LOCUS       NM_131160               3348 bp    mRNA    linear   VRT 03-APR-2024
DEFINITION  Danio rerio POU class 3 homeobox 2b (pou3f2b), mRNA.
ACCESSION   NM_131160
VERSION     NM_131160.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 3348)
  AUTHORS   England,S.J., Rusnock,A.K., Mujcic,A., Kowalchuk,A., de Jager,S.,
            Hilinski,W.C., Juarez-Morales,J.L., Smith,M.E., Grieb,G.,
            Banerjee,S. and Lewis,K.E.
  TITLE     Molecular analyses of zebrafish V0v spinal interneurons and
            identification of transcriptional regulators downstream of Evx1 and
            Evx2 in these cells
  JOURNAL   Neural Dev 18 (1), 8 (2023)
   PUBMED   38017520
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3348)
  AUTHORS   Okada,K., Aoki,K., Tabei,T., Sugio,K., Imai,K., Bonkohara,Y. and
            Kamachi,Y.
  TITLE     Key sequence features of CRISPR RNA for dual-guide CRISPR-Cas9
            ribonucleoprotein complexes assembled with wild-type or HiFi Cas9
  JOURNAL   Nucleic Acids Res 50 (5), 2854-2871 (2022)
   PUBMED   35166844
REFERENCE   3  (bases 1 to 3348)
  AUTHORS   Ladam,F., Stanney,W., Donaldson,I.J., Yildiz,O., Bobola,N. and
            Sagerstrom,C.G.
  TITLE     TALE factors use two distinct functional modes to control an
            essential zebrafish gene expression program
  JOURNAL   Elife 7, e36144 (2018)
   PUBMED   29911973
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3348)
  AUTHORS   Spikol,E.D. and Glasgow,E.
  TITLE     Separate roles for Med12 and Wnt signaling in regulation of
            oxytocin expression
  JOURNAL   Biol Open 7 (3) (2018)
   PUBMED   29530929
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3348)
  AUTHORS   Cosse-Etchepare,C., Gervi,I., Buisson,I., Formery,L., Schubert,M.,
            Riou,J.F., Umbhauer,M. and Le Bouffant,R.
  TITLE     Pou3f transcription factor expression during embryonic development
            highlights distinct pou3f3 and pou3f4 localization in the Xenopus
            laevis kidney
  JOURNAL   Int J Dev Biol 62 (4-5), 325-333 (2018)
   PUBMED   29877572
REFERENCE   6  (bases 1 to 3348)
  AUTHORS   Lohr,H., Ryu,S. and Driever,W.
  TITLE     Zebrafish diencephalic A11-related dopaminergic neurons share a
            conserved transcriptional network with neuroendocrine cell lineages
  JOURNAL   Development 136 (6), 1007-1017 (2009)
   PUBMED   19234064
REFERENCE   7  (bases 1 to 3348)
  AUTHORS   Tallafuss,A., Hale,L.A., Yan,Y.L., Dudley,L., Eisen,J.S. and
            Postlethwait,J.H.
  TITLE     Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb
            and rxrg during zebrafish development
  JOURNAL   Gene Expr Patterns 6 (5), 556-565 (2006)
   PUBMED   16448862
REFERENCE   8  (bases 1 to 3348)
  AUTHORS   Woods,I.G., Wilson,C., Friedlander,B., Chang,P., Reyes,D.K.,
            Nix,R., Kelly,P.D., Chu,F., Postlethwait,J.H. and Talbot,W.S.
  TITLE     The zebrafish gene map defines ancestral vertebrate chromosomes
  JOURNAL   Genome Res 15 (9), 1307-1314 (2005)
   PUBMED   16109975
REFERENCE   9  (bases 1 to 3348)
  AUTHORS   Hauptmann,G. and Gerster,T.
  TITLE     Combinatorial expression of zebrafish Brn-1- and Brn-2-related POU
            genes in the embryonic brain, pronephric primordium, and pharyngeal
            arches
  JOURNAL   Dev Dyn 218 (2), 345-358 (2000)
   PUBMED   10842361
REFERENCE   10 (bases 1 to 3348)
  AUTHORS   Liu,A., Majumdar,A., Schauerte,H.E., Haffter,P. and Drummond,I.A.
  TITLE     Zebrafish wnt4b expression in the floor plate is altered in sonic
            hedgehog and gli-2 mutants
  JOURNAL   Mech Dev 91 (1-2), 409-413 (2000)
   PUBMED   10704875
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from Y07905.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y07905.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3348
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="16"
                     /map="16"
     gene            1..3348
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="POU class 3 homeobox 2b"
                     /db_xref="GeneID:30397"
                     /db_xref="ZFIN:ZDB-GENE-980526-370"
     exon            1..3270
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1177
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="POU domain protein ZP-47; POU domain protein 47;
                     POU domain gene 47; POU class 3 homeobox 2"
                     /codon_start=1
                     /product="POU domain, class 3, transcription factor 2"
                     /protein_id="NP_571235.1"
                     /db_xref="GeneID:30397"
                     /db_xref="ZFIN:ZDB-GENE-980526-370"
                     /translation="

MATTASNHYNILTSSPSIVHSEPGSMQQATAYRDAQTLLQSDYSLQSNSHPLSHAHQWITALSHGEGGPWSSSPLGEQDIKPAVQSPRDEMHNSSNLQHQSRPPHLVHQTHGNHHDSRAWRTTTAAHIPSMATSNGQSLIYSQPSFSVNGLIPGSGQGIHHHSMRDAHEDHHSPHLSDHGHPPSQHQHQSHQSHHDHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSTSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAASEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGPLPGTEDVYGDTPPHHGVQTPVQ"

     misc_feature    41..124
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="propagated from UniProtKB/Swiss-Prot (P79746.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    296..394
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="propagated from UniProtKB/Swiss-Prot (P79746.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    491..655
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="propagated from UniProtKB/Swiss-Prot (P79746.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    638..862
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="Found in Pit-Oct-Unc transcription factors; Region:
                     POU; smart00352"
                     /db_xref="CDD:197673"
     misc_feature    875..877
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="Phosphoserine.
                     /evidence=ECO:0000269|PubMed:18307296; propagated from
                     UniProtKB/Swiss-Prot (P79746.1); phosphorylation site"
     misc_feature    917..1087
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     misc_feature    1079..1174
                     /gene="pou3f2b"
                     /gene_synonym="pou3f2; pou47; zp47; zp47pou"
                     /note="propagated from UniProtKB/Swiss-Prot (P79746.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
ORIGIN      

ggttcctttaataggagcgatcagtccggctccgagagtcatggcgactacagcatccaatcattacaatatcctcacctccagtccatctattgtacactcggagcctggaagcatgcagcaagctacggcttacagggacgcgcaaaccctgttgcagagtgactactcactgcagagcaacagtcacccgctcagccacgcgcaccagtggataacagccttgtcacacggagaaggaggtccgtggtcgtccagtcccctcggcgagcaggacatcaagccagcggtgcagagcccccgggacgagatgcacaattccagcaatctccagcatcagtcgcggccaccccacctggtacatcagacgcacgggaaccatcacgattcaagggcatggagaacaacgacggcagctcacatccccagcatggccacatcgaacggacagagccttatttattcgcagcccagcttcagcgtgaacggtctcattccgggcagcggccagggcatccaccaccacagcatgcgcgacgcgcacgaggaccaccacagcccgcatctcagcgatcacggccatccaccgtcccagcaccagcaccagtcgcaccagagccaccacgaccactcggacgaggacacgccgacctcggacgacttggaacagttcgccaaacagttcaagcagaggaggatcaagctgggcttcacgcaggcggacgtaggactagctttgggaacgctctatggaaatgtgttttcgcagaccacaatatgcaggtttgaggccctgcaactcagcttcaaaaacatgtgcaagctcaagcctttgttgaacaagtggttggaggaggcagactccacatctggaagccccacgagcttggacaagatagcagcgcaggggaggaaacggaaaaagaggacttccatcgaggtaagcgtcaaaggggctttggagagccatttccttaagtgcccaaagccagccgcgtcggaaattacttcactggcggacagtctgcagttggaaaaagaggtagtgagggtttggttttgtaacaggagacagaaagaaaaacggatgactcctcccggcggacctctaccgggtaccgaggacgtatacggagacacgccgccgcatcacggggttcagacgccagttcagtgaggggggagagaaaaaacactcaaaaaacacttacaaaacaaggacatatcttatcatattgactgcttcagtcttcatttatgattatgttcacattggaactatccaaagtgaaagcagctgcggtttagactactgaggcgggcgagcagattatatccgtcttcaatgtttctcaaaattcgtaggctactgctgcaacagagagggggaccgtgcgttccctgcgcgagcaaagagaacggttgttctgtgaatacccagcactgtgaaaagacgcagttttaaggtgtaaccctactatttatcaaacactttgagacgagcgaaatgtccctcaaacgcgagcatgggtgtcccatagccagttgtttacatcgagacgcattcactgcatttgcttttgcaggcttagcctgaaaagtgactagtgctgcagcatttgacaaatacacgccatttttacttttgttgtgggcgactgaaggtgaacatcgattctactggaaaacaacatcagtgtgacatgcatctatctacagtatttgactatttattttgatcaaaaggcctttaaacgtttaatattattattattattattattattattattattattattattatcattattatcaggctattttagatacattatatttacttatagaaacacagtgatgaggtgcaaggtcacactaagcagatgttgtagtcttggcgccaagaaattagtcacacacaattgattctagtctcttctagtctccgttttatcaatacggatgctctaaattgaaaagaaatcaaaagaaacttccagcatcgagctgcagacaggtcgccgaagggctagagaaagaaacctggcatttttcttcgataaaagacgaatcaccataaaatacaattgtttgacaggactccacacagtgctgtaaatattgtataatttttaaaggacatagctacgttattctctcacttgagcactttttcgtattattttgaattggggaaatattttagaggttttggtttatttttatttgggtctcgatttgttttgacattagagttggtctattttgcctttatatttatagtcattttagccgaatattgcttgctatctctcgcgtgagtcagttgctttttaacccacattcagctgcttttttataaattaatgagctgactttactatatgtttatgtatagtaaacaatgttcagttttcaacaatgttagcactattttctacccaacgaattcaatattatatatctcaaacatttgaatgtcttttttaattattttgaaatagaggttatttacacagtattgtggagaatgggaaaagcaaatgatgtgacatgcaatattttcatttcaagtcaaataattcttcattggtccatatgacaaagcggtttttgtgtattttataatttcatcaagcatatcaatcggaaacacaagcactattattgtcattattgctgttattattattattattattattattattattattattattattattaaatagtctccacgtttacccaataacggatctaaggatacttgggtttttgattgatcagtttagttttctttgtattttttttttcttgtgtgttttgtaattattcgttgtgttagtcccgcttcgcctttatagggacacgatgcagtgatgatttactgaaaatgtaaacactggaatatttggaaaaatgggaatatttttcccagtggcttgctatacgtgtgtaaatacagcaatcagaaattattattatttttattttcttattgtattatttttggttacattttaattcatatttttaatgtaaatctatttcactgaaattccagggacatctgtttttatctttttgttttgttccttaaaagaatcatttacatagattaattgatcaaactgtcatgtaattcaaagactgtgggagctatttatttgtcgttttatttcctctgtcagaaagactccatcaaacgttgaactggatgaaattgtgggataataaaatgcgcagaggttgtgatagaaatttaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

//