LOCUS       NM_001396750            8418 bp    mRNA    linear   VRT 05-OCT-2024
DEFINITION  Gallus gallus nuclear factor I B (NFIB), transcript variant 3,
            mRNA.
ACCESSION   NM_001396750 XM_015280081
VERSION     NM_001396750.1
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 8418)
  AUTHORS   Tang,H., Finn,R.D. and Thomas,P.D.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 8418)
  AUTHORS   Burge,S., Kelly,E., Lonsdale,D., Mutowo-Muellenet,P., McAnulla,C.,
            Mitchell,A., Sangrador-Vegas,A., Yong,S.Y., Mulder,N. and Hunter,S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8418)
  AUTHORS   Rupp,R.A., Kruse,U., Multhaup,G., Gobel,U., Beyreuther,K. and
            Sippel,A.E.
  TITLE     Chicken NFI/TGGCA proteins are encoded by at least three
            independent genes: NFI-A, NFI-B and NFI-C with homologues in
            mammalian genomes
  JOURNAL   Nucleic Acids Res 18 (9), 2607-2616 (1990)
   PUBMED   2339052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAENSK010000092.1.
            
            On Oct 25, 2021 this sequence version replaced XM_015280081.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12888541.150249.1,
                                           SRR13267659.100527.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA103992290,
                                           SAMEA103992323 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               JAENSK010000092.1  1260629-1260803     c
            176-707             JAENSK010000092.1  1254051-1254582     c
            708-761             JAENSK010000092.1  1161692-1161745     c
            762-830             JAENSK010000092.1  1150052-1150120     c
            831-951             JAENSK010000092.1  1148166-1148286     c
            952-1070            JAENSK010000092.1  1146326-1146444     c
            1071-1202           JAENSK010000092.1  1129970-1130101     c
            1203-1387           JAENSK010000092.1  1127392-1127576     c
            1388-1476           JAENSK010000092.1  1105003-1105091     c
            1477-8418           JAENSK010000092.1  1086180-1093121     c
FEATURES             Location/Qualifiers
     source          1..8418
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="Z"
                     /map="Z"
     gene            1..8418
                     /gene="NFIB"
                     /note="nuclear factor I B"
                     /db_xref="CGNC:49703"
                     /db_xref="GeneID:396209"
     exon            1..175
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    107..109
                     /gene="NFIB"
                     /note="upstream in-frame stop codon"
     CDS             146..1606
                     /gene="NFIB"
                     /note="isoform 3 is encoded by transcript variant 3;
                     nuclear factor 1 B-type; CCAAT-box binding transcription
                     factor; CTF; NF1-B; NFI-B; NF-I/B; nuclear factor 1/B;
                     TGGCA-binding protein"
                     /codon_start=1
                     /product="nuclear factor 1 B-type isoform 3"
                     /protein_id="NP_001383679.1"
                     /db_xref="CGNC:49703"
                     /db_xref="GeneID:396209"
                     /translation="

MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEFREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQPGSPSHNDPAKNPPVYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGELPSQPYYHDMNSGINLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTMKKPEKPLFSPTSPQDSSPRLSTFPQHHHPGIPGVAQSVISTRTPPSPSPLPFPAQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQLRICDWTMNQNGRHLYPSASEDTLGITWQSPGTWASLVPFQVSNRTPILPTNVPNYGLNIIGEPFLQAESSN"

     misc_feature    173..286
                     /gene="NFIB"
                     /note="Nuclear factor I protein pre-N-terminus; Region:
                     NfI_DNAbd_pre-N; pfam10524"
                     /db_xref="CDD:463134"
     misc_feature    350..664
                     /gene="NFIB"
                     /note="MH1 domain; Region: MH1; pfam03165"
                     /db_xref="CDD:460833"
     misc_feature    770..>1390
                     /gene="NFIB"
                     /note="CTF/NF-I family transcription modulation region;
                     Region: CTF_NFI; pfam00859"
                     /db_xref="CDD:459967"
     misc_feature    914..1252
                     /gene="NFIB"
                     /note="propagated from UniProtKB/Swiss-Prot (P17924.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1295..>1567
                     /gene="NFIB"
                     /note="multidrug efflux RND transporter permease subunit
                     AcrB; Region: PRK15127"
                     /db_xref="CDD:185081"
     misc_feature    1331..1357
                     /gene="NFIB"
                     /note="propagated from UniProtKB/Swiss-Prot (P17924.1);
                     Region: 9aaTAD. /evidence=ECO:0000250|UniProtKB:O00712"
     exon            176..707
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            708..761
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            762..830
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            831..951
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1070
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1202
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1387
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1476
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..8418
                     /gene="NFIB"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtggtgattcagggcagagccccgtcctgattgatttcatcttcctcgagtctcagatgactgtaaaatgaacagatgaaattattccttttttgaggctttttcttaggggctctccgggcagcgcgtttgcaaaagcgaagtcatgatgtattctccaatctgtctcactcaggatgaatttcacccgttcattgaggcacttcttccgcatgtccgtgcaattgcctatacttggttcaacctccaggctcgaaaacgcaagtacttcaaaaaacatgagaaacgaatgtcgaaggatgaagaaagagcagtcaaggatgagctactaagcgaaaagcccgaaattaaacagaagtgggcatccaggctcctcgccaagctgcgcaaagatattcgccaagagttccgggaggattttgtgctcacggtgactgggaagaagcacccgtgctgtgtattgtccaatcctgaccagaagggtaagattaggaggatcgactgcctgagacaggctgacaaagtctggcgtctggatctagtcatggtgatcctgttcaaaggcatccccttggaaagtacggatggagagcggctcatgaaatccccacattgcacaaatccagcactttgcgtccagccacaccacataacagtatcagtcaaggagcttgatttgtttttggcatactacgtgcaggagcaagattctggacaaccaggaagtccaagccacaatgatcctgccaagaatccaccagtgtatcttgaggacagttttgtaaaatctggagtgttcaacgtgtcagaacttgtgagagtgtccagaacacctataacccaaggaactggagtgaacttcccaattggagaacttccgagccagccgtactaccatgatatgaattctggtataaatctgcagaggtctttatcctctccaccaagcagcaaaagacccaaaactatctccatagatgagaatatggagccaagcccgacaggagacttttatccttctccaaattcaccagctgcgggaagtcggacatggcatgaaagagatcaagatatgtcttctcctacaatgaagaaacctgaaaagcctttgtttagtcctacttctccccaggattcttcaccaagactgagcactttcccccagcatcaccacccaggaatcccaggagttgcacagagtgtcatctcaactagaactccaccttcaccttcaccattgccatttccagcacaagctattctccctcctgccccgtctagttacttctctcatccaacgatcagatatcctccccacctgaatcctcaggatactctgaagaattatgtaccttcttacgacccgtccagtccacagactagccagctgaggatttgtgactggaccatgaatcaaaacggcaggcatttataccccagtgccagtgaggatacattgggaattacttggcaaagtcctggtacctgggctagcttggttccttttcaagtatcaaacaggacaccgatcctgccgacaaatgtcccaaattatggtttgaacataattggagagcctttccttcaagcagaaagcagcaactgagggaaaaaataaaaagaaaaattaggaaaaagaaaaaaaaaaaaaagaaggaagacgggatgggagaagaaactgaagaacgaagaataaatagaccagcaattgcagcacttacaatcactaattcccttatggtcgaaactgaaatgacatacaaagggtcgatgatatttcactgatgggtagaacgcagctcctgctaagtagcctttgttatatgaagtccgctgggaaatagatgttctgtctctgacaatatattttaactgactttctagatgccttaatatttgcatgataagctagttttattggtttagtattcttgttgtttacgcatgggatcactattcctggttatctcacaaaacaaaggctaggcagcagcagcagatttgcaggaggacaagggctgtaagccagccgttttctcaacactctgatttctaaatgtttaaaaaagaaaaaagaaaaaaaaaagctctgtagcctttagttatcagtatggatttattaaactttggcccttgactcagccttttctagtgtgttacccagcttgaaattttcaatcagaatgaacacacacgctctatgtaagagatgcctctatgtaggtgaaagtgttatcttttcatgcaacagtaaaaaaaaaaaaaagaaaaaaaagaaaaaaaaaccatacaaactacaaactttttacccactaaagaaacacttagagaggcaagtgcaatttaaaaaagttgtatcaaaggggtcatcattataagtccttcagcccttggactctaaattgaggggattaaaaaaaggaattaaaatttactttgaacaaatttatttttcccctcagtttttgagggcattaaaaggcattacatcaagacaaatcatgtccttgagaaaaataaatcaatgaaaacacagcacttatgttggtttagctgctgcctccacaaaggggtagaatttatttatttaaagttactggttgcatcaagaacccatagggtttatatttttctgtataatctgcatcatagagacaaagagataggcaaatccatgccaaaagggcaaagcttactgtttacaaactggtaataccaggatggggataagatttatttaaataatgcactctctaagtctaattacagggtgctgaaaacttgcatggtgctttcagaagttagccttgttcaacagatttcacatattgacagaaatataatgtgcatgggcagacattttgcctctgtgtctcttaaaaagtaattaattaaaatactctttccagtaatcccgatttgcacgaaaatataatgtccacattacgtgccttgccttgaaatctaaaaaatgaaaaaaaaaacaacaaaaaaatacaaaaaatccacaaaaacaaacaaaaaaaaattgacatcactacacttgttttgctgcatttattatcatttaaatctttaccatttttatgacaaaatattttgtactccagatgggaaaaaaagtgtgacatcatggattttttagacagttatatctttatctcacatttataaagcatatcatggctgtgtataattgccgcttaagaattgtaatcgaccagcaatattttcagtattttggtgtttttttctattaacctttcatgtttttcatcttccaattaatattgggggggggaggggggggagggggttcaaatttatacgaattatgcaataccaagttttgcctatgtaggtagtgcttttagctgtattggttattataggtaagtacacagatttaaaagaaaaaaaaaaaagaataatgtatgctttgtttttgttttgtttcttggtttttttgttttttgttttttgttttttttttttttaattgaccaaagtgggtactgctatttttgcagtgtgatgaggtccttttatgtactgagagatggacggggatttttttttttatacatatatatatattctggggtgggtggggatgatttttaacactttacagtgtagctgtgaagcagtgcacccttagccaggcaagggctgcaaagcgactgttctgcctactgtgacaaactttcaaatcggttccctcttttaacttcccacctggggtgcaagctgaaatcatttctggatttaaaaaataaataatgaattctgttggaggcagacttgacttgaggaaattgttttactacggatttctttagagagagagagagagggaaagggagaaagagagcgatagaaacaggagagagaggcagccggagggagaaggaggtcaggacacacagcgagacaaagccttcccactctggtgaatacactacatctgaaagtgttcgtgttagaaatgtttttaacttagaaagatgggtgctttgtctaggaaatgcacgtagatggccaaaatcttagctggcataactccactggcttcagttgacttcagagctgttcctgcagagaatttgcctcctttagtctgcgtggctggtaaatattttcttttcccctacaacaaaactattttttgaagtttgtcaactcacagtgtctgagttccaatcttcggtctgctcataccacatcagaggtttgcaaagtcttctcatacagcaggtcagatggagagctctgggctgtagcaggaaaggagcttcagaatgggtggaattagagtatggtgtaaacaaaagtgcatttccagtaaaaccagaccttacagattagtcatgatctcctgttgctggagacctcttatgccctggggatgcatcttatctatagctcagtgtagggagaacaccttcatgcgcaagcaaaggatggaaaagtctcgaaatagggtatcctttcagccttctgtggttgtctcttcatttcaaaggttttcccaccctggagcagccccagagtatgagtccagctacaggtcctgggtgctgacacactgacattggtcccttctcaccttgaatcatatcatagaaacatagaatcatagaatggcctgggctgaaaaggacctcaaagatcatccagtttcaaccctcctgccatgggcagggtcaccaaccactagaccaggctgcccagagccacatccagcctggccttggccagcacatggctgctgtgaggctgtggtgatggcacatactgcatgtctctgcagcaggcagagcatggacagatactgaagcagaagctgtaggaaagcagatctttatctgtatctaaactgagaaggaaaggaaaaaagccggaggaaaaaaaaaaaaaagaaaaagaaagaaaagaatccaatatcaaagttatgtttcacttttcctgagccccgtggtaagtgacttcatttcctaagaatattgctgttaagactagctgaaatgtgggagacccacccagagcatatctcaggctctggcctggtgaaataaatgatgttattgccttttctgctggacccaatgggtcagggggcactgtccatgctgcggggagcaggctgtcccctaaagttttaagtgcatgccaggatgaaaccgaaatgtgtgcgattgccaaaaggacaagtatccctgagggaagatggatggctttatgcgagcttttctgttatctctgacctcttgtatgaaaaaaaaaaaaaaaaaaaaaaagaagagcttgcagatgtgatatttttaaaagcagattccttccatgcgaatgaattggttttgttaagcaactgtgggttttttcacacgtgcctctctgatagaaaagtctggttggaagaaaacacccttttcatttatgtttttgtttgtttgtttttgaagctcagcagtcaaaagattaagataacattgagaactcaaatccagtctctggcctcctccttcaccaggaagtgtattctgactaaatcaagccaccccgttctatgtgcactgttctgcctttattaagttgctttgcagccctggcctcatggctgtgccactgaagtgtgttccccctggagtgacatgaacgtttgaggcttgactatggaaaaaaaaaaaaaaaaaaaaaaaggcagtgaaggagactgtacataaagacatggcaaaaatattaattatagcaatatagttgtggggtgatgttcaggtgggcagctccattgaaaatatgtgaatggatttgtgaagctgcaagtagcgagaagaaaggaggattttctgaatgaaccgcctaccttgtagacagtaatttgtacactgtatagttttgttaagatttttttttttttaattaaaatacccttgtttgtaaagctaactttttaacaattataatggaaatatatgtcatttccatttttaaagtaaacaagaatattccttgtttggaagctggacttgggttaaaactctccagtttcttaatttatgtgttaaaaaaaaaaataaataaaaaatttgtccatgttagcagatatttcacagattcctgtgcttgaaaagcataggttactaatcctttaaaaatgtaaatggagaaaagttatattttatgaaggttattttgttgtatttagtattggaaaagttggttttcagagcatttcaaaatgttggaagcaccactgtctttttattagtatatatggcctttagcaaaagtttttgtgattgttacatgatggtatttaagattaggttcacagagcaattcaggataggcagagaataaaaacagtacttatgtctcacatagctgtgtcctcagggagcagaattttggatttgcaacttgtagcttcataaggacttaatgaaagagattgcacaaggacatactcagctgtgacaccggggtgtgttctgtacctaaatctaaattatatttactgtgtgaggttatgaaggctgcagaaagttatcccatattcagtgtacagtattcacttttaatgaaacaactctttaatgttgctggcagtaaggtcccaagcatgacatccaatatagtttatatgatcctgtcaaggtcttttgttaacattaaccagctgcaatgctcctggacttttttttttttttaaattgggtttctatagaaaacttaaaaaaaaaaaagaaaaaagaaaagtaaaattgtatgtgggctaagaaagtgaagcaggaaaagctcaaaattgaacgttcaactccagaccgaaggagctgcaaactctccctctcacttgcactttctgctacttcccaattttttcctaattcctcaaaattatgtgggtgtggtggagcactgcagttggaggataacacggaccactgattttgccctttaaccctgcacaatgacctttgcatcagccaaacttattgccatgacaactctttgtactgtttccacgccacagctctgttggtcacattgttaaaagcaaaggggacaagtccaagacggtcaatttttacattttttgtcgcaattttttcttcagtggttgtaagtaggtttttgtttcttttttttttctttttttctttcttttttttttttttaataataaaagggttcactagttattactctttaggaatatctgtgtgttgcaattcaaatgtatgttaaatttgtgaaaggggcttcagtgccactagcatcgtgatatcctagaataagcctttcatacttttattgcatgatacagtaacagtaaaacagaaggtggtctaaatagatggaaagcagtgtgagctagtgacactaaagccagtctttgtattactgtatttttgacagaatggttttgaaactgtgctacagggactgatgtggcaaatgtatctctatatgcagaaagaagttttttaagaagtatggcttattatgcattcttcattgagggcattgaagttgcatggactgataaaagttgatgcaaaatgagaaagaaacaaaaaccagcaaaatgtttaccaaaaaatctcaaacaaatgagcagtgcctgttcaatttcacagtctctgttgagttcagttgtaaatatgtttcagataacatttttcttcaaaaaaaaataaaaataaaaatctctacaacagtgtagaatgtgaggggttcctcaagtcccaggcataggcttctcatgagctgcattaggttatgtcttcatcaagctgttaatttgtgcttatatcatatagaacttttagcaaactgggaagaggtgccccatctcaatgatatttctctgagaacaacttttgtagggctgtgtgtttctttagatacatttagtacaactgtagtgacaagtagtcagttattgcttgctagctacacaccagggttgatccattttaaaacttttggcatttttccccatactgtaggccataaatcctgaaggttacattttaattaaaaagtaggtgcgtgcacaatccttgtgtaacgaaacttctcttgtaggatgcattacagtacagctacttaactttggaagtaaggccctctggcatgagacctgtttttagcctgagtgttaacaaaggtttttattgtgcctggttggaggataataatgttctttttggtacttttttttaggttacaaatgaactcaactgccacaagttttaaactggtgtaaatcaagcttgacttaatgtgattgttactgttatatccagcctatactgctagcagctgctcatactgcagtcaattactggaagcggatatatttcctatgcaaaaactgtttaaacaataaaaatgagctatgctacagaa

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