LOCUS       XM_019957858            7884 bp    mRNA    linear   MAM 12-JAN-2017
DEFINITION  PREDICTED: Bos indicus protein argonaute-1 (LOC109556512),
            transcript variant X2, mRNA.
ACCESSION   XM_019957858
VERSION     XM_019957858.1
DBLINK      BioProject: PRJNA360096
KEYWORDS    RefSeq.
SOURCE      Bos indicus (Bos taurus indicus)
  ORGANISM  Bos indicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_032652.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Bos indicus Annotation Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7884
                     /organism="Bos indicus"
                     /mol_type="mRNA"
                     /isolate="QUIL7308"
                     /db_xref="taxon:9915"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="peripheral blood mononuclear cells"
                     /geo_loc_name="Brazil"
                     /breed="Nelore"
                     /note="animal owned by Agropecuaria Quilombo Inc."
     gene            1..7884
                     /gene="LOC109556512"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 71 ESTs, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 66 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:109556512"
     CDS             132..2012
                     /gene="LOC109556512"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X2"
                     /protein_id="XP_019813417.1"
                     /db_xref="GeneID:109556512"
                     /translation="

MCEVLDIRNIDEQPKALTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    132..473
                     /gene="LOC109556512"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(267..269,312..314,354..356,366..368,420..422,
                     441..443,447..449)
                     /gene="LOC109556512"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    606..1883
                     /gene="LOC109556512"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1017..1019,1029..1031,1065..1076,1083..1085,
                     1107..1109,1116..1118,1128..1130,1140..1142)
                     /gene="LOC109556512"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1221..1223,1227..1229,1437..1439,1851..1853)
                     /gene="LOC109556512"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

tgaagccttggtcagtggccagatccctgttcccctggagtctgtacaagccctggatgtagccatgaggcacctggcatccatgagtctcagccactgccttctacaaggcacagccagtgattgagttcatgtgtgaggtgctcgacatcaggaacatagatgagcagcccaaagccctcacggactctcagcgtgtgcgcttcaccaaggagatcaagggcctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgcgtgtgtaatgttacccgccgccctgccagccatcagacgtttcctctgcagctggagagtggacagactgtggagtgcacagtggcccagtatttcaagcagaaatataacctgcagctcaagtatccccacctgccttgcctgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagctgactgacaaccagacttcaaccatgataaaggctacagctagatcggccccagacagacaagaggagattagccgcctgatgaagaatgccagctacaacctagatccgtacatccaggaatttgggatcaaggtgaaggatgacatgacggaggtgacgggacgagtgctgccggcgcccatcttgcagtatggcggccggaaccgggccattgccacacccaatcagggtgtctgggacatgcgggggaaacagttctacaatggcattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaagtgctcaagaacttcacggaccagctgcggaagatttccaaggacgcagggatgcccatccagggccagccttgcttctgcaaatacgcacagggggcagacagtgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgcccgggaagacgccagtgtatgctgaagtgaaacgtgttggagatactctgttgggaatggctacacagtgtgtgcaagtgaagaacgtggtcaagacctcgcctcagactctgtctaacctttgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgcagtctttcaacaaccagtgatattcctgggagcagatgttacacacccaccagcaggggatgggaaaaaaccctctatcacagcagtggtaggcagcatggatgcccaccccagccgttactgtgctactgtgcgggtacagcgaccacggcaggagatcattgaagacttatcctacatggtacgtgagctgctcatccagttctacaagtccacgcgcttcaagcctacccgcatcatcttctaccgagatggggttcctgaaggccagcttccccagatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcccggaatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttacgtacgatgcacacgctccgtctcaattccagcacctgcctactatgcccgcttggtggctttccgggcacgataccacctagtggacaaagagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgccgcccaaatccagaggaagcagggaggagggaggtggggtagggaggaatgcagaaaggccctgtttccttctgcagagggggcaaaagcgggggggaacagggccagtaagccagaccaccagccagaaatctctgatattcacctcatgccctcaacccctcaccccatcttgtcacatctggccctgaacccactggaccaagacaggcagcagcggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaaagactcacgcctgacagcttggtaaggtcggctctgcagccctgcggacaaaagctggtaggtttgggtttgatactttagatggaaaagtgaggggcttgagaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaacgaaatcagatgcagatcaatattttaggatactagatgttttaatgggttgagaatccagcctgtaggaagatttttaatgctaatgattttggttgccccctcccccagctgccactcccctttcccttattcctctttctccaccttttctaccccaccttacacctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaatggtaatgctgcagaactgcaaccttttgtaccttttggggggtgggggcggggtgggggtgggagaggaggtaggttgggatgaaataccctgtacccaacaggcctccagccagagcgccagctattttgcattagaaggaattgacttccatattcattgagcttttaaaaagatcacgacctcaagatggttaaaatccattgacatttgcactttcagacatgacaagtctaggagctgctgagatgactggcccctggcctttccacttatgtctcctttcttcttgtccccgctttcttcccacctgcctgggtctggagttaactttcatagcatttcccactcttggcttcttttccctgatggtcaagcctctttatgtttcaatattttttaactggggtgacttacaacagatgatctttaggtctaaaataagggggaaaaaaagcaaaaactaaacattatttttatactataacctgagtccattgccaaaatctggaactaaatccctcccatgcccagtgagtttacatcccagaaacattgagccatcaaaggaactatgtacctgacttctttggcctgctttggcttggctctgtagggtgtggttatctccacacgtggggctcaggctccaccctttgtgcaaataatacctttctcttgctgcaggcacctctgctgcactgccctgcactcttcctgcaagtgcatctcctcctctggactatcctctgatgcttggcttatcccagatttcagcgtgtcctgtggataggctgggggattttgctgctccctattgcttctgtttacacaaatgactttttcctgatttcccactagggcatgtgagtggatggcatgggctttttttttctcgttttttcctgtcttcctgggtagagatgggatttggctgtcttgcagaactggaaaagtagggggttctagcttggggcctgttggccttgaagcaaggcttcctctttcctcgactgttccttttttcctgtcccactgcttgggatgaggagttgcagcttcagtgtggaaattcctctttttgaggagcccgggcttgggtttaccccaatctggtgatgaagccatgactcttcagacctagctcaggctcaaggccagccagcagaaggctggtctgaatatgggcctatgcagtagagctaccatttcccctccccagcagcgcttgtacagacccagatttgctatgcaaaacagtctatcccaggttctgttctggttggctactttgttcagcaacttcacaaaacgtagcacaaacattatggagaaggcatcaggactgttgagtaactctttctttacttctttcctactggcaacagtatggggtgccctgtgggcacagcccagctgaaaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaagagtgatgccaacactcccatctgccctgtccatcgccttcatatattgtctacttcgtgtttagtcaccctttagggaggggagctctcttgggacagtgggctctgagggttctcttctcgggtgcgttttggggctgggatcagggcagtattcctggaaggtccagtcattcaccagcatttgcaaatgtccattgagagctggtggtagccacctactctcagcaacaagtttgtgttctctcctttttctctctttgcctcactctctccagttgggtcttgagctgaggcttggcattttttagcccttaggcatttacatgccatttaataaataaaagaaacagcttgggcaatggcaagaacatgacatcttgctgtgattttctttttttctttctttttatctttgagacttgaaaaacacccttaaccttgaggattcttcttcttcgaaaggtggtgcatgcagattgagaagtggtgttggcaacaagcttggctttctttgatttggttaaagtggtgcttcttacttaggctcagaggaagtgctggggagaccccagcctcatcctcttagacaagtctcctggtccctttgttctactcttttgccttccttttcctactctctctttccctggcctcgttttatttttttctgttcattcagcttgcttgctggcctgcctatctgcctatgtgatgatgaattctctgcatggctacaatgatcccactgttagctggcaaggtcaggcttagctctttggctgcagaagaccaagaatctgcttcccaagcctagtgatgtccttcctgggttggaccgccctcaaacttatgtgaaggtgtagcagaaggcctgcccatctggcatgaaatcaggaaggcttctggcaacttccacatctgtccactctttggagtcggcttctcttgttgctttttctagatctggtttcatttctctctacctggggcttcccttttctgaggatgtcctagcattgacctttttggctatccagggttgaagggttaggggatagacatgggggaaggagggatgggaagagaatggagagaatttggctaaaacatgggaaaggagagmgccctgctcactgatcacttttccagtccagcctgactcattggggccgaggtgctacggctggcctctggggataagcatgaggctgttgttgctgggaacttaggattaaattaatgttgaaaaagaaggtaactaaaagtgtgaaacctccctaaaaagctcctggttcccgtctactcagtatctcctctatagcctcctctttggctaagcaatgatgttttttggatagttttctttttcttgtccagaattctgtaaatgaggccagcaagatgggcagccaaggggatgcagtgatttctcagctgacccataggatatctgcaaggctagtgggacagtgttttagacttggcattatgtgtaacaaagaaaggtgaatggtccttccccttcagggtagaaagtcatttcaaactgactaagatgcagttttggaaactacatcagggggaagttatttttatttatatttgctgggccacggccaatcctggatggtagctgggatgccttccttcttaaagtctgatcatggcagggttatgcagggcactctttcctctttggccttctaagctgatcagggagaagggattctctggttttctcttctctcccatttattaggacttgccttctccctgggcagggagagaggctaggttggtgctctccccttactctactcctactgacttagaacctctggctgctgttcgggagcccaagaaaggtggtggaggcaatgggctcaaaacaacaacaacaaaaccagaaaaaggtgaggaaaggcagatttccttctttaacaaggaaaataggaaaccctccaaggattgtgcaaataaagacaatgtgtcaaatgcactgactcccctggtgtagtagcaataaggaaaaatgaaatgactttcctgtgcacatagtccaacctgattggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaaatgtccctggagccccacagctgtgtacttgtttgcatttgtttccctatgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtaaaattatcccagcagctgtaatgtacagtttcttctgaagcaagcaacagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaagtgcggtctctctctctctttttttttcttagcaaagcaaaccgttggaattaattatattctggtagattttacattagaataatagattgtgagaagagcagaatcatcactttctaaaggagtaaagtgggtaaaacaaattccagagtgttgaaactgccgatcatatgtagtcatttcacagggtttccatttattcttcattcaccaaacatataaagcactgtgtctagcagttktgttggggagtaagcaggcataattcaaaaatgaggaaaacagtgtttgtctccttaaggagcttaaaaagtttggttggggatatgagtagcgaaatggttctttggtaccatttagagagattataaggattgggaagaaggctataatgctgcagcaatgaagawagaaaggaaagagcaaawagaagagaaacgcaggaggtaaaaccaaaagaactcaagggayggtggaatgagaagaaccaagtagaggctaccatccacttggckkgagcaagtgagtatgttgggacatccttcctytaagccaagawtgggggaagggagaccgtagaaggaaggtggtgaattttgtgaagaaagaccattaggcttttatagactgagttttgaggttcccaggtttccagtaaacatttatattttggtgctcagggaagactccaaaactgcagttatagatatgagattcataatcatagagatggtagttaaagccataggaatgarcaggatggcttaggaaagagtagggcaagagaaacctagtgtacaactctaggaaacgagatcaggaaatggaacctaagatgactgtcacatcactcatagatagcttatatggttttgattgatttaatggggtgggagaatagtgaggagagtggaataggattcaacagcgacatgattaacaacaggaaaactactgtggtgaagggagggtattattttctacttattttaccatccttcactccatcttctctgggatcttgtaactatatggtcatcctccgatttttcttgaaaatgagcattggaaaacctaacttaaatcaggctaagactgagacttccaagtcgttcacagtcaccaccaccactacatccacctccagcttcctcctatcctcaggagatacttgtgaaacaataaaataaacaaacctaattttgttccta

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