LOCUS       NM_001386636            1098 bp    mRNA    linear   VRT 16-SEP-2024
DEFINITION  Danio rerio NELL2 interacting cell ontogeny regulator 1 (nicol1),
            mRNA.
ACCESSION   NM_001386636 XM_021471898 XM_690005
VERSION     NM_001386636.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1098)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1098)
  AUTHORS   Aoki,M., Segawa,H., Naito,M. and Okamoto,H.
  TITLE     Identification of possible downstream genes required for the
            extension of peripheral axons in primary sensory neurons
  JOURNAL   Biochem Biophys Res Commun 445 (2), 357-362 (2014)
   PUBMED   24513284
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR318672.5.
            
            On or before Aug 28, 2020 this sequence version replaced
            XM_021471898.1, XM_690005.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQQ01002075.1, EH556775.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505383,
                                           SAMEA3505388 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               CR318672.5         100853-100980
            129-251             CR318672.5         101252-101374
            252-340             CR318672.5         102781-102869
            341-1098            CR318672.5         105750-106507
FEATURES             Location/Qualifiers
     source          1..1098
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="7"
                     /map="7"
     gene            1..1098
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /note="NELL2 interacting cell ontogeny regulator 1"
                     /db_xref="GeneID:566718"
                     /db_xref="ZFIN:ZDB-GENE-030131-7914"
     exon            1..128
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    95..97
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /note="upstream in-frame stop codon"
     exon            129..251
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..412
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /EC_number="2.3.1.17"
                     /codon_start=1
                     /product="NELL2-interacting cell ontogeny regulator 1
                     precursor"
                     /protein_id="NP_001373565.1"
                     /db_xref="GeneID:566718"
                     /db_xref="ZFIN:ZDB-GENE-030131-7914"
                     /translation="

MRPSGALAAAAVMLMLLVCCQAEDSGSVIPAESRPCVDCHAFEFMQRALQDLKKTAFNLDSRTENLVLRAEKRALCDCMPASSLR"

     sig_peptide     155..220
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
     misc_feature    215..397
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /note="Neuropeptide-like; Region: Neuropep_like;
                     pfam15161"
                     /db_xref="CDD:317565"
     exon            252..340
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /inference="alignment:Splign:2.1.0"
     exon            341..1098
                     /gene="nicol1"
                     /gene_synonym="fj40g07; si:dkeyp-75h12.5; wu:fj40g07"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atcctacggcgcaccgcgaaggacaataatcataaaaacgcgattgacgctccgcaacgaaactgcgtcctgtgaaggagggcggtggtttgactaacggtgccagtgtcttcatcagaaaactacaggtttattgtgtgtgtgcggcgacagtatgaggccaagcggagctctggcggcggcggcggtgatgctgatgctgctcgtgtgttgccaagccgaggactcaggctcggtcatcccggccgagagccggccatgtgttgactgtcatgccttcgagttcatgcagagagccttgcaagacctgaagaaaacagccttcaacttagactcacggacggagaatttggtgctgagggccgagaagagggcgttgtgtgactgcatgcctgccagcagcctgcgctaaaaagccagcgtaaacactgtcctcagatacagaaacctttatgtacctaaaggatactacctgctcttagtcaaacacactccgttgctctcaaacacgcttcctgtcatgtgtgacaagaaacatgttttatctttcatcataatatgtgcataaacacacattcctgacagaagtcaacacacaacattccactgttgaaacgtcgatgctgagaggcacattcatgatagggcagcagcaaatacattgtatcttccatataagtgaatataaacacaggggaatataaacacctctccaggcacaatgcactgcaaaagattctgcaaacacattatttattatcattatttgcacagtagactagatgtttttcttttttaaatactaacggctttttatatttttgttcttaggatatatgattattagtcacaatggttaagcagatatttagatctattaaatatatcaatggcgttgtttgctgtaagattggtagatctacgactagaagagagtctgcatgtaaagtgatagtttagagttttatatgaggatttatgagaagggaaatgaaggaatggttcatagagattactttggtactaagatgtgagttcacagctgtaacaatgtctttttgtgtgtagaaaagtgcattaaaaacatatgtgacgtca

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