LOCUS       NM_001127427            3072 bp    mRNA    linear   VRT 22-DEC-2019
DEFINITION  Xenopus tropicalis PBX/knotted 1 homeobox 2 (pknox2), mRNA.
ACCESSION   NM_001127427
VERSION     NM_001127427.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 3072)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166172.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166172.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3072
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="7"
                     /map="7"
     gene            1..3072
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /note="PBX/knotted 1 homeobox 2"
                     /db_xref="GeneID:100151724"
                     /db_xref="Xenbase:XB-GENE-853128"
     misc_feature    157..159
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /note="upstream in-frame stop codon"
     CDS             169..1575
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /codon_start=1
                     /product="homeobox protein PKNOX2"
                     /protein_id="NP_001120899.1"
                     /db_xref="GeneID:100151724"
                     /db_xref="Xenbase:XB-GENE-853128"
                     /translation="

MMQHVSPAPALTMMATQSVPPPPYQESQQMTATAQQTAKPQPVHLPAASAAANPVPGAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSEDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSNSLHTQDMLQNSPNSMTGLSNNPQGIVVPASALQQGNISMTTVNSSQVVSGGALYQPVAMVTSQGQVVTQAIPQGAIQIQNAQVNLELTSLLDSEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGLPGTNPDGSVNMENLQSLSSDSLTMQQAMMAAHDDSLDGTEEEEDEEEMEEDELEDDSEELQTTNVSDLGLDHSDSLE"

     misc_feature    451..708
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /note="N-terminal of Homeobox Meis and PKNOX1; Region:
                     Meis_PKNOX_N; pfam16493"
                     /db_xref="CDD:465140"
     misc_feature    order(1033..1047,1051..1053,1111..1113,1129..1131,
                     1168..1170,1174..1179,1186..1191,1195..1203)
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(1039..1041,1048..1050,1177..1179,1186..1191,
                     1198..1200)
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    1087..1203
                     /gene="pknox2"
                     /gene_synonym="prep2"
                     /note="Homeobox KN domain; Region: Homeobox_KN; pfam05920"
                     /db_xref="CDD:428673"
ORIGIN      

ctcagatgaacagagaaccgaagtgcaagttattgtgggccacatgaacttttataatagctgcctcgtgtgccagttaaagtgaagacgtctctggaaaaaagaagtaatgtaagaaggaaaggcaatttattaagcagtaaagggctctagatgtgaatcaatcccatgatgcaacatgtgtcccctgcaccagctctgacaatgatggccacccagagtgtgcccccacccccttaccaagaaagtcagcagatgacagccacggcgcaacagactgccaagccccaaccagtgcacctcccagcagcctctgcagcagcaaacccagtccctggtgcaccaattgaccctcaggcacagctagaagctgacaagcgggctgtctacagacatccgcttttcccacttttgacactactgtttgagaagtgcgaacaggccacccagggctctgagtgtataacatctgccagttttgatgtggatattgagaactttgttcaccaacaggaacaagaacacaaaccatttttcagtgaggaccctgaactcgacaacctaatggtaaaggctatccaggttctacgtatccacctactagagctggagaaggtcaacgagttgtgtaaggacttttgcaaccgatatatcacatgcctaaaaaccaaaatgcacagtgataatttgctcaggaatgatttaggtggaccatattccccaaaccagccctccaacagcctacatacgcaggacatgttacagaactctccaaactctatgactggtctatccaataacccacaagggattgttgtccctgcttcagcattgcagcaaggaaatatctctatgacaacagtcaactcctctcaagttgtatcaggtggggctctttatcagccagttgccatggtaacttcccagggtcaggtagtaacccaagctatcccacagggagccatacagatccagaatgcacaggttaacctggaactgacctccctgcttgacagtgaagataaaaagtctaagaacaagcgtggagtcctgccaaagcatgctactaacattatgcgctcttggcttttccaacatctgatgcacccttacccaacagaggatgagaagcggcaaatagcagcacagacaaacctgacactgttgcaagtcaacaactggtttatcaatgcaagacggcgcattctccagccaatgttagatgccagcaatcctgaccctgcaccaaaagctaagaagattaagtcccagcatcggccaactcaaagattctggcccaactctattgcagcaggtgttctgcaacaacaaggagggttacctggcactaatcctgatggttctgtcaatatggaaaacctgcagtcactctcatctgactccctcacgatgcagcaggccatgatggcagctcatgatgactcactggatggtacagaggaggaagaggatgaagaagaaatggaggaggatgaactggaagatgacagtgaggaacttcagacgacaaatgttagtgaccttggtttggatcacagtgactccctggagtaaaactttgatcaggtggagaaaaagggtggttaaaggcacactttgcattgatctaaagctcaaatagccttggaatatctttaaataacccactcctaccttctaatcaatcatggaacagactctccagttatctgttgctcaaatgtaacagcctgcacctctttttaagtggaagacaagacatctgccagcacacaaggtggaatagaacctgccaaactaggacaaagtctaatccactgtaagaagaactgttgaattctttcttttccctaacccagaggatttgaaaagctggaactcccttgtaaaatgcgatccttgtagaccattctggaaacagaacaaaaaaaatgcaaatatccattactttcatagttgcctgcttgtatcattgtttcatggcagggactttacaatattatggacaaagcaattgtgcagtctttttatttaaacaaaggacacatgtttacagagccacatattgtggttactttgttttgtttgtcttttaaagaacttaacgtgtttttaggcaaagctttttctgtattattactgaaagctatttgaatgttaaagtttatatactgtatgtgtgtgcgtgtgtatatatctatacacacatacacacacacatacatgcacagaatataaatacacagctggagagtgctgtatggatattctgatatttgtacaacacgacgctccatccctatatactgtacatgaaacacacacacacactactttcaggaggctggtactaaaatcattgaccattttgagaactaagtttgtgtgtaaaattacaaaactgcatccctcgacctttcaaatgatgtaatatcagactcatctattttggcaagtatacggttttatgaaatttccatataaacagagtatgaaaatgaagaaagtacttgaatgtgtgcatgtgttatcacgaagatatctttgttctggctcctaatcattattctgcattaacagtgcacatacttttagcttctctatatctttgataagttgtggttataaattttaatgttttagggttaagtggggttgtttgtctatgcaatgtttactggtctttaactgaccccagagtcaaaatgcacacatcaaactccctctcaaacatgaaaccacttaaggcacaaaatgtaagcaatgatggtgctggacaccaaacttaaaaaaggcacagcattaatctgggtgtagattaaagaataactatagaaaatgcccagtcttgctgcaaatcttgaggtttatgtagcagggagaatatattggttatcccaactggcttccacatgttttgtgtaacagaatcctgcttctgtgacttttctgtaatagggatatacattctgtgaatgacactgaatgtgtgtctcagctttgttacagggttcttattgagaaattgaatgaaataaaccacagtggttagattctaaaaaaaaaaaaaaa

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