LOCUS       XM_006242061           18363 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus trinucleotide repeat containing
            adaptor 6B (Tnrc6b), transcript variant X5, mRNA.
ACCESSION   XM_006242061
VERSION     XM_006242061.5
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086025) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Feb 22, 2024 this sequence version replaced XM_006242061.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18363
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..18363
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /note="trinucleotide repeat containing adaptor 6B; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 5 ESTs, 1989 long SRA reads, 18 Proteins"
                     /db_xref="GeneID:192178"
                     /db_xref="RGD:621428"
     CDS             1072..6591
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /codon_start=1
                     /product="trinucleotide repeat-containing gene 6B protein
                     isoform X3"
                     /protein_id="XP_006242123.2"
                     /db_xref="GeneID:192178"
                     /db_xref="RGD:621428"
                     /translation="

MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPESTLGGAAASNYANSTWGPGASSNNGASPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSALPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSPNSTSDSNNGLGTWRSTSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTCRKGVLEAEGSSSSAQVSTVGQASREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGADTVSGQSNSGNNGNNGKDREDSWKGASVPKPTGSQSDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPAHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKSTGGWNDYKNNNSSNWGGGRADEKTPSSWNESSCKDQGWGGGRQPNQGWTSGKNGWGEEVDQVKNNNWESSANKPVSGWGEGGQSEIGTWGNGGNTNLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQQQPPPPQPEASGSWGGPPPPPQGNVRPSNSNWSSGPQPATPKDDEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTGKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDAGASATGWGNTPASAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEDDGGVWNTAGSQGSTSSHNSASWGQGGKKQMKCSIKGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVDKKFDVDKRTMNLGDFNDIMRKDRPGFRPPNSKDLGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLSSSPGLRAQVPPQFISPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQQQQQQQQQQQQQQRQPSMKHSPSHPVGPKPHLDNMVPNTLNVGLPDLPTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEATMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPASPWSSTAPRSVRGWGTQDSRIASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATEDEVSRFLAQAQPPTPAATPSAPATGWQSLETSQNQADPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGTSLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI"

     misc_feature    <2047..>2841
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /note="serine-rich protein; Region: ser_rich_anae_1;
                     NF033849"
                     /db_xref="CDD:468206"
     misc_feature    3898..4233
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /note="Argonaute hook; Region: Ago_hook; pfam10427"
                     /db_xref="CDD:463088"
     misc_feature    5188..6024
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /note="TNRC6-PABC binding domain; Region: TNRC6-PABC_bdg;
                     pfam16608"
                     /db_xref="CDD:465195"
     misc_feature    6028..6276
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /note="RNA recognition motif (RRM) found in vertebrate
                     trinucleotide repeat-containing gene 6B protein (TNRC6B);
                     Region: RRM_TNRC6B; cd12712"
                     /db_xref="CDD:410111"
     polyA_site      18363
                     /gene="Tnrc6b"
                     /gene_synonym="Cbl27"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

atttccatagcacacctgccaaaatggagacggggtgggggtggactttctagggtagagagtcaagaggtctctaaggaaaagggacttgggctgcagaaagctaggtaggctttaattgagtgcctagtttcctgagtgccttcctcagcagggaagggattaaagatgactcagagctgcccagcctggaggaatccagtagtgaagccctggcttagtcaagtaaaaaacctaagtaaaaggtttgaggggagaggctacagaagtgttgtactcacacaataggcaccaagttcagactttcctgttctccctttgctgagctgttccgatatgggtgtagcttaacctctctgaatcgacatatgagtgggtatagtaacttcctgtctttttgtgtattttagaggtagctagaaatcagctgtgtcctgtttcgttttaatctaaaaactaaattctctttttgtttaggtaaagctttgtttaaggccccttttaaattaaagagcagtttgccagtctgttcttgcccaaacatctagagaataaccagcaagggagccaagatcagatccaggatctgcaagcatcgttagcaactgagtatatttctataaaccaataaaggtttttctattttgttcatctgttacccttatggtgttgccactttcacatgcagtatctgtaggcgggagtataagtaacagcattgcacaaatgaaagccggtggaaaagggctgctttcgctttaaggcagcttcaactccagctccctccccttttctgattgacaaacctacccgaagtcacgtgacccgcctctatttgaaggtcacaaaaagctgcttcctttagagacagagggggagagagagagcaggagggagagtgagcgagagagttagttcaagccaaaatggccgacagagtctctgctggtttctgaatatttaaaatacaaaatacagatagacaaaaagaattcattttttggaccttttttcatttccatttctaccttgtatgcctcaatttgctggatataagcactgctgcactttatgagagagaaggagcaagaaagggaagaacagttaatggaagacaagaaaaggaagaaagaggataaaaagaaaaaagaagccacccagaaggtcacggaacaaaaaaccaaagtgcccgaagtgacgaaaccaagtttaagccaaccaacggccgccagcccaattggcagctctccatcgccaccagtcaatggtggcaacaatgccaaaagggtggcagtgccgaacggacaaccgccaagcgccgcccgctacatgcctcgggaggtgccaccgcgattccgttgccagcaggaccacaaagtgttactaaaacgtgggcagccccctccaccgtcctgcatgctcctagggggtggggcggggcctcctccctgcacagcacctggagcaaaccccaacaacgcacaagtgacaggagcgctgctgcagagcgagagtgggacggcaccagagtcaacccttggaggtgctgctgcttcaaattatgcaaattccacttggggcccgggagcctcctccaacaacggcgcctcccccaacccaattcacatctgggacaaggtgattgtagacgggtctgacatggaagagtggccttgtattgccagcaaagacactgaatcttcttccgaaaacaccaccgataacaacagtgcctcgaaccctggctctgagaagagcgctctgccaggaagcaccactagtaacaaaggcaaagggagccagtgccagtctgcaagttctgggaatgaatgtaatcttggggtctggaaatctgaccctaaggctaaatctgttcagtctcccaactctacttcagatagcaacaatggactaggaacctggaggagtaccagtggtcaagatagaattggacctggctctggcttcagcaactttaacccaaatagcaacccatctgcctggccagcattggtccaagaaggaacttgtaggaaaggggtgttggaggcagaaggtagcagttccagtgcacaagtcagcacagtaggtcaggcatccagggaacagcagtcaaagatggagaatgcgggtgttaattttgttgtctctggcagagaacaggctcagattcataacactgatggaccaaaaaacggaaacactaactccttgaacttaagttcaccaaaccccatggaaaataagggaatgccctttggaatgggcttggggaacacctccaggagcactgatgccccttcacaaagcactggagatcgaaagactgggagtgttgggtcttggggcgcagctagggggccttctggagctgacacagtctctggacaaagcaattctggaaacaatgggaacaatggaaaagacagagaggactcctggaaaggagcttccgttccaaaaccaactgggtcacaaagtgactcttgggacaacaataacaggtctacgggtgggtcctggaattttggccctcaggactctaatgacaacaaatggggtgaagggaacaaaatgacatctggggtctctcagggagaatggaaacagccgactgggtctgatgagttgaaaattggagaatggagtggtccaaaccaaccaaattctagcactggagcatgggacaatcaaaagggccaccccctcccagaaaaccaaggcaatgcccaggctccctgttggggaagatcttccagctccgcaggaagtgaagttggaggtcaaagcactggaagcaaccacaaagcaggaagtagcgacagtcataattctggtcgtcggtcatacaggcccgcacatcctgattgccaggctgtcttgcagactcttttgagccggactgatttggaccctagggtgctctcaaacactggctggggccaaactcaaattaagcaggacacagtgtgggatattgaagaggtgccaaggcctgaggggaaatctgacaaaggaactgaggggtgggagagcgctgccacacagaccaagaactcagggggctggggagatgcacccagccaaagcaatcaaatgaagtctggatggggggagctctcagcctcaacagagtggaaagaccccaagagtacaggaggctggaatgactacaagaacaacaactcttctaactggggaggaggacgagcggatgaaaagacaccttcctcttggaatgagagttcttgtaaggatcaggggtggggaggtgggcgccagcccaaccaaggatggacttctgggaagaatggttggggcgaggaggttgatcaagtgaaaaataacaattgggaaagttctgccaataagcctgtgtctgggtggggtgaaggagggcagagtgaaattggaacttggggcaatggtgggaatacaaacctcgcttcaaaaggtgggtgggaagattgcaaaagatcccctgcatggaatgagactggcagacagcctaattcctggaataaacaacaccaacagcagcagcagcagccaccgccaccacagccagaggcttctggttcatggggaggcccacccccaccacctcaaggcaatgttcgaccttctaattccaactggagcagtgggccccaacctgcaacccctaaggatgatgaacccagtggttgggaggagccatccccacagtcaattagtcgaaaaatggacatcgatgatggcacttcagcttggggagaccctaacagttataactacaagaatgtgaacctttgggataagaattctcaagggggcccagcacctcgagaaccaaacctgcctaccccgatgaccggaaaatcagcatcagtctggagcaaaagcacaccacctgctccagataatgggacttcagcctggggtgagccaaatgaaagcagtcctgggtggggtgagatggatgatgcaggagcatcagccacaggctggggaaacacacctgccagcgctcccaatgccatgaaacccaattccaaatctatgcaagacggctggggggagagtgatggcccagtcacaggagctcgccatcctagctgggaagaggaagatgatggaggagtctggaacaccgccggctctcagggaagcacttcctcccacaactcagcaagctggggacaaggaggaaagaaacaaatgaagtgctcgataaaaggaaacaatgattcgtggatgaatcctcttgccaaacagttttcaaatatgggattgctgagtcaaactgaggataacccaagcagcaaaatggatttgtctgtagataagaaatttgatgtggacaagagaacaatgaatctcggggattttaatgatatcatgaggaaggatcgacctgggttccgtccacctaattccaaagacttgggaaccacagacagtgggccttattttgagaagctgactttgcctttctccaatcaagatgggtgccttggggatgaggctccctgctctcccttctccccttctcccagctacaagctgtctccctctggttccacactacccaacgtcagccttggagcaatcggcacagggctcaacccccaaaacttcgctgctagacaaggcggcagtcatggtttgtttggaaacagcacagcacagtcaagaggcctgcacactccagtgcagccactgagttcttctcctggtctccgggcgcaagtgcctccccagtttatctccccccaggtttctgcctcaatgctcaagcagttccccaacagtggcctgaatccaggtctctttaatgtggggccccagttatctcctcaacaaattgccatgctgagccagcttccacagattccccagtttcagttggcttgtcagcttcttctgcagcagcagcagcagcagcagttgctacagaaccagagaaagatctctcaagcagtgcgccagcagcaagagcagcagctggcaagaatggt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