LOCUS       XM_020633535           10430 bp    mRNA    linear   VRT 24-JUN-2024
DEFINITION  PREDICTED: Labrus bergylta argonaute RISC catalytic component 3a
            (ago3a), transcript variant X2, mRNA.
ACCESSION   XM_020633535
VERSION     XM_020633535.3
DBLINK      BioProject: PRJNA1126594
KEYWORDS    RefSeq.
SOURCE      Labrus bergylta (ballan wrasse)
  ORGANISM  Labrus bergylta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Eupercaria; Labriformes; Labridae; Labrus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_089202) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jun 24, 2024 this sequence version replaced XM_020633535.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963930695.1-RS_2024_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/21/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10430
                     /organism="Labrus bergylta"
                     /mol_type="mRNA"
                     /db_xref="taxon:56723"
                     /chromosome="8"
     gene            1..10430
                     /gene="ago3a"
                     /note="argonaute RISC catalytic component 3a; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 45 Proteins"
                     /db_xref="GeneID:109983707"
     CDS             149..2731
                     /gene="ago3a"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X2"
                     /protein_id="XP_020489191.1"
                     /db_xref="GeneID:109983707"
                     /translation="

MEIGTPAAVGAQSLFSMPRRPGYGTMGKPIKLLANCFQVEIPKMDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVAPAGVDLDVTLPGEGGKDRPFKVSIKFVSLVSWHMLHEVLTGRSMPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAHYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA"

     misc_feature    365..649
                     /gene="ago3a"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    677..829
                     /gene="ago3a"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    830..1192
                     /gene="ago3a"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(986..988,1031..1033,1073..1075,1085..1087,
                     1139..1141,1160..1162,1166..1168)
                     /gene="ago3a"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1325..2602
                     /gene="ago3a"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1736..1738,1748..1750,1784..1795,1802..1804,
                     1826..1828,1835..1837,1847..1849,1859..1861)
                     /gene="ago3a"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1940..1942,1946..1948,2156..2158,2570..2572)
                     /gene="ago3a"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      10430
                     /gene="ago3a"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

tcccccctccctatttgacagcttgtgaggagtctagtgcgctgcagaggcggcgcactgccgaaggagacaccggactgaacggaggaagagtcccgaaaggtttgacaactgtgatccgggtagtgaaccgggcaggacctcatgaatggaaatcggaactccagccgccgttggggctcagtccctgttctccatgccacggcggcccggctatggcaccatggggaagcccatcaagctgctggccaactgcttccaggtggagatccccaagatggacgtctacctctatgaggtggacatcaagcctgacaagtgtccgcgacgagtcaacagggaggtggttgactcgatggtgcagcactttaaggtgaccatctttggggatcgcaggccagtctacgatggaaagaggagcctgtacacggccaacccgctgcctgtggcacctgcaggggtggaccttgatgtcactctaccgggggagggagggaaagatcggcccttcaaagtttccatcaagtttgtgtctctggtcagctggcacatgctccacgaggtgctgaccggccgcagcatgcctgagcctctggagctggacaaacccatcagcaccaaccccgtgcacgcagtggacgtggtgctgcgacacctaccctccatgaagtacactccagtcggtcggtccttcttctcggctcctgagggctacgaccatcccctgggaggtgggagggaggtttggttcggctttcatcaatctgtgcgccctgccatgtggaagatgatgctaaatattgacgtgtctgccaccgccttctacaaggcccagccagtcattcagttcatgtgtgaagtgctggacatccacaacatagacgagcagcctcggcctctcacagactcacaccgggtcaaattcaccaaagaaatcaaaggtttgaaggtggaggtgacgcactgtggaaccatgcggaggaagtaccgtgtctgcaacgtgacccgccggcctgctagccatcaaacgttccccctacagttggaaaatggtcagactgtagagcgtactgtagcccactacttcagggagaagtacaacctgcagcttaagtaccctcacttgccctgtctgcaggtgggccaggagcaaaagcacacctatctgcctctggaggtttgtaacattgtagctggtcaaaggtgcatcaagaagctgacagataatcagacctccactatgatcaaagccacagctcgctccgcacccgacaggcaggaggagatcagcaggctggtgcgcagtgccaactacgaggcagacccattcgtgcaggagttccagttcaaagtgcgtgacgagatggcccacgtgacggggcgagtgctacccgcccccatgctgcagtacggcggcaggaaccgcaccgtggccacgcccagccacggggtgtgggacatgagggggaagcagttccacaccggggtggagatcaagatgtgggccatcgcctgcttcgccacacagcggcagtgtcgggaagaaatccttaagggtttcacagaccagctgcgcaagatctcaaaggatgctgggatgcccatccagggccaaccatgtttctgtaaatacgcccagggagcggacagcgtggagcccatgttcaggcacctgaagaacacctacgccgggctgcagctcatcatcgtcatcctgccgggaaagactcccgtctacgccgaggtgaagcgtgtgggcgacaccctcctgggcatggccacgcagtgtgtgcaggtgaagaacgtggtgaagacgtcccctcagaccctctccaacctctgcctcaagatcaacgtgaagctgggaggcatcaacaacatcctggtgcctcatcaacgaccatcagtgtttcagcagccagttatcttcttgggcgcagacgtcacacatccgcccgctggtgacgggaagaagccttcgattgcagcagtggttggcagtatggacgcccaccccagcaggtactgtgccactgtgcgggtccagaggccgaggcaggaggtgatccaggacctggcctccatggtgcgggagctcctcatccagttctacaagtcaacccgctacaagcccacccggatcattttctacagggacggagtttcagagggccagttcagacaggtgctgtattatgagctgctggccatccgtgaggcctgtataagcctagagaaggagtaccagcccggcatcacctatattgttgtgcaaaaacgccaccacacacgcctcttctgtgccgaccgcaacgagagagttggacgcagtggaaacattcctgctggtactacagtggatacggacatcacgcatccctacgagtttgacttttacctctgcagtcacgctggaatacagggcaccagtcggccctcccactaccacgttctgtgggacgacaattgttttaccgctgacgagttccagctgctcacctaccagttgtgccacacttacgtgcgctgtacccgctcagtctccatccctgcgcctgcctactacgcccacctggtggccttccgcgcccgctaccatctggtagacaaagaacacgacagcgctgagggcagccatgtttctggtcagagtaacggtcgggacccccaggcgctggccaaagctgttcagattcaccatgacaccctgaggaccatgtacttcgcctgagctacaccaacccctctccaaaccattgccacattttacacacacaagaaaacaaaatacacactgacacaactgtgcacgcctggcttgccagtcaaagagtcctcataggtgcaagtcccccaacccaacacacacacacacacacacacacacacacacacacacacacgcctagtcaatccggacctgacactgtgcagaggagagcagggaggaacgaggggaggacgcacccccacactggactgaggatgcaaaagctgctttaaatacaaacaagacagaaactcagcactattatgcaatatttaaccagccaaccagtttgttttctccctcatcaggccccctttgttttaccccttccctctgtttctcccccgtttgtctcctttacttatggcctgatggttgttctgtttttattttattttcccttttcttttagctcaatctcctttgccatctacagtacctcaagtcagtcagagcagcagcacttttacattctgccagttaaactgtcgtttgtcgaatctccccggtgttagaaacgagaagagagcgtaaaggaagggtcttcgtctgaagatgtttcatgttagatttatgttgtgttttttattctatcggactcgagtcgtccaagctaccacttttattgtccccttttcatctatttttttctctgttctgtcacattatagtgtgtgaaagcaagagtttactttgagcacactgccacctgttggcgacgaggtatacatgcgcccttaaaatcacaacaaagagttacacaatcagttgtgattgaactaaaacagtcggctgtctcattgaaacagagtcaccccatagtggctgatgtatcaattactctacagtatgtatttcatttaaagtataacactgttatttaattcagtttttttttcttctacattatgtgaaacattttatgatttttttgattaatcatttaaaccatgcaagcttattttttattctcatttattattagtctgcatgcttttatcccccctctgtgctttttatcacatttccctctgttgtgtttgagatggtgggtaaatcgagatcacgtcgacggtttcctctagtgcaataatcaggcgaaacgaagggaggaggattgtaggggactttgaaagaacagtttggcccaagagtttgggcgctttcatgaattgctcctctgtgagacgattgatcagcgcgttgtacgatattgtccttgccgttgggcaaaaaaaacaaaaaaaaaacaacaaccctgcagttctcatgtttttacttgaattgaaaggatgttatggacctctgtggttggaggagacttttactatcaccaggtgttatttccgaggtttgaggctgattttcttcattcttgagaataatgaagcttctcatgtaactgcagcaaagtggagagaaaaaacaaaaaggccataaagagatagtattcaagtgcctggtggaggttaagtgttcagtggttaaaagtaaataactattggagcctatgtcagcggggttaaataaccaagaagcatattccaataaatggacagcataagaggttttgaaagttcacccgatgcctcttgttcctctcaacaactgtctactgacttttctaaacatctcattcaatcgtcctacaatcactgtgtgtgttgtgttcgcctatacagcagtgttagctgtgttagtggctttgccgagttgtctttttgcctaatcttagccagacatggatccagctgctacagtgcgctcgtacctaaaaaatgacggggggggggggggggggtttccatgggtaatggagtcagccttgtcaacattatgagtctttcaataatcagtttcatttgtcgtggacaaggtttactccctgcccgtgaaaccgtctgagagttgactccagattcgagcggaggaattcagcaagtggccgatatgtgacgatatgaaaacgtgtatctggattgtgttcggccacttggctcctctgtgctgctgaagcttgtttcggagggggagggtttttttagtaagtaatctgcactaaaagaagctgtgtttagggcgtgaacacaggcgtggtgctactctgtctgaagctgaacctttatgtgaaactcgagatgagcaggtgggaaaaggtagaagatgacaaaaagcctcacttacataaaggcaggagaaggtgctgtggtcagtgcagggggggggggggggggggagctctagattgagggatttcactctgtagtgatcagaaataatgtagaaatggtacacatgtggacgtgccccccctcggaggacttagggtcctgcacttggactgcctttcattggccagtgggtttgagccttcatgatttcactcgtgtctgaaagcctttataaataaaaaaaaaaagccagatgaaagtatatttgtacattttaaattatctaatgcacaccacttatttttgctaacagaattgaaaaaaaaaagtagtctaaaaaaatattaatcttagtaaaaacatgtatcctgataagtaaaaaaaaaaaagtgtaataacaaagttttattatcgcaatagactgttgacttgttcctgtgtcactgtggtgttacgtgtgaacagtggtggggttgtcgtgtttggactgtcaaactgttaccgatcgggatgtttggataaaaaaaaactgcgagatgttgacagttatttctcttcttttttttattttggtggatggtcatactgttggaggtttgttgtcgaggagagaggaaatatcacaaactgcactgcaggaggctttttgtatttagaaacaacatgttaagtgtcgacaggagaagacgaatagttaatgtatcgagctcctgctcttgaatgttttcttcaaatggtgctgatgcctgctccttatcacgcctgaaaaaggaacgggcgagtgactttttcaaagtggttgtccatcgtccttgaggacacgtttgatcaaacaatgtcctaacaaggggtggtagttctccatttcttttcccctttgtgttaaatcctcggtggggggattttacctccggattgcaacctctgttgcttcctcagactccgagtcacttcatgtcctcgcaaaacacaaagactcagcctcccggtaaatctgcagtgtgacaaagcctgtaatcttattgttgctcgctttcctcttttgctcccaaacatttactcccaatgtgccagaggagtacattccatggctgtacaatcccccccccctctcccagggaggcaaagactgattaaaagctgaaggacaatagtgtggtctggtcagtgagataaagtcgatttagttcattcaaggatgtgtgattttagaaggaatataagctgactgatgaatattttgtggcaggttgtgttgaaagtgttgatggttgagtgtaaagaattgactccattaataactcactctgctgtctgtaatggatgttcagtatgtgtatgaactacactctcgagggccgttgaacacatgtttacatagcagatgtgtttgcctcgcgcacagctgaaatgtcatgagctctgctttgcaaatattcgcttgtagtgacgtgacctaacacgagagcgaccattcagggtctgtggcagtgagcgctcggagggaagacgtaatgtatgtgtctcgttttttctctctttgttatacagccggggaatagatttgtttgtttttccaattctattaaaaaagacttgtttgagttgactgaaatgaaaaggacacacatagcttgcggctagctgcgacctttggctctcaattaggatagctaacagtaaagacaagtctttttttcttttttctttttttctttttttttacagaagctggaaaaacaaaacattttatccagaaagtgacggagactggtgctgacaaatcgccaaattaccttttgaaaggtcagtgtcctgatttcaaacgagttaaggtgtatttcattttgagaaatggatcaataaatctcagatttgagttgcagtggaaggtagcaatggagtgagaaaaagtccacagaaagtgcctttcctcttgatggtgctgtaaactgaaagataaaaacaaaatctccttttcaagaacatattgcagtgcaggaacggctgcatctacacactcttttttttttttttgttagagagatggcaatgcaaactcgtgttcgttgtttttagaattaaagtctacagataaataatagatttaaaaaaaaaaaagccaagtatatggttgtggttgagctttcgcttcctagtgcattcagtgtcttggaccaatggtgtcgatggtagagtgaaatgtgtgtgagatagagtgggtggtttgagaggtttgttggggttcgttttagaagacactagggtgacacggccctgcccaagaatgacaaacatagcacagcactttacagactgccactcccactcagacacaatccctccaattcctgatctcctcctcttaaaccagggggacgagaggatgccaacctcgatgaaaacgaggagtcgaaagggactcgcgtgttaccaaacagaagcggcccgttgttcaaagtgtgcctcatgctcttgtgactttgtcagcggctcgcttgccttcgggtggaggtattccctccggttaactctgctggacatgtatttacagcttgggctgggtgtcaaaacatgatatcggtgcctcccgattaaaaaatgtaggaggcttacatttttttgaaaagtcttgaatttttttactgaagtatattctggctgaagtatcaagattttctccttgaagggcattttaagaataaaattgatgagttgttctgataatgatactagtgacaatatctcattccaccaaaaataccgtatctgtatcctcttctctcaaaactcaagtaattttaataatttatcaagcagcaacagtgcagcgctagcagagagtgtaatgctactgaaagctatctgtgttttttaatcacactggtatctgaggggttctcgggtatcagatgatacttaggtctagttatcggaaaggaaaacctggtattggaacatttgtattagttttatcggttaaataaaacacaaccagagtcagtatttaaagtgttcccatgacgcccagccccagcagcagcagcccctttctcatcttagtgccctgccttgtgtcctgcctctgatggagggaaaatgtgtcccagcagtcctgagcagggagggtgacgactgaaaagtttgaagggtggtctgtagttctgtgggtacctttacagtccaggggatggggatggggatggggaggggggagggggggggggggtgtaatctttacaaacactgcacctcacttaccttggtatgctgcatctgttatacttcatgaaagaaaaaaaaaaccctgcaaactgcttttattatgacatataatgcttgagtaatgcctgattgcgatattcttatacagtaactattttagagtggaataagtataactgtaaaaaaaaatattctgtttttgtcttaacacttatctgaatttgacgaaatgttcttgagccgacttttgtttttttgttttgttgtcctatttaaatgtgttgtttctttcaaatttatataagaaatatattatgtgcggaatattttatggtgtatttattgagagtgtgcgttcaagcggctggagtctccgcatcgtatcgcagcatggtgggggcggagccgggagtgaaacgaggcctttagcccctccccctccatgatgacgccttattctcttagacacgcaagcacaacaatatggagggggaagcgaggtggacgaaaaggacaaggagggtttgacctggtgattcagagctgtgtatcatgtttttttttttttttttgatatttgcaggtcaaatcttcctcgtccttttctcaatattcttttaaccctccagttttttattttttctttaaccaactttacaaggccaaacgctaacccccacaagttgcagctgacctctgacgaagggacccatttctgaaccacgctgactgaagtgtccgatagctgagtttgggtttttttttcgtcgcgagctgctaattggtacgatagccatgtcaattcccagagccagtcgagagcaggtgggaaagcaagaattcaaaacatcttcggatcctggtgtaaatctgaacacacgtgttgcgttttttctttcctctttcaactcgtcaagtttagttcttcttgtgccagaacacctcacagcagttcaaaaggtctcattccacaaacacagaagacatgcctcaaccttaagtgcgttcttacacattattcagatttctgtgtgactttgcgatgcccgtgtttagtcgcctaccatgaaaacaagctaacgaacataccggtatcttcatctcttctttttttttatttttattttgtcatgtaaaccactacttttgctacaggattgtaatgtaccaacatgtgtaggctttttgaagaaatgactctgtcctgtttggaacgaggtcgggggtcaaacagcatttgaaaaaaattcttggcatttacaaaaaaaaaaaaaaaaaaaaaaaaaaatcagcaaacacaaaaatgtggaagaggtcaaaactgttgatgacttcaaaatcaaaagctggttcttgttttatttctatggagcccctggagggacatggagggtaaaaatgaagattaatcccaagaaagatttaacgatgcaaagagacaattgcaagaagttctctccgtgtctctctgtgggctccatgtttttccactgatggcaaatccaaagagcagtattttcagatacagtttgacccgggtgctggattacagagacctgtgcctgtataatgaaccaaggatgagttctattgtcatgaatttcattcctttttttttttaagctgttttcattggttgtccctcacccaatcagaggaccagagacatggagcttttgagtgttgtccctcctgttacaaagttgaaataaaaagggccctctgtcctcgtctatcgacgtttactgtaatgtttacccccacggctaccactcgtttaacctgttttcatgccattatcattccaataatgactctgaaccaaaaattgcacaagagattaggctcctgacgccgtgttattcacatgatggttttgaagacagatactcgacagtggccgaggatttaacacctgtgtgcgctgattgtcagattggatttccatgtagcatctcactcttttgtttcagttttatttcaaagtaaaaatctcgggctctgatacctccgagcgaggcaccagcaaacaggtgtactatgtacacgtagaacagtgagccttctccgcaccagtcgatccatgtctcagtctctctctgtgctgcgaagcctctgttgtaccaacagctctactcctctacgcttgaatgtgtctttctttttgtaactctctctcataggtttgttggccttttagtgttgctttgcttcagtttggagtgtatctttgactaatacttgcaataaaatgctttgcttta

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