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2024-05-01 12:14:10, GGRNA.v2 : RefSeq release 222 (Jan, 2024)

LOCUS       NR_031607                 85 bp    RNA     linear   PRI 15-FEB-2021
DEFINITION  Homo sapiens microRNA 1203 (MIR1203), microRNA.
ACCESSION   NR_031607
VERSION     NR_031607.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 85)
  AUTHORS   Luo T, Yan L and Liu H.
  TITLE     LINC00632 inhibits the malignant development of non-small cell lung
            cancer by downregulating miR-1203
  JOURNAL   J BUON 25 (3), 1517-1524 (2020)
   PUBMED   32862599
  REMARK    GeneRIF: LINC00632 inhibits the malignant development of non-small
            cell lung cancer by downregulating miR-1203.
REFERENCE   2  (bases 1 to 85)
  AUTHORS   Shi J, Li X, Hu Y, Zhang F, Lv X, Zhang X, Chen Q and Hu S.
  TITLE     MiR-1203 is involved in hepatocellular carcinoma metastases and
            indicates a poor prognosis
  JOURNAL   Neoplasma 67 (2), 267-276 (2020)
   PUBMED   31847527
  REMARK    GeneRIF: MiR-1203 is involved in hepatocellular carcinoma
            metastases and indicates a poor prognosis.
REFERENCE   3  (bases 1 to 85)
  AUTHORS   Xu HB, Zheng YF, Wu D, Li Y, Zhou LN and Chen YG.
  TITLE     microRNA-1203 targets and silences cyclophilin D to protect human
            endometrial cells from oxygen and glucose
            deprivation-re-oxygenation
  JOURNAL   Aging (Albany NY) 12 (3), 3010-3024 (2020)
   PUBMED   32041924
  REMARK    GeneRIF: microRNA-1203 targets and silences cyclophilin D to
            protect human endometrial cells from oxygen and glucose
            deprivation-re-oxygenation.
REFERENCE   4  (bases 1 to 85)
  AUTHORS   Enomoto Y, Takagi R, Naito Y, Kiniwa T, Tanaka Y, Hamada-Tsutsumi
            S, Kawano M, Matsushita S, Ochiya T and Miyajima A.
  TITLE     Identification of the novel 3' UTR sequences of human IL-21 mRNA as
            potential targets of miRNAs
  JOURNAL   Sci Rep 7 (1), 7780 (2017)
   PUBMED   28798470
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 85)
  AUTHORS   Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch
            O, Rovira C, Naya H, Dighiero G and Cayota A.
  TITLE     Small RNAs analysis in CLL reveals a deregulation of miRNA
            expression and novel miRNA candidates of putative relevance in CLL
            pathogenesis
  JOURNAL   Leukemia 22 (2), 330-338 (2008)
   PUBMED   17989717
REFERENCE   6  (bases 1 to 85)
  AUTHORS   Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright
            AJ.
  TITLE     miRBase: microRNA sequences, targets and gene nomenclature
  JOURNAL   Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
   PUBMED   16381832
COMMENT     PROVISIONAL REFSEQ: This record is based on preliminary annotation
            provided by NCBI staff in collaboration with miRBase. The reference
            sequence was derived from AC006468.10.
            
            Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
            that are involved in post-transcriptional regulation of gene
            expression in multicellular organisms by affecting both the
            stability and translation of mRNAs. miRNAs are transcribed by RNA
            polymerase II as part of capped and polyadenylated primary
            transcripts (pri-miRNAs) that can be either protein-coding or
            non-coding. The primary transcript is cleaved by the Drosha
            ribonuclease III enzyme to produce an approximately 70-nt stem-loop
            precursor miRNA (pre-miRNA), which is further cleaved by the
            cytoplasmic Dicer ribonuclease to generate the mature miRNA and
            antisense miRNA star (miRNA*) products. The mature miRNA is
            incorporated into a RNA-induced silencing complex (RISC), which
            recognizes target mRNAs through imperfect base pairing with the
            miRNA and most commonly results in translational inhibition or
            destabilization of the target mRNA. The RefSeq represents the
            predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
            
            Sequence Note: This record represents a predicted microRNA
            stem-loop as defined by miRBase. Some sequence at the 5' and 3'
            ends may not be included in the intermediate precursor miRNA
            produced by Drosha cleavage.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                AC006468.10        24703-24787
FEATURES             Location/Qualifiers
     source          1..85
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.32"
     gene            1..85
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /note="microRNA 1203"
                     /db_xref="GeneID:100302211"
                     /db_xref="HGNC:HGNC:35269"
                     /db_xref="miRBase:MI0006335"
     precursor_RNA   1..85
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /product="microRNA 1203"
                     /db_xref="GeneID:100302211"
                     /db_xref="HGNC:HGNC:35269"
                     /db_xref="miRBase:MI0006335"
     exon            1..85
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /inference="alignment:Splign:2.1.0"
     variation       1
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1598375873"
     variation       2
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1212885775"
     variation       3
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:924393341"
     variation       4
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1598375862"
     variation       5
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1364121351"
     ncRNA           6..26
                     /ncRNA_class="miRNA"
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /product="hsa-miR-1203"
                     /db_xref="miRBase:MIMAT0005866"
                     /db_xref="GeneID:100302211"
                     /db_xref="HGNC:HGNC:35269"
                     /db_xref="miRBase:MI0006335"
     variation       8
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:547972348"
     variation       9..10
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="g"
                     /replace="gg"
                     /db_xref="dbSNP:745577400"
     variation       9
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:764824939"
     variation       10
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063979583"
     variation       11
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2143212940"
     variation       12
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:995110609"
     variation       17
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1231461203"
     variation       18
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1338531929"
     variation       20
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1439248445"
     variation       23
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:759274065"
     variation       26
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1399107302"
     variation       29
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1397225938"
     variation       31
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:370132472"
     variation       32
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:971148331"
     variation       33
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:770750211"
     variation       34
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2143212576"
     variation       36
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:760600373"
     variation       37
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2143212502"
     variation       38
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063978984"
     variation       39
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:773079400"
     variation       41
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:772132659"
     variation       43
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1185828122"
     variation       46
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1461993785"
     variation       48
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377012273"
     variation       49
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779157281"
     variation       50
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1598375745"
     variation       52
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:769023712"
     variation       55
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1273851060"
     variation       56
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1567796918"
     variation       59
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:749572635"
     variation       65
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:780536735"
     variation       68
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117091718"
     variation       69
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2063978303"
     variation       74
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:750931820"
     variation       75
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:781566509"
     variation       76
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1296220394"
     variation       78
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:757861784"
     variation       79
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373807500"
     variation       80
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1598375672"
     variation       81
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1332949319"
     variation       82
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:752166614"
     variation       83
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368862137"
     variation       84
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:764848039"
     variation       85
                     /gene="MIR1203"
                     /gene_synonym="hsa-mir-1203; MIRN1203"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1383931148"
ORIGIN      
tcctccccggagccaggatgcagctcaagccacagcagggtgtttagcgctcttcagtggctccagattgtggcgctggtgcagg
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]