LOCUS       NM_001412904            1258 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 40 (Tmem40), transcript
            variant 2, mRNA.
ACCESSION   NM_001412904
VERSION     NM_001412904.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.19328.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680412, SAMN06680413
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                JAXUCZ010000004.1  150491860-150491895 c
            37-117              JAXUCZ010000004.1  150477404-150477484 c
            118-252             JAXUCZ010000004.1  150476645-150476779 c
            253-327             JAXUCZ010000004.1  150473591-150473665 c
            328-381             JAXUCZ010000004.1  150470819-150470872 c
            382-417             JAXUCZ010000004.1  150469241-150469276 c
            418-450             JAXUCZ010000004.1  150468666-150468698 c
            451-498             JAXUCZ010000004.1  150468333-150468380 c
            499-570             JAXUCZ010000004.1  150466209-150466280 c
            571-645             JAXUCZ010000004.1  150466036-150466110 c
            646-708             JAXUCZ010000004.1  150465470-150465532 c
            709-1258            JAXUCZ010000004.1  150464123-150464672 c
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1258
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /note="transmembrane protein 40"
                     /db_xref="GeneID:680858"
                     /db_xref="RGD:1587025"
     exon            1..36
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    18..20
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MSPGTPGKE"
     exon            37..117
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..728
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="transmembrane protein 40 isoform 2"
                     /protein_id="NP_001399833.1"
                     /db_xref="GeneID:680858"
                     /db_xref="RGD:1587025"
                     /translation="

MEASGSSSQSPNSSAVHRETEDLNHPETEFHKQHGKARERYERDKSSSSSSSSSSSSSSSSSSSSSSSSDSSDEDKHSRGPRKHRRKSHRDSSPGADHGELEVLKDELQLYGGAAGEMVLAGESGLRRRGSGSAEGEVEASQLNRLNIKKDDEFFHFVLLCFAIGALLVCYHYYSDWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN"

     misc_feature    363..722
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /note="Transmembrane protein 40 family; Region: TMEM40;
                     pfam15817"
                     /db_xref="CDD:464892"
     exon            118..252
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            253..327
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            328..381
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            382..417
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            418..450
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            451..498
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            499..570
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            571..645
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            646..708
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
     exon            709..1258
                     /gene="Tmem40"
                     /gene_synonym="RGD1306976"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctcgcattgctgctcacatgagcccagggactccagggaaagagatggaggcttcaggatcttcttctcagtctccaaacagcagtgcggtccacagagaaacagaagatctaaaccacccagagacagagttccacaagcaacatgggaaggcccgggaacgctatgagagagacaagtcttcctcctcatcctcctcctcctcttcctcctcttcctcctcttcctcctcatcttcttcctcctcctcagacagcagcgatgaggacaagcactccagaggtccgaggaaacacagaaggaagtcgcacagagacagctctcctggtgctgaccatggggaactggaggtgctgaaggacgagcttcagctctatggaggcgctgctggggaaatggtgcttgctggggagtcaggactccgaaggagaggttccggctcagcggagggagaagtggaggcctctcagttaaacagactgaacataaagaaggatgatgagtttttccattttgtccttctctgcttcgccattggagccttgctggtgtgctaccactactattcagactggttcatgtctcttggggttggtctgctcaccttcgcttctctggagaccatcggcatctacttcgggctggtgtaccggatccacagcgtacttcagggcttcatccccctccttcagaagttcaggctgccagggttcaggagaaccaactgagatcactgcccgacagcagctgagccagtccccaatgtgaccactgtaaccactgccaaacctgagcccagaatacagagtgacatgctggaagacactaggaggccacacaacaaagagctctttccttccgtgtgatctgagtgtcagctgatctgagtgggcaagctcttgttctgcagattagcacacagtctccatggggaagagagaaggcacagcatctgggtcagcaagaaagagctgggatgccattgctctcaggggtagcatgagtcttgggccttgcaggctggcatcttcgggcttgggtatctctggtgtcctcaggccatgctcatgaactcacagttccagcagagccatcttgggacagctatcctgaggcagggagctaccaggctgggtccccaggggaacctgcagataagatactggggaccaaagctgtagaccatcacccagtgaccaaccctgttgcccttggacttctaaaacccaaataaatattctattccctgtgctaaaaa

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