LOCUS       NM_001001227            4021 bp    mRNA    linear   VRT 14-JUL-2023
DEFINITION  Xenopus tropicalis SERPINE1 mRNA binding protein 1 (serbp1),
            transcript variant 1, mRNA.
ACCESSION   NM_001001227
VERSION     NM_001001227.3
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 4021)
  AUTHORS   Fierro AC, Thuret R, Coen L, Perron M, Demeneix BA, Wegnez M,
            Gyapay G, Weissenbach J, Wincker P, Mazabraud A and Pollet N.
  TITLE     Exploring nervous system transcriptomes during embryogenesis and
            metamorphosis in Xenopus tropicalis using EST analysis
  JOURNAL   BMC Genomics 8, 118 (2007)
   PUBMED   17506875
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4021)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF786145.1, BC067912.1, AAMC04000004.1 and CX497317.2.
            
            On Aug 3, 2013 this sequence version replaced NM_001001227.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067912.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                CF786145.1         20-69
            51-1449             BC067912.1         1-1399
            1450-3259           AAMC04000004.1     83583101-83584910
            3260-4021           CX497317.2         9-770               c
FEATURES             Location/Qualifiers
     source          1..4021
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="4"
                     /map="4"
     gene            1..4021
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /note="SERPINE1 mRNA binding protein 1"
                     /db_xref="GeneID:407908"
                     /db_xref="Xenbase:XB-GENE-494265"
     exon            1..393
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    117..119
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /note="upstream in-frame stop codon"
     CDS             129..1349
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /note="isoform 1 is encoded by transcript variant 1; PAI-1
                     mRNA binding protein"
                     /codon_start=1
                     /product="SERPINE1 mRNA-binding protein 1 isoform 1"
                     /protein_id="NP_001001227.1"
                     /db_xref="GeneID:407908"
                     /db_xref="Xenbase:XB-GENE-494265"
                     /translation="

MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEGAGGPGQGTGKTAAQAAKQPKKESQKDRKNPLSEKEEKSQAPVPIKKEAIRRVGRRPDQQQQPPQQPPTQQQQQQQQQQQQQQQPPQSSQGEGKPVDRRQSDRRPPRERRFEKPTEEKGEAGEFSVDRPIVDRPIRGRGGPGGRGGRGGRGRGLGRGDGFDSRGKREFDRHSGSDRASSHFSGPKHEDKRGGSGSHNWGTVKDELSELDQSAVTEETPETEEHPAVDSENKENEAEEVKEEGPKEMTLDEWKAMQDKERSKVEFNIRKPNEGADGQWKKGFVLHKAKSDEVHAESDALDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRARGGRPSRGGRTDKSNASAPDVDDPEAFPALA"

