LOCUS       NM_204619               2757 bp    mRNA    linear   VRT 25-NOV-2024
DEFINITION  Gallus gallus homeobox A11 (HOXA11), mRNA.
ACCESSION   NM_204619
VERSION     NM_204619.2
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 2757)
  AUTHORS   Tang,H., Finn,R.D. and Thomas,P.D.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 2757)
  AUTHORS   Burge,S., Kelly,E., Lonsdale,D., Mutowo-Muellenet,P., McAnulla,C.,
            Mitchell,A., Sangrador-Vegas,A., Yong,S.Y., Mulder,N. and Hunter,S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2757)
  AUTHORS   Yamamoto,M. and Kuroiwa,A.
  TITLE     Hoxa-11 and Hoxa-13 are involved in repression of MyoD during limb
            muscle development
  JOURNAL   Dev Growth Differ 45 (5-6), 485-498 (2003)
   PUBMED   14706073
  REMARK    GeneRIF: Hoxa-11 and Hoxa-13 are involved in the negative
            regulation of MyoD expression in limb muscle precursors
REFERENCE   4  (bases 1 to 2757)
  AUTHORS   Rogina,B., Coelho,C.N., Kosher,R.A. and Upholt,W.B.
  TITLE     The pattern of expression of the chicken homolog of HOX1I in the
            developing limb suggests a possible role in the ectodermal
            inhibition of chondrogenesis
  JOURNAL   Dev Dyn 193 (1), 92-101 (1992)
   PUBMED   1347239
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAENSK010000037.1.
            
            On Sep 23, 2021 this sequence version replaced NM_204619.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M81250.1, JF317540.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA103992415, SAMEA103992428
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-724               JAENSK010000037.1  1596260-1596983     c
            725-2757            JAENSK010000037.1  1592886-1594918     c
FEATURES             Location/Qualifiers
     source          1..2757
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="2"
                     /map="2"
     gene            1..2757
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /note="homeobox A11"
                     /db_xref="CGNC:49268"
                     /db_xref="GeneID:395327"
     exon            1..724
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    37..39
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /note="upstream in-frame stop codon"
     CDS             64..957
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /note="homeodomain-containing protein; homeo box A11;
                     homeobox protein Hox-1.9"
                     /codon_start=1
                     /product="homeobox protein Hox-A11"
                     /protein_id="NP_989950.1"
                     /db_xref="CGNC:49268"
                     /db_xref="GeneID:395327"
                     /translation="

MMDFDERVPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIDPSSKWHPRNNLPHCYSAEEIMHRDCLPSTTTASMGEVFGKSTANVYHHPSANVSSNFYSTVGRNGVLPQAFDQFFETAYGTAENPSSADYPPDKSGEKAPAAAGATAATSSSEGGCGGAAAAAGKERRRRPESGSSPESSSGNNEEKSGSSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL"

     misc_feature    139..522
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /note="Protein of unknown function (DUF3528); Region:
                     DUF3528; pfam12045"
                     /db_xref="CDD:432284"
     misc_feature    514..753
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /note="propagated from UniProtKB/Swiss-Prot (P31258.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    739..909
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            725..2757
                     /gene="HOXA11"
                     /gene_synonym="chox-1.9; ghox-1I; GHOX1I; HOX1I"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggggcagctgcgctagagaatcatgttaagctcagctaatgcggagaagccgaggtagccctaatgatggattttgatgagcgtgttccttgttcctctaacatgtatttgccaagttgtacgtactacgtctcgggtcctgatttctccagcctcccttcttttctgccccagaccccgtcttctcgccctatgacatactcctactcctccaacctgccccaggtccaacccgtgagagaagtgaccttcagggaatatgccattgatccctccagtaaatggcacccccggaacaacctgccccactgctactccgcagaggagatcatgcacagagactgcttgccttccaccaccaccgccagcatgggcgaggtgttcggcaaaagcaccgcgaacgtctaccaccaccccagcgccaacgtctcctccaatttctatagcacggtgggcaggaacggggtcctgccgcaggctttcgaccagtttttcgagacggcgtacggcacggcggagaacccgtcctccgcggactatccgccggacaagagcggcgagaaggcgcccgcggccgccggggcgacggcggcaacttcaagttcggagggcggctgcggcggggcggcggcggcggcggggaaggagaggcgaaggcggccggagagcggcagcagccccgagtcatcttccggcaacaatgaggagaaatccggcagctccagtggacaacggacccgtaaaaagagatgcccctacaccaaatatcagattagagagctagaaagggaattcttcttcagtgtctacataaacaaagagaaacgcctccagctctcccgaatgctcaatctgaccgaccgccaagtaaaaatatggtttcaaaacagaagaatgaaagaaaaaaaaattaacagggaccgattacaatattactcagctaatccactactttaaaactcgtagcgtttttcaagacgagattaaattcagatttcgcccttgacaaggtcaagccacgaggttacgtggaggaaggaggtgtgtatctgacgggactcgaagaacccgaggttttccgtacatgtaaatctgctctggaccttccgtgacggtttattgttttgtctatatatttacgtaccaactggaatcggtttgattttgccacacgtggcgtccatccatttccaccgcgcgcgtcacctccgagcgcccggcccaacgcctctcaccttcccgggcaccgcggctccgggaggggacgggggtgtccccgtgtcccgctgccccctcggagcgtggcgtgggcaccggcaccgcgagcggccgcagccgggacgcaaactttgggaaacgatctctcttccttcccggaggaaaaacgtctgtggttgaggcagtgcgccattgcccatgggtttgaaaggggaattaagggaggggggagagaagtaaaggggaggggggggggggggggggcgacgtgcctacaccttcacgaggccgaccacgagcagttgtaacgtggatgtagcgatgggtacgatagtgtttcctttggggtgggaggaagcggggaagggggtgggaagagaaagaaccgaaagactgaaatatttacttaaaaaagaaaaaaatcaggtataaattttgccatacatcgcaaggaaacaatcactgaaaaggcaaagaaaagaaaaacaaagcgaagatttctccagttgtaactagctctcgttttatttatgacaacggcctgcgcgttgccatcttttcggagacaaatcatatttaaatgctaaaaataaagcgtcaaaggggggaaaaaaaaagaagtgtgaatttcagcgttttaaaagaaaaaaaaataaggagaggaaacgaacctcccggcttctggctcgcaaactttcttcaggaaatacctgtggagaacgacagtttagcaaataccacacaacacttaattgaaacttggagttgtgcaatgcgctaacgttggatcattaaaataactcaatcgcatgctcttgtaaaggtgaccagtgaggagtcgaatcagaagccaaacagtgtaaatacggtcgttttgttgtcgtctactttaaatgtcacgagctctactttgtcgcccagccgacgtatgcaaagaacggagagttgttcggagttattttaagtatctataaatatatatatttccctgcaggaaccaaagcgtgaaaaaataataaaaaaaaataaataaaaaagcgatttaaaaaaagaaaaagagagaaaaaaaagacggaaaatatttaaaattctatatcagtttacaaaggctacggagttctatcgttaaggtaatttgctgttgagaatatctgaatgtatatttcatacaggagcgatgttttacaagacttgtaaataataaaaagaggaacccatgacctattttattcgaatgcctttttttttttttttccctgatccttttttttccccccttcctttggggctgaagggtgtggggtctctttacatgtgcaacaaagtggtgatgaggaagttttttgatgaatacatttaccaaatggatgtaagttctttgtcacggttcaccaaacgcggtatctttatatgacatcactgttttccgtatgtatcgactatgtgtatataccgtttttcttttaatatgcgaaagtatttggttgcatgtatacagtggagcagcgcacaaggcaaataaaaacgatggaaacttta

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