LOCUS       NM_001087438            1787 bp    mRNA    linear   VRT 03-APR-2024
DEFINITION  Xenopus laevis vimentin S homeolog (vim.S), mRNA.
ACCESSION   NM_001087438
VERSION     NM_001087438.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 1787)
  AUTHORS   Yamada,A., Koyanagi,K.O. and Watanabe,H.
  TITLE     In silico and in vivo identification of the intermediate filament
            vimentin that is downregulated downstream of Brachyury during
            Xenopus embryogenesis
  JOURNAL   Gene 491 (2), 232-236 (2012)
   PUBMED   21963995
  REMARK    GeneRIF: This is the first report to demonstrate that Brachyury
            might affect the cytoskeletal structure through regulating the
            expression of an intermediate filament protein, vimentin.
REFERENCE   2  (bases 1 to 1787)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
REFERENCE   3  (bases 1 to 1787)
  AUTHORS   Herrmann,H., Fouquet,B. and Franke,W.W.
  TITLE     Expression of intermediate filament proteins during development of
            Xenopus laevis. I. cDNA clones encoding different forms of vimentin
  JOURNAL   Development 105 (2), 279-298 (1989)
   PUBMED   2806127
REFERENCE   4  (bases 1 to 1787)
  AUTHORS   Sharpe,C.R.
  TITLE     Developmental expression of a neurofilament-M and two vimentin-like
            genes in Xenopus laevis
  JOURNAL   Development 103 (2), 269-277 (1988)
   PUBMED   3224553
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC054161.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054161.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00012418, SAMD00012419
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1787
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="6S"
                     /map="6S"
     gene            1..1787
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="vimentin S homeolog"
                     /db_xref="GeneID:386600"
                     /db_xref="Xenbase:XB-GENE-6255792"
     misc_feature    26..28
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="upstream in-frame stop codon"
     CDS             56..1447
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /codon_start=1
                     /product="vimentin-4"
                     /protein_id="NP_001080907.1"
                     /db_xref="GeneID:386600"
                     /db_xref="Xenbase:XB-GENE-6255792"
                     /translation="

MATTKSSYRRIFGGNPRSSSSGSRYVTSSSRYSLGSSMRPGTSSSRMVYSTSASPAVFKSSSVRLRSSLPPARMSDSVDFTLADAVNLEFKANRTYEKAEMIELNDRFANFIDKVRFLEQQNKILVAELEQLKGKGTSRIGDLYEEEMREIRRQLDQAINEKARVEVDRDNLGDDLQRLREKLQDEMIQREEAEGNLQSFRQDVDNASLARIDLERKVESLQEEIVFLKKLHDEEIRELQLQIQESHIQVDMDVSKPDLTAALRDVRQQYENVASKNLADAEDWYKSKFADLSEAANRNNEALRQAKQDTNDYRRQIQTLTCEIDAMKGSNESYERQMREMEENFALEAANYQDTIQRLQEEIQNMKEEMSRHLREYQDLLNVKMALDIEIATYRKLLEGEESRITIPVHSFSTMSLRETNRDSHPVDTHSKRTLLIKTVETRDGQVINESSQHHDDLDLDLE"

     misc_feature    56..322
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Head"
     misc_feature    56..196
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    71..340
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="Intermediate filament head (DNA binding) region;
                     Region: Filament_head; pfam04732"
                     /db_xref="CDD:461414"
     misc_feature    323..430
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Coil 1A"
     misc_feature    344..1267
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="Intermediate filament protein; Region: Filament;
                     pfam00038"
                     /db_xref="CDD:459643"
     misc_feature    431..496
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Linker 1"
     misc_feature    497..772
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Coil 1B"
     misc_feature    773..841
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Linker 12"
     misc_feature    842..1258
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Coil 2"
     misc_feature    1088..1090
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="Stutter. /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (P24790.1); other site"
     misc_feature    1259..1444
                     /gene="vim.S"
                     /gene_synonym="vim; vim-a; vim-b; vim4"
                     /note="propagated from UniProtKB/Swiss-Prot (P24790.1);
                     Region: Tail"
ORIGIN      

gagtcctgctgaagtactagctgggtgaggacaagggagaaaccttagcaccaacatggcaacaaccaagtcatcttacagaaggattttcggggggaaccctaggtcgagctcatctggaagtcgctatgtgacttccagctctcggtactccctgggcagttccatgcgcccgggcaccagcagcagcagaatggtctattccacctctgcctcccccgccgtcttcaagtcgtcctcggtcagactgaggagcagcctccccccggccagaatgtccgactccgtggacttcaccctggcagatgccgtcaacctcgagtttaaagccaacaggacctacgagaaggcggagatgatcgaactcaacgacaggttcgccaacttcatcgacaaggtgcgattcctggagcagcagaacaagatcctggtggcggagctggagcagctgaaagggaagggcacctcgcggataggggatctctatgaggaggagatgagggagatccgccgacaattggatcaggcgatcaacgagaaagcccgagtagaagtggacagagacaacctgggcgacgacctccagcgactgagagaaaagcttcaagatgaaatgatccaaagagaagaagcagaaggcaacctgcagtcattcagacaggatgtggataatgcctctctggcacgcattgacttggagaggaaggttgagtccttacaagaagagattgttttcctgaaaaaactccatgatgaggaaatccgagaacttcagcttcaaattcaggagtcacatatccaggttgacatggatgtgtcgaaaccggatctcactgctgccctacgtgatgtccgccagcagtatgagaatgtggcttctaaaaatcttgcagatgccgaagactggtacaagtctaagtttgctgacctgtcggaagctgctaatcgcaacaatgaagctctgcgtcaggctaagcaggataccaatgactaccgcagacagatccagactctaacctgcgagattgatgcaatgaaaggatctaacgagtcttacgaacgccaaatgcgagaaatggaggagaactttgcccttgaagctgctaattatcaggacactattcaacgcctgcaagaggaaatccagaacatgaaggaggagatgtctcggcacctgagagagtaccaggatctgctcaatgttaagatggctcttgatattgagattgctacttacaggaaactcctggagggagaggagagcagaattaccattcctgtacattccttttctacaatgagcctgagagaaaccaaccgcgattctcacccagtggacactcattccaaacgcactctgctcatcaagactgtggagacaagagatggacaggttattaatgaaagctcccagcaccacgatgacctggacctggacctggagtgaaattgaaatatccggaacataaccagagaacctttaccagcaccgtaatagcgttgtgttttaaaatttgaagaaaaccagctttcaagtgccttttgcagttaattggggagcgcaagatagggataagctagctgacagttaggagtttggtttggcaaggacaggcagtgagcttccttctgtctagtttacagactatgtaatagcaattatcttgtgccgcaatactgtttttacattcccaagaagaaaaaaaagctttttttatttccaggcaatgtgcagccagtgcttcaataaatctttaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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