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Previous release (v1)
2025-01-31 06:40:57, GGRNA.v2 : RefSeq release 227 (Nov, 2024)
LOCUS NM_001039828 3238 bp mRNA linear VRT 03-APR-2024
DEFINITION Danio rerio solute carrier family 15 member 2 (slc15a2), mRNA.
ACCESSION NM_001039828 XM_679532
VERSION NM_001039828.1
KEYWORDS RefSeq.
SOURCE Danio rerio (zebrafish)
ORGANISM Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE 1 (bases 1 to 3238)
AUTHORS Vacca,F., Gomes,A.S., Murashita,K., Cinquetti,R., Roseti,C.,
Barca,A., Ronnestad,I., Verri,T. and Bossi,E.
TITLE Functional characterization of Atlantic salmon (Salmo salar L.)
PepT2 transporters
JOURNAL J Physiol 600 (10), 2377-2400 (2022)
PUBMED 35413133
REFERENCE 2 (bases 1 to 3238)
AUTHORS Meirelles,M.G., Nornberg,B.F., da Silveira,T.L.R., Kutter,M.T.,
Castro,C.G., Ramirez,J.R.B., Pedrosa,V., Romano,L.A. and
Marins,L.F.
TITLE Growth Hormone Overexpression Induces Hyperphagia and Intestinal
Morphophysiological Adaptations to Improve Nutrient Uptake in
Zebrafish
JOURNAL Front Physiol 12, 723853 (2021)
PUBMED 34539447
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 3238)
AUTHORS Buerger,A.N., Schmidt,J., Chase,A., Paixao,C., Patel,T.N.,
Brumback,B.A., Kane,A.S., Martyniuk,C.J. and Bisesi,J.H. Jr.
TITLE Examining the responses of the zebrafish (Danio rerio)
gastrointestinal system to the suspected obesogen diethylhexyl
phthalate
JOURNAL Environ Pollut 245, 1086-1094 (2019)
PUBMED 30682743
REFERENCE 4 (bases 1 to 3238)
AUTHORS Barat,A., Sahoo,P.K., Kumar,R. and Pande,V.
TITLE Solute carriers (SLCs) identified and characterized from kidney
transcriptome of golden mahseer (Tor putitora) (Fam: Cyprinidae)
JOURNAL Comp Biochem Physiol B Biochem Mol Biol 200, 54-61 (2016)
PUBMED 27287540
REFERENCE 5 (bases 1 to 3238)
AUTHORS Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
TITLE RFX transcription factors are essential for hearing in mice
JOURNAL Nat Commun 6, 8549 (2015)
PUBMED 26469318
REMARK Publication Status: Online-Only
REFERENCE 6 (bases 1 to 3238)
AUTHORS Tian,J., He,G., Mai,K. and Liu,C.
TITLE Effects of postprandial starvation on mRNA expression of
endocrine-, amino acid and peptide transporter-, and metabolic
enzyme-related genes in zebrafish (Danio rerio)
JOURNAL Fish Physiol Biochem 41 (3), 773-787 (2015)
PUBMED 25805459
REFERENCE 7 (bases 1 to 3238)
AUTHORS Wang,Y.C., Lin,C., Chuang,M.T., Hsieh,W.P., Lan,C.Y., Chuang,Y.J.
and Chen,B.S.
TITLE Interspecies protein-protein interaction network construction for
characterization of host-pathogen interactions: a Candida
albicans-zebrafish interaction study
JOURNAL BMC Syst Biol 7, 79 (2013)
PUBMED 23947337
REMARK Publication Status: Online-Only
REFERENCE 8 (bases 1 to 3238)
AUTHORS Romano,A., Kottra,G., Barca,A., Tiso,N., Maffia,M., Argenton,F.,
Daniel,H., Storelli,C. and Verri,T.
TITLE High-affinity peptide transporter PEPT2 (SLC15A2) of the zebrafish
Danio rerio: functional properties, genomic organization, and
expression analysis
JOURNAL Physiol Genomics 24 (3), 207-217 (2006)
PUBMED 16317081
REMARK GeneRIF: We characterized the functional properties of a novel
zebrafish peptide transporter orthologous to mammalian and avian
PEPT2, described its gene (pept2) structure, and determined mRNA
tissue distribution
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from DQ192597.1.
On Mar 27, 2008 this sequence version replaced XM_679532.2.
##Evidence-Data-START##
Transcript exon combination :: DQ192597.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA3505370, SAMEA3505371
[ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..3238
/organism="Danio rerio"
/mol_type="mRNA"
/db_xref="taxon:7955"
/chromosome="9"
/map="9"
gene 1..3238
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="solute carrier family 15 member 2"
/db_xref="GeneID:556684"
/db_xref="ZFIN:ZDB-GENE-030131-5866"
exon 1..104
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
misc_feature 53..55
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="upstream in-frame stop codon"
CDS 89..2248
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="peptide transporter PEPT2; solute carrier family 15
(oligopeptide transporter), member 2; solute carrier
family 15 (H+/peptide transporter), member 2; peptide
transporter 2"
/codon_start=1
/product="solute carrier family 15 member 2"
/protein_id="NP_001034917.1"
/db_xref="GeneID:556684"
/db_xref="ZFIN:ZDB-GENE-030131-5866"
/translation="
MGKMKDKDVDAEKYEKAQRSPKLCGTNYPVSIAFIVVNEFCERFSYYGMKAVLTLYFMNYLHWDKNLSTAIYHAFSGLCYFTPLLGALIADSWLGKFKTIIYLSIVYVIGHVVKSVGAIPDVGDSTVHIALSMVGLGLIALGTGGIKPCVAAFGGDQFDEDNIDERRKFFSIFYMSINAGSVLSTIITPILRGDVQCFGGDCYALAFGVPAALMVIALVVFISGSGLYKKSPPEGNVLVRVCKCIGFAISNRWTNSKKSPKRSHWLDWAEEKYSKRLIQEIKMVCRVLVLYIPLPMFWALFDQQGSRWTLQATRMNMDFGGGFIIKPDQMQMLNALLILVFIPIFDMGIYPLVGLCRIKLTPLKKMATGMILAALAFCAATAVEVYVIKTVVEPPPAKESLVQVYNLMDSDVTVQFPAHNVFSEPLKPYEEPSGYSSLPLTGESQLQNVVVSHNGVNYECRLTFTERMAYSLLLHPPAQSGGSVCNLVKDHITKSETGAAYIRFINTHTENINVTVGTEEVHASANYGISRNISVPRGEYNKAVCVTDSKEYEINLGLLDFGAFYTVILSETGNNLAIKKMEDIQANNIHIGWQIPQYVFLTAGEVMFSITGLEFSYSQAPASMKSVLQAGWLMTVAFGNVIVLIVAEGAGMEQWVEFLLFAALLVAVSIIFSIMAYFYTYVDPDQLDKLFKEEGDGGKVESSKKDELSLGEIPKQTKM"
misc_feature 218..2125
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="Peptide:H+ symporter (also transports b-lactam
antibiotics, the antitumor agent, bestatin, and various
protease inhibitors); Region: 2A1704; TIGR00926"
/db_xref="CDD:273343"
misc_feature 218..271
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 284..286
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (B0S6T2.1); glycosylation site"
misc_feature 296..358
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 386..448
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 464..526
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 596..658
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 692..754
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 929..991
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 1091..1153
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 1190..1252
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 1253..1870
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
Region: Extracellular domain (ECD).
/evidence=ECO:0000250|UniProtKB:Q63424"
misc_feature 1529..1531
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (B0S6T2.1); glycosylation site"
misc_feature 1625..1627
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (B0S6T2.1); glycosylation site"
misc_feature 1682..1684
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (B0S6T2.1); glycosylation site"
misc_feature 1871..1933
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 1967..2029
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 2060..2122
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
transmembrane region"
misc_feature 2171..2245
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/note="propagated from UniProtKB/Swiss-Prot (B0S6T2.1);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
exon 105..151
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 152..239
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 240..381
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 382..474
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 475..574
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 575..665
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 666..743
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 744..826
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 827..910
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 911..1000
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1001..1045
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1046..1081
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1082..1170
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1171..1252
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1253..1378
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1379..1549
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1550..1596
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1597..1704
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1705..1801
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1802..1945
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 1946..2050
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
exon 2051..3220
/gene="slc15a2"
/gene_synonym="wu:fc84g07; wu:fi22a10; zgc:152684"
/inference="alignment:Splign:2.1.0"
ORIGIN
agtctctgtggagggacggacttggccgcgtgttcaggaatccactacacgttgagtgtccaagtacacacttggattcattaaagagatggggaaaatgaaggacaaagatgttgatgcagagaaatatgaaaaagcacagcgctcaccgaaattatgtgggactaactatccagttagcattgccttcattgtggtcaatgagttctgtgaaagattctcttactatggaatgaaagcggtgctgacgctttacttcatgaactacctgcattgggacaagaatctgtctacagctatttaccatgcattctcaggcctgtgttacttcactccacttctgggggccttgatagcagactcatggttggggaagttcaaaaccatcatctatctgtctattgtgtatgtgattggccatgtggtcaagtctgtcggggccattcctgatgtgggggacagcactgttcatatagctctgtcaatggttggtctgggcctcattgcattagggacaggagggatcaaaccctgcgttgcagcttttggtggtgaccagtttgatgaagacaatatagatgagcggagaaaattcttctccatcttttacatgtcaatcaacgctggaagtgtcttatccactattatcacaccaatactaagaggtgatgtgcagtgttttggaggagactgctacgccctggcctttggagttcctgcagctttaatggtcatcgccttagtggtgtttatttctggaagtggcctatacaagaaaagtcctccagagggaaatgtcttggtgcgtgtctgcaaatgtatcgggtttgctataagcaatcgatggacgaattccaagaagagcccaaaacggagccactggctggattgggcagaggagaagtactcgaaacgactcattcaggagattaaaatggtgtgcagggtgctggttctttatattcctttgccaatgttttgggctctctttgaccagcaggggtcacgctggactcttcaagctactcgaatgaatatggattttggtggaggcttcataataaagcctgatcaaatgcagatgctgaatgctttgctgattctggtgtttattccaatctttgacatgggcatttatccacttgtaggcctctgtcggatcaaactcactccgctaaagaagatggcgacgggcatgattcttgctgcacttgccttctgtgctgcaactgctgttgaagtttacgtcattaaaaccgtggtggagcctcctcctgccaaagagagccttgttcaggtttacaatcttatggattcagatgtcacagtgcagtttccagcacacaatgtcttctcagagccacttaaaccatatgaggaaccttcgggatactcaagtcttcctcttaccggagaatctcagctgcagaatgtggttgtcagtcacaatggtgtgaattacgagtgcagactcacgtttacagagcggatggcttacagtctcttactgcaccctcctgcacagtccggcggctctgtatgcaatctggtaaaagatcacatcaccaagtctgaaaccggggctgcgtatataaggtttatcaatacgcacacagaaaatatcaacgtaacagttggcactgaggaagttcatgcgtctgcaaattatgggatttctcgcaatataagtgtaccaaggggagaatataataaagctgtttgtgtaactgactccaaagaatatgagattaacctgggacttcttgattttggtgctttctacacagtcatactctcagagacgggcaataatctagcgatcaaaaagatggaggacatccaagccaacaacattcacatcggctggcagattccacagtacgtgttcctcacagccggagaagtcatgttctccatcaccggtctggagttctcctactcacaggcaccggcgagcatgaaatccgttctccaggctggatggcttatgaccgtggcatttggaaatgtcattgtcctgattgtggcagaaggggctggcatggaacagtgggtggagtttctgctttttgctgcactcttggtggcggtcagcatcatcttctccatcatggcttatttctacacctatgtggatccagatcagctagacaagctttttaaagaggagggagatggcgggaaagtggaaagtagtaagaaagatgagctttctttgggtgaaataccaaagcaaaccaagatgtagcaaactgatgttcggagtattgaactattcagatctgtgaataagctaatcgactttatttttttcacatcggactgtgtattttcttctagggcctttatgtggcattatgctgagctttactgatcagggatcaaattccagctgaattaggagacatttgttgtgctgcagcaatgtaatgaacgtggtaccttgcacaaagaaatcatttatagagatgtaatgcttaagaatgtgatggactttacacttcatatgtttggggttggtaagattcaatgaagtctcttataatcttcaagaccatttatttgacttatcaaaagtaagacagcattgctctcataaatgaactggttcagtataattgatcataagttacatcatgtgtaaaatgaaattctgctgattttaaagctgaatattgatccttgtgaacagtgatccttcaaaatcatttcgatatgctgatttggtgcttaaacatttcttgttattcttggtgaaaatagttgtgctgctttaatattttcgtcaaaaccattattcttttttttctgtattctttaaaaatagaaagttattttctttgccacaatgtaaaagcttgtgatcaattaatattcatttattagaaaaaaaagaaaaacaaaagtcttactgatcccaaacacttgaacatttacactatagaaatatcagtcaataactattattccagtaatgcctatttgcacaagtcaaagctcacgtttgtacataatgcctgtcagtcttgctctgttcagagggtactccttttctagatgacagtttattaaaacagactgctccggtttcatgtattaagtcgaaaggctggtgaatgttgtcagggacggagtgattcatgacactctttgaaataaacttgtatatatttgtaacacaattattatgtacataattacaccagaactgatttctgaaaaaaaaaaaaaaaaaaaa
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]