LOCUS       NM_001444255            1643 bp    mRNA    linear   ROD 07-DEC-2025
DEFINITION  Rattus norvegicus H6 family homeobox 2 (Hmx2), transcript variant
            2, mRNA.
ACCESSION   NM_001444255 XM_039107601
VERSION     NM_001444255.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Zheng,S., Damoiseaux,R., Chen,L. and Black,D.L.
  TITLE     A broadly applicable high-throughput screening strategy identifies
            new regulators of Dlg4 (Psd-95) alternative splicing
  JOURNAL   Genome Res 23 (6), 998-1007 (2013)
   PUBMED   23636947
REFERENCE   2  (bases 1 to 1643)
  AUTHORS   Wang,W., Grimmer,J.F., Van De Water,T.R. and Lufkin,T.
  TITLE     Hmx2 and Hmx3 homeobox genes direct development of the murine inner
            ear and hypothalamus and can be functionally replaced by Drosophila
            Hmx
  JOURNAL   Dev Cell 7 (3), 439-453 (2004)
   PUBMED   15363417
REFERENCE   3  (bases 1 to 1643)
  AUTHORS   Wang,W., Chan,E.K., Baron,S., Van de Water,T. and Lufkin,T.
  TITLE     Hmx2 homeobox gene control of murine vestibular morphogenesis
  JOURNAL   Development 128 (24), 5017-5029 (2001)
   PUBMED   11748138
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 4, 2025 this sequence version replaced XM_039107601.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.827496.1,
                                           SRR26360194.2031277.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-506               JAXUCZ010000001.1  195754455-195754960
            507-1643            JAXUCZ010000001.1  195755809-195756945
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1643
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="H6 family homeobox 2"
                     /db_xref="GeneID:293538"
                     /db_xref="RGD:1565366"
     exon            1..506
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..1060
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="H6 homeo box 2"
                     /codon_start=1
                     /product="homeobox protein HMX2"
                     /protein_id="NP_001431184.1"
                     /db_xref="GeneID:293538"
                     /db_xref="RGD:1565366"
                     /translation="

MGSKEDVGKGCPAAGGVSSFTIQSILGGGPSEAPREPAGWPARKRSLSVSSEEEEPEEGWKAPACYCPDPHGPKEPSPKHHPPIPFPCLGTPKGSGGAGPAASERTPFLSPSHPDFKEEKERLLPAGSPSPGPERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVGMPLVFRDSSLLRVPVPRSLAFPAPLYYPSSNLSALPLYNLYNKLDY"

     misc_feature    686..856
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            507..1643
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggacgttggcaccggggctgggcgggctcatccagagcggggccggcagggacccgcgcgcagctgtccggtgcctgcgcgtcctggagcagaagggacgcccccccagcctcgtagccccctccccttgctttccctcccgcccctccccccgcctgcctgcccgcaccaccttccttccacccagccccgctctaaagggagttcttggtttcctccgatttcttatgaacccaggatgggcagcaaggaagatgtggggaagggatgtccggcggccggtggcgtctccagcttcaccatccagtccatcctgggcgggggcccctccgaggcaccgcgggagcccgccgggtggccagccaggaaacgcagcttgtctgtgtcctcggaggaggaggagccggaggaaggctggaaggctccggcttgctactgcccagatccgcacggccccaaggagccaagccctaagcaccatccccccatccctttcccttgcctgggtacccccaagggcagcggaggcgcagggcctgcggcctcggagcgcacgcctttcctttctccttctcacccggactttaaggaagagaaggagaggctcttgcccgcaggctcgccttctccgggcccggagcggccacgggacggcggtgcagagcgccaagccggagcggccaagaagaagacgcgcaccgtcttctcccgcagccaagtgtaccagctcgagtccaccttcgacatgaaacgctaccttagcagctcggagcgcgcttgcctcgcctccagcctgcagctcaccgagacccaggttaagacttggtttcagaatcgccgcaacaagtggaagcgacagctttccgccgagctagaggcggccaacatggcacacgcgtcggcgcagactctcgtgggcatgccgttggtatttcgggacagttcgctactgcgagtgccggtgccacgctctctcgcctttccggctccgctctattaccccagcagcaatctctcggccttaccgctctacaacctgtacaacaagcttgactactgacacgcccgctggctcccggggcgcctctggtcgcctgcagttgcctgcatagtccggcgcggtcggtatccttactggggctccggagcagagcggcgcgtgtccagaaatattaagaaatacaccatgtgtattcgttatgtcttatttatggcctcttccctactttttgggttttttgttttgttttgagtatttatccgcattcctcacaccagagcacctgctttctacacaaaaccaaaccaacacgccacgcgtatgaaactattttggaaggggagattctcgggtagtggtgggaaagggggttttgattggccggtagcaagaaaaaaaacatcagaaaaataccaacaaaaccaggtagtctttctcccatatatacacctgtatatgtatataaatagtgtacaaggacacaatctcagccgagcggagcccactaggacgttggccattgaaccaatcacttctctttattcccttcatcttgaggatgagtaggggtgaaacgaggagagtacagatctgtaaatatttttaaagagaaaaaaaataaaacgttttaaacatggttgct

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