LOCUS       XM_041479151           14421 bp    mRNA    linear   VRT 06-MAY-2021
DEFINITION  PREDICTED: Pyrgilauda ruficollis argonaute RISC catalytic component
            2 (AGO2), transcript variant X2, mRNA.
ACCESSION   XM_041479151
VERSION     XM_041479151.1
DBLINK      BioProject: PRJNA703052
KEYWORDS    RefSeq.
SOURCE      Pyrgilauda ruficollis (rufous-necked snowfinch)
  ORGANISM  Pyrgilauda ruficollis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea;
            Passeridae; Pyrgilauda.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024526377.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Pyrgilauda ruficollis Annotation
                                           Release 100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14421
                     /organism="Pyrgilauda ruficollis"
                     /mol_type="mRNA"
                     /isolate="IOZ18807"
                     /db_xref="taxon:221976"
                     /chromosome="Unknown"
                     /sex="pooled male and female"
                     /tissue_type="blood"
                     /altitude="4200 m"
     gene            1..14421
                     /gene="AGO2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 ESTs, 35 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:121359884"
     CDS             138..2729
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X2"
                     /protein_id="XP_041335085.1"
                     /db_xref="GeneID:121359884"
                     /translation="

MYPGAPSAGPVLTPPPPLPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVAIKWMSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"

     misc_feature    423..647
                     /gene="AGO2"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    675..827
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    828..1190
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(984..986,1029..1031,1071..1073,1083..1085,
                     1137..1139,1158..1160,1164..1166)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1323..2600
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1734..1736,1746..1748,1782..1793,1800..1802,
                     1824..1826,1833..1835,1845..1847,1857..1859)
                     /gene="AGO2"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1938..1940,1944..1946,2154..2156,2568..2570)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

tttccttccccctcccctttccttcctcctcctcctcctccccttcccccgacagcgtagccggggctcgggctcgctccctcccccgtgccctcccctggagccgccgccgcctccgccgccgcacacacggagacatgtacccgggagccccctccgccggacccgtgctgacacctcctcccccattgccaccaccaatacagggatatgcctttaaacctcctcctcgaccagattttggcacttctgggagaacaatcaaactgcaggccaacttctttgaaatggacattcctaaaatagatatctaccattatgaattggatataaagccagaaaaatgtcctagaagagttaacagagaaatagtggagcatatggttcagcactttaaaacccagatttttggggatcgcaagccagtgtttgatggaagaaaaaacctttatacagccatgccacttcccattgggagagataaagtggagctggaggtcacgctgccaggagaaggaaaggacagaatatttaaggtggccatcaagtggatgtcctgtgtgagcttgcaggctttgcatgatgctctctctggccgcctgccgagcgtcccgtttgagaccatccaggccctggatgtggtcatgaggcacttgccttccatgaggtatactcctgtggggagatctttctttacagcatcagaagggtgctcaaatcctttgggtgggggcagagaagtttggtttggcttccatcagtcagtcagaccttcattatggaaaatgatgctaaatattgatgtgtctgcaactgcattttacaaagcacagccagttattgagtttgtctgtgaagttctggacttcaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtaaagtttaccaaagaaataaaaggtctgaaggtggagataacacactgtggacaaatgaaaaggaagtacagagtgtgcaatgtcaccagacgaccagcaagtcaccaaacattcccacttcagcaggagaatggacaaacagttgaatgcactgtagctcagtattttaaggacaggcataaattggttttacgctaccctcaccttccatgtttacaagttggacaggagcagaaacacacataccttcctctagaggtgtgcaacatagtggcaggacaaagatgcataaagaaactcactgacaatcaaacttccactatgattcgagccactgccagatcagctccggaccggcaggaagagatcagcaaattgatgcggagcgccagtttcaacacagacccttacgtccgagagtttggcatcatggtcaaggatgaaatgacagatgtgactggcagagtccttcagcctccctcaatcctctatggaggcaggaataaagcaattgctacaccagtgcaaggtgtctgggacatgaggaataaacaatttcacactggaattgaaataaaggtttgggcaattgcctgctttgctccccagcgccagtgcactgaagttcatctgaagtccttcacagagcagctgaggaagatttccagggatgctggaatgccaatccaggggcagccctgcttctgtaaatacgcccagggagccgacagtgtggagcccatgttcagacacctcaagaacacttacactgggctgcagcttgtcgtggtcattttgccaggaaaaacaccagtctatgcggaggtgaagcgcgttggtgacacggtgctgggaatggccactcagtgtgtgcagatgaaaaacgtccaaagaacaacaccacaaactctgtccaacctttgcttaaaaataaatgtcaaattaggaggtgtaaataatattctactgccacagggaagaccccctgtattccaacagcctgtcatattccttggtgcagatgtaactcacccaccagctggggatgggaaaaagccttccattgctgcagttgtaggaagcatggatgctcatcccaaccgttactgtgccactgtgcgggtgcagcagcaccgccaggagatcatccaggacttggctgccatggtcagggagctgctgatccagttctacaaatccaccaggttcaaaccaactcgaatcatcttctacagggatggtgtttctgaggggcagttccaacaggttctccaccacgagctgctggctatcagggaggcttgcattaaactggagaaggattatcagcctggcatcacatttatagtggtgcagaagaggcaccacaccagactcttctgcacggataaaaacgaacgggttggaaaaagtggaaacattccagctggtaccacagtggacacaaaaatcacccacccctcggagttcgacttctacctgtgtagtcatgctgggattcagggaacaagcagaccttctcactaccacgtgctgtgggacgacaatcgcttctcgtcggacgagctgcagatcctcacctaccagctgtgccacacctacgtgcgctgcacgcgctccgtctccatccctgccccggcctactacgctcacctggtggccttcagagccaggtaccatctggtggataaagaacacgatagtgctgaaggaagccacacttctggccagagcaatggcagagaccaccaagcacttgctaaggcagtccaggtgcaccaggacacgctgcgcacgatgtactttgcttgacatgttttaatgttcagcggctcccgacaaggcagagttggattcacaccagaccagctgcacttagaccaacagatgccccaccccagggacagccagcaatgagtgatgcatctttattcctttctttcccatttgcaaggaagccttccgtccagaatttcagacttgatcacaaactgcattcttgtaccaaaccccactgttgtcggaaatgtggtttgccaaaaaatctctgagctgcttggtataaaacagacccagattttataattaaatcaagagctgcaatctcagggcttagggaagaaaaacaaaaaaaccaaaccaacaactcaacccacaaaactcctcattcagtttgctgttcattgagttgcttttgataatttggaaagatctaattcatactaaggtttgatgagctaaaacgctgtgaatcagcttttagtacaaaggaaagcaaatcatcttttgagtatttatgaagccttgactattctagatgcatttacaaaatttttattttcaaaataagagcgtgacaaaattctggtttctaattgtcttataaagattattctcagattattctctgtgtgtctaaggacaaatgtattttctgaagcttgttcttgaatgttttttattgtgctgcattttaaaatgtttttcatagactaaagatgaatttaaaaaaaaaaaaagagagtaaacctgtacttaagcttttaatagctccagttagattggcagaagaaaatgtgccatttaaaaaaatttgtaaagatttttttttaaatcatactgacagctaactttaggatttgtcatacaggactgtgacatttactttccaaagtctctaaagaatacgggtctgtggtgatgaatacagtacaatcctttttcactgttgagttaatgtaaattttatatatgtttcacagtattaatgtgatagactagatgctattatttatttttatttactaaggagtgctcattatacttctgttaacatatcaagaatgctttgaacttagaaagtaaaatcctttttgtggggacattactcttcaaatgcaaaaaaaaaagaaaatatgcaatcgatgtggtgagaggagagagatgcagccagtgtctgttgtagcttgggatttgcagaaaggctttttcaatgtgcacacaacacagcaggttttacctctgcggttcagacgcacacaagaccaacatcctacattcattcaagcacaaaacaattgtattttatttatatgttgagtagtggtgaagcaggagctctgctagaggagagtggctcgctggaagttaggcagaagtcagagaatctatgcagtaaagataaaaattaggagattgaagtttacttagggagggaggtgaagctctcttcattatgcataagatctgtaggaaatgtgagagttttgccattctcttaggagaagcattaattaaaactgctaattatgagacagatgcttctgttagtttgcacactggattcataaaaaccataacacacatgtaaaccattgcactaatgacaatgccacgagcaggtttaggagaaaatggaaaaagcccaggaaagttgtttatgctgacttgatcttgtttgtttttccatgggataactgaaataagatgctgagaggcaggttggaaaaccttcattctcctccactgatggattttgctttgtcttttcccttttctccgagcagctgctcagtctctttggacacttttacctctggccactgggatgggcaagtagctttaacccatgcagagctctgggccacagagcaggtcagctgcaaccaggtggtgttggataagctagaaaatgcccagcctttgctgcataaagacttttaggtacataattccagtccagatcttcaccttgtagcagtgtgaaggttgtcggtgttttgtaggtgaaatgtaaaacctgttaatgaaataatcatatttgtactattctaattgggtgattaggctgctggctcagagtatcttcttggtcatagttctataaattcagatttctgtaaatttgaagcaaatcctaggtagcattgtctgtcttgctgtgtgccagcgaggttgtacctacctcccctcaagcacccctaagctgcagatcctccccgtggtgggtgtgttgcacttctctgtgtttccttcagagctttcctatttcagtgaagatattcatttggcagagttttatat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