LOCUS       NM_001443043            5816 bp    mRNA    linear   VRT 04-SEP-2025
DEFINITION  Danio rerio RNA-binding protein MEX3B (LOC100331115), mRNA.
ACCESSION   NM_001443043 XM_073932129
VERSION     NM_001443043.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 5816)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000002.1.
            
            On Sep 4, 2025 this sequence version replaced XM_073932129.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01005078.1,
                                           SRR26395015.1639612.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476733, SAMEA4476761
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-309               JBMGRA010000002.1  61189577-61189885   c
            310-807             JBMGRA010000002.1  61188603-61189100   c
            808-5816            JBMGRA010000002.1  61177654-61182662   c
FEATURES             Location/Qualifiers
     source          1..5816
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="2"
                     /map="2"
     gene            1..5816
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="RNA-binding protein MEX3B"
                     /db_xref="GeneID:100331115"
     exon            1..309
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    228..230
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="upstream in-frame stop codon"
     exon            310..807
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..2111
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="mex-3 RNA binding family member D; RNA-binding
                     protein MEX3D"
                     /codon_start=1
                     /product="RNA-binding protein MEX3B"
                     /protein_id="NP_001429972.1"
                     /db_xref="GeneID:100331115"
                     /translation="

MPSPLFHPDIMEHESGQSGGGAREMEQDPRDEEHQEALRFALDQLSRMALEKVECLDGSSAGESCNGGGGYVDLQMMEHSSGSRESPGSCSPSPEYYGSGGGGGGGGYHMAGPHSSILGEQSSVLRKRSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRREDVEMAKREIISAAEHFSMIRASRCKAGASAPGSSGSLPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSREKDPVFEVTGMPENVDRAREEIETHITLRTGAFVDLQGDNDFHSNGTDVSLEGLGALGLSGALWSRATHNSAAPPPAMHRKTSFSNAESFSTTRRAADGGSPTSPFSTSSAGGSFSFGGDSTPSLPATNEDLGFEFGAANIWAPFVNGAKQPPQPVRRNSSGLSGGAVTPRLSPDPDHPLARRAQSDPLSTLSWLQNGGGGGSFSGGSSSSSGGSTTGYSSCSASSLPGGSPTDSEGGGSGVGISATMLSRLKAGALAGMVPRDCYVCCESEVTAALVPCGHNLFCMDCAGQICQSSDAECPVCHTPATQCIRIFS"

     misc_feature    747..965
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="first type I K homology (KH) RNA-binding domain
                     found in the family of MEX-3 RNA-binding proteins; Region:
                     KH-I_MEX3_rpt1; cd22423"
                     /db_xref="CDD:411851"
     misc_feature    order(774..779,783..791,795..809,813..821,828..830,
                     846..866,948..953,960..965)
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:411851"
     misc_feature    1035..1250
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="second type I K homology (KH) RNA-binding domain
                     found in the family of MEX-3 RNA-binding proteins; Region:
                     KH-I_MEX3_rpt2; cd22424"
                     /db_xref="CDD:411852"
     misc_feature    order(1071..1073,1077..1085,1089..1103,1110..1115,
                     1122..1124,1140..1160,1245..1247)
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:411852"
     misc_feature    1947..2105
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /note="RING finger, HC subclass, found in RNA-binding
                     proteins of the evolutionarily-conserved MEX-3 family;
                     Region: RING-HC_MEX3; cd16518"
                     /db_xref="CDD:438181"
     exon            808..5816
                     /gene="LOC100331115"
                     /gene_synonym="mex3d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gctgcacagacagacaaaggcggcggaccggaggaaccgacagaaagcgctctaagagtctccagacttccacgcgtgaaaacccgcagaaaaccatgagcagatcccgggtgcgagcggtgccgaggcgggacgagtgatccgagccgcgctggagctccagtttgaccgcgaatgctttaaaagcgactctttttctccaacgccccccaaaaacagttagcagctagcggttagccgtcccctccaccagcctcatcctccagaaaactgcggaaaacagcagccggcggcgcgggagcacacacgaaagcacagtctgctgggtgtctgatgcgcacgcggggtcgactatgccgagtcccctgtttcaccctgacatcatggagcacgagagcgggcagagcggcggcggcgcccgggagatggagcaggatccccgggatgaggagcaccaggaggcgctgcgcttcgccctggaccagctgtcccgcatggcgctggagaaggtggagtgtctggacgggagctcggctggggagagctgtaacggaggagggggttacgtggacctgcagatgatggagcacagcagcggctcgcgggagtcacccggctcatgctcgccctctcctgagtactacggctctgggggtggaggtggtggtggaggatatcacatggccgggccgcactcctccatcctcggggaacaaagctcggtgctccgcaagagaagtgtcaacatgaccgagtgcgtgcccgtgccctcctctgagcatgtggcggagatcgtcggtagacaaggttgcaagatcaaagcattacgcgcaaaaacaaacacgtacatcaaaaccccggtgcgaggagaagagccggtgttcatcgtgacgggacggcgtgaagatgtggaaatggccaaacgggagatcatctccgccgctgagcacttctccatgatcagagcctcacgctgcaaagccggcgccagcgctcctgggtccagcggctcactccctggcccgccaaacctgccaggacagaccaccatacaggtgcgcgtgccctacagagtcgtgggcttagtagtaggccctaaaggagccacgatcaagcgcatccagcaacagacgcacacctacatcgtaacaccgagccgagagaaagatcctgtgtttgaggtcacaggcatgccagaaaacgtagaccgtgcccgagaggagatcgaaacacatataactctacgcaccggcgcattcgtggatctccaaggcgataatgacttccatagcaacgggacggatgttagtttagagggtttgggtgcgctgggattgagcggtgctctttggtcacgtgcaactcacaattctgcggctccgccgcctgccatgcatcgcaaaacgtccttctcaaacgcggagtcgttttccactacacgccgcgcagcagacggaggaagcccgacgagtcccttcagcaccagcagcgcagggggaagcttctcttttggaggcgactcgactcctagtttgccggcgaccaatgaagatttgggtttcgagtttggcgctgctaatatctgggcgccgtttgttaacggtgcaaagcagccgcctcagcctgtccggcgcaatagcagcggcctcagcggtggagctgtaactccacgtctatcacccgaccccgatcaccctctcgcccgcagagcccaaagcgacccgctcagcactctctcctggctccaaaatggcggcggcggcggatcgttttctggaggaagcagcagcagtagtggaggaagcacaaccgggtattcgtcctgctccgcgtcgtcgcttcctggtggatctccgaccgactctgaaggcggcggcagtggtgttggcatctctgctactatgctgagtcgcctgaaagcaggcgcgctagctggaatggttcctcgagattgttacgtgtgctgcgagagcgaggtgactgctgcgctggtgccctgcggacacaatctgttctgcatggactgcgccggtcagatctgccagtcttctgacgccgagtgcccggtgtgccacactcctgccacacagtgcatccgcatcttctcttaaagaccgccttcataggagcgaccgcaatgattagatatgacactattcttgatttattgacaataataataatgatgatgatgataataatgacgtcgttacccactcaagtacttgttttatttgtcttactagcgctcatgttcatattcggtgggtttttttctccagctcatgcttccctttttctactcgcagatatttttcaacttttacgctgcacttttttctaatgcattgtgtttgttttttagagggttgccgatttttaaattattttttaaaaattgtttttgtgtgtgtgtgtgtgtgtgtgtgtgcattttttaaatgcagcgccagactgcgaacgctcatttagaccaaaacgttgagaggttattcctgtaacacttaatatttatacgtactagttgatgttgaatctgagatagctagagtagtacatgttataagtatcataaccgtgcattttctctttttgccacactaccttaaaacacgacgatgacggtgtgtgttgttcattccagcagtctacactcctgaaacagggttgccagtatttggatgaatctgttacgcttttctgtgctgaagtgaacggcgccctccatcttcaactcgaatgtttttttcgtttgtgaatgcgtgtgcgtgtgtgtgtgtgtggtcatcctgatttgtgcactgcgacacactgaaatgtctttggctggagttggagtctgtcttccggctgtcgcacttagtcccgctgtggttttcctcgtccgccgcctataaacgtagccgctgtttctgacatccgtagccccgttttacacacaacaagccatgaactcactctaaagggcttccggttacacactacacttcaggttttcgctaataaacaggatcttcagtcccactcgagtctgtgtggcagctaaatcacgcagggcttccgtacgttgtttttcctgaaacgcgggggactttttgtttttgtttttcagacatcctcgtttgcatgagttgtacagattccattgaggactattaaatgtgccagactttgagagcagtcagctagagctgtggtgatgatcgcaggcattgcaaatcgagacagtattttgcatcgattctgaaatttcccaaatgcattgcgatcctctcttgaatgcgttctgaaattaggtttgaccaacagatggcgtcgtatgctttacagacagcctccaattcattcacgcaccactcaaagtattgtaaggaaggtttaagggaattacaggagcatgcatagtaagctgtttacgttaatctcatggaataaaagtcaaggtgcacctacatttgaccacttgcttgactaatgcacaatacagccttatttctgggtatttgagtctgctgttagctagcatttaagcgccatctgctgttataaactagcctagagcgccatcttctgttaaaaactaacttagagtgccatctgctcttataaaactagcttacagcgccatctgctgttattaaactaggcaagagcgccatctgctgttataaaactagcttacagcgccatctgctgttattaaacttggcaagagcgccatctgctgttataaaactagcctacagtgccatctgctgttaaaaaactaggcaagagcgacatctgctgttattaaactaggcaagagcgccatctgctgttaaaaaactaggcaagagcgccatctgctgttattaaactaggttacagcgccatctgctgttattaaactaggcaagagcgccatctgctgttataaaactagattacagcaccgtctgcggttaaaaaaaagctagcctagatcaccatctcctttctacatctagcctagagcaccatcctctgttaaaatctagcctagtgcgccatctgctgttataaactggcctagagcatcgtctgctgttaaaactagcttagagcacaatgtgctcttacaaaatttgcctacagcgccatctgctgttataaaactagcctagagcgtcacctgctttttacatctagcctagagcaccatctgctgttcataaccatcctagagcaccatttgcagtttacaaactagcctagagtgccatctgcttgttacatctagcctaaagtgctatctgctgttaaaaactagcctagagcacaatctgctgtttaaaaactagcctagagcgccatctgctttcgacaattagcttgcattccatctgctggtaaaaactagcctagagcaccatctgctttttaacaactagctgagagcgccattttctgtttaaaaactagcctagagagcgccaactgtagtttaaaagctagcctgctgcgccatctgctttttacatctagcatagatcatcatctattgttcataaccatcctagagcatcatttgcagtttaaaaattagcctagagcgccatctgctttttaaattaagcctagagcgccatctactgttcagaaccatcctagggcaccatgtgcggtttaaaatctagcatagagcgccatctgctgtccaaaactagatcagagagaattgcgatgtgttgtgaaaatctcagaaacgatccacgaattgcactgctaaaatgaaaaacaataataatactaataatgaacgcatcatcacagccctacagtaaacggtgccttggtggtgaaagtcgctgccgagaaaacgaagattgtgttgaaccttctccgctcttccacttttgaagattggcttcggagtatttgtacagaatatctgagccttgtttagtttgtttgggactgtgctttggaaacacaagcgtgttgtcggttgcgaggaacagaagctagctagttttcggttgtgtgtgtgtgtgtgcgcgtgtgtgttttggcgatgaaggtcatgttgacctgaggttgaatcttctcttgttttcctctaaaaggcttcaaacagggttcactgaggcgaatctcaggcatcggaacgacgtcagacgctgtttccccatcaatcattttcttgccctgaaatcgctctactctttcctttacgttcgctttaattccttttgtacgccgaaccaaaagtgatttcaataacggagtttcaggcctaattgtaaatatcctggatacaatcattgggattagttttttccacagctgaaaggttaatgtagtttttaagaacatgtatcattatttgtaagttaaactctctgcatgtcttgaagccatgaggcgttagctaataatttttctaaaaacgcaaaggcaaaaaaaaaaagaaattaaaatggacaaaccttttttacacattttatttttacaatttatttgctaaccttgacatgaatatcccagattataatgtgaccctttttattacagcaaagttctctttattttccatgtttctgttctttcctgtgtattacatataggcaatttataacaaaatgagaaaaaattattgaagaaattttaaaattgaaatatattttatttgaaagtttatggaccttttaaccgcgagctggaacacttgtgtacgcggcgtatcatttgagctgacttgacggttatgagaaatgtatcaagagttttattttttatgcttctttaataaaatcttgtttttttgtttccgtttttgtactgtaaaacaataa

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