagagaagttcatagaggagactgaagaactgaagacactcgtgcagaaatatgaggacagataccatctgttcaacaacaacaagatgaagaaggaggaagaggaggaggggggaccaagtgaacaagtaaagatactgttcaataaaatactgaagccttacctcgacacaatggcaggagaaaagatatggcagcagaatacactgaagagaaaaataccagcaaatattggagcagtctctcgtgtctccggtctcccctccagacggattgttcttctcggtaaatctggtgttggtaaaagtgcagttggaaacacaatcctgggacagaaagagtttacatctgtgatgagcacaaattcagtaacccgcgtttgttcagcagctcagtccacagtttcaggcagatctgtgtctgtagtcgacactcctggattctttgacacaaagatgaaacctgaagagttaatgatggagatcgccagaagtgtgtatatctccagtcctggacctcacgctttcctcattgtgtttcatgtgaacacgagattcactgaacaggaggaacagattcctcagatgattgagctgatgtttggtgaagaagtgttgaaatactccatcattctcttcactcatggagatctgctggatggcgagtcagtagagaagctgatagaggagaactttgccttaagatctctagtccagcagtgtggaggcagatatcatgtgttcaacaataaagtgaataacagagagcaggtggaggatctacagcagaagattgactcaatgatacagcagaatggaggaggacactacactaaccagatgtatgaagatgctcagatattcagacaagaggaagaagaggagagaaaactacaagaggagaaacaaatacaagaggagattgagagagagataaaggagactgaggagagaatcaaagcagaaatggaagctgaaaatcttaaagcagagagactgagtgaggaagaacagagaagacgagagaaacaaagacaagaggagatagagagagtgaagaagaatactgaggagagggttagaaaagaaattaaagctaaaaaggagacagaagagagaatcagagcagagaataaggctaaattaaatgaggagagtggctttttaaactttttttccaaatacaaacatcattttgccacggcaggacatgttgttggaggaattgctatcggagctgcagttttatctggagttggagttggagctgctgctggagctggtttagcagctttttgtgctggagtaggaagtgtttcagttgctggagctgctgttggaggtgttgttggaggtgttgttggaggtgttgctgctagcaaatatgaggaagaaataaagtggaagaagagaagaagagaagaagaagagagagaacaacaagttgacaaaaaaatacaagaagagattgagagagcaataaaggagattgatgagagattcagagaagaaatggtagctaaaaatcttaaagcagagaaacagagtgaggaagaacagagaagacaagagaaacaaagactagaggagattaagagagtaagagaaaagacagaggagagaatcagagcagaaattgaagctaaaaagcagagagacggagtaaggaagaacagagaagacgagagaaacaaaaacaagaggagttagagtgataaaagagacagaggagagagtcagagcagaaaatgaggctaaattaaacgagaagagtggatttttttatttttttaagagaggaagaagagaggaagaagagagaaaacaacaagttgacaaacaaatacaagaggagattgagagagtgataaaggagacaaaggagagatttagagaagaaatggaaactgaaaatcttaaagcagagagacagagtgaggaagaacagaaaagatgagaaaaacaaagacaagaggagatagagagagtgagaatggaaactgaggagagggtcagaacagagaaaatagctccattagcatctctatcatcaaaacaacaaaattacagaacaaaataggaaatacaaaacaattgaaacagttttatgatttttttttaagggggggttgtgatggtgttgttgcttgtagagctgttggtggtgtaattggtagagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagtttttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagtttttgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagctgatgttggtggagttgttgctttagctgatgttggtggagttgctgctttagcagtttgtggatttttagcaggctaatcagagatctgtttaattaagtttttgattaattctttaataattcaaaagatgtggccattaaggatgtgtgtctcaagaaaagtgatcttgagaactttatatctgaactggtgcggaccgtgctgaagttctcctgcacatgatgaacagtatgaattatgaattcttatgaattatttcattattaatagttgatacatgcatgggtgtttgaagaaatgttttcttgattaaagatttttggctgtgggtgcacaaatttgctttggtttaaacgacacattgatttaagataaaatactgtaacagtaattgaagaggttttgcctcaatgtttccatgcatttccataaagcatgtttattttctattgtgcattgaatgaaagtctatatttacaaaatgatgatatggtttgtgttcatcaaaaaaagaagttatctttttgtttcataataacacttaagttgtatttttctacagtgtcatatagacattattatcagattggtttatcctgctctggaaaagcatttgctgacatttaaactttgtaaatgtttcttgctctttgattgatgtgtatttttcttgttcagtgtctcttgttaactggtctcaatgagcacagctttatataaactctgttattgactttaattatgcatattcagaaaaattacatttgatttgatttca

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