LOCUS       NM_001395739            1833 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus LRR binding FLII interacting protein 2 (Lrrfip2),
            transcript variant 2, mRNA.
ACCESSION   NM_001395739 XM_006243957
VERSION     NM_001395739.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1833)
  AUTHORS   Dai,P., Jeong,S.Y., Yu,Y., Leng,T., Wu,W., Xie,L. and Chen,X.
  TITLE     Modulation of TLR signaling by multiple MyD88-interacting partners
            including leucine-rich repeat Fli-I-interacting proteins
  JOURNAL   J Immunol 182 (6), 3450-3460 (2009)
   PUBMED   19265123
REFERENCE   2  (bases 1 to 1833)
  AUTHORS   Fong,K.S. and de Couet,H.G.
  TITLE     Novel proteins interacting with the leucine-rich repeat domain of
            human flightless-I identified by the yeast two-hybrid system
  JOURNAL   Genomics 58 (2), 146-157 (1999)
   PUBMED   10366446
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Aug 3, 2021 this sequence version replaced XM_006243957.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ233539.1, SRR26643285.33058.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-272               JAXUCZ010000008.1  119969908-119970179
            273-344             JAXUCZ010000008.1  119971436-119971507
            345-488             JAXUCZ010000008.1  119989208-119989351
            489-575             JAXUCZ010000008.1  120006714-120006800
            576-620             JAXUCZ010000008.1  120035573-120035617
            621-737             JAXUCZ010000008.1  120037071-120037187
            738-809             JAXUCZ010000008.1  120040110-120040181
            810-980             JAXUCZ010000008.1  120048360-120048530
            981-1073            JAXUCZ010000008.1  120053192-120053284
            1074-1206           JAXUCZ010000008.1  120061070-120061202
            1207-1256           JAXUCZ010000008.1  120062757-120062806
            1257-1377           JAXUCZ010000008.1  120066310-120066430
            1378-1457           JAXUCZ010000008.1  120069165-120069244
            1458-1562           JAXUCZ010000008.1  120070326-120070430
            1563-1833           JAXUCZ010000008.1  120071000-120071270
FEATURES             Location/Qualifiers
     source          1..1833
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1833
                     /gene="Lrrfip2"
                     /note="LRR binding FLII interacting protein 2"
                     /db_xref="GeneID:301035"
                     /db_xref="RGD:1306234"
     exon            1..272
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            273..344
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            345..488
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    387..389
                     /gene="Lrrfip2"
                     /note="upstream in-frame stop codon"
     CDS             399..1673
                     /gene="Lrrfip2"
                     /note="isoform 2 is encoded by transcript variant 2;
                     leucine-rich repeat flightless-interacting protein 2; LRR
                     FLII-interacting protein 2; leucine rich repeat (in FLII)
                     interacting protein 2"
                     /codon_start=1
                     /product="leucine-rich repeat flightless-interacting
                     protein 2 isoform 2"
                     /protein_id="NP_001382668.1"
                     /db_xref="GeneID:301035"
                     /db_xref="RGD:1306234"
                     /translation="

MGTPGSGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQRELDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIHDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPESTPNGDVNHEPVVGAITAVSQEAAQVLESAGEGPLDVRLRKLAEEKDELLSQIRKLKLQLEEERQKCSRNDGMSGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDIATLEQSISRLEGQVLRYKTAAENAEKIEDELKAEKRKLQRELRTAQDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ"

     misc_feature    537..1445
                     /gene="Lrrfip2"
                     /note="LRRFIP family; Region: LRRFIP; pfam09738"
                     /db_xref="CDD:462869"
     misc_feature    <1377..>1643
                     /gene="Lrrfip2"
                     /note="Possible nuclease of RNase H fold, RuvC/YqgF family
                     [General function prediction only]; Region: COG2433"
                     /db_xref="CDD:441980"
     exon            489..575
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            576..620
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            621..737
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            738..809
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            810..980
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1073
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1206
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1256
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..1377
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1457
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1562
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1833
                     /gene="Lrrfip2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ccctctgccccgccaccgccgcagctgcagccgccgctcgggctgcggctcatcccgggttgcgttcgccgtgtcggccgcggcgcgaagggcgccctgagtgtgactacacggtcgtccgcagcgcgaggagcccttcttttgcctccctgcggcccgcggggtggacggtgcggggacagagtgtggccgccgctcccctctcccggctccggagcggccgatctggcccttccgggcggcgccgcagcctcatcccgcgccacacgcagatgtgggaagacaaatgaagggatttagaaaccaaataaatgccagtggaaaggagagctaccatcactaagtgctgaacacgagtaaactcattttcagagttaaaaaattattaaaaaaacaagatggggactcctggttctggaaggaaaagaacaccagtgaaagatcgattttctgcagaagatgaagctttgagtaacatcgccagagaggctgaagcaaggctagcagcaaagcgggccgccagggcagaagcaagagacatccgcatgagggaactggaacgacagcagagagagttggatgaaaaatctgacaaacagtatgctgaaaattacacaagaccctcatctcgaaattctgcgtcagcaacaacacctctaagcggaaactcatccagacggggtagtggggacaccagtagtttaatagacccagacacctcgttaagtgaactgcgggacatctatgacctgaaggaccagatacatgatgtagaagggagatacatgcaggggcttaaggaactgaaggagtctttgtctgaagtagaagagaagtacaagaaagccatggtgtccaatgcacaactagacaacgagaagaacaatctgatctaccaggtggacaccctcaaggacgtcatcgaggagcaggaggagcagatggcagagttctatagagaaaacgaagagaaatcaaaggagttggaacggcagaaacatatgtgcagtgtgctgcagcataagatggatgaactgaaagagggccttcggcagagggacgagctcatcgagaagcacggcttagttataatcccagagagtactcccaatggcgacgtcaatcatgagcctgtggttggagccattactgctgtgtctcaggaagctgctcaggtcttggagtcagcaggagaagggccactagatgtgaggctgcggaagcttgctgaggaaaaggacgagctcctgtcacagattagaaaactgaagctccagttagaggaagaacggcagaagtgttccaggaatgatggcatgtccggggacctggcagggctgcagