LOCUS       NM_001007985            1487 bp    mRNA    linear   VRT 24-SEP-2023
DEFINITION  Gallus gallus H6 family homeobox 3 (HMX3), mRNA.
ACCESSION   NM_001007985 XM_426755
VERSION     NM_001007985.2
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 1487)
  AUTHORS   Tang H, Finn RD and Thomas PD.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 1487)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1487)
  AUTHORS   Herbrand H, Guthrie S, Hadrys T, Hoffmann S, Arnold HH,
            Rinkwitz-Brandt S and Bober E.
  TITLE     Two regulatory genes, cNkx5-1 and cPax2, show different responses
            to local signals during otic placode and vesicle formation in the
            chick embryo
  JOURNAL   Development 125 (4), 645-654 (1998)
   PUBMED   9435285
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAENSK010000232.1.
            
            On Nov 18, 2021 this sequence version replaced NM_001007985.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns
                              SAMEA103992323, SAMEA103992428 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-509               JAENSK010000232.1  11500589-11501097
            510-1487            JAENSK010000232.1  11501281-11502258
FEATURES             Location/Qualifiers
     source          1..1487
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="6"
                     /map="6"
     gene            1..1487
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="H6 family homeobox 3"
                     /db_xref="CGNC:16346"
                     /db_xref="GeneID:429199"
     exon            1..509
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             194..1120
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="NK homeobox; homeo box (H6 family) 3; cNkx5-1;
                     homeobox protein Nkx-5.1; homeobox protein H6 family
                     member 3; homeobox (H6 family) 3"
                     /codon_start=1
                     /product="homeobox protein HMX3"
                     /protein_id="NP_001007986.2"
                     /db_xref="CGNC:16346"
                     /db_xref="GeneID:429199"
                     /translation="

MPETGQEPPSAPPPPPPPKESFYIKNLLNGDPPKAAPKQPRALFAPSGKADGSGFALSQVGDLSFPRFEIPAPRFALSAHCLERAQTWWYPYALTPAGAHLPRTEAAEKSLLRDSSPASGTDRDSPEPLLQGGDAEQKERDPKSPAEIVLEESDSEEGKKEGGAEDWKKREESPEKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSGAESSAAGGGGPGPQPLLTFPHPVYYSHPVVTSVPLLRPV"

     misc_feature    194..364
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="propagated from UniProtKB/Swiss-Prot (O57601.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    512..745
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="propagated from UniProtKB/Swiss-Prot (O57601.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    order(737..751,755..757,806..808,824..826,863..865,
                     869..874,881..886,890..898,902..907)
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    743..904
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(743..745,752..754,872..874,881..886,893..895)
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            510..1487
                     /gene="HMX3"
                     /gene_synonym="NKX5-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctctccctccgcctgcccgcggcagcgcccggtgccgcgcggctcccctcggccccccgcgctgccgcccccccatgcgaggggcccccggccgggcccgccgcgctcccccgccgcgccgccgccgcgcctctcccccgcgccgccgggagccgccacccgcggcgggcaggaagcgggcgggcagcggaggatgccggagaccgggcaggagccgcccagcgccccgccgccgccgccccctcccaaggagtccttctacatcaagaacctgctcaacggagacccccccaaagcggcccccaagcagccgagggctctgttcgccccttcgggcaaagcggacggctccggcttcgccctctcgcaggtgggagatctctcctttccccgcttcgagatcccggcgccgcgcttcgctctgagcgcgcactgcctggagcgagcccagacctggtggtacccctacgcgctgacgccggccggagcccacctgccccgcaccgaagccgcggagaaatccctcctgcgggactcgtcccccgcgtcgggcaccgacagggactccccggagccgctgctccaggggggggacgcggaacagaaggagcgggaccccaagagccccgccgagatcgtgctggaggagagcgactcggaggaggggaagaaggagggcggcgcggaggactggaagaagcgggaggagagccccgagaagaagccgtgccgcaagaagaagacgcgcacggtgttcagccgcagccaggtcttccagctcgagtccaccttcgacatgaagcgctacctgagcagctcggagcgggccggcctggccgcttcgctgcacctcacagagacccaggtgaagatctggttccagaaccgccgcaacaagtggaagcggcagctggcggccgagctggaggcggccaacctcagccacgcggccgcgcagcgcatcgtgcgcgtccccatcctctaccacgagaactcgggcgcggagagcagcgcggcgggaggcggcggccccggcccgcagcctctgctcaccttcccccaccccgtttattactcccaccccgtggtcacctccgtaccgctcctgcggcccgtctgagccccgcgcggagcggcgcggagccgcccgtaagtagcgctgcggccctacagccggagccggggagaggggagcggggggggggggggggcaccgggggttaaaggggagggaggtgtgaggagggtaaggaaaggatgaaaaagtgtaacaagaaaataattcgggagcaaaagtggggaagaggggggaaggaaaacgaaagcgggcactgtagggcaccccggggctgtcacacgttttgtaaccgcaaacacacaccgcgatggtctctgtggctttaggtttatttttgtacaaaagaaaaattaaaaaaaaaaaagataataataataataataattaaaaaacaaaaagatcccacgcc

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