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Previous release (v1)
2026-01-17 20:56:23, GGRNA.v2 : RefSeq release 232 (Sep, 2025)
LOCUS NM_204289 2735 bp mRNA linear VRT 01-MAY-2025
DEFINITION Gallus gallus heat shock protein 90 beta family member 1 (HSP90B1),
mRNA.
ACCESSION NM_204289
VERSION NM_204289.2
KEYWORDS RefSeq.
SOURCE Gallus gallus (chicken)
ORGANISM Gallus gallus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
REFERENCE 1 (bases 1 to 2735)
AUTHORS Tang,H., Finn,R.D. and Thomas,P.D.
TITLE TreeGrafter: phylogenetic tree-based annotation of proteins with
Gene Ontology terms and other annotations
JOURNAL Bioinformatics 35 (3), 518-520 (2019)
PUBMED 30032202
REFERENCE 2 (bases 1 to 2735)
AUTHORS Xu,J., Xue,C., Xue,D., Zhao,J., Gai,J., Guo,N. and Xing,H.
TITLE Overexpression of GmHsp90s, a heat shock protein 90 (Hsp90) gene
family cloning from soybean, decrease damage of abiotic stresses in
Arabidopsis thaliana
JOURNAL PLoS One 8 (7), e69810 (2013)
PUBMED 23936107
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 2735)
AUTHORS Burge,S., Kelly,E., Lonsdale,D., Mutowo-Muellenet,P., McAnulla,C.,
Mitchell,A., Sangrador-Vegas,A., Yong,S.Y., Mulder,N. and Hunter,S.
TITLE Manual GO annotation of predictive protein signatures: the InterPro
approach to GO curation
JOURNAL Database (Oxford) 2012, bar068 (2012)
PUBMED 22301074
REMARK Publication Status: Online-Only
REFERENCE 4 (bases 1 to 2735)
AUTHORS Kim,D.W., Lee,H.N., Song,J.E., Jung,K.J., Yang,W.M., Kwon,K.,
Jeon,G.S., Lee,Y.H., Chung,C.K. and Cho,S.S.
TITLE Expression of transferrin binding protein in the capillaries of the
brain in the developing chick embryo
JOURNAL Neurochem Res 33 (11), 2288-2293 (2008)
PUBMED 18459044
REFERENCE 5 (bases 1 to 2735)
AUTHORS Hayes,G.R., Himpler,B.S., Weiner,K.X. and Lucas,J.J.
TITLE A chicken transferrin binding protein is heat shock protein 108
JOURNAL Biochem Biophys Res Commun 200 (1), 65-70 (1994)
PUBMED 8166742
REFERENCE 6 (bases 1 to 2735)
AUTHORS Kleinsek,D.A., Beattie,W.G., Tsai,M.J. and O'Malley,B.W.
TITLE Molecular cloning of a steroid-regulated 108K heat shock protein
gene from hen oviduct
JOURNAL Nucleic Acids Res 14 (24), 10053-10069 (1986)
PUBMED 3027654
REFERENCE 7 (bases 1 to 2735)
AUTHORS Kulomaa,M.S., Weigel,N.L., Kleinsek,D.A., Beattie,W.G.,
Conneely,O.M., March,C., Zarucki-Schulz,T., Schrader,W.T. and
O'Malley,B.W.
TITLE Amino acid sequence of a chicken heat shock protein derived from
the complementary DNA nucleotide sequence
JOURNAL Biochemistry 25 (20), 6244-6251 (1986)
PUBMED 3024703
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from
JAENSK010000012.1.
On Sep 23, 2021 this sequence version replaced NM_204289.1.
##Evidence-Data-START##
Transcript exon combination :: M14772.1, AF387865.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA103992543 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-155 JAENSK010000012.1 45146232-45146386 c
156-255 JAENSK010000012.1 45145793-45145892 c
256-397 JAENSK010000012.1 45144975-45145116 c
398-514 JAENSK010000012.1 45144782-45144898 c
515-846 JAENSK010000012.1 45144166-45144497 c
847-958 JAENSK010000012.1 45143274-45143385 c
959-1078 JAENSK010000012.1 45142468-45142587 c
1079-1195 JAENSK010000012.1 45141857-45141973 c
1196-1333 JAENSK010000012.1 45141245-45141382 c
1334-1411 JAENSK010000012.1 45141085-45141162 c
1412-1477 JAENSK010000012.1 45140939-45141004 c
1478-1747 JAENSK010000012.1 45140398-45140667 c
1748-1993 JAENSK010000012.1 45139937-45140182 c
1994-2130 JAENSK010000012.1 45139534-45139670 c
2131-2209 JAENSK010000012.1 45139095-45139173 c
2210-2365 JAENSK010000012.1 45138839-45138994 c
2366-2464 JAENSK010000012.1 45138212-45138310 c
2465-2735 JAENSK010000012.1 45136537-45136807 c
FEATURES Location/Qualifiers
source 1..2735
/organism="Gallus gallus"
/mol_type="mRNA"
/db_xref="taxon:9031"
/chromosome="1"
/map="1"
gene 1..2735
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="heat shock protein 90 beta family member 1"
/db_xref="CGNC:49067"
/db_xref="GeneID:374163"
exon 1..155
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
CDS 107..2494
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="endoplasmin; heat shock protein 108; HSP 108; heat
shock 108 kDa protein; transferrin-binding protein; heat
shock protein 90 kDa beta member 1; 108K HSP; 108K heat
shock protein"
/codon_start=1
/product="endoplasmin precursor"
/protein_id="NP_989620.2"
/db_xref="CGNC:49067"
/db_xref="GeneID:374163"
/translation="
MKSAWALALACTLLLAASVTAEEVDVDATVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIKEIREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNMLHVTDTGIGMTKEELIKNLGTIAKSGTSEFLNKMTEMQDDSQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFSVIDDPRGNTLGRGTTITLVLKEEASDYLELDTVKNLVKKYSQFINFPIYVWSSKTETVEEPVEEEEAKEEKEETDDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKTFSKEHDDPMAYIHFTAEGEVTFKSILFVPNSAPRGLFDEYGSKKSDFIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEKYNDTFWKEFGTNVKLGVIEDHSNRTRLAKLLRFQSSHHESNLTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFEESEKSKESREALEKEFEPLLNWMKDKALKDKIEKAVLSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKENEDDKTVSDLAVVLFETATLRSGYMLPDTKEYGDRIERMLRLSLNIDLDAKVEEEPEEPEDAAEEAEQDEEEVDADAEDSETQKESTDVKDEL"
sig_peptide 107..169
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="COORDINATES: ab initio prediction:SignalP:6.0"
mat_peptide 170..2491
/gene="HSP90B1"
/gene_synonym="hsp108"
/product="Endoplasmin. /id=PRO_0000013601"
/note="propagated from UniProtKB/Swiss-Prot (P08110.1)"
misc_feature 227..235
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="propagated from UniProtKB/Swiss-Prot (P08110.1);
Region: SRT pseudosubstrate motif.
/evidence=ECO:0000250|UniProtKB:P14625"
misc_feature 287..289
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255; propagated from
UniProtKB/Swiss-Prot (P08110.1); glycosylation site"
misc_feature 350..928
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="Histidine kinase-like ATPase domain of human
cytosolic Hsp90 and its homologs including Escherichia
coli HtpG, and related domains; Region:
HATPase_Hsp90-like; cd16927"
/db_xref="CDD:340404"
misc_feature order(353..358,365..367,377..379,602..604,686..688)
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:340404"
misc_feature order(410..412,422..427,431..436,443..445,542..544,
548..550,554..556,560..565,587..592,596..616,680..700,
734..736,740..742,833..838,842..844)
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:340404"
misc_feature 422..424
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255; propagated from
UniProtKB/Swiss-Prot (P08110.1); glycosylation site"
misc_feature order(590..592,698..700)
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="ATP-lid; other site"
/db_xref="CDD:340404"
misc_feature 752..754
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000269|PubMed:8166742; propagated from
UniProtKB/Swiss-Prot (P08110.1); glycosylation site"
misc_feature 872..2368
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="Hsp90 protein; Region: HSP90; pfam00183"
/db_xref="CDD:459703"
misc_feature 971..1072
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="propagated from UniProtKB/Swiss-Prot (P08110.1);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1436..1438
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255; propagated from
UniProtKB/Swiss-Prot (P08110.1); glycosylation site"
misc_feature 1445..1447
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="Important for ATP hydrolysis.
/evidence=ECO:0000250|UniProtKB:P41148; propagated from
UniProtKB/Swiss-Prot (P08110.1); other site"
misc_feature 1544..1546
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255; propagated from
UniProtKB/Swiss-Prot (P08110.1); glycosylation site"
misc_feature 1607..1609
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255; propagated from
UniProtKB/Swiss-Prot (P08110.1); glycosylation site"
misc_feature 2357..2491
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="propagated from UniProtKB/Swiss-Prot (P08110.1);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 2480..2491
/gene="HSP90B1"
/gene_synonym="hsp108"
/note="propagated from UniProtKB/Swiss-Prot (P08110.1);
Region: Prevents secretion from ER"
exon 156..255
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 256..397
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 398..514
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 515..846
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 847..958
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 959..1078
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1079..1195
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1196..1333
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1334..1411
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1412..1477
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1478..1747
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1748..1993
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 1994..2130
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 2131..2209
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 2210..2365
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 2366..2464
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
exon 2465..2735
/gene="HSP90B1"
/gene_synonym="hsp108"
/inference="alignment:Splign:2.1.0"
ORIGIN
gctccagcgggttcggcggcggtgcgggaggcgttgcggtggggttctacggctcggggcagggcgttgggccgtttttctctcagcatcagcaggccgcggcatcatgaagtcagcgtgggcgctggctctggcatgcacgcttctcctggccgcatcggtgaccgctgaggaggtggatgtggatgcgaccgtggaagaagatctgggtaaaagtagagaagggtcccgaactgatgatgaagttgttcagagagaggaagaagctatccagctggatggcctaaatgcatcccagatcaaagaaatcagagaaaaatctgagaagtttgcctttcaagcagaagttaacagaatgatgaagcttattattaactctttatataagaacaaagagattttcctgagagagcttatttcaaatgcttcagatgctttggataagatacgcttaatatccttgactgatgaaaatgctcttgctggtaatgaggagctcactgttaaaatcaagtgtgataaagagaagaacatgcttcatgttacagatacgggtattggcatgacaaaagaggagttgattaaaaaccttggtaccattgcaaagtctggtacaagtgaattcttaaacaagatgactgaaatgcaggatgatagccagtcgacatctgagttaattggccagtttggtgttggcttttattctgctttcttggtagcagacagagttattgtcacatcaaagcacaacaatgatacccaacatatttgggagtcagattcaaatgagttctctgtgattgatgatccaagaggaaacactctgggacgtggcacaaccataacccttgtcttgaaggaagaagcctctgattatcttgagttggacactgttaaaaatctagtcaagaaatattcacagttcataaacttccccatatatgtgtggagcagcaagacagagactgttgaagagccagttgaagaggaggaagcaaaggaggagaaagaagaaacagatgatgatgaagcagcggttgaagaggaggaggaagagaagaaaccaaaaactaagaaggttgaaaagactgtctgggattgggagctcatgaatgacataaaaccaatctggcagagaccatctaaagaagttgaagaggatgaatataaagctttttacaaaaccttttccaaggaacacgatgatccaatggcttacattcattttactgctgaaggggaagtaactttcaaatcaatcttgtttgttcctaattctgctccacgtggcttgtttgatgagtatggatccaaaaaaagtgatttcattaagctgtatgttagaagagtgttcatcactgatgacttccatgacatgatgcccaaatatcttaacttcgttaaaggtgttgtggattctgatgatcttcctttgaatgtatctcgtgaaacacttcagcagcataagttactaaaggtgatcagaaagaagcttgttcgtaaaaccctcgatatgatcaagaaaattgcagaagaaaaatacaatgacacattctggaaagagtttggtactaatgtaaagcttggagttattgaagatcactccaatcgcacacgactggctaaactgcttcgcttccagtcttcccatcatgaaagtaaccttacaagccttgaccaatatgtggaaagaatgaaagagaaacaagacaaaatttatttcatggcaggtgccagcagaaaggaggctgagtcttcaccatttgttgaacgccttctgaaaaagggctatgaagtgatctacctgactgaacctgtagatgaatactgcattcaggctctgccagagtttgatggcaagaggtttcagaatgtagcaaaggagggagttaagtttgaggaaagtgaaaagtccaaggagagtcgtgaagccttggagaaggaatttgaaccactcttgaactggatgaaagacaaagctctaaaggacaagattgaaaaggctgtgctgtctcaacgtctaacacagtctccatgtgcactcgtggctagtcagtacggatggtctggtaacatggagagaatcatgaaggctcaagcataccaaactgggaaggacatatctacaaattactatgctagccagaagaagacatttgaaataaatcccagacatccactgatcaaagacatgctgaggcgagttaaggaaaatgaagatgacaaaacagtttcagatcttgcagtggtgttgtttgaaactgcgactttgagatcaggatatatgttaccagacacaaaggaatatggagacagaatagaaaggatgcttcgtttgagtttaaacattgacctggatgcaaaggtggaggaggaacctgaagagcctgaagatgcagctgaggaggcagagcaagatgaagaagaggtggatgctgatgctgaagacagtgaaacacagaaggaatccacagatgtaaaagacgaactgtaaactgcactcacctactgtcctgcactgggaggtcaagagaaggatgtgaattcaattttggtttgttttccactggaaaaggttgagggatggtgtggggtttaagggcaaaggagatttttttttttaagttgacttttctaaaaaaaagaaaacattcctcacgaatgtaaatttgtattatttaactgacttggtgtaaaatcttgtcatgtacaaaataaaatgttcccaaacacca
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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