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Previous release (v1)
2025-04-20 10:31:00, GGRNA.v2 : RefSeq release 229 (Mar, 2025)
LOCUS NM_001401347 3806 bp mRNA linear ROD 31-MAR-2024
DEFINITION Rattus norvegicus kinesin-associated protein 3 (Kifap3), mRNA.
ACCESSION NM_001401347 XM_008769623
VERSION NM_001401347.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 3806)
AUTHORS Phang,H.Q., Hoon,J.L., Lai,S.K., Zeng,Y., Chiam,K.H., Li,H.Y. and
Koh,C.G.
TITLE POPX2 phosphatase regulates the KIF3 kinesin motor complex
JOURNAL J Cell Sci 127 (Pt 4), 727-739 (2014)
PUBMED 24338362
REFERENCE 2 (bases 1 to 3806)
AUTHORS Tsai,J.W., Lian,W.N., Kemal,S., Kriegstein,A.R. and Vallee,R.B.
TITLE Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear
migration in neural stem cells
JOURNAL Nat Neurosci 13 (12), 1463-1471 (2010)
PUBMED 21037580
REMARK GeneRIF: RNA interference screening of kinesin genes identifies
Kif1a, a member of the kinesin-3 family, as the motor for basally
directed nuclear movement in neural stem cells.
REFERENCE 3 (bases 1 to 3806)
AUTHORS Insinna,C., Humby,M., Sedmak,T., Wolfrum,U. and Besharse,J.C.
TITLE Different roles for KIF17 and kinesin II in photoreceptor
development and maintenance
JOURNAL Dev Dyn 238 (9), 2211-2222 (2009)
PUBMED 19384852
REFERENCE 4 (bases 1 to 3806)
AUTHORS Choi,J., Ha,C.M., Choi,E.J., Jeong,C.S., Park,J.W., Baik,J.H.,
Park,J.Y., Costa,M.E., Ojeda,S.R. and Lee,B.J.
TITLE Kinesin superfamily-associated protein 3 is preferentially
expressed in glutamatergic neurons and contributes to the
excitatory control of female puberty
JOURNAL Endocrinology 149 (12), 6146-6156 (2008)
PUBMED 18703627
REMARK GeneRIF: Results support the view that decreased KAP3 synthesis
diminishes GnRH output and delays female sexual development by
compromising hypothalamic release of glutamate.
REFERENCE 5 (bases 1 to 3806)
AUTHORS Haraguchi,K., Hayashi,T., Jimbo,T., Yamamoto,T. and Akiyama,T.
TITLE Role of the kinesin-2 family protein, KIF3, during mitosis
JOURNAL J Biol Chem 281 (7), 4094-4099 (2006)
PUBMED 16298999
REFERENCE 6 (bases 1 to 3806)
AUTHORS Teng,J., Rai,T., Tanaka,Y., Takei,Y., Nakata,T., Hirasawa,M.,
Kulkarni,A.B. and Hirokawa,N.
TITLE The KIF3 motor transports N-cadherin and organizes the developing
neuroepithelium
JOURNAL Nat Cell Biol 7 (5), 474-482 (2005)
PUBMED 15834408
REMARK Erratum:[Nat Cell Biol. 2005 Jun;7(6):637]
REFERENCE 7 (bases 1 to 3806)
AUTHORS Baker,S.A., Freeman,K., Luby-Phelps,K., Pazour,G.J. and
Besharse,J.C.
TITLE IFT20 links kinesin II with a mammalian intraflagellar transport
complex that is conserved in motile flagella and sensory cilia
JOURNAL J Biol Chem 278 (36), 34211-34218 (2003)
PUBMED 12821668
REFERENCE 8 (bases 1 to 3806)
AUTHORS Takakura,A., Miyoshi,J., Ishizaki,H., Tanaka,M., Togawa,A.,
Nishizawa,Y., Yoshida,H., Nishikawa,Si. and Takai,Y.
TITLE Involvement of a small GTP-binding protein (G protein) regulator,
small G protein GDP dissociation stimulator, in antiapoptotic cell
survival signaling
JOURNAL Mol Biol Cell 11 (5), 1875-1886 (2000)
PUBMED 10793158
REFERENCE 9 (bases 1 to 3806)
AUTHORS Yamazaki,H., Nakata,T., Okada,Y. and Hirokawa,N.
TITLE Cloning and characterization of KAP3: a novel kinesin
superfamily-associated protein of KIF3A/3B
JOURNAL Proc Natl Acad Sci U S A 93 (16), 8443-8448 (1996)
PUBMED 8710890
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
JAXUCZ010000013.1.
On Feb 9, 2022 this sequence version replaced XM_008769623.3.
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##Evidence-Data-START##
Transcript exon combination :: SRR26360194.249893.1,
SRR26360186.2855678.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA5760383, SAMEA5760386
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on conservation, expression
##RefSeq-Attributes-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-228 JAXUCZ010000013.1 78671301-78671528
229-360 JAXUCZ010000013.1 78674441-78674572
361-515 JAXUCZ010000013.1 78678754-78678908
516-571 JAXUCZ010000013.1 78680693-78680748
572-713 JAXUCZ010000013.1 78681953-78682094
714-813 JAXUCZ010000013.1 78686958-78687057
814-938 JAXUCZ010000013.1 78688402-78688526
939-1037 JAXUCZ010000013.1 78690457-78690555
1038-1216 JAXUCZ010000013.1 78698501-78698679
1217-1379 JAXUCZ010000013.1 78702793-78702955
1380-1480 JAXUCZ010000013.1 78726068-78726168
1481-1589 JAXUCZ010000013.1 78733409-78733517
1590-1702 JAXUCZ010000013.1 78734812-78734924
1703-1868 JAXUCZ010000013.1 78741221-78741386
1869-1994 JAXUCZ010000013.1 78742164-78742289
1995-2093 JAXUCZ010000013.1 78744673-78744771
2094-2179 JAXUCZ010000013.1 78747809-78747894
2180-2369 JAXUCZ010000013.1 78766525-78766714
2370-2469 JAXUCZ010000013.1 78770656-78770755
2470-3806 JAXUCZ010000013.1 78796485-78797821
FEATURES Location/Qualifiers
source 1..3806
/organism="Rattus norvegicus"
/mol_type="mRNA"
/strain="BN"
/db_xref="taxon:10116"
/chromosome="13"
/map="13q22"
gene 1..3806
/gene="Kifap3"
/note="kinesin-associated protein 3"
/db_xref="GeneID:289168"
/db_xref="RGD:1305191"
exon 1..228
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
misc_feature 140..142
/gene="Kifap3"
/note="upstream in-frame stop codon"
CDS 197..2578
/gene="Kifap3"
/codon_start=1
/product="kinesin-associated protein 3"
/protein_id="NP_001388276.1"
/db_xref="GeneID:289168"
/db_xref="RGD:1305191"
/translation="
MQSEDARYLKRKVKGGNIDVHPSEKALIVQYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLNEVEQLLYYLQNRRDSLSGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDLPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSHFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDLENQTLRKDYDKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNENYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKLKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISSDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPFLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLITSEGALSPDFFNDFHLQNGDVVGQHSFPGSLGMDGFGQPVGILGRPATAYGFRPDEPYYYSFGSR"
misc_feature 233..2356
/gene="Kifap3"
/note="Kinesin-associated protein (KAP); Region: KAP;
pfam05804"
/db_xref="CDD:253396"
exon 229..360
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 361..515
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 516..571
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 572..713
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 714..813
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 814..938
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 939..1037
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1038..1216
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1217..1379
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1380..1480
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1481..1589
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1590..1702
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1703..1868
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1869..1994
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 1995..2093
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 2094..2179
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 2180..2369
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 2370..2469
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
exon 2470..3806
/gene="Kifap3"
/inference="alignment:Splign:2.1.0"
ORIGIN
agtgttttggggcccaggagctgtgggaggggccggcggcctcaccgtggtaaccgctgcgccgccgctgccccgccttgcaggcctcgggactgtcaccgcctctgctttgagggtaccttggccgggtccccggaagtagccctcccagatcctcagaccctcccattctccccacgccgctgctgccgccgccatgcaaagcgaggacgccagatacctcaaaaggaaagttaaaggggggaatattgatgtacatccatcagaaaaagctcttatcgttcagtatgaagtggaggctaccattcttggagaaatgggggatcccatgttgggagaacgaaaggaatgccaaaaaatcatccgcctgaagagtctcaatgctaacacagacataacctctctggcccggaaagtggttgaagaatgtaaactcatccatccctcaaagctcaatgaggtggaacagcttttgtactatctacagaaccgccgtgactcattgtcaggaaaagaaaagaaagaaaagtctagcaagcctaaagacccacctccttttgaagggatggagattgacgaggtggccaacattaacgacatggatgagtacattgagctcttgtatgaagaccttccagacaaggtccggggctcggccttgatcctacagcttgctcgaaatcctgataacctggaagagctattattaaatgaaactgccctgggtgcgctagcaagagtcctgagagaagactggaaacaaagcgttgagttagctacaaatatcatttatatcttcttttgcttctctagcttttctcattttcatggactcatcactcactataaaattggagcactgtgtatgaatatcattgatcatgagttaaaaagacacgagctttggcaagaagaactttctaagaagaagaaagctgttgatgaagaccttgaaaatcaaactttgagaaaggattatgacaaaacctttaaaaaataccagggacttgtggtaaaacaagagcagctcttgagagttgctctctatttgcttctgaatcttgcggaggacacgcgtacggaactgaagatgaggaacaagaatatcgttcacatgttggtgaaggctcttgatcgggacaattttgagctgctcattctagtcgtgtcattcttaaagaaactcagtatttttatggagaataaaaatgacatggtagagatggatattgttgaaaaactggtaaaaatgatcccctgtgagcatgaagatcttctgaacatcaccctccggctcctcttaaacctctcatttgacacaggcctgaggaacaagatggtacaagttggactcctcccgaagctcactgcactcttgggcaatgaaaactacaaacaaatagcgatgtgtgtgctttaccacataagcatggatgaccgcttcaagtccatgtttgcatatactgactgcataccacagttaatgaagatgctctttgaatgttcagatgaacgaattgacttggagctgatttctttctgcattaatcttgctgctaacaagagaaatgttcagctcatctgtgaaggaaatgggctgaagatgctcatgaaaagagcgctgaagctcaaggaccctctgctgatgaagatgatcaggaacatctcccagcatgatggacccactaagaatttgttcattgattatgttggggaccttgcagcccagatttccagtgatgaagaggaggagtttgtaatcgagtgtttgggaacactggcgaatctgacaatcccagatctagactgggaactggttctgaaggagtacaagctggttccattcctcaaagacaagctaaagccaggtgctgcagaagatgaccttgttttagaagtggtcataatgattggaacagtatctatggatgactcttgtgctgcactgctagctaaatctgggataatcccagcactcatcgaactgctgaatgctcaacaagaagatgatgaatttgtgtgtcagataatttatgtcttctatcagatggttttccatcaggccacaagagatgtcataatcaaagaaacacaagctccagcatatctcatagacctgatgcatgataaaaataatgaaatccggaaagtctgtgataacacgttagatattatcgcagagtatgatgaagagtgggcaaagaaaattcagagtgagaagtttcgctggcataactctcagtggttggagatggtggagagtcgtcagatggatgagagtgagcagtacttatatggtgatgaccggattgagccgtacatccatgaaggagacattcttgaaaggcctgacctcttctacaactcagatggactaatcacctctgaaggagctctaagtccagacttcttcaatgactttcacctccagaatggagacgtggttggacagcactcatttcctggcagccttggaatggatggctttggtcagccagtgggaatcctcggacgccccgccaccgcatatggattccgccctgacgagccttactactacagctttgggtctcgataaaatcaccctcccatgtataactcggctgaggagagatctgtgtgctgtgggctaaccttgaatcttgacttaataatgcatgttgttctcctgtggggctgcgttgcttatttctccccgctgttagcttcgggttagcgctaacctcacgcctttcgttgacatggttgatgctccaccgttcacgcatccagccacatcttgaggtgaatgacatttcccatgagactgctgcagagctgctagcctggaaaagcagatgctacaccatttacactacgtgactaatctctattaaaaggtggcatgcccgcaaaggagtgggccaaagtcatgtgttcatactgtgtttcacaggaaccactcatgtacatgggatacacatactttttttttttttgcgttctctttctttttataaactcctagtgtttcgtgtgagccatgctgcctttaccttttattttaaatgaacctcattctttttatcccatgctgtgtctggaagtttctttcacaaagtttttaactatatgagttttttaacttaacagtgaacacatgctataagtaagttatgcacgtatagactagcgagtgacccagagtcctgacatgttaactgcagcagacactgaggagcgggatcctctgtgagtgcagcaggagcaacactgagcttgtaagttttgttcttctgagatgtacgatgtaaactgtgaagatgctaagtatttttgccttacctaagaaaattaaggaaaggactctctgttcacttaagttagaagtgggtggtgggaataaaagggacacaatgattaataatgggttttgaaaataattcattgattgtaaaatactgaaaactttccttgagaaaccaagcaaatgaatccaatatgagcacagatcatctcctactgaaggaaacatacaattcagaacagtgcaggtcaaggggaagatttctgcttttaaatttaaaatcccactgatccaagtatactgtttaccttaattcacacgtttcacagagtcctggtgctgggacggtcatctgcctgagaaatgtaaagctaagcaacaggtgtgctctcacctgacacacacggtagtgtatgatctgggacggcgtctgtgtgtgctctacaactctgaatgcatgcagctattgtctttgtttccctttacccacaaaatattaaagccagaaaggttcgaatca
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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