LOCUS       XM_006256375            8641 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus GRIP and coiled-coil domain containing
            2 (Gcc2), transcript variant X1, mRNA.
ACCESSION   XM_006256375
VERSION     XM_006256375.5
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086038) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Feb 22, 2024 this sequence version replaced XM_006256375.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8641
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..8641
                     /gene="Gcc2"
                     /note="GRIP and coiled-coil domain containing 2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 mRNAs, 7 ESTs, 885 long SRA reads, 3 Proteins"
                     /db_xref="GeneID:309798"
                     /db_xref="RGD:1305732"
     CDS             2172..7217
                     /gene="Gcc2"
                     /codon_start=1
                     /product="GRIP and coiled-coil domain-containing protein 2
                     isoform X1"
                     /protein_id="XP_006256437.1"
                     /db_xref="GeneID:309798"
                     /db_xref="RGD:1305732"
                     /translation="

MEVTDSAQDAVTAAPSGTPKSKLETLPREDLIKFAKKQMMLLQKAKARCTELDKEVEELKSKPVDGGTDDMIKVLTERLDALLLEKAETEQQCLCLKKENIKMKQEVEDSVTKLEETQKEFEQSHRNYVREMESVKNELIAVHSEHSKEKAALQRDLEGAVHRQAELLEQLKSQSDSEDNVKKLQEEIQNITAAFEEQTSCLQKQLEATSDEKQQEIIHLQKVIEDNAQHYQKDINTFQEEIVQLRATHKEEVNELMSQMETLAKEHEAAVNKLKENRVTLCETSETIPENYQCESESLNEDTSDASQENQKCSVALQEDPFAEHTVYDKVRQLEDSLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQSYVVEKLKYEREDLNRQLCCTVEQHNKEIQRLQEHHQKEISELSETFMSGSEKEKLALMFEIQGLKEQCENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQASDVHELQQKLRTAFNEKDALLETINRLQGENEKLLSQELVSELESTMKNLKADNSMYLASLGQKDTLLQELEAKISSLAEEKDDFISKIKTSREEIDDLHQKWEREQKLSVELREAAEQAAQHNSELRQRVSELTGKLDEILREKSQNDQNIMVQMKTMTEDQEALSSKIKSLYEENNRLHSEKVQLSRDLEALQSQQDFAYKEHVAEFEKKLQLMVEERDDLNKLLENEQLQKSFVKTQLYEFLKQMRPSILEDNEEEDVVTVLKAVGESLVTVKEEKHNLVFEYDARVLELERRIKCLQEESVVQCEELRALVRDSEQEKILLRKELDEVTSTKEALQCDILEMKNTNEKTSLENQTLSTRVEELSRSLHSKNEVHNEKDLVIEHENLRLSLEQRESELQDVRAELMLLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEKISKIKLVAVRAKKELDSNRKEAQTLRDELESVQSEKDRLSASMKEFIQGAESYKNLLLEYDKQSEQLDVEKERANNFEHHIEDLTKQLRDSTCQYEKLTSDNEDLLARIETLQANARLLEAQILEVQRAKGVVEKELEAEKLQKEQKIKEHVSTTNELEELQLQFQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSKIEDLEQEMKIQKQKQETLQEEMTSLQSSVQHYEEKNAQIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEMTSEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRTAKAEQAAVTSEFENYKVRVHNVLKQQKNKSVSQAETEGAKQEREHLEMLIDQLKIKLQDSQNSLQISVSEFQTLQSEHDTLLERHNRMLQETVTKEAELREKLCSAQSENTMLKSEHAQTMCQLTSQNEALRNSFRDQVRHLQDEHRKTVETLQHQLSKVETQLFQLKSEPPTKSPASSHQPSKSLRERRTTDLPLLDMHTVTREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDSKLERLTEASLWHTEFTKEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSGWASYLHSWSGLR"

     misc_feature    2400..4667
                     /gene="Gcc2"
                     /note="RecF/RecN/SMC N terminal domain; Region: SMC_N;
                     cl47134"
                     /db_xref="CDD:481474"
     misc_feature    3561..5864
                     /gene="Gcc2"
                     /note="chromosome segregation protein SMC, common
                     bacterial type; Region: SMC_prok_B; TIGR02168"
                     /db_xref="CDD:274008"
     misc_feature    <5403..>6992
                     /gene="Gcc2"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; Region:
                     Smc; COG1196"
                     /db_xref="CDD:440809"
     misc_feature    6804..6998
                     /gene="Gcc2"
                     /note="Rab binding domain; Region: Rab_bind; pfam16704"
                     /db_xref="CDD:435531"
     misc_feature    7002..7130
                     /gene="Gcc2"
                     /note="GRIP domain; Region: GRIP; pfam01465"
                     /db_xref="CDD:460221"
     polyA_site      8641
                     /gene="Gcc2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gtggttttcttagtggttccatctgttacaaagaaaagtttccttgaagaggggtaaagactaaacccatctgatgtacaaggacaagtgttcatattgcagggggttatgctggcttagtaaattaatggttgtacactctcttccaataactacaatttcagtagcaccgatcagttaggttggtttccagtacaaggcatggcttcccttgaggtatacttgccatgctgaactctgactaccaggctgtgctggttattgtggttcataagtggcatacctgggaaggacttctttccctcctctggaagcttacgtggtaacttccggtaccaagaaaactagtcctcagggagcctatattcaagccagttctagctcagggtactgaagctgtttttatatcatggggtaaacactagtactctcttttgaaaatagtttacttttcagctcttttcaagaactaatgctttttaccttgggctattttgctgttcttctttctcccaaaacaaagttgagagaccagtttgatacaaaacaaggcatttcagagggcaattaaaaaatctacaggaaaatcccacctctagagccagcttctcactgaatttaaatagtgcatggaaattgactaacagtaggtatttgacccactgttaaactgaagaaaataactgtttctgaaggatcagagaaaaaagagaaggtatccagttgcttgctgtgctgttattgggaatgaggattgagaggaggtaataattttctccccctcagagtattatcagggagaaaacttcattttgaatggaaaacctctgatgcctttatattttgtaaaaatcatgccatataaattccagaagccatgatcaaaaccaacaaaaatacctggcttttgccatatgtaactttaaacactcttgggctctgcttggggtgagggcccaactgcttgaaggccagggcctgcaattagcgtatgcctatacctggaagtagacaacctgagaaacctgctgaatgaatgccccatcacctatgaaaatacaacatgttgactaatattcccacccgcagccactttttctgtcctctagtttatgtttagaccatgcttaactatagaaaaatatcagggatttttttgaaggcctatgtcagtctaggggtgccctgttatcactctataagacaataacgatgaaaatctgtattataatatcttccctctactctctgcttcttctctagagtcctctggggttttgtttggttggtttggttttccttatcttgccttcatccccttgtgagtacctatgaggaaaaggaaggactctctgacagaacccttgaatccctttaccctgccctctctcattagtgatcacaagggagggtgcttatcagacactagtcactcttaaccttcccacactgtgaccttggtgaattctttcagattaatgccggttttcagtctgatttctcctttttatgcagccatggacaccagtctgtggaatgctgccacccacagttactgtgggtccccatagctcaattaatcttgtctagataaatctctctcatacatgctagaggttgtctcctagatgattataggtcctttcaaattgacaatattaacaacacaagaagcaccttagcccgtaaattaatatttggaaatacagagtcagcatgccaccattttgaaactcctgggaacgtaatggatcccgtgatttattcccaattactattcacaaaggaaactattttgaacaagacagaattaagtcacattaaactatttgtttcacatatgcctactagtctggatagttaaatttgtaaaccacatttttaaaaactaggaaacaaagtgataaaaggaacctgtgctcaagcttgtccctaggcacaggacggtgctgggcgactcagcatgctctggcttggccaggggacctgcgcacagagaacttcctcccagacacccaggaggaagcggaagtgccgctctgcgtagccttggagacgcgggggaggcgtagtcgcctcgttgcaagacctttgacccgcgctccgccgcctcagaggcggagtacctaggacgcctgaaaaggccgaggtggccgcgggtcgctgccacgatggaggtaacggattctgctcaagatgctgtgactgcagcaccctccgggaccccgaaatccaagctagaaacattgcccagagaagatctcatcaagtttgccaagaagcagatgatgctcctacagaaagccaaagcaaggtgtacagaattagacaaagaagttgaagagctcaaatcaaaacctgttgacggaggaactgatgatatgattaaggtgctaactgaacgcttggatgctcttcttctggaaaaagcagagactgaacaacagtgtctgtgtctcaaaaaagaaaatattaaaatgaagcaagaggttgaggattctgtaactaaactggaagagacacaaaaagagtttgaacaatcacatagaaactacgtaagagaaatggaaagtgttaaaaatgaactgatagcagtacactcagagcacagcaaagaaaaggctgccttacaaagagacctggagggagcagtccataggcaagcagagctgttagaacagctcaagtctcagagcgactctgaagataatgttaaaaaactacaggaagagattcagaacattacagcagcatttgaggaacaaacgtcatgtctacaaaagcaattagaagctaccagtgatgaaaaacagcaagagattattcatctccagaaagtcattgaggacaacgctcagcactaccaaaaagatattaatactttccaagaagagattgtgcagctgagagctacacacaaagaagaagttaatgagctgatgtctcaaatggaaacattagctaaagaacatgaggcagcagtaaataagctaaaagagaacagagtgacactgtgtgagacaagtgagaccattccagagaattaccaatgtgaatcagaaagcttaaatgaagacacctcagatgcaagccaggagaatcaaaaatgctctgtggccttacaggaagatccttttgcagaacatacagtgtatgataaagtcagacaattggaagattcattaaaagaactggaatctcaacatagtatcttaaaagatgaagtgacttatatgaataatctcaagttaaaacttgaaatggatgcccagcatataaaggatgagtttttccatgaaagagaagacttggagtttaaaattaatgaactgttgctggccaaagaagaacagagctacgtagtagaaaaattaaaatatgagcgagaagatttaaataggcagctttgctgtactgtggaacaacataacaaagaaatacagcgtcttcaggagcaccatcagaaagaaatctctgaactaagtgagacatttatgtcaggttcagaaaaagaaaagttagcattaatgtttgaaatacagggacttaaggaacagtgtgaaaatctacaacatgaaaagcaagaggtagttctaaattatgagagtttacgagagatgatggaaattttacaaacggaacttggagaatctgctggaaaaataagtcaagagtttgaaacaatgaagcaacagcaagcatctgatgttcatgagcttcagcagaagctaagaactgcttttaacgaaaaagacgctcttcttgaaactataaatcgcctacaaggagaaaatgaaaaattattatcacaagaattggtatcagaactcgaaagtaccatgaagaaccttaaggcagataatagcatgtacttagccagccttggtcaaaaagataccctgttacaagaattagaagcaaagataagttctcttgctgaagaaaaagatgattttataagtaaaatcaaaacttcccgtgaagagatagatgatctccatcagaaatgggaaagggaacagaaactgtctgtagaactcagggaagcagcagagcaagccgcccagcacaacagtgaactgagacaaagagtaagtgaattaacaggaaaactagatgaaatattaagagaaaagagtcaaaatgaccaaaacattatggttcaaatgaaaaccatgacagaagaccaagaagcattgtcatctaaaatcaagtctctttatgaggaaaacaatagactgcattctgaaaaggtccagttgagtagagatttagaagctcttcagtctcaacaagattttgcctataaagagcatgttgctgaattcgaaaagaaactccagttaatggttgaagaacgagatgatttaaataaactgcttgaaaatgagcaacttcagaagtcatttgtcaaaactcagttgtacgagtttcttaagcaaatgaggccaagcattttagaagataatgaagaggaagatgttgtcacagttctaaaagctgtgggtgaatccttagtgacagtaaaggaagaaaagcataacttagtctttgaatatgatgcgagagtattagaattagaaaggaggattaagtgccttcaagaggagagtgtagttcagtgtgaagaactaagggctttagtaagagactctgaacaagagaaaattctcctaagaaaagaattagatgaagtcacatcaacaaaagaggccctgcagtgtgatattctagaaatgaagaatactaatgaaaaaacaagccttgaaaatcagactctttcaactcgggttgaagaattatcgcggtcattacacagcaaaaatgaagtccataatgaaaaggatcttgtcatagaacatgaaaacctgaggctatcgcttgagcagagggagtctgagctacaagatgtgagagcagaattgatgctgctgaaggattccttagagaaatcgccttctgtaaaaaatgatcaactttcattggtaaaagagctggaagaaaaaatagaaagtctggaaaaagaatccaaagacaaggatgagaaaatcagtaagataaaactagtcgctgtgagagcaaagaaagaactagattctaacaggaaagaggcccagacactacgggacgaactcgagtccgtacagtcagaaaaggaccgcttatctgcttctatgaaggagtttatccaaggagcagaaagctataagaatcttctgttagaatatgacaagcagtcagaacagctggatgtggaaaaagaacgtgctaataattttgaacatcacatagaagaccttaccaaacaattaagagattcgacttgccagtatgaaaaactaacttccgacaatgaggatctcctggctcgaattgagaccctgcaggctaatgccaggttattagaagcacagatcttagaggtccagagagccaaaggagtagtagaaaaagaactggaagctgaaaaacttcagaaagagcagaaaattaaggaacatgtcagtactacaaatgagcttgaagaacttcaactccaatttcaaaaggaaaagaagcagcttcagaaaacgatgcaagaattagaactggttaaaaaggatgcccaacagaccacgttgatgaatatggaaatagcagattacgaacgtttgatgaaagaattaaatcaaaagttaacaaataaaaacagtaagatagaagatttggagcaagaaatgaaaattcagaaacagaaacaagaaaccctacaagaagaaatgacttccctgcagtcttcagtacagcactacgaagaaaagaacgcccaaatcaagcagctgcttgtgaaaaccaaaaaggaactggcagatgcaaagcaagcagaaactgatcacttactactccaggcgtctttaaagggcgagctggaagcaagccagcagcaagtagaagtctataaaattcagctagctgagatgacatctgagaaacacaaaatccatgagcacctgaagacttctgcggaacagcaccagcgcacactaagtgcataccagcagagggtggtggccctgcaggaagagagccgcactgccaaggcagagcaagctgctgtcacctctgaatttgagaactacaaagtccgggttcataacgttctaaaacaacagaaaaataaatctgtgtctcaggctgaaactgagggagctaaacaagaaagggaacacctggaaatgctgattgaccaactgaaaatcaagttacaggacagccaaaacagcttacaaatcagtgtgtcagagttccagacactgcagtctgagcatgacactctgctagagaggcacaaccggatgctgcaggaaactgtgaccaaagaggcggaacttcgggaaaagttatgttcagctcaatctgagaacaccatgttgaagtctgaacacgcccagacaatgtgtcagctgacatcccagaatgaggccctccgtaacagcttccgagaccaagttcgacacttgcaggatgagcacagaaagacagtggagaccttgcagcaccagctctccaaggtggaaactcagctcttccagctcaagagtgagccacccacaaaaagccctgcttcttcccatcaaccttcaaaaagcctccgagaaagacggaccacagacctcccccttctggacatgcacactgtgacccgagaggagggggaagggatggagacaactgacagtgagtctgtgtcttcggccggcacacacattcagtccttggagcagctccttagctctcctgacagcaagcttgaacgtcttacagaggcctccttatggcatacagaatttaccaaagaagaattggctgagaagctcagttccaccacgaagagtgcagatcacttaaatggcctgcttcgggagacagaggctaccaacgccatccttatggagcaaattaagcttctcaaaagtgaaataagaagactggaaagaaaccaagagcgggagaagtctgtggctaacctggagtacttgaagaatgtcctactgcggttcattttcctgaagccgggtagtgaaagagagaggcttcttcctgtgatagacacgatgctgcagctcagccctgaagaaaagggaaagcttgccacagttgctcaaggtgaggaagaaagtgcctctcgttcctctggatgggcatcctaccttcatagctggtctggactgcgataggttgacagaaagaagattctttagtgatgcaacagaactcctttggaaaagctgggtatcatttgatcatgaagtgtgcatctctgttcacatcccctgatgattgtacatatgtatagcccatgtatatagaatctcatcttgtagtaaaaggacatcagcttgaagtagtggtaccaattgttcatggtcctctaactcagcatgtggcctcatggtctctgtgatctccacccacagaggaaacggttcattcctgcactctggaaccccaggagacactcatttctaagtagtattgtgaattttgatattgaactaaattttggtaccaaaccaactggggaatttaatcttttaaaataatgtttcaagattgaggaaatgctttattgataaggttgacatgtttattaaaagattatgaagtaaatatgctatggtttaattatgaggctaacttaaattgcaattcagtcagttactttaaaataaacctccctcccatttgtaattttcaaaattggccctagtcctggtaatgtgacactgacagaataggtgggctccacctcagctgatgtgttctgtggtgtctccaggcttgtttgctgccactcataagccatgagtctcttttgagaattccctacatctcaaaacagtgactgtcttactcagcattaaatctacatgtgaacctggtgcttccagtattgttcaagtattcttatttcctaagcaggaccccagagggctcagaccctctattggtgaacaagcctagctgggggagtgtctctgtccttatgtctctggaaatactatattgactagattaaaattgtgctcttaaatcagatttgggggttatattttaatatgtaatttgttaatgaatagtgctgtctggagtcttaagcttacgtttattctccagttgtcagtctcagcttgaaactgtcctttagtcactatgaatattggtttccaacctggtttgactgaaatttactgctgacatgttgagtttgttctcttaaagctgtttgactctcagtgttcgctctacctgtgttagaacagacctagcaagtgagtgtgctgattcaaacacatctctctcagctgactctttaaggtaaggttttctacctttataaactgtgaatgtgagtatgcccagcggaatcccatgtaatttcagtactatttaaataaactccatgttttctttgggcctaatatgccttttgaagtctgtataaacttgttttcaaatctaatctgttcatatgaatataataaaaataccttttgcatggtaaaaattactttgattacaaaagatatatatatgctttttgtgaccagcaataagaaactgtaatgactgatatttctattaaatgcacttaactata

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