LOCUS       NM_001443880             880 bp    mRNA    linear   ROD 20-NOV-2025
DEFINITION  Rattus norvegicus dynein regulatory complex subunit 8 (Drc8),
            transcript variant 2, mRNA.
ACCESSION   NM_001443880 XM_039090534
VERSION     NM_001443880.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Nov 20, 2025 this sequence version replaced XM_039090534.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.400979.1,
                                           SRR26360194.1088404.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               JAXUCZ010000013.1  92684344-92684467
            125-209             JAXUCZ010000013.1  92716241-92716325
            210-282             JAXUCZ010000013.1  92737495-92737567
            283-362             JAXUCZ010000013.1  92761371-92761450
            363-405             JAXUCZ010000013.1  92762191-92762233
            406-472             JAXUCZ010000013.1  92762329-92762395
            473-517             JAXUCZ010000013.1  92762627-92762671
            518-880             JAXUCZ010000013.1  92767862-92768224
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q25-q26"
     gene            1..880
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="dynein regulatory complex subunit 8"
                     /db_xref="GeneID:289280"
                     /db_xref="RGD:1308593"
     exon            1..124
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    58..60
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="upstream in-frame stop codon"
     CDS             94..633
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="isoform 2 is encoded by transcript variant 2;
                     EF-hand calcium-binding domain-containing protein 2;
                     dynein regulatory complex protein 8; EF-hand calcium
                     binding domain 2; EF-hand calcium-binding
                     domain-containing protein 2-like"
                     /codon_start=1
                     /product="dynein regulatory complex protein 8 isoform 2"
                     /protein_id="NP_001430809.1"
                     /db_xref="GeneID:289280"
                     /db_xref="RGD:1308593"
                     /translation="

MAEEKDPESTEAIVAELHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCSPTEGELHDFIAEVEEEEPTGYIRFEKFIPVMTTVLLEKRYRPIAEDVLLRAFEVLDPTKRGFLTKDELVKYMTEEGVLFPWRLPLELELHGEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVIDEN"

     misc_feature    157..618
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="calmodulin; Provisional; Region: PTZ00184"
                     /db_xref="CDD:185504"
     exon            125..209
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            210..282
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            283..362
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            363..405
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            406..472
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            473..517
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            518..880
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

accgcgcgtcgaggggcttcctccgcctcgtccccctcgcgcggcccgcagggtttgtgatgggatctcccaggcgacgggctccgcaccaagatggcggaggaaaaggacccggagagtacagaggcaatagtggcagaacttcataagaagatcaaagaggcgtttgaagtgtttgaccatgaatcgaataatacagtagatgtgagagagattgggacgattatcaggtcgttaggatgcagccccactgaaggagaactgcacgatttcattgctgaggtagaggaagaagaacccactgggtacattcgatttgaaaaatttattccagtgatgaccacagtacttctagaaaaaagatacagaccaattgctgaagatgtccttttgcgagctttcgaggttttggatccaactaaacgtgggtttctgactaaggatgaactagtcaagtacatgactgaggaaggagtgttgttcccatggaggctccctctggagctggagttacatggcgagcctttttcccaagaggaaatggaagaaatgttgtctgctgcaattgatcctgaatcaaacaccattaattacagagactacataacaatgatggtgatagatgaaaattaaatgctccaaagacttcttttttctccttttaagacaactgtaaacattcaatttctaattgaaaagatactttgaaaaattgtcctaatttttacattttatcttaaaatttctatatttagtgtctcatgatataattgtttcaaggtattttgtttactagagatgatcaatttaaaacataaattttttagatgaccagctttatggacagacaagttgattatttaaaaggaattatacagta

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