LOCUS       XM_030038628           14243 bp    mRNA    linear   VRT 03-MAY-2021
DEFINITION  PREDICTED: Aquila chrysaetos chrysaetos argonaute RISC catalytic
            component 3 (AGO3), transcript variant X2, mRNA.
ACCESSION   XM_030038628
VERSION     XM_030038628.2
DBLINK      BioProject: PRJNA556399
KEYWORDS    RefSeq.
SOURCE      Aquila chrysaetos chrysaetos
  ORGANISM  Aquila chrysaetos chrysaetos
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
            Accipitrinae; Aquila.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_044019.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 30, 2021 this sequence version replaced XM_030038628.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Aquila chrysaetos chrysaetos
                                           Annotation Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14243
                     /organism="Aquila chrysaetos chrysaetos"
                     /mol_type="mRNA"
                     /sub_species="chrysaetos"
                     /db_xref="taxon:223781"
                     /chromosome="16"
     gene            1..14243
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 32 ESTs, 54 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:115351665"
     CDS             178..2760
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X2"
                     /protein_id="XP_029894488.1"
                     /db_xref="GeneID:115351665"
                     /translation="

MEIGSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    394..678
                     /gene="AGO3"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    706..858
                     /gene="AGO3"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    859..1221
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1015..1017,1060..1062,1102..1104,1114..1116,
                     1168..1170,1189..1191,1195..1197)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1354..2631
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1765..1767,1777..1779,1813..1824,1831..1833,
                     1855..1857,1864..1866,1876..1878,1888..1890)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1969..1971,1975..1977,2185..2187,2599..2601)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

cgccgccgcctgaagggagcggagcggagctccgggcggccgtaggcgaagcgccgggccgcggcctgcggggagcggggcgggccgccgcccagcgttttagccccgagccggccgccgggcccggttgtaagcggcggatcccgcagccctcggcggctgcgcccagctccatgaatggaaatcggcagcgcaggacccgtcggggcacagcccctactcatggtgcccagacgtcctggctatggcaccatgggcaaacccattaaactgctggccaactgcttccaagttgaaatcccaaagattgatgtctacctctatgaggtggatatcaaaccagataagtgtcctcgaagggtgaacagggaggtggtggactcaatggtgcagcattttaaagtgacaatatttggggaccgtagaccagtttatgatgggaaaagaagcctctatacagccaatccgcttcctgtggccactactggggtggatttggatgtgacattaccgggagaaggtggaaaagatcgtcccttcaaagtgtcaataaagtttgtttctcgggtgagctggcacttgctgcatgaagttttgacaggaagaaccttgcctgagcctctggaactagacaaacctatcagcactaaccctgttcatgctgtcgatgtggtgctacgacacctaccctccatgaagtatacccctgtgggccgctcctttttctcagctccggaaggctatgatcaccccttgggtgggggtagggaggtctggtttggattccatcagtctgttcggcctgccatgtggaagatgatgctcaatattgatgtttctgccactgccttctataaagcacaacctgtaattcagtttatgtgtgaagttcttgacattcataatatcgatgaacaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaagggtctaaaggtagaagtgactcactgtggaacgatgagaaggaaataccgcgtttgtaatgtaacaagaaggcctgcaagtcatcaaacctttcctttacagttagaaaatggccagactgtggagagaacagtagcacagtatttcagagagaaatacaacctccagctgaaataccctcatcttccttgcctacaagtgggacaagaacagaaacacacctacctgcctttagaagtatgtaacattgtagctggccagcggtgtatcaagaagctaacggacaatcagacatcaactatgataaaggccacagcgagatctgctccagatagacaagaggaaataagcagattggtgagaagtgcaaattatgatgcagatccgtttgttcaagagttccagttcaaggtccgtgatgagatggcccatgtgacagggcgcgtgctcccagctccaatgttgcagtatggaggacggaatcgaacagtggcaaccccaagtcatggagtatgggacatgcgagggaagcagtttcacactggtgttgagatcaaaatgtgggctatagcttgctttgcaacgcaaagacaatgcagagaagaaatactgaagggtttcacagaccagctgcgcaagatctccaaagatgcagggatgccgatccaaggccagccctgtttctgtaaatacgcccagggtgcagacagtgtggagcccatgtttcgacacctcaagaacacctattcagggcttcagctcatcattgtcatcctgccagggaaaacaccggtgtatgcggaggtgaagcgtgtgggagatacactgttgggaatggccacacagtgtgttcaagtcaagaatgtcattaaaacatctccacagaccctatcaaatctgtgcctgaagattaatgttaaactaggaggaatcaacaacatccttgtacctcatcaacgaccttctgtgttccagcagccagtgatctttttgggagctgatgtcactcaccctcctgctggagatggaaagaagccttcaatagctgctgttgtaggtagtatggatgctcatccaagccggtactgtgccacggtgagagttcagcgaccccggcaggaaatcatccaagatctagcctccatggtgagagagcttctcatccagttctacaagtcaacacggttcaagcccacacgtatcatcttctacagggacggggtctctgaaggacagtttcgacaggttttgtattacgaactgctagccattagagaagcctgcatcagtttggagaaagattaccagcctggaataacctatattgtggtgcagaagcgacatcatacacgattgttctgtgctgacagaacagaaagggttggacgaagtggcaatattccagctggaacaactgtggatacggatattacacatccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccctcacactatcatgttttgtgggatgataactgttttactgcagatgaacttcagctgctgacttaccagctctgccacacatatgtgcgctgtacacgatcggtttctatacctgcaccagcgtattatgctcatctggtagcattcagagcacgataccatcttgtggacaaagaacatgacagtgctgaaggaagccatgtttcaggacaaagcaatgggagagatccacaggccctcgcgaaggctgtacaaattcaccaagacaccttacgcacgatgtacttcgcttaagtcaataaaatgggagcatactcactgaaaggaagaactgaaaaattaagccacatacaatgtatgttttcagtggggttggtttatggggtgtgcctccgatcatgctgaagttgacactgtgcaggggcgagaggctaacccttaaattgacacaaggaagattgtttacttcatcgaggaacacagcactattatgcaatacgaaaccagccaaccgcttttttggcgcagaagcaccgccatcttttttttttttttttttaatttctcgtagtttaaccctcttatgcctttacctcaagttgctcggcagcacaactatctttgcaaaaaaaaaaaaagttaaaaaattgatggtgtaatttcaaaaaaaaaaaagcaaaccacctttataggaacaatcacaatgattgtttggggagggaagtgtgcaaaaaaaaaaaaaaaaaaaatttaagttttttaccccactgcattgaggaatctttctctcaatattgccatcaagcattcaaatgtgaacatatccaagtacatttgaatgtacagcactaactagaaaaaattgaggaaggggaagatgttttgcacactaatccaataatttgaacataatttagccaactgctgcctttgtgtctttcttcacagctttggagttctcagctccaatagttccctttttaaaagcaaagaagctagtggtattacgtgcaggcagtagtgatccaaactcttcttgctccctggtgaatttactaaagctgctgttttacctagtccaaaagtttcaattgttttctatctggcaagtcaaatatgttgaagcttcacaggagatcagatgtcccaagttttatgggactacatatagtaaacaccagaactgaaactttagagctaaggtctttttggaaaaaagaaaaatgctagtttacttgctgcctctcacaccttaatgtgatttcatatgtatgtgttttttgaagtttagcttccttttgtttcttttatatttattagagtaataataatgctttaatttaattattacagaacatatggtcaacatcaacttttattttttagaaatgtaaccatgtttattttttaaaaactgacaacttgttttgctatcttttagtgcaataagcgttctaaagaaaaactgtgtccattgagctgtactaaagcagtgtttgtaccactaactgtggaagaatggacacctccatgattttaaaaggacaaagtaaaagccttaattttgaaaggaaagttttatagtcagaaggaatcttgaattttccttttttaaatcaaaaatagcaaaaatgcttctagaattctgcaagctttacttgtcactgcagtgttttgatttaacaaaggaattggccatatttttggctttgaaatgtggaggatatttgaattaaatggaaggggttttttattaagatctaagtttttacatgcttagttaaatctatttgacatcagtaaaatgtctggaattaaaagtttttaggcttttttcctctttgataatgactttccttttaaaattaagttattggtaacttcatttcactttgcaaataaagagggctgggatagttctaacatgttaaatcactgaaatgtgaaacaaattaatgggactctttcattccactttaaaggtaagacaatatttaagatgtcagagacgagcatttattcaatgaggggactggggagttttgcactttgtaaactcgtgaactgcatttttgactgtttttatttgcactggttcatagtatatatactgcagatcgtttgtatgggcattgctgttatcccagcccttctgaactccacctgctctccacatgaaaaccagtgggttgatacaagtagcttatctcctgtcattctcatgaaatccgctgtttgccaatatactgtattttgagcctaaaatctgagcccgttttgcttcaacagacgtgaatctcccccattttttctgccagaaaacaaagtactgtattttgtgcatttgtatattgtattgaaatgtatgtagtgctgttcacaacactgtctcaaagagctttactaaaccgttagtgtatatacatattttatctcccaatatcaaggaagataatgtaaaaagactaactttgcaaagctaaaattgcactggaaatagtcgtgacggtgggcagttggctagtggcttgggg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