LOCUS       XM_063261771            9863 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus dicer 1 ribonuclease III (Dicer1),
            transcript variant X2, mRNA.
ACCESSION   XM_063261771
VERSION     XM_063261771.1
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086024) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9863
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..9863
                     /gene="Dicer1"
                     /note="dicer 1 ribonuclease III; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 9 ESTs, 166 long SRA reads, 14 Proteins"
                     /db_xref="GeneID:299284"
                     /db_xref="RGD:1309381"
     CDS             234..5990
                     /gene="Dicer1"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform X1"
                     /protein_id="XP_063117841.1"
                     /db_xref="GeneID:299284"
                     /db_xref="RGD:1309381"
                     /translation="

MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLSPHAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWSQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCDSCPSCPRILGLTASILNGKCDPDELEEKIQKLEKILKSGAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALDFINDCNVSVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTLLRKIHALCEEYFSPASLDLKYVTPKVMKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDGAEADVHAVVDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMGCVRLAERVVALICCEKLHKIGELDEHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELVTRLHQYIFSHILRLEKPALEFQPAGAESAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYSKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGWKKSIDSKSFISTCNSSLAESDNYCKHSTTVVPENAAHQGATRPSLENHDQMSVNCKRLPAESPAKLQSEVSVDLTAINGLSYNKSLANGSYDLVNRDFCQGNQLTYFKQEIPVQPTTSYPIQNLYNYENQPTPSNECPLLSNKYLDGNANTSTSDGSPAGSPRPAMMTAVEALEGRTDSEQSPSVGHSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKQGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNSEKWEKDEMTKDCLLANGKLGEDCEEEEEEELAWRAPKEEAEYEDDLLEYDQEHIQFIDSMLMGSGAFVKKIPLSPFSTSDSAYEWKMPKKASLGSVPFSSDLEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSRDKASYPAQENSSSQQKSPSGSCAAAVSPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFENFEKKINYIFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPLVPNS"

     misc_feature    357..950
                     /gene="Dicer1"
                     /note="DEXH-box helicase domain of endoribonuclease Dicer;
                     Region: DEXHc_dicer; cd18034"
                     /db_xref="CDD:350792"
     misc_feature    order(357..368,375..377,426..449,570..572,759..761,
                     852..854)
                     /gene="Dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350792"
     misc_feature    order(534..539,606..611,684..686,690..695,702..704,
                     777..785)
                     /gene="Dicer1"
                     /note="nucleic acid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:350792"
     misc_feature    1044..1328
                     /gene="Dicer1"
                     /note="Partner-binding domain of the endoribonuclease
                     Dicer; Region: Dicer_PBD; cd15903"
                     /db_xref="CDD:277191"
     misc_feature    order(1059..1064,1071..1073,1077..1082,1257..1262,
                     1269..1274,1281..1283,1290..1295,1302..1304)
                     /gene="Dicer1"
                     /note="Trbp binding interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:277191"
     misc_feature    1347..1925
                     /gene="Dicer1"
                     /note="C-terminal helicase domain of the endoribonuclease
                     Dicer; Region: SF2_C_dicer; cd18802"
                     /db_xref="CDD:350189"
     misc_feature    order(1578..1586,1794..1796,1851..1853,1857..1859)
                     /gene="Dicer1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350189"
     misc_feature    order(1806..1808,1812..1814,1887..1889,1893..1895)
                     /gene="Dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350189"
     misc_feature    2121..2387
                     /gene="Dicer1"
                     /note="Dicer dimerization domain; Region: Dicer_dimer;
                     pfam03368"
                     /db_xref="CDD:460900"
     misc_feature    2889..3257
                     /gene="Dicer1"
                     /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse
                     involved in cleaving dsRNA in the RNA interference
                     pathway. It generates dsRNAs which are approximately 20 bp
                     long (siRNAs), which in turn target hydrolysis of
                     homologous RNAs. PAZ domains are named...; Region:
                     PAZ_dicer_like; cd02843"
                     /db_xref="CDD:239209"
     misc_feature    order(3078..3080,3117..3119,3135..3137,3147..3149,
                     3201..3203,3225..3227,3231..3233)
                     /gene="Dicer1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239209"
     misc_feature    4119..>4394
                     /gene="Dicer1"
                     /note="Ribonuclease III family; Region: RIBOc; smart00535"
                     /db_xref="CDD:197778"
     misc_feature    order(4170..4175,4182..4187,4194..4196,4203..4208,
                     4215..4220,4224..4232,4260..4262)
                     /gene="Dicer1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238333"
     misc_feature    5265..5759
                     /gene="Dicer1"
                     /note="Ribonuclease III C terminal domain. This group
                     consists of eukaryotic, bacterial and archeal ribonuclease
                     III (RNAse III) proteins. RNAse III is a double stranded
                     RNA-specific endonuclease. Prokaryotic RNAse III is
                     important in post-transcriptional...; Region: RIBOc;
                     cd00593"
                     /db_xref="CDD:238333"
     misc_feature    order(5325..5330,5337..5342,5349..5351,5358..5363,
                     5370..5375,5379..5387,5415..5417,5679..5681,5712..5714)
                     /gene="Dicer1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238333"
     misc_feature    order(5325..5327,5334..5336,5346..5348,5649..5651,
                     5658..5660)
                     /gene="Dicer1"
                     /note="active site"
                     /db_xref="CDD:238333"
     misc_feature    order(5334..5336,5649..5651,5658..5660)
                     /gene="Dicer1"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238333"
     misc_feature    5772..5960
                     /gene="Dicer1"
                     /note="double-stranded RNA binding motif of
                     endoribonuclease Dicer and similar proteins; Region:
                     DSRM_DICER; cd10843"
                     /db_xref="CDD:380680"
     misc_feature    order(5772..5777,5781..5786,5793..5798,5805..5810,
                     5820..5822,5835..5843,5847..5849,5853..5855,5904..5915,
                     5922..5924)
                     /gene="Dicer1"
                     /note="putative RNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:380680"
     polyA_site      9863
                     /gene="Dicer1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

agctgaagcttgggcatgctgtgattttccaataagctatcacaatgtcagaatgcagttcagacagcagcaacacagcgctcgcagacattaaaacggaaactggagcgacttctcttccagtgtcctagagtagtagcagagaacagcacaaagcagaggaaggtgacaattccaaatgcaggattgtaagctgtgctagaacaaaatgcaatgaaagaaacactggatgaatgaaaagccctgctttgcagcccctcagcatggcaggcctgcagctcatgacccctgcttcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataacatttatacgccaagaaaataccaggttgagctgctggaagcagctctggaccacaacaccattgtgtgcttgaacactggctcagggaagacgttcatcgccgtcctgctcaccaaagagctggcccaccagatcaggggcgacctcagtccgcatgcaaaaaggactgtgttcctcgtcaactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcactcagatctcaaggttggggagtactcaaacctcgaagtgaatgcatcttggacaaaagagagatggagccaagagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaaaatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgcaattctagaccacccctatcgtgaaattatgaagctctgtgacagttgtccatcatgccctcgaattttgggactaactgcttccattttaaatgggaaatgtgacccagacgaattggaagaaaagattcagaaactggaaaagattctcaagagtggcgctgagaccgcaactgacctggtggtcctggacagatacacttctcagccttgtgagattgtggtggattgcggaccatttactgacagaagtgggctttatgaaagactgctgatggagttagaagaagcacttgactttatcaatgactgtaatgtatctgtacattcaaaggaaagagattctactttgatttccaaacaaatcctctcagactgccgtgcagtgctggtcgtcctgggaccctggtgtgcagataaagtagcggggatgatggtaagagaacttcagaagtacatcaaacatgagcaagaggagctacacaggaagttcttattgtttacagacactctgctaaggaaaatacatgcactgtgtgaagagtacttctcccctgcctcacttgacctgaagtatgtaactcccaaagtcatgaaactgctcgagatcctgcgcaaatacaagccctatgagcgacagcagttcgaaagtgttgagtggtacaataacaggaatcaggataattatgtgtcctggagtgattctgaggacgatgacgatgatgaagaaattgaagaaaaagaaaagccagagacaaattttccttctccatttaccaatattttatgtggaattatttttgtggaaagaagatacacagcagttgtcctaaacagattgataaaggaagctggcaaacaagatccagagctggcttatatcagcagcaactttataactgggcatggcattggaaagaaccagcctcgcagcaagcagatggaggcggagttcagaaagcaagaggaggtacttaggaaatttcgagcacatgagaccaacctgctcattgcaacaagtgttgtagaagagggtgtggacattcccaagtgcaatttggtggttcgttttgatttgcccacagagtatcgttcttacgttcagtctaaaggacgggcacgagcaccgatctctaattatgtaatgttagcagacacagacaaaataaagagctttgaagaagacctcaagacctacaaagctatagaaaagatcttaagaaacaagtgttcaaagtcagtggatggtgctgaggctgacgtccatgctgttgtagatgatgatgatgttttcccgccatatgtactgaggcctgatgatgggggtcctcgagtcacaatcaacactgccattggacacatcaacagatattgtgctcgattaccaagtgatccgtttacgcatctagctcccaaatgtagaacccgagaattgcctgatggtacattttattcaactctttatcttccgattaactcacctcttcgagcctccattgttggtccaccgatgggctgtgtacggctggctgagagagtggtagctctcatctgctgtgaaaaactgcacaaaattggtgaactggatgaacatttgatgccagttgggaaagagactgttaagtatgaagaagaacttgacttacatgatgaagaggagaccagcgttccagggagaccaggatccacaaaacgaaggcagtgctaccccaaagcaattccagagtgcttgagggagagttaccccaaacccgatcaaccctgttacctgtatgtgataggaatggtcttaaccaccccccttcctgatgagctcaacttcaggcggcggaagctctaccctcctgaggacaccaccagatgctttgggatcctgacagccaaacccatacctcagatccctcactttcctgtgtatactcgctctggagaggtcaccatatccatcgagctgaagaagtctggtttcacactgtctcaacaaatgcttgagctggttacgagactgcaccagtacatattctcacacattctccggctcgagaagcctgccctggagtttcaacccgcgggcgctgagtcagcgtactgtgttctacctcttaacgtcgttaatgactccagcactttggacattgactttaaattcatggaggatattgagaagtctgaagctcgtataggcattcccagcactaagtattcaaaggaaacaccgtttgtttttaagttagaagattaccaagatgcagttatcattccaagataccgcaattttgatcagcctcatcgattttatgtagctgatgtgtatactgatcttaccccactcagtaaatttccttcccctgaatatgaaacttttgcagaatattataaaacaaagtataaccttgacctgaccaatctcaaccagccactgctggatgttgaccacacatcttccagactgaaccttctaacccctcggcatttgaatcagaaggggaaagcacttcctctaagcagtgctgaaaagaggaaagccaaatgggaaagtctgcagaacaaacagatactggttccggaactctgtgctatacatccaatcccagcatcactgtggagaaaagcagtttgtctccccagcatactgtatcgccttcactgccttctgactgcggaggagctcagagctcagacagccagcgatgctggcgtaggagtcagatcacttccggccgattttagataccctaacttagacttcgggtggaaaaagtctattgatagcaagtctttcatctcaacctgtaactcctcgttggctgagagtgataattactgtaagcacagcacaactgtagtccctgaaaatgctgcacatcaaggtgctactagaccctccttagaaaaccatgaccaaatgtctgtgaactgcaaaaggttgcccgccgagtcacctgctaagctccaaagtgaggtttcagtggatcttacagcaatcaatggtctttcttacaataaaagccttgccaatggcagttatgatttagttaacagagacttttgccaaggaaatcagctgacttacttcaagcaggaaatacctgtacaaccaactacctcatatcccattcagaatttatacaattatgagaaccagcccacgcccagcaatgaatgtcctctactgagtaataagtaccttgatgggaacgctaacacatctacctcagacggaagccccgcagggtccccaaggcctgccatgatgactgctgttgaagcactggagggcaggacagactctgagcagagcccttctgtggggcactcctcaaggactctcggccccaacccaggactgattcttcaggctttgacactgtcgaacgctagcgatgggtttaacctagagcggcttgagatgcttggcgactccttcttaaagcacgctatcaccacgtatctgttttgcacataccctgatgctcatgagggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaacctgtaccgccttggcaagaagcagggactgcccagccgcatggtggtgtcgatatttgatcctcctgtgaattggcttcctcctggttatgtggtaaaccaagacaaaagtaactcagagaaatgggaaaaggatgaaatgacaaaagactgcttgctggctaatggcaaactgggtgaggactgtgaggaggaggaggaggaggagctggcgtggagggctcccaaggaggaggctgagtatgaagacgacctcctggagtatgaccaggagcacattcagtttatagacagcatgctaatgggctcaggggcctttgtgaagaaaatccctctttcccccttttccacctctgattctgcatatgaatggaaaatgcccaaaaaggcctccctgggcagtgtgccgttttcctcagaccttgaggattttgattacagctcttgggatgcaatgtgctatctggatcctagcaaagccgttgaagaggatgactttgtggtaggtttctggaatccatcagaagaaaactgtggcgtggacacagggaagcagtccatttcttacgacttgcacactgagcagtgcatcgcggacaagagcatagcggactgcgtggaggccctgctgggctgttacttaaccagctgtggtgagagggctgctcagctcttcctctgctcgctggggctgaaggtgctcccagtcatcaaaaggaccagccgggacaaggcctcgtaccctgctcaggagaactcaagcagccaacagaagagcccttcagggagctgtgctgctgcagtcagtccccgctcctctgcagggaaagacttggagtatggctgcttgaagatcccgccaaggtgtatgtttgaccatccagatgcagagaaaaccctgaaccacctcatatctgggtttgaaaattttgaaaagaaaatcaactacatattcaagaataaggcttaccttctgcaggcttttacacatgcctcctaccactacaacactattactgattgttaccagcgcttagaattcctgggagatgcgattttggactacctcataaccaagcacctttatgaagacccacggcagcattctccaggggtcctgactgacctgcgctctgccctggtcaataacaccatctttgcgtcgctggctgtgaagtatgactaccacaagtactttaaagccgtctctcctgagctcttccacgtcattgatgacttcgtgcagtttcagctggagaagaacgagatgcaaggaatggactctgagcttaggagatccgaggaggatgaggagaaagaagaggatattgaagtccccaaggccatgggagacatttttgagtctcttgctggtgccatttatatggacagtgggatgtccctggaggtggtctggcaggtgtactatccgatgatgcggcctctaatagaaaagttttctgcaaatgtgcctcgttctccggtaagagaattgcttgagatggaaccagaaactgccaagtttagcccagcggagagaacttacgatgggaaggtcagagtcaccgtggaagtggtgggaaaggggaagtttaaaggtgtcggccggagctacaggatcgcaaagtctgctgcagcacgaagagccctccgcagcctcaaagctaaccagcctctggttcctaacagctgaagcttccagactcacaggcggcaaggcagtgaccagaaccatagcagcacaccacaaaggatgactcaagccgacacagagcagaaagattgacggcagaacttaaagtttgataatgagatagataacagaataaaacctttaatatgtgtataaactctttggaactaattgtagctttagtttttgcgcagacacaatcttgtcttctttatccaccctgctttgtttagtcacaggagcgctttgatgctggtgtttattggcgagtttttaaatcactttgacaggtttctgggtttttatttgtttgtttttgttttcacatttcatttctgttgacttgacttggcttggtgttagagatcatggagcttaaccctctgacagtccctagagctcgggggtcctgaccctgcggttcctccacaccagtgcctgtttgctgcagttgtcaagcccagcaaagcagaacagtttgcaaaggaagctctggtgttgtggagggcagtggaggaaggggcggggcagccccctgtcgctgtggcacatagtagtaagggacagacttggagtcagtgttggccatcgatgagtcgaggccaggttttcagaggtcacgtagtgctgcagagggctcttgccttaaaagtacgggcctgatagtttgctttcttatcttgccttcccgggttatgcattggatgagatgggtggcagctcaccagagcacctgcaccagaattactgcagtaggatttctgttgcgtgtcctgaaaacattcgaaaacccggcgtgagtagatggagttttaaagcaccattatagacaggatatgtggctagatgcccagttttcctcagaactttctgccaggggtcccagtggtggaagtgcttgcccagtcgaccattgttcattgacaaaatgagcctgagatgcagtccgcctagatagacatgccgcaggtttgtactggagcacgtcctggcagtgttgccagagtcacccatgctgggccgtcagtctcatggggtcagcattgaggcagactgccaggactgactcgtctggggtggaagtcgtgagtttagataaactaggtccttagttcatctcagaatcagagaaactaaagctgtttaggcatttgctgaagcgcctggaccgggcttgtgggccctcttcacttacacacctcagtcccctccctttgcgtgcattttcccgttggtgctatgtttatgtatcatgcttgaagtttaattttttgcactgtgactataatacctcttaatttacattttaaaatgctatatgggttgctcatgccctcccaccgacatacaggagagttttgctgcatttagccctattacgcttgaagtttcagcacgctgagccagggtggctcgtgcttcccacacgtcttctgaggctgatgcttcatgcaatgctgcacttaggttccagtcacctttggcttcactgcaccatccgctcgagagagacgccgtgtgcgctgagcactcgggctgtcaggtaccccacgtgaagggggggagagtgagcttctccaaggattacgtaattgcccatctgaaaatcgggatctgaattagtgtttggtgaaatcaatttggctgactcatcttaaatatttaattctaacttgaaattgtagttgtctatttgatttagaacatccctctcccccatgcacacacacacacacacacacacacacacacacacacacacacacacccctacatacaaacacaccccccccacacacacacacacaaaccttaatgcaagacatcatagcatgtgcaaaccaggtgatcttttgaatgttgtagctataatttgtacagtgagatagtaaggtagggtgggattgtgggaggtggaatttgttgtcctattaccgtctcttggtaatttataaactacctgattctctgcattgtgatttgtgcatttatgtcctggggtgctctggcatcctggcaccaaaatcagactgttttacagttccattcctggtggaagaaaatgcctcaatatattttgtaaccataaggagagtatttttttgttaatattaaaaagatcagaattggatatgcttagatcatccattctcagggctcaaattttatgccactattcagaatgttgtatcagtagcaaacttgggctgtttttccttttatccccccgtacccgcctctttttggttgttgtttgataaaagtacctgaaaattaatttgacccacagtttgaatcatactgtgatttacccagagaccaagttggggaatcagaagtacgatgacgagttagacacacgcgaagatcaggaatgcatttgtgttggggagttgtccccaggctctcactggttgaaagactgcattttagagaaaagttgttctgttccctcccgtgatgacttcgtgtgcctcccctgccagtgtagcaggaggaggagaagccagccagcggctgtgaggacgaggtgggccgctgcacagatgctgtggctgtgcgtgagctcctggggtgctgcagtactgggacaccccctgtggccccttggcaatcccagccgtacagagggagggagggaggccctgtcttctgttgggttgtgtccatgaagcatgggctggccagtgttccagaggggaggcctgtggttctgacttgacaacatacggggatgcctacagcttgtcacacacttgcacactttagctattattattactttgtctgtggcattttcttctgtctgtaaagtgaaagcacggcagaaatgtgttgactgaacacttaattatgctttttaaatgttttggttacgtttcttttttcatttatattatatgaaatgattaaatttagaataacctctaacactcctataattatcatttaaaatactgatgtttttattgtctcgacagtagtccgtcctcagaacagtgcagacacactgtgtgattagcagggacttgaggctgttttggttctgccgttcagttcctgtgtacagtcgctcaccagcagccaccagacagtggctgcgagcgtggagaacagtcaaaaatccacaacctcccggtttgcttgtagggcctattgatttaaaactactccttgctcggtgaaggcacctagtcctcctgcacaaacgtaacgctggcaaacggaggccttgcacctttatttcacagcccctgagctgagccgccagccgcatccttagccaactgtgtctgcagcgggctctgtgtctcctctgtgcttaacaacgtccgagaacccatagcttcccacctgctgatcgcttctctggaatttaattatttttcaataaattctgtagtttatactgtatatgagacattttaaagatagttgaaatgactgtaaaggtggtgtgtctgccatggagaccgtgtgttgtccactggcagggaaaatgatcacctctaacttgcagatagtactttattcattattttcttgtctgtttttctttgctaaacaaccacagacagtttcagtgtcatagatggccccagagtttgcctcggctgctggttccatagcggaagaacgcatctgccttctctgctgtaaataaaggggagtcactagcgaagtcaggctgagcgttccgctgacaatgaactacgtccgtcacatgctgcagccttttaaagaaacgtatttgtgcatacagcggtcactgtagagctgcaacagcacctccggaccacagtcacctttagctttccgttccgtttgtttttctttttaataattgtagccaataaagttattgtctgttca

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