     misc_feature    141..>422
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /note="Intracellular hyaluronan-binding protein 4
                     N-terminal; Region: IHABP4_N; pfam16174"
                     /db_xref="CDD:465041"
     misc_feature    738..1061
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /note="Hyaluronan / mRNA binding family; Region:
                     HABP4_PAI-RBP1; pfam04774"
                     /db_xref="CDD:461421"
     exon            394..631
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            632..778
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            779..865
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            866..940
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1118
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1292
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..4007
                     /gene="serbp1"
                     /gene_synonym="cgi-55; chd3ip; habp4l; pai-rbp1; pairbp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cccggatgtctatcgcgccggaagagaagacagcctctttcccagccatcttttggcttactagcaagcgagctctaggctccaggcctcgtagaatcggaggaacatccacctcttaaggggccatcatgcccggtcacttgcaggaaggcttcggctgcgtcgtaaccaatcggttcgaccagctatttgacgatgaatctgaccccttcgaggtgttgaaggcggccgagaacaagaagaaggagggcgcagggggaccgggtcaagggaccggcaaaacggcagctcaggccgccaaacagcccaagaaggagtcccagaaagaccggaagaaccctctgtccgaaaaggaggagaagagccaggcgcctgtaccaatcaagaaggaagctatcaggcgggttggtcggagacctgatcagcagcagcagccgccgcagcagccaccaacacaacagcagcagcaacaacaacaacaacaacagcagcagcagcaaccacctcagtcatcacagggtgaaggaaagccagttgacaggaggcagtccgataggcggccaccccgtgaacgccgttttgaaaaaccaactgaagaaaagggagaagcaggggaattttctgttgaccgacccatcgtggataggcccatccgtggtcgcggtggccctggtggaaggggtggccgtggcggtcgtggacgtggtttgggcaggggcgatggctttgactctcgtggaaaacgtgaatttgacaggcatagtggcagtgacagagcttcttcacatttcagtggcccaaagcatgaggataaacggggaggaagtggatcacacaactggggcactgttaaggatgaattaagtgaactggaccagtctgcagtcactgaggaaactcctgaaactgaagaacatcctgctgttgattctgaaaacaaggaaaatgaggctgaagaagtgaaggaagaaggtcctaaggaaatgactctggatgaatggaaagcaatgcaagacaaagaacgttcaaaagttgaattcaacatccgtaaaccaaatgaaggtgctgatggccaatggaagaaaggctttgtcctgcataaagcaaagagtgatgaggttcatgctgagtcagatgccctggatcatcatttccgtaagcctgcaaatgacataacttcccaacttgaaattaactttggagatcttggacgccctggtcgtggaggcaggggaggaagaggcggccgtgcccgcggcggtaggcctagtcgtggaggaagaactgacaagtcaaatgcttctgctcctgatgtagatgaccccgaagcttttccagctttggcgtaagcttggatgacttgtccaactttggtgcccctgagggaccccttctacgaggcttgcatgcttaaggatcctaaactactacaaattaaaaaaaaaaaaaggaaaaaccccaagactgtcaatcataccattcacacctatggactgaattttatctgttttgaaaaatggacttctctcgctactcagaagcaacaatatggtagtcaagtttttgtatttagagatgttatggtagcagggatgttttcataatttttcagagaatatgcattcttcatggatacttttttgtattgctgcttgaaaatatgcgtttccaaacttgaaatataggtgtgaaaagtgtgtaccagttaaagctttcacttatttgttctttgttttttttcccccaactttaaatcttttttttaacatgctagaaattacccatgtattggcaacttgaactggtcattttcacatctgaccttgccctttgtctagctaaagtcccaatttctatatatctattttcaacttgcaaaggtcattttactttttttttctagattgtgtaagaatacacaaaatttagacattttaaagtacatgaatgtgcttgtcaattttgatcctgtgggtaaatggtgttaatggactgcaactgtagagaattggtaatgtaacgtatcccagtgtgtatgcttatttagcataggatttaattaacatcgccctgagagttatggtaatttccataaactctctaatggaatatgaattttcattttgaattggacatactgagtagcacaaacatgtatccagtgtatgatagcaaaaccaataggaaagtcaaacctgaaaatgccttcatgcaacaaacatcagaagtcaaacaagttactgtgttgcttgttccatttgctgcaacccgtgtgtgaggagaattgctttataaaagagcagcattactgaggtgtttgtcacactggtcccttgcattgtgaagagctttttccatttgcctgggaagtagaacaaacactttgctctaaatagttcttcatagttttcagcttctgggtttggattgctggttgacagatgaatgtttgctcttcagtgagagaatacagctcctactctcatagaatttttagcttatttaattttttttcttcctaaggcctaaacattaccacttcaaaacaaaaggacatgataggctacattaaaaagaaaataaaaataacaaaaaaaaaagttgtctacagtgtttgttaggataaaatactcatttaatttaatgttctttttacagtttttagcaggctataaaatttgaagcttcgtacctatgtaggttaaatgaacacaaatattattgccctatttttataaaagttgtacaggacaggcaacaaagtatttgaatcttttgagtaccaaaatggcagctcattgttcagtagcccgagtgcttatactgtggtactctacagggtgtaggcggctttctggcgctggctgggtcagtggtatttttattcaacagcctggccattttgagattattttctagagagataatttactatgagactgcaaaccagtggagtttttaaagataacacttcaatgcattaacctatcaatttaaataagccttcacaaaatggaaacatgtttaagcagctgagattaagttatgtacagatcccttaagttatctaagagcctcttacacatgcagagtaacatgctagtgtggccctgaaacatccttgctataggcttctttacttttgtacaacagtcttgtactgtccattcaagctaatctattcatttatgaaccttggcttgttcctttgcctgaggaatatcatcattttcagttaaagtgaacttgtatcaaatctgagaattggcactttgtcgaaccaggtctcctggctataaataaaggcactgcagcttcatttaagaactgaatgaacctttgagcatctgttgctagctggtaaatgacaatctgggatttccagtcactagctgaagaattaatgtgcctttccccttcattacccatcatagttgtacatttatctgaagcccatttctgtgtgaactgaaactgtgaacaaatctgtctggtggatgcttattgaattaaaggttaattttcatgctctagcctaatgaagggtaatatggcagctttgttttgtctagtgttttctttttcaaagagttggtatgtgtccctgttgaagacgagacttggttccctccccacagtaactctggtgactacaatctagaatgtgttctagataaatgcattttgtggcaatttttgcatagcaatgaaagtttgcctttatcaataccaccaattactcctggaagtgcttaaattaagtacaggtaggctttcaaagcagggattgtatatgacttttgatgtatacaactgttaatgctaaaataagactactgtgtattttagtttcacattctcaatgtcaatctcattcccaatgaaatttagaacacccatgacattaataaattctggtcagaggcctaaagctgaaataatatttgtaccagttttatgttaatcttgtctgactggtttagaaataaaatttgccaacaggacaaaaaaaaaaaaaaaa

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