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Previous release (v1)
2024-05-01 11:13:44, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NR_039895 90 bp RNA linear PRI 11-SEP-2020
DEFINITION Homo sapiens microRNA 4741 (MIR4741), microRNA.
ACCESSION NR_039895
VERSION NR_039895.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 90)
AUTHORS Enomoto Y, Takagi R, Naito Y, Kiniwa T, Tanaka Y, Hamada-Tsutsumi
S, Kawano M, Matsushita S, Ochiya T and Miyajima A.
TITLE Identification of the novel 3' UTR sequences of human IL-21 mRNA as
potential targets of miRNAs
JOURNAL Sci Rep 7 (1), 7780 (2017)
PUBMED 28798470
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 90)
AUTHORS Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L,
Loman N, Jonsson G, Naya H, Hoglund M, Borg A and Rovira C.
TITLE Identification of new microRNAs in paired normal and tumor breast
tissue suggests a dual role for the ERBB2/Her2 gene
JOURNAL Cancer Res. 71 (1), 78-86 (2011)
PUBMED 21199797
REFERENCE 3 (bases 1 to 90)
AUTHORS Kozomara A and Griffiths-Jones S.
TITLE miRBase: integrating microRNA annotation and deep-sequencing data
JOURNAL Nucleic Acids Res. 39 (Database issue), D152-D157 (2011)
PUBMED 21037258
REFERENCE 4 (bases 1 to 90)
AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright
AJ.
TITLE miRBase: microRNA sequences, targets and gene nomenclature
JOURNAL Nucleic Acids Res. 34 (Database issue), D140-D144 (2006)
PUBMED 16381832
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by NCBI staff in collaboration with miRBase. The reference
sequence was derived from AC091147.15.
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
that are involved in post-transcriptional regulation of gene
expression in multicellular organisms by affecting both the
stability and translation of mRNAs. miRNAs are transcribed by RNA
polymerase II as part of capped and polyadenylated primary
transcripts (pri-miRNAs) that can be either protein-coding or
non-coding. The primary transcript is cleaved by the Drosha
ribonuclease III enzyme to produce an approximately 70-nt stem-loop
precursor miRNA (pre-miRNA), which is further cleaved by the
cytoplasmic Dicer ribonuclease to generate the mature miRNA and
antisense miRNA star (miRNA*) products. The mature miRNA is
incorporated into a RNA-induced silencing complex (RISC), which
recognizes target mRNAs through imperfect base pairing with the
miRNA and most commonly results in translational inhibition or
destabilization of the target mRNA. The RefSeq represents the
predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Sequence Note: This record represents a predicted microRNA
stem-loop as defined by miRBase. Some sequence at the 5' and 3'
ends may not be included in the intermediate precursor miRNA
produced by Drosha cleavage.
##Evidence-Data-START##
Transcript is intronless :: LM611401.1 [ECO:0000345]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-90 AC091147.15 61000-61089 c
FEATURES Location/Qualifiers
source 1..90
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q11.2"
gene 1..90
/gene="MIR4741"
/gene_synonym="mir-4741"
/note="microRNA 4741"
/db_xref="GeneID:100616139"
/db_xref="HGNC:HGNC:41661"
/db_xref="miRBase:MI0017379"
precursor_RNA 1..90
/gene="MIR4741"
/gene_synonym="mir-4741"
/product="microRNA 4741"
/db_xref="GeneID:100616139"
/db_xref="HGNC:HGNC:41661"
/db_xref="miRBase:MI0017379"
exon 1..90
/gene="MIR4741"
/gene_synonym="mir-4741"
/inference="alignment:Splign:2.1.0"
variation 1
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:1910165827"
variation 2..13
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="gggcggggcggg"
/replace="gggcggggcggggcggg"
/db_xref="dbSNP:1340137046"
variation 2
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:918717412"
variation 4
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1910166918"
variation 5
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace=""
/replace="c"
/db_xref="dbSNP:2144370104"
variation 5
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:952898711"
variation 6
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:903566848"
variation 8
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:984165338"
variation 9
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1910168662"
variation 10
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/db_xref="dbSNP:916560238"
variation 12
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1291064627"
variation 13
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1431842941"
variation 14
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="g"
/replace="t"
/db_xref="dbSNP:1310610302"
variation 15..50
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="ccggccgcctccgagcccggccggcagcccccggcc"
/replace="ccggccgcctccgagcccggccggcagcccccggccgcctccgagccc
ggccggcagcccccggcc"
/db_xref="dbSNP:1910169903"
variation 15..39
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="ccggccgcctccgagcccggccggc"
/replace="ccggccgcctccgagcccggccggccgcctccgagcccggccggc"
/db_xref="dbSNP:1910169673"
variation 17
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1910170100"
variation 18
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1387476571"
variation 19
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:564522150"
variation 20
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:948953370"
variation 21..43
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="gcctccgagcccggccggcagcc"
/replace="gcctccgagcccggccggcagcctccgagcccggccggcagcc"
/db_xref="dbSNP:1213061736"
variation 22
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:1910170560"
variation 23..39
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="ctccgagcccggccggc"
/db_xref="dbSNP:1910170836"
variation 24
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1271196832"
variation 25
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1175061423"
variation 26
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:1910172131"
variation 27
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:7244973"
variation 29..42
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="gcccggccggcagc"
/replace="gcccggccggcagcgcccggccggcagc"
/db_xref="dbSNP:1910173144"
variation 29
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:375377861"
variation 31
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:1567941948"
variation 32
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1030734796"
variation 33
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1910173887"
variation 36
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1910174202"
variation 37
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/db_xref="dbSNP:1194050617"
variation 38
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1186893651"
variation 39
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:142828641"
variation 41
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace=""
/replace="g"
/db_xref="dbSNP:1910175239"
variation 41
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:2144370557"
variation 42
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:928143358"
variation 43
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:935473088"
variation 44
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:1232613701"
variation 46
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:886053653"
variation 47
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1298292922"
variation 50
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:886053654"
variation 52
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:1011054605"
variation 53..55
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="aaa"
/replace="aaaa"
/db_xref="dbSNP:1567941990"
variation 54
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:1050116387"
variation 55
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:984770550"
variation 58
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1406343466"
ncRNA 59..81
/ncRNA_class="miRNA"
/gene="MIR4741"
/gene_synonym="mir-4741"
/product="hsa-miR-4741"
/db_xref="miRBase:MIMAT0019871"
/db_xref="GeneID:100616139"
/db_xref="HGNC:HGNC:41661"
/db_xref="miRBase:MI0017379"
variation 60..62
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="g"
/replace="gg"
/replace="ggg"
/db_xref="dbSNP:1301823545"
variation 60
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:559384120"
variation 62
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:886053655"
variation 63
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:7227168"
variation 65
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:115479920"
variation 66
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:561516318"
variation 67
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:993377434"
variation 68
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1027887214"
variation 69
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1380799029"
variation 70
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1910180788"
variation 71
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:952848411"
variation 72..75
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="gggg"
/replace="ggggg"
/db_xref="dbSNP:1482292247"
variation 72
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:530533933"
variation 73
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1910181798"
variation 74
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:916592914"
variation 75
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:550385932"
variation 76
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="g"
/replace="t"
/db_xref="dbSNP:2144371068"
variation 78
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:536665939"
variation 79
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1598628191"
variation 80
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="g"
/db_xref="dbSNP:982330999"
variation 82
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:1910183315"
variation 86
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="c"
/replace="t"
/db_xref="dbSNP:1910183553"
variation 87
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="g"
/db_xref="dbSNP:1910183766"
variation 88
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/db_xref="dbSNP:1910183995"
variation 90
/gene="MIR4741"
/gene_synonym="mir-4741"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:570452407"
ORIGIN
cgggcggggcgggtccggccgcctccgagcccggccggcagcccccggccttaaagcgcgggctgtccggaggggtcggctttcccaccg
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]