LOCUS       NM_001178132            3009 bp    mRNA    linear   VRT 23-SEP-2023
DEFINITION  Gallus gallus fascin actin-bundling protein 1 (FSCN1), mRNA.
ACCESSION   NM_001178132 XM_414792
VERSION     NM_001178132.2
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Tang H, Finn RD and Thomas PD.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 3009)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAENSK010000257.1.
            
            On Sep 23, 2021 this sequence version replaced NM_001178132.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX933941.1, SRR13267658.19135.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA103992290, SAMEA103992323
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-859               JAENSK010000257.1  4196370-4197228
            860-1016            JAENSK010000257.1  4200859-4201015
            1017-1138           JAENSK010000257.1  4201560-4201681
            1139-1306           JAENSK010000257.1  4201788-4201955
            1307-3009           JAENSK010000257.1  4202088-4203790
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="14"
                     /map="14"
     gene            1..3009
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="fascin actin-bundling protein 1"
                     /db_xref="CGNC:14444"
                     /db_xref="GeneID:416485"
     exon            1..859
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1509
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="fascin homolog 1, actin-bundling protein"
                     /codon_start=1
                     /product="fascin"
                     /protein_id="NP_001171603.1"
                     /db_xref="CGNC:14444"
                     /db_xref="GeneID:416485"
                     /translation="

MTANGTAEPVQIQFGLINCGNKYLTAEAFGFKVNASAASMKKKQIWTLEQDGEDSSAVLLKSHLGRYLAADKDGRVSCDSEEPGPDCRFLVVAHGDGRWSLQSEPHRRFFGGTEDRLSCFAPSVSPAEKWSVHLAMHPQANLYSLARKRYAHLGPRRDELAVDRDVPWGVDALITLLFVEQRYSLQSCDHRLLRADGRLVPSAEPGTAFTLEFRCGKVAFRDGEGRYLAPSGPSGTLKAGKSSKVGKDELFALEQSCPQVVLRAGNDRNVSTRQGMDLSANQDEEGDQETYQLEINKDTKKCAFRTYTGKYWTLTSNGGIQSTASTKNASCYFDIEWCDKRITLRAANGKYVTAKKNGQLAASMETAGETEHFVMKLINRPIIVLRGEHGFIGCRKVTGTLDSNRSSYDVFQLEFNDGAYNIKDTTGKYWMVGSESSVTSSSDTPVDFFFEFCDYNKVAIKINGKYLKGDHAGVLKASADAIDASTLWEY"

     misc_feature    67..444
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="first fascin-like domain, beta-trefoil fold, found
                     in fascin and similar proteins; Region:
                     beta-trefoil_FSCN1_rpt1; cd23344"
                     /db_xref="CDD:467452"
     misc_feature    order(67..69,76..78,82..84,178..180,184..186,208..210,
                     214..216,307..309,331..333,337..339,430..432)
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:467452"
     misc_feature    order(154..162,169..171,439..441)
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="putative actin-binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:467452"
     misc_feature    445..801
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="second fascin-like domain, beta-trefoil fold, found
                     in fascin and similar proteins; Region:
                     beta-trefoil_FSCN1_rpt2; cd23348"
                     /db_xref="CDD:467456"
     misc_feature    667..681
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:467456"
     misc_feature    805..1173
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="third fascin-like domain, beta-trefoil fold, found
                     in fascin and similar proteins; Region:
                     beta-trefoil_FSCN1_rpt3; cd23352"
                     /db_xref="CDD:467460"
     misc_feature    order(1051..1053,1159..1173)
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="putative actin-binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:467460"
     misc_feature    1174..1506
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="fourth fascin-like domain, beta-trefoil fold, found
                     in fascin and similar proteins; Region:
                     beta-trefoil_FSCN1_rpt4; cd23356"
                     /db_xref="CDD:467464"
     misc_feature    order(1174..1179,1273..1275,1279..1281,1288..1290,
                     1294..1296,1381..1386)
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="putative actin-binding site 2 [polypeptide
                     binding]; other site"
                     /db_xref="CDD:467464"
     misc_feature    1192..1206
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /note="putative actin-binding site 1 [polypeptide
                     binding]; other site"
                     /db_xref="CDD:467464"
     exon            860..1016
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1138
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1306
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..3009
                     /gene="FSCN1"
                     /gene_synonym="fascin"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggcggcggcagcgcggagcggagccgaagtgccacgatgacggcgaacggaacggcggagccggtgcagatccagttcgggctgatcaactgcggcaacaagtacctgacggcggaggcgttcggcttcaaggtgaacgcgtcggccgccagcatgaagaagaagcagatctggacgttggagcaggacggggaggattccagcgcggtgctgctcaagagccacctgggccgctacctggcggccgacaaagacggccgcgtgagctgcgacagcgaggagccgggccccgactgccgcttcctggtggtggcccacggcgacgggcggtggtcgctgcagtccgagccgcaccgccgcttcttcggcggcaccgaggaccgcctgtcgtgcttcgccccgtccgtgtcccccgccgagaagtggagcgtgcacctggccatgcacccccaggccaacctctacagcctggcccgcaagcgctacgcgcacctggggccgcgccgcgacgagctggccgtggaccgcgacgtgccgtggggcgtggacgcgctcatcacgctgctcttcgtggagcagcgctacagcctgcagagctgcgaccaccgcctgctgcgggccgacggccgcctggtgccctccgccgagcccggcaccgccttcacgctggagttccgctgcgggaaagtggcgttccgcgacggggagggccgctacctggcgccgtcggggcccagcgggacgctgaaggcggggaagagcagtaaggtggggaaggatgagctgttcgcgctggagcagagctgcccgcaggtcgtgctgcgcgctgggaacgaccggaacgtgtccacccggcaagggatggacctgtcggccaaccaggacgaggagggcgaccaggagacctaccagctggagatcaacaaggacaccaagaaatgtgccttccgcacctacacgggcaagtactggaccctcacctccaacgggggcatccagtccaccgcctccacaaagaacgccagctgctacttcgacatcgagtggtgtgataagcgcatcaccctgcgggccgccaacggcaaatacgtgacggcaaagaagaacgggcagctggcagcctccatggagacagcaggtgagacggagcactttgtgatgaagctgatcaacagacccatcatcgtgctgcgtggagagcacggcttcattggctgccggaaggtgaccggcaccttggactccaaccgctcctcctacgacgtcttccagttggagttcaatgatggagcctacaacatcaaggataccactgggaagtactggatggtgggcagcgagtcgtccgttaccagcagcagcgatacgcccgtggacttcttttttgagttctgcgactataacaaagtggccatcaaaatcaatggcaaatacctgaagggtgaccacgccggggtcctcaaggcatccgccgacgccatcgacgcctccaccctctgggaatattaatgcactttagcgtacctcccattgccaacctctttccctgtctgtttggtttggttgggtttggttttttggggttttgttttgttttgttttgtttttttggtttaatttctcctctctgtacaaggatttccagcctggcttgccctccctgtagagcccagtgcgtggtgttggaggtggtctcccttcatctcattaggaactggatcagtcgcccagcagtgcggtgcagcctatcattccaaaggggtatttccccccttctctgctcgggggctgccgtgcccagcctggccccgagcatcacctcggtccttctatttccccttcccctattggaaaaaaagaaacgacgacaacaataagaaggaatagggtcaccctctgtgctctcctctgccatgcccccactctgtgccaccgaggtccccgtggggctgtgcccctgttcctgtccccagcagcaggtctgtgccccactgaggggacaggaggacagggtgggggcacgcagcccccattccctccccattgctgggcacgggcaccagctggcagcaaacccgcggacgtcggtttgcagaacagacaagttccttggcaaactttgcacagtgagatttgctctgtacttattgcttgggtttttggggtatttttttgttttttgttttgttttttttttcctcattgaatactggaacggtgatgccaatcactgagcgcccattgctgggctgggggggctcctgtgggttgctgggggctcctgggctgtggccgcgtgccacctcctgactggaaacggaaagaaaaaaaaggaatgatgaccaaaacagtatttttgttaagtctctatttatatacgctctgggcagctctgtgttccatactgagtggaacgacgccggtgatgcccggctgttcctgggggcgtcggggcgctccatcctttgggctgcggacaccgcagcgccttccacccccagccccaacccgagggcgccgtgccataacccggggctctgcagccttaaagccctgcggtccctccggcagggtttggtgctacgctcccaccgccccatccccagtatggggacaccgcctcggctccagcgcccgccgcctcccgaggaacaaatggagccctggcgcacactttgctgccttcgtgcccgccgtgtcccctccgtgtccccccgccccgctctgcccctgtgtgacttcagctcctcacctcccgtctcctctcctcgggtgtttgtgaccctccgtaagcatctcactctgacatttaagtcttgggggggtgggggtggggtttgttcgttttggggtgttggttttagtacttttttttttttttctccttttaattattattatgtttttgtttttgttttttttttgtaagtgccatttgtataacttaaacaacaacgaaaaatagcttcaactggagaaaggtgaataataaaaaaagcaagacctgca

//