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Previous release (v1)
2026-10-05 17:00:38, GGRNA.v2 : RefSeq release 233 (Jan, 2026)
LOCUS NR_031638 86 bp RNA linear PRI 06-FEB-2024
DEFINITION Homo sapiens microRNA 1303 (MIR1303), microRNA.
ACCESSION NR_031638
VERSION NR_031638.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 86)
AUTHORS Wang,Y., Li,Z., He,J., Chen,W., Li,Y., Chen,X., Liang,J., Yu,Q. and
Zhou,J.
TITLE hsa_circ_0002980 prevents proliferation, migration, invasion, and
epithelial-mesenchymal transition of liver cancer cells through
microRNA-1303/cell adhesion molecule 2 axis
JOURNAL Aging (Albany NY) 15 (24), 14915-14929 (2023)
PUBMED 38126999
REMARK GeneRIF: hsa_circ_0002980 prevents proliferation, migration,
invasion, and epithelial-mesenchymal transition of liver cancer
cells through microRNA-1303/cell adhesion molecule 2 axis.
REFERENCE 2 (bases 1 to 86)
AUTHORS Lin,Y., Dai,H., Yu,G., Song,C., Liu,J. and Xu,J.
TITLE Inhibiting KCNMA1-AS1 promotes osteogenic differentiation of HBMSCs
via miR-1303/cochlin axis
JOURNAL J Orthop Surg Res 18 (1), 73 (2023)
PUBMED 36717952
REMARK GeneRIF: Inhibiting KCNMA1-AS1 promotes osteogenic differentiation
of HBMSCs via miR-1303/cochlin axis.
Publication Status: Online-Only
REFERENCE 3 (bases 1 to 86)
AUTHORS Trang,N.T.N., Lai,C.Y., Tsai,H.C., Huang,Y.L., Liu,S.C., Tsai,C.H.,
Fong,Y.C., Tzeng,H.E. and Tang,C.H.
TITLE Apelin promotes osteosarcoma metastasis by upregulating PLOD2
expression via the Hippo signaling pathway and
hsa_circ_0000004/miR-1303 axis
JOURNAL Int J Biol Sci 19 (2), 412-425 (2023)
PUBMED 36632453
REMARK GeneRIF: Apelin promotes osteosarcoma metastasis by upregulating
PLOD2 expression via the Hippo signaling pathway and
hsa_circ_0000004/miR-1303 axis.
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 86)
AUTHORS Chen,Y.C., Hsiao,C.C., Wu,C.C., Chao,T.Y., Leung,S.Y., Chang,Y.P.,
Tseng,C.C., Lee,C.P., Hsu,P.Y., Wang,T.Y., Wang,P.W., Chen,T.W. and
Lin,M.C.
TITLE Next generation sequencing reveals miR-431-3p/miR-1303 as
immune-regulating microRNAs for active tuberculosis
JOURNAL J Infect 85 (5), 519-533 (2022)
PUBMED 36057384
REMARK GeneRIF: Next generation sequencing reveals miR-431-3p/miR-1303 as
immune-regulating microRNAs for active tuberculosis.
REFERENCE 5 (bases 1 to 86)
AUTHORS Huang,J., Xi,Q., Xiong,J., Peng,H., Yang,H., Sun,Y.U. and
Hoffman,R.M.
TITLE Micro RNA miR-1303 Promotion of Proliferation, Migration and
Invasion of Human Liver Cancer Cells Is Enhanced by Low Talin 1
(TLN1) Expression
JOURNAL Anticancer Res 42 (10), 4715-4725 (2022)
PUBMED 36192016
REMARK GeneRIF: Micro RNA miR-1303 Promotion of Proliferation, Migration
and Invasion of Human Liver Cancer Cells Is Enhanced by Low Talin 1
(TLN1) Expression.
REFERENCE 6 (bases 1 to 86)
AUTHORS Wang,C., Wan,S., Yang,T., Niu,D., Zhang,A., Yang,C., Cai,J., Wu,J.,
Song,J., Zhang,C.Y., Zhang,C. and Wang,J.
TITLE Increased serum microRNAs are closely associated with the presence
of microvascular complications in type 2 diabetes mellitus
JOURNAL Sci Rep 6, 20032 (2016)
PUBMED 26831044
REMARK GeneRIF: Five miRNAs were significantly upregulated in type 2
diabetes mellitus patients (p < 0.05) including miR-661, miR-571,
miR-770-5p, miR-892b and miR-1303. Moreover, the levels of the five
miRNAs were higher in patients with complications than in those
without complications.
Publication Status: Online-Only
REFERENCE 7 (bases 1 to 86)
AUTHORS Zhang,S.J., Feng,J.F., Wang,L., Guo,W., Du,Y.W., Ming,L. and
Zhao,G.Q.
TITLE miR-1303 targets claudin-18 gene to modulate proliferation and
invasion of gastric cancer cells
JOURNAL Dig Dis Sci 59 (8), 1754-1763 (2014)
PUBMED 24647998
REMARK GeneRIF: Downregulation of miR-1303 can inhibit proliferation,
migration and invasion of gastric cancer cells by targeting CLDN18.
REFERENCE 8 (bases 1 to 86)
AUTHORS Ayaz,L., Gorur,A., Yaroglu,H.Y., Ozcan,C. and Tamer,L.
TITLE Differential expression of microRNAs in plasma of patients with
laryngeal squamous cell carcinoma: potential early-detection
markers for laryngeal squamous cell carcinoma
JOURNAL J Cancer Res Clin Oncol 139 (9), 1499-1506 (2013)
PUBMED 23817697
REMARK GeneRIF: High miR-1303 is associated with laryngeal squamous cell
carcinoma.
REFERENCE 9 (bases 1 to 86)
AUTHORS Morin,R.D., O'Connor,M.D., Griffith,M., Kuchenbauer,F., Delaney,A.,
Prabhu,A.L., Zhao,Y., McDonald,H., Zeng,T., Hirst,M., Eaves,C.J.
and Marra,M.A.
TITLE Application of massively parallel sequencing to microRNA profiling
and discovery in human embryonic stem cells
JOURNAL Genome Res 18 (4), 610-621 (2008)
PUBMED 18285502
REMARK Erratum:[Genome Res. 2009 May;19(5):958]
REFERENCE 10 (bases 1 to 86)
AUTHORS Griffiths-Jones,S., Grocock,R.J., van Dongen,S., Bateman,A. and
Enright,A.J.
TITLE miRBase: microRNA sequences, targets and gene nomenclature
JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
PUBMED 16381832
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by NCBI staff in collaboration with miRBase. The reference
sequence was derived from AC008379.7.
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
that are involved in post-transcriptional regulation of gene
expression in multicellular organisms by affecting both the
stability and translation of mRNAs. miRNAs are transcribed by RNA
polymerase II as part of capped and polyadenylated primary
transcripts (pri-miRNAs) that can be either protein-coding or
non-coding. The primary transcript is cleaved by the Drosha
ribonuclease III enzyme to produce an approximately 70-nt stem-loop
precursor miRNA (pre-miRNA), which is further cleaved by the
cytoplasmic Dicer ribonuclease to generate the mature miRNA and
antisense miRNA star (miRNA*) products. The mature miRNA is
incorporated into a RNA-induced silencing complex (RISC), which
recognizes target mRNAs through imperfect base pairing with the
miRNA and most commonly results in translational inhibition or
destabilization of the target mRNA. The RefSeq represents the
predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Sequence Note: This record represents a predicted microRNA
stem-loop as defined by miRBase. Some sequence at the 5' and 3'
ends may not be included in the intermediate precursor miRNA
produced by Drosha cleavage.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-86 AC008379.7 42235-42320
FEATURES Location/Qualifiers
source 1..86
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q33.2"
gene 1..86
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/note="microRNA 1303"
/db_xref="GeneID:100302284"
/db_xref="HGNC:HGNC:35301"
/db_xref="miRBase:MI0006370"
precursor_RNA 1..86
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/product="microRNA 1303"
/db_xref="GeneID:100302284"
/db_xref="HGNC:HGNC:35301"
/db_xref="miRBase:MI0006370"
exon 1..86
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/inference="alignment:Splign:2.1.0"
variation 2
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:1374494305"
variation 3
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1225882950"
variation 5
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:1753907257"
variation 6
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:1305096287"
variation 7
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="g"
/db_xref="dbSNP:781707336"
variation 8
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1391181307"
variation 11
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1365178596"
variation 12
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:142414368"
variation 13
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:77055126"
variation 14
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:2113175831"
variation 16
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:778059978"
variation 17
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:749521848"
variation 18
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="a"
/db_xref="dbSNP:1753908498"
variation 19
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:562358768"
variation 23
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:1371417392"
variation 24
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1480822096"
variation 25
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:1178766263"
variation 26
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1405556402"
variation 30
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:774355328"
variation 32
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1561524504"
variation 33..34
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="t"
/db_xref="dbSNP:2479878097"
variation 33..34
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="aa"
/db_xref="dbSNP:2479878093"
variation 33
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:75378399"
variation 34
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1561524508"
variation 35..47
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="ttttttttttt"
/replace="tttttttttttt"
/replace="ttttttttttttt"
/replace="tttttttttttttt"
/replace="ttttttttttttttt"
/db_xref="dbSNP:rs199839137"
variation 35
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:1211336463"
variation 36
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:745942187"
variation 37..54
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="tttt"
/replace="tttttttttttaaatttt"
/db_xref="dbSNP:777758653"
variation 37
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:768518469"
variation 39
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:2479878132"
variation 40
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:776743647"
variation 43
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:1192344464"
variation 45..48
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="ttta"
/db_xref="dbSNP:1459475936"
variation 46..48
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="tta"
/db_xref="dbSNP:747084698"
variation 47..48
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="ta"
/db_xref="dbSNP:200868230"
variation 47
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:761793925"
variation 48..50
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="aaa"
/db_xref="dbSNP:1561524563"
variation 48..50
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="aa"
/replace="aaa"
/db_xref="dbSNP:33982250"
variation 48
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:75538180"
variation 49
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1266852503"
variation 50..51
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace=""
/replace="at"
/db_xref="dbSNP:746277355"
variation 50
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:201841642"
ncRNA 52..73
/ncRNA_class="miRNA"
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/product="hsa-miR-1303"
/db_xref="miRBase:MIMAT0005891"
/db_xref="GeneID:100302284"
/db_xref="HGNC:HGNC:35301"
/db_xref="miRBase:MI0006370"
variation 53
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:2479878192"
variation 56
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:1753912592"
variation 57
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:370437195"
variation 58
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="g"
/db_xref="dbSNP:1195001383"
variation 59
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:546614687"
variation 60
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:762579883"
variation 61
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:766041486"
variation 63
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:751079975"
variation 64
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:888516744"
variation 65
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="t"
/db_xref="dbSNP:566454487"
variation 66
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:766973220"
variation 68
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1474274822"
variation 69
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:753222192"
variation 70
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1230907999"
variation 73
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:756552638"
variation 74
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:2113176557"
variation 76
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1188215972"
variation 77
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="g"
/replace="t"
/db_xref="dbSNP:1259241548"
variation 78
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1473921471"
variation 82
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="a"
/replace="g"
/db_xref="dbSNP:778111111"
variation 86
/gene="MIR1303"
/gene_synonym="hsa-mir-1303; MIRN1303"
/replace="c"
/replace="t"
/db_xref="dbSNP:1369265562"
ORIGIN
ggctgggcaacatagcgagacctcaactctacaatttttttttttttaaattttagagacggggtcttgctctgttgccaggcttt
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]