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Previous release (v1)
2024-05-01 12:14:02, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NR_030232 127 bp RNA linear PRI 25-SEP-2022
DEFINITION Homo sapiens microRNA 513a-2 (MIR513A2), microRNA.
ACCESSION NR_030232
VERSION NR_030232.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 127)
AUTHORS Li X, Zhang Y, Wang N, Yuan Z, Chen X, Chen Q, Deng H, Tong X, Chen
H, Duan Y and Wei Y.
TITLE CircRNA.0007127 triggers apoptosis through the miR-513a-5p/CASP8
axis in K-562 cells
JOURNAL J Zhejiang Univ Sci B 23 (9), 732-746 (2022)
PUBMED 36111570
REMARK GeneRIF: CircRNA.0007127 triggers apoptosis through the
miR-513a-5p/CASP8 axis in K-562 cells.
REFERENCE 2 (bases 1 to 127)
AUTHORS Wang Y, Cao B, Zhao R, Li H, Wei B and Dai G.
TITLE Knockdown of circBFAR inhibits proliferation and glycolysis in
gastric cancer by sponging miR-513a-3p/hexokinase 2 axis
JOURNAL Biochem Biophys Res Commun 560, 80-86 (2021)
PUBMED 33979737
REMARK GeneRIF: Knockdown of circBFAR inhibits proliferation and
glycolysis in gastric cancer by sponging miR-513a-3p/hexokinase 2
axis.
REFERENCE 3 (bases 1 to 127)
AUTHORS Zhao JL, Zhao LL, Niu WZ, Ding XC and Zhang WL.
TITLE [Deleted in lymphocytic leukemia 1 promoted proliferation and
apoptosis of nephroblastoma cells through regulating miR-513a-5p
and RANBP2 pathway]
JOURNAL Zhonghua Zhong Liu Za Zhi 42 (10), 849-855 (2020)
PUBMED 33113626
REMARK GeneRIF: [Deleted in lymphocytic leukemia 1 promoted proliferation
and apoptosis of nephroblastoma cells through regulating
miR-513a-5p and RANBP2 pathway].
REFERENCE 4 (bases 1 to 127)
AUTHORS Li J, Huang C, Zou Y, Yu J and Gui Y.
TITLE Circular RNA MYLK promotes tumour growth and metastasis via
modulating miR-513a-5p/VEGFC signalling in renal cell carcinoma
JOURNAL J Cell Mol Med 24 (12), 6609-6621 (2020)
PUBMED 32342645
REMARK GeneRIF: Circular RNA MYLK promotes tumour growth and metastasis
via modulating miR-513a-5p/VEGFC signalling in renal cell
carcinoma.
REFERENCE 5 (bases 1 to 127)
AUTHORS Enomoto Y, Takagi R, Naito Y, Kiniwa T, Tanaka Y, Hamada-Tsutsumi
S, Kawano M, Matsushita S, Ochiya T and Miyajima A.
TITLE Identification of the novel 3' UTR sequences of human IL-21 mRNA as
potential targets of miRNAs
JOURNAL Sci Rep 7 (1), 7780 (2017)
PUBMED 28798470
REMARK Publication Status: Online-Only
REFERENCE 6 (bases 1 to 127)
AUTHORS Troppmann B, Kossack N, Nordhoff V, Schuring AN and Gromoll J.
TITLE MicroRNA miR-513a-3p acts as a co-regulator of luteinizing
hormone/chorionic gonadotropin receptor gene expression in human
granulosa cells
JOURNAL Mol Cell Endocrinol 390 (1-2), 65-72 (2014)
PUBMED 24747085
REMARK GeneRIF: miR-513a-3p is involved in the control of the LHCGR
expression by an inversely regulated mechanism at the
post-transcriptional level.
REFERENCE 7 (bases 1 to 127)
AUTHORS Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A,
Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND,
Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U,
Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien
M, Weir DB, Choksi R, De Vita G, Frezzetti D, Trompeter HI, Hornung
V, Teng G, Hartmann G, Palkovits M, Di Lauro R, Wernet P, Macino G,
Rogler CE, Nagle JW, Ju J, Papavasiliou FN, Benzing T, Lichter P,
Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo JJ, Sander C,
Zavolan M and Tuschl T.
TITLE A mammalian microRNA expression atlas based on small RNA library
sequencing
JOURNAL Cell 129 (7), 1401-1414 (2007)
PUBMED 17604727
REFERENCE 8 (bases 1 to 127)
AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright
AJ.
TITLE miRBase: microRNA sequences, targets and gene nomenclature
JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
PUBMED 16381832
REFERENCE 9 (bases 1 to 127)
AUTHORS Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O,
Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y and
Bentwich Z.
TITLE Identification of hundreds of conserved and nonconserved human
microRNAs
JOURNAL Nat Genet 37 (7), 766-770 (2005)
PUBMED 15965474
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by NCBI staff in collaboration with miRBase. The reference
sequence was derived from AL589669.11.
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
that are involved in post-transcriptional regulation of gene
expression in multicellular organisms by affecting both the
stability and translation of mRNAs. miRNAs are transcribed by RNA
polymerase II as part of capped and polyadenylated primary
transcripts (pri-miRNAs) that can be either protein-coding or
non-coding. The primary transcript is cleaved by the Drosha
ribonuclease III enzyme to produce an approximately 70-nt stem-loop
precursor miRNA (pre-miRNA), which is further cleaved by the
cytoplasmic Dicer ribonuclease to generate the mature miRNA and
antisense miRNA star (miRNA*) products. The mature miRNA is
incorporated into a RNA-induced silencing complex (RISC), which
recognizes target mRNAs through imperfect base pairing with the
miRNA and most commonly results in translational inhibition or
destabilization of the target mRNA. The RefSeq represents the
predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Sequence Note: This record represents a predicted microRNA
stem-loop as defined by miRBase. Some sequence at the 5' and 3'
ends may not be included in the intermediate precursor miRNA
produced by Drosha cleavage.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-127 AL589669.11 114287-114413 c
FEATURES Location/Qualifiers
source 1..127
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq27.3"
gene 1..127
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/note="microRNA 513a-2"
/db_xref="GeneID:574510"
/db_xref="HGNC:HGNC:32142"
/db_xref="miRBase:MI0003192"
precursor_RNA 1..127
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/product="microRNA 513a-2"
/db_xref="GeneID:574510"
/db_xref="HGNC:HGNC:32142"
/db_xref="miRBase:MI0003192"
exon 1..127
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/inference="alignment:Splign:2.1.0"
variation 1
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1557100192"
variation 2
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:782327209"
variation 3
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="t"
/db_xref="dbSNP:1557100191"
variation 7
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2015989817"
variation 8
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377537170"
variation 9..23
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="cattcag"
/replace="cattcagccattcag"
/db_xref="dbSNP:782578425"
variation 10
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="t"
/db_xref="dbSNP:2015989679"
variation 11
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1557100190"
variation 13
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:782028037"
variation 14
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:782396876"
variation 17..29
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="cattcagtgtgca"
/replace="cattcagtgtgcattcagtgtgca"
/db_xref="dbSNP:782307168"
variation 20
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373052953"
variation 21..32
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="cagtg"
/replace="cagtgtgcagtg"
/db_xref="dbSNP:1557100175"
variation 22
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:111970838"
variation 24
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:925239760"
variation 25
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:782614546"
variation 26
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1557100180"
variation 27
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:979447762"
variation 28..34
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="cagtgcc"
/db_xref="dbSNP:782294397"
variation 28
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:782487623"
variation 30
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1569536653"
variation 33..36
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="cctt"
/replace="ccttcctt"
/db_xref="dbSNP:782669807"
variation 34
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:782204335"
variation 35
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1362846785"
ncRNA 36..53
/ncRNA_class="miRNA"
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/product="hsa-miR-513a-5p"
/db_xref="miRBase:MIMAT0002877"
/db_xref="GeneID:574510"
/db_xref="HGNC:HGNC:32142"
/db_xref="miRBase:MI0003192"
variation 38
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/db_xref="dbSNP:1557100170"
variation 43
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:782577003"
variation 46
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:782552773"
variation 48
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1557100166"
variation 50
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369895206"
variation 51
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="g"
/db_xref="dbSNP:782795793"
variation 53
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="g"
/replace="t"
/db_xref="dbSNP:2015988062"
variation 57
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:193181398"
variation 58
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="g"
/replace="t"
/db_xref="dbSNP:2124342773"
variation 60
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:372214863"
variation 63
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1557100160"
variation 65
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368775756"
variation 67..70
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="aata"
/replace="aataata"
/db_xref="dbSNP:2015987694"
ncRNA 71..93
/ncRNA_class="miRNA"
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/product="hsa-miR-513a-3p"
/db_xref="miRBase:MIMAT0004777"
/db_xref="GeneID:574510"
/db_xref="HGNC:HGNC:32142"
/db_xref="miRBase:MI0003192"
variation 71
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="g"
/replace="t"
/db_xref="dbSNP:1376206275"
variation 76
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="g"
/replace="t"
/db_xref="dbSNP:1240793492"
variation 81
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1557100149"
variation 85
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="g"
/db_xref="dbSNP:782066339"
variation 93
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1557100144"
variation 94..101
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="gtaatgta"
/replace="gtaatgtaatgta"
/db_xref="dbSNP:2015987041"
variation 94
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="g"
/db_xref="dbSNP:2015987321"
variation 96
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376408446"
variation 97
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1557100142"
variation 99
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2015987108"
variation 103
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/db_xref="dbSNP:965184900"
variation 104
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:782806082"
variation 105
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/db_xref="dbSNP:782143012"
variation 107
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="g"
/replace="t"
/db_xref="dbSNP:1557100137"
variation 108
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:781994871"
variation 109
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="c"
/db_xref="dbSNP:1603229462"
variation 111
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="g"
/db_xref="dbSNP:2015986584"
variation 114
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2015986510"
variation 115
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1319767773"
variation 117
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2015986371"
variation 119
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="c"
/replace="g"
/db_xref="dbSNP:782374243"
variation 123
/gene="MIR513A2"
/gene_synonym="hsa-mir-513a-2; MIRN513-2; MIRN513A-2;
MIRN513A2"
/replace="g"
/replace="t"
/db_xref="dbSNP:2124342645"
ORIGIN
ggatgccacattcagccattcagtgtgcagtgcctttcacagggaggtgtcatttatgtgaactaaaatataaatttcacctttctgagaagggtaatgtacagcatgcactgcatatgtggtgtcc
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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