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2026-10-05 17:00:39, GGRNA.v2 : RefSeq release 233 (Jan, 2026)

LOCUS       NR_031729                 80 bp    RNA     linear   PRI 14-FEB-2024
DEFINITION  Homo sapiens microRNA 1908 (MIR1908), microRNA.
ACCESSION   NR_031729
VERSION     NR_031729.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 80)
  AUTHORS   Zhou,Y. and Li,W.
  TITLE     Methyltransferase-like 3-mediated m6A modification of miR-1908-5p
            contributes to nasopharyngeal carcinoma progression by targeting
            homeodomain-only protein homeobox
  JOURNAL   Environ Toxicol 39 (3), 1631-1640 (2024)
   PUBMED   38018881
  REMARK    GeneRIF: Methyltransferase-like 3-mediated m6A modification of
            miR-1908-5p contributes to nasopharyngeal carcinoma progression by
            targeting homeodomain-only protein homeobox.
REFERENCE   2  (bases 1 to 80)
  AUTHORS   Soubeyrand,S., Lau,P., Beehler,K., McShane,K. and McPherson,R.
  TITLE     miR1908-5p regulates energy homeostasis in hepatocyte models
  JOURNAL   Sci Rep 11 (1), 23748 (2021)
   PUBMED   34887471
  REMARK    GeneRIF: miR1908-5p regulates energy homeostasis in hepatocyte
            models.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 80)
  AUTHORS   Yoshida,K., Yokoi,A., Matsuzaki,J., Kato,T., Ochiya,T., Kajiyama,H.
            and Yamamoto,Y.
  TITLE     Extracellular microRNA profiling for prognostic prediction in
            patients with high-grade serous ovarian carcinoma
  JOURNAL   Cancer Sci 112 (12), 4977-4986 (2021)
   PUBMED   34618992
  REMARK    GeneRIF: Extracellular microRNA profiling for prognostic prediction
            in patients with high-grade serous ovarian carcinoma.
REFERENCE   4  (bases 1 to 80)
  AUTHORS   Yu,D.S., Song,X.L. and Yan,C.
  TITLE     Oncogenic miRNA-1908 targets HDAC10 and promotes the aggressive
            phenotype of cervical cancer cell
  JOURNAL   Kaohsiung J Med Sci 37 (5), 402-410 (2021)
   PUBMED   33493381
  REMARK    GeneRIF: Oncogenic miRNA-1908 targets HDAC10 and promotes the
            aggressive phenotype of cervical cancer cell.
REFERENCE   5  (bases 1 to 80)
  AUTHORS   Zhu,Y., Wang,Q., Xia,Y., Xiong,X., Weng,S., Ni,H., Ye,Y., Chen,L.,
            Lin,J., Chen,Y., Niu,H., Chen,X. and Lin,Y.
  TITLE     Evaluation of MiR-1908-3p as a novel serum biomarker for breast
            cancer and analysis its oncogenic function and target genes
  JOURNAL   BMC Cancer 20 (1), 644 (2020)
   PUBMED   32650755
  REMARK    GeneRIF: Evaluation of MiR-1908-3p as a novel serum biomarker for
            breast cancer and analysis its oncogenic function and target genes.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 80)
  AUTHORS   Kozomara,A. and Griffiths-Jones,S.
  TITLE     miRBase: integrating microRNA annotation and deep-sequencing data
  JOURNAL   Nucleic Acids Res 39 (Database issue), D152-D157 (2011)
   PUBMED   21037258
REFERENCE   7  (bases 1 to 80)
  AUTHORS   Creighton,C.J., Benham,A.L., Zhu,H., Khan,M.F., Reid,J.G.,
            Nagaraja,A.K., Fountain,M.D., Dziadek,O., Han,D., Ma,L., Kim,J.,
            Hawkins,S.M., Anderson,M.L., Matzuk,M.M. and Gunaratne,P.H.
  TITLE     Discovery of novel microRNAs in female reproductive tract using
            next generation sequencing
  JOURNAL   PLoS One 5 (3), e9637 (2010)
   PUBMED   20224791
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 80)
  AUTHORS   Nygaard,S., Jacobsen,A., Lindow,M., Eriksen,J., Balslev,E.,
            Flyger,H., Tolstrup,N., Moller,S., Krogh,A. and Litman,T.
  TITLE     Identification and analysis of miRNAs in human breast cancer and
            teratoma samples using deep sequencing
  JOURNAL   BMC Med Genomics 2, 35 (2009)
   PUBMED   19508715
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 80)
  AUTHORS   Bar,M., Wyman,S.K., Fritz,B.R., Qi,J., Garg,K.S., Parkin,R.K.,
            Kroh,E.M., Bendoraite,A., Mitchell,P.S., Nelson,A.M., Ruzzo,W.L.,
            Ware,C., Radich,J.P., Gentleman,R., Ruohola-Baker,H. and Tewari,M.
  TITLE     MicroRNA discovery and profiling in human embryonic stem cells by
            deep sequencing of small RNA libraries
  JOURNAL   Stem Cells 26 (10), 2496-2505 (2008)
   PUBMED   18583537
REFERENCE   10 (bases 1 to 80)
  AUTHORS   Griffiths-Jones,S., Grocock,R.J., van Dongen,S., Bateman,A. and
            Enright,A.J.
  TITLE     miRBase: microRNA sequences, targets and gene nomenclature
  JOURNAL   Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
   PUBMED   16381832
COMMENT     PROVISIONAL REFSEQ: This record is based on preliminary annotation
            provided by NCBI staff in collaboration with miRBase. The reference
            sequence was derived from AP002380.3.
            
            Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
            that are involved in post-transcriptional regulation of gene
            expression in multicellular organisms by affecting both the
            stability and translation of mRNAs. miRNAs are transcribed by RNA
            polymerase II as part of capped and polyadenylated primary
            transcripts (pri-miRNAs) that can be either protein-coding or
            non-coding. The primary transcript is cleaved by the Drosha
            ribonuclease III enzyme to produce an approximately 70-nt stem-loop
            precursor miRNA (pre-miRNA), which is further cleaved by the
            cytoplasmic Dicer ribonuclease to generate the mature miRNA and
            antisense miRNA star (miRNA*) products. The mature miRNA is
            incorporated into a RNA-induced silencing complex (RISC), which
            recognizes target mRNAs through imperfect base pairing with the
            miRNA and most commonly results in translational inhibition or
            destabilization of the target mRNA. The RefSeq represents the
            predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
            
            Sequence Note: This record represents a predicted microRNA
            stem-loop as defined by miRBase. Some sequence at the 5' and 3'
            ends may not be included in the intermediate precursor miRNA
            produced by Drosha cleavage.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: LM610376.1 [ECO:0000345]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-80                AP002380.3         136165-136244       c
FEATURES             Location/Qualifiers
     source          1..80
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.2"
     gene            1..80
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /note="microRNA 1908"
                     /db_xref="GeneID:100302263"
                     /db_xref="HGNC:HGNC:35392"
                     /db_xref="miRBase:MI0008329"
     precursor_RNA   1..80
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /product="microRNA 1908"
                     /db_xref="GeneID:100302263"
                     /db_xref="HGNC:HGNC:35392"
                     /db_xref="miRBase:MI0008329"
     exon            1..80
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /inference="alignment:Splign:2.1.0"
     variation       1
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2135942305"
     variation       2
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1481697410"
     variation       3
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2066969747"
     variation       4
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1176536079"
     variation       5
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:174561"
     variation       6
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2541078986"
     variation       7
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1454425320"
     variation       9
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1203639116"
     variation       10
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1208260464"
     variation       11
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2135942274"
     ncRNA           12..32
                     /ncRNA_class="miRNA"
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /product="hsa-miR-1908-5p"
                     /db_xref="miRBase:MIMAT0007881"
                     /db_xref="GeneID:100302263"
                     /db_xref="HGNC:HGNC:35392"
                     /db_xref="miRBase:MI0008329"
     variation       12
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2066969394"
     variation       13
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2066969350"
     variation       14
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2541078970"
     variation       15
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1042356928"
     variation       16..19
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:750758515"
     variation       16
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1172531430"
     variation       20
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1004964674"
     variation       24
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2050637164"
     variation       26
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1412162872"
     variation       29
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2066969093"
     variation       33
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:546582324"
     variation       34
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:915177576"
     variation       35..37
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="tat"
                     /replace="tatat"
                     /db_xref="dbSNP:1372050947"
     variation       35
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:2066968945"
     variation       36
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2066968906"
     variation       38
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2066968808"
     variation       39
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2066968772"
     variation       48
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1591156264"
     ncRNA           49..69
                     /ncRNA_class="miRNA"
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /product="hsa-miR-1908-3p"
                     /db_xref="miRBase:MIMAT0026916"
                     /db_xref="GeneID:100302263"
                     /db_xref="HGNC:HGNC:35392"
                     /db_xref="miRBase:MI0008329"
     variation       50
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2066968688"
     variation       51
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2135942218"
     variation       54
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:533201588"
     variation       55
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1301364574"
     variation       56
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2066968500"
     variation       58..59
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="g"
                     /replace="gg"
                     /db_xref="dbSNP:1341507721"
     variation       58
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2066968458"
     variation       64
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:564195861"
     variation       65..68
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="ccc"
                     /replace="cccc"
                     /db_xref="dbSNP:2541078907"
     variation       67
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1273704718"
     variation       68
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2066968260"
     variation       69
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:878892659"
     variation       70
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1306845828"
     variation       71..75
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="cccc"
                     /replace="ccccc"
                     /db_xref="dbSNP:1274792263"
     variation       71
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1314769794"
     variation       75
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:778143378"
     variation       77
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2541078891"
     variation       79
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2066967976"
     variation       80
                     /gene="MIR1908"
                     /gene_synonym="hsa-mir-1908; mir-1908; MIRN1908"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2066967936"
ORIGIN      
cgggaatgccgcggcggggacggcgattggtccgtatgtgtggtgccaccggccgccggctccgccccggcccccgcccc
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]