LOCUS       NM_001396448            4934 bp    mRNA    linear   VRT 23-SEP-2023
DEFINITION  Gallus gallus protocadherin gamma subfamily C, 5 (PCDHGC5), mRNA.
ACCESSION   NM_001396448
VERSION     NM_001396448.1
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 4934)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4934)
  AUTHORS   Han MH, Lin C, Meng S and Wang X.
  TITLE     Proteomics analysis reveals overlapping functions of clustered
            protocadherins
  JOURNAL   Mol Cell Proteomics 9 (1), 71-83 (2010)
   PUBMED   19843561
  REMARK    GeneRIF: RNA interference knockdown of both PCDH-alphas and
            PCDH-gamma showed that PCDHs have redundant functions in regulating
            neuronal survival in the spinal cord.
REFERENCE   3  (bases 1 to 4934)
  AUTHORS   Cronin KD and Capehart AA.
  TITLE     Gamma protocadherin expression in the embryonic chick nervous
            system
  JOURNAL   Int J Biol Sci 3 (1), 8-11 (2006)
   PUBMED   17200686
  REMARK    GeneRIF: Results suggest that pcdh-gamma may function cooperatively
            with other cell adhesion molecules in neuronal differentiation and
            establishment of neural networks in several areas of the developing
            brain, particularly regions involved in visual processing.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4934)
  AUTHORS   Tanabe K, Takeichi M and Nakagawa S.
  TITLE     Identification of a nonchordate-type classic cadherin in
            vertebrates: chicken Hz-cadherin is expressed in horizontal cells
            of the neural retina and contains a nonchordate-specific domain
            complex
  JOURNAL   Dev Dyn 229 (4), 899-906 (2004)
   PUBMED   15042713
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAENSK010000256.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns
                              SAMEA103992290, SAMEA103992323 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2598              JAENSK010000256.1  89485-92082
            2599-2657           JAENSK010000256.1  99814-99872
            2658-2746           JAENSK010000256.1  108044-108132
            2747-4934           JAENSK010000256.1  113500-115687
FEATURES             Location/Qualifiers
     source          1..4934
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="13"
                     /map="13"
     gene            1..4934
                     /gene="PCDHGC5"
                     /note="protocadherin gamma subfamily C, 5"
                     /db_xref="GeneID:427617"
     exon            1..2598
                     /gene="PCDHGC5"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    91..93
                     /gene="PCDHGC5"
                     /note="upstream in-frame stop codon"
     CDS             139..2964
                     /gene="PCDHGC5"
                     /codon_start=1
                     /product="protocadherin gamma-C5"
                     /protein_id="NP_001383377.1"
                     /db_xref="GeneID:427617"
                     /translation="

MRADMESVSLQRPAWKWQVLSLFLLCGWGWVSGQIRYSVLEESEVGTLVGNVAQDLGLKVEQLVGRRLRLGSEESRQHFAVRLDSGVLVVSERLDRERLCGAAASCVLSVQVVAENPLQLFRLEVEILDLNDNSPSFPTTHRSLRIAESAAVATCFPLESAQDPDVGTNAVGSYWLNPNSHFSLDVKQLQDGKLFPELVLERALDREERPELQLVLTAVDGGSPARSGTAQITVQVLDINDNAPAFDRATYKVQILENTPVGALLLQLNASDPDEGPNGETQYSFGVHTSEAVRRLFALDPNSGEVRVSGELDFEESPFYEIHVRARDRGVPEMEGHCVLQVEVEDANDNPPEVLLTSLLNPVPEDTPPETVVGLFNVRDRDSGANGDVSLEISPNVPFAVKSLQNHFSLVTRQSLDRETTSQYVVQLTAQDSGSPVLTTSLTLLLNVSDVNDNSPRFLQPSYDAFLPENSPPGSLLCTVSASDPDDGDNSRLVYSIEGHVQGAPASSYVHINPNNGNLYAQRTFDFELLQVLPVSVVVRDSGSPSLHANVTVYIFVLDQNDHPPTILHPAGDDDVPTLERVPLSAPPGYLVTKVTAVDADAGYNAWLSYRLLPESTEPSLFHVSQYTGEVRTARVLRDTDVAVQQLLILVADNGDPPLSTTVTISVALEEEALEESYKPRDFLAGTKEKPDLTLYLIIALAAISTVALATVTLLAAWCLRRRGRAATSPRCCWAAESPSRDFFNHSSPKLQLCSDGTLKYMEVTLRPTDAQSQCYSTCFSPDSDRSDFTFLRPCPPPGTLPREPGAFLSAAGTLRDAGQQAQPNPDWRFSQTQRPGTSGSQNGEEGGAWPNNQFDTEMLQAMILASANEAADVNATLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSTATLSNAAGKRDAKPSGGNKKKSGKKEKK"

     misc_feature    238..486
                     /gene="PCDHGC5"
                     /note="Cadherin-like; Region: Cadherin_2; pfam08266"
                     /db_xref="CDD:400525"
     misc_feature    565..864
                     /gene="PCDHGC5"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(580..585,751..753,757..759,850..852,856..861)
                     /gene="PCDHGC5"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    886..1188
                     /gene="PCDHGC5"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(907..912,1075..1077,1081..1083,1174..1176,
                     1180..1185)
                     /gene="PCDHGC5"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    1225..1500
                     /gene="PCDHGC5"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(1231..1236,1387..1389,1393..1395,1486..1488,
                     1492..1497)
                     /gene="PCDHGC5"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    1522..1827
                     /gene="PCDHGC5"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(1543..1548,1714..1716,1720..1722,1813..1815,
                     1819..1824)
                     /gene="PCDHGC5"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    1879..2139
                     /gene="PCDHGC5"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    2212..2517
                     /gene="PCDHGC5"
                     /note="Cadherin cytoplasmic C-terminal; Region:
                     Cadherin_C_2; pfam16492"
                     /db_xref="CDD:435374"
     misc_feature    2605..>2889
                     /gene="PCDHGC5"
                     /note="Cadherin C-terminal cytoplasmic tail,
                     catenin-binding region; Region: Cadherin_tail; pfam15974"
                     /db_xref="CDD:435046"
     exon            2599..2657
                     /gene="PCDHGC5"
                     /inference="alignment:Splign:2.1.0"
     exon            2658..2746
                     /gene="PCDHGC5"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..4934
                     /gene="PCDHGC5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cccctccgctcggatgctggcagccgagctgcagcctcctacagccccggagctgcttcccgagctggggaacagagagccggggatttttagcggctccgcaaggccggctgtgtcccgggtccggtcctgggccagatgcgtgcggacatggagagcgtcagcctccagcgacccgcctggaaatggcaagtactgagtttgtttttgctctgcggctggggctgggtctctgggcagatccgctactcggtgctcgaggagtcggaggtggggaccttggtggggaacgtggcccaggacctgggcttgaaggtggagcagctggtgggccgcaggctgcgcctgggctcagaggagagtcggcagcacttcgccgtgcgcctggacagcggtgtcctggtggtgagcgagcggctggaccgggagcgcctgtgcggagccgccgccagctgcgtgctgtcagtgcaggtggtggcggagaaccctctgcagctcttccgcctcgaagtggagatcctggatctgaatgacaactcccccagcttccccaccacccaccgcagtctgcgcatcgctgagtctgccgccgtggccacgtgcttccccttggagagcgcgcaggaccccgatgtggggaccaacgccgtgggctcctactggctgaaccccaactcccacttctccttggacgtcaagcagctgcaggatggcaaactcttcccggagctggtgctggagcgcgccttggaccgggaagagcggccagaactgcagctggtgctgacagccgtggatgggggcagcccggcccgctcgggcacagcgcagataacggtgcaggtgctggacatcaatgacaatgctccggcctttgaccgtgccacgtacaaggtgcaaatcctggaaaacacacctgtgggagctctgctcctccagctcaatgcgtcagatcctgatgagggccccaatggggagacgcagtactcctttggggtgcacacctccgaggccgtccggcgactctttgcgctggatcccaacagtggtgaggtgcgggtgagcggggagctggactttgaggaatcacccttctatgagatccacgtgcgggcccgtgacaggggtgtgcccgagatggaggggcactgtgtgctgcaggtggaggtggaagatgccaatgacaaccccccagaggttctgctcacctccctgctgaacccagtgcccgaagacaccccaccagagactgtcgtgggactcttcaacgtgcgggaccgagactcgggggccaacggggatgtgagcttggaaatctcccccaatgtgccgttcgctgtaaagtccttgcagaaccacttctcactggtcacacggcagagcttggatcgagagaccacctcgcagtacgtggtgcagctgactgcccaggacagtgggtcccctgttctcaccacgagcctcacactgctcctcaatgtatctgatgtgaacgacaactcaccgcgcttcctgcagccctcctatgatgctttcctcccagagaacagccctccgggctccctgctctgcactgtctctgcttcagatcctgatgatggagacaattcccgtcttgtttactccatagagggccacgtgcagggtgctcctgcttcttcctacgtccacatcaaccccaacaacggcaacctctatgctcagcgcacctttgacttcgagctgctgcaggttctaccggtctcagtggttgtgcgggactcagggtctccatcgctccacgccaatgtcactgtctatatttttgtgctggaccagaacgaccacccccccaccatcctgcaccctgctggtgacgatgatgtccccaccctggagagggtcccgctgtctgccccaccgggctacctggtgaccaaggtgacagcagtggatgcagacgccgggtacaatgcctggctgtcctaccgcctgctgcccgagtccaccgagccctccttgttccacgtgtcacagtacacaggggaggtgcggacggcacgtgtcctgcgggacaccgatgtggcggtgcagcagctcctcattttggtggcagacaacggcgacccaccactctccaccaccgtcaccatcagcgtggccttggaagaggaagccttggaggagagctacaagccccgggatttcctggctggtaccaaggagaagccagacctgaccctctacctgatcattgcgctggcagccatcagcacggtggcacttgctaccgtcacccttcttgctgcctggtgcctgcggcgccgaggccgtgccgccacttctccccgctgctgctgggctgccgaatcaccatcccgggacttcttcaatcattccagccccaagctgcagctctgctccgacggcacccttaagtacatggaggtcaccctgcggcccaccgacgcccagtcccagtgctacagcacctgcttctctcccgactccgaccgcagcgacttcaccttcctgcggccctgtccgccccccggcacccttcctagggaacctggggctttcctctccgccgccggtaccctgcgggacgccggccagcaagctcagcctaacccggactggcgcttctctcagacccagagacctggaacaagcggttcccagaatggagaggaaggtggagcctggcccaacaaccagtttgacacagagatgcttcaagccatgatcctggcctcggcaaatgaagccgctgatgtcaacgcaacactgggtgggggcacaggcaccatggggctgagcgcccgctacggcccccagttcaccctgcagcacgtccccgactaccggcagaacgtctacatcccgggcagcaccgccacactgagtaatgctgccggcaaacgcgacgccaaaccctcgggtggcaacaagaagaagtctggcaagaaggagaagaagtagaaaggagacgtcagagcgggtgggcagcgcgtgccagcactccccaacaccacaggaggacgaatgtggatttgtttttcttttcatttcttggcgatgcaaaagttaggaagcgctgcgaatgtattgtcatcgtcagagctaggagcaggctgcctgctgttaggtctcatgatgaaaagcaatctggaaagctaaagctaacacaaacaagtgccctgtgaatacagctaacgttttatacgacccctcgggtgttaggatacatgaggtcgaaaggcttcggccatatccttggcttcgatttgctcccagatggtccgagagaggcacgaggctctcgctcagcttcgtccagtgtaaataattgtaacacccatctgttaatttatagagctctgatcattttttttttgttgttgttgttatttggaaagaaaaaggaatttcccagcataaagccccacgttccacgttttctgctcttttaacttcgtgaaactcaccctgggttattggtagcggtggatttgtgggtagggagtgcttcagttcctgttcagctgttatccgaaaaaaaagaaaagaaaaaaaaataagaagtgttcgtattgcatgagtcaaagggaacaatgcagggctgcatcctaaacagttattgttctgttttgttttgttttgttttttttcctgaagtacaaccagccatggcctgagagctcctggtgtctgagcggggcttcggcgcggccctggggggctctgagcagacacatctcatccctgcgctgcagtaaatatttatatgtacagtcaatgttcttttggaattaaagctccggggctgggaggggctgctctgcacctcgccatgaccccacgtgtgcgtcacctgcgtcacggctgcactttggaacacacatccccgcaccccccagccccgaggatgtcctcgcatggccacgcagcatggggtgaaggcgctttgtatttggggagtgggggggttgttgggtaccgagtaagtgacagtgggtttagtggcacctggggagcagatttgggtcagggacttatgggctgggggtccctgcaatggtgtgagcccagggatcagctgggataaaacatgggggggtgatgctggctttggggtttccacctcccagagggaacgggaggacgaggagttggatttctccatgctgtgccccttccaagcaggctcagcccggaggagggtcctggtggcctcggtggcactgctggggataccccaagcaccccgtatcacagcatctgtgccccccccaggaaggcagagaggaaatctggcacccaaagtgggtgcgggtggggagagggtggtcccccctcgacccccccccaggggccactcaatttcacataggattttttgctcttttttaatcactaacacttaactcaccccctacacacacactcccccctcccccctccccagcacacacagacacactccggggggcagcagcccctccgcacaccatgcccaccccaccccaaccccacagctgctccacagccccatgtagctaccacccccctcccctagcaatgccgtaggtgaatcgtagtctttgtatttctttttaacctgcaatctgaggtagcgtagcgagtgtcgtgtatttagtggcgtgttatttttatctcagtaactaacttgtggaacagcagtattctcactttctctgtatcttctctccatgtggtctgtgctccgagtgtacatgagatgaaacacgtttgccctctccatgtgtctaatattgaattatacttatatattatatatatgcttatatccttcttatacccatatagaccgacgtcgatgtgttacacgcaagttttatactctaatatttatattgcttttttttttttctttgggaaaaaaaataataaaaatggtttcttctgaa

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