2024-11-15 19:40:20, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_023633491 15513 bp mRNA linear MAM 07-AUG-2024 DEFINITION PREDICTED: Equus caballus argonaute RISC catalytic component 3 (AGO3), transcript variant X2, mRNA. ACCESSION XM_023633491 VERSION XM_023633491.1 DBLINK BioProject: PRJNA19129 KEYWORDS RefSeq. SOURCE Equus caballus (horse) ORGANISM Equus caballus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_009145.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_002863925.1-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 08/01/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..15513 /organism="Equus caballus" /mol_type="mRNA" /isolate="Twilight" /db_xref="taxon:9796" /chromosome="2" /sex="female" /breed="thoroughbred" gene 1..15513 /gene="AGO3" /note="argonaute RISC catalytic component 3; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 4 ESTs, 4 Proteins, and 100% coverage of the annotated genomic feature by RNAseq alignments, including 113 samples with support for all annotated introns" /db_xref="GeneID:100069387" CDS 152..2593 /gene="AGO3" /codon_start=1 /product="protein argonaute-3 isoform X2" /protein_id="XP_023489259.1" /db_xref="GeneID:100069387" /translation="
MMESKDLVPECRKWWLREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"
misc_feature 227..511 /gene="AGO3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 539..691 /gene="AGO3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 692..1054 /gene="AGO3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(848..850,893..895,935..937,947..949,1001..1003, 1022..1024,1028..1030) /gene="AGO3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1187..2464 /gene="AGO3" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1598..1600,1610..1612,1646..1657,1664..1666, 1688..1690,1697..1699,1709..1711,1721..1723) /gene="AGO3" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(1802..1804,1808..1810,2018..2020,2432..2434) /gene="AGO3" /note="active site" /db_xref="CDD:240015" ORIGIN
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ataattcgaaacaccaaatgctgaatcctatcactgtgtacttaggggccaggctttggatttgattgtcattttaattccttgaagactatgtaattatgatgagcagaggcaaataaagtttttaaacaaaagtgctttttttcggtatttaaagtttagtagtaaattttctactttcagttaaattatcttcaaaaaaattactacaaaaaacttagggttgagatcaagaagcttgaagaagccgctttttaagcagttcaatcacttacaatgttttatgttaaagaagttgtcataattctttctgagccaaactgtcactagaatgtcctgtgacagaaccactcttcttttttctgccattctgcatattggaagcgttctatgttgtatttgttttcaatccttgatttaaaaaaataattaatggttttagcgttgcttagcttcagtttgaagtgtaactttcactaataactgcaataaaaaggaaagctttgctccaaa
//
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@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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