LOCUS       XM_027937513            3135 bp    mRNA    linear   ROD 21-MAY-2020
DEFINITION  PREDICTED: Marmota flaviventris protein argonaute-3 (LOC114094375),
            mRNA.
ACCESSION   XM_027937513
VERSION     XM_027937513.1
DBLINK      BioProject: PRJNA516936
KEYWORDS    RefSeq.
SOURCE      Marmota flaviventris (yellow-bellied marmot)
  ORGANISM  Marmota flaviventris
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciuromorpha; Sciuridae; Xerinae; Marmotini; Marmota.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_023144676.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Marmota flaviventris Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3135
                     /organism="Marmota flaviventris"
                     /mol_type="mRNA"
                     /isolate="SJ_83"
                     /db_xref="taxon:93162"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..3135
                     /gene="LOC114094375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 mRNAs, 34 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:114094375"
     CDS             272..2854
                     /gene="LOC114094375"
                     /codon_start=1
                     /product="protein argonaute-3"
                     /protein_id="XP_027793314.1"
                     /db_xref="GeneID:114094375"
                     /translation="

MEIGSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    488..772
                     /gene="LOC114094375"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    800..952
                     /gene="LOC114094375"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    953..1315
                     /gene="LOC114094375"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1109..1111,1154..1156,1196..1198,1208..1210,
                     1262..1264,1283..1285,1289..1291)
                     /gene="LOC114094375"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1448..2725
                     /gene="LOC114094375"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1859..1861,1871..1873,1907..1918,1925..1927,
                     1949..1951,1958..1960,1970..1972,1982..1984)
                     /gene="LOC114094375"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2063..2065,2069..2071,2279..2281,2693..2695)
                     /gene="LOC114094375"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gcgtctggggccgccggcgacgcaagttccggacggggctcccttctcctcgcctcacgcctctccttcctctcgcctgatcccgggctgtctcccgaccgcggcccttccggccgagcgccttctgagtgcggtagcggaggggaagccgtcgtcgtccccagcctcggggccgagtgaggtgcctgtcgcgccgcgtcgccccctcgccgactcctcgcccctgtggcgggcgccgttttcgccccaagcactccccccagctccatgaatggaaatcggctccgcaggacctgttggggcccagcccctactcatggtgcccagaagacctggctatggcaccatgggcaaacccattaaactgctggctaactgttttcaagttgagattccaaagattgatgtctacctctatgaggtagatattaaaccagacaaatgtcctaggagagtgaacagggaagtagttgactcaatggttcagcattttaaagtaactatatttggagaccgtagaccagtttatgatggaaaaagaagcctttacacagccaatccacttcctgtggcaactactggggtggatttagatgttactttacctggggaaggtggaaaagatcgacctttcaaggtgtcaatcaaatttgtctctcgcgtgagttggcacctactccatgaagtactgacaggacggaccttgcctgagccactggaattagacaagccaatcagcactaaccctgttcatgccgttgatgtggtgctacgacatctgccctccatgaaatatacgcctgtggggcgttcctttttctcagctccagaaggatatgaccaccctctgggagggggcagggaagtatggtttggattccatcaatctgttcgacctgccatgtggaaaatgatgcttaatatcgatgtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgatattcacaatattgatgaacaaccaagacctctgactgattctcaccgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacaagaaggcctgccagtcatcaaacctttcccttacagctagaaaatggccaaactgtggagagaacagtagctcagtatttcagagaaaagtacactcttcagttgaagtacccacaccttccctgtctgcaagtggggcaggagcagaaacatacctacctgccgctggaagtctgtaatattgtggcaggacaacgatgtattaagaaactaacagacaatcagacttcaactatgatcaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgagatgaaatggcccatgtaaccggacgtgtacttccagcacctatgctccagtatggaggacggaatcggacagtggcaacaccaagccacggagtatgggatatgcgaggaaaacagttccacacaggagttgaaatcaaaatgtgggctatagcttgttttgccacacagaggcagtgcagagaagaaattttaaagggtttcacagaccaactgcgtaagatttccaaggatgcagggatgcccatccagggccagccatgcttctgcaaatacgcacagggcgcagacagcgtagagcccatgttccggcacctcaagaatacatactctgggttacagctcattattgtcatcctgccaggaaagacaccagtgtatgcggaggtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgttcaagtgaagaatgtaataaaaacatctcctcaaactctctcaaatttgtgcctaaagattaatgttaaactcggcgggataaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcatccacctgctggtgatgggaaaaaaccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgccacagtaagagttcagagacccaggcaggagatcatccaggacttggcatccatggtccgagaacttctcattcaattttataagtcaactcggttcaaacctactcgtatcatcttttatcgggatggtgtttcagagggacagtttagacaggtgttatattatgagctactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctatatcgtagtacagaagagacatcacactcgactgttttgtgctgataggacagaaagggtcggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccgtatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactaccatgttttatgggatgataactgctttactgcagatgaacttcagctgctaacttaccagctctgccacacttacgtacgctgtacacgatctgtttctatacctgcaccagcgtattatgctcacctggtagcattcagagccagatatcatcttgtggacaaagaacacgacagtgctgaaggaagccacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaagtccaaggaagaactgaaagatgcgtcgacacaacgtatgttttgaggtctcactgtgtggcccagactggtttcaaactcagaggctcacgtaatcctcccacctgagccttcccagtagctgggactacaggtatgcaccacacctggctgtttttttatattgaagtttcatgaatatagtcaagaacataggaaagaaaagaaaatagtatatcctaaatgtaaaaacttggtttatgcttgcttaatataaataaaaccatcttcctttgtctgtg

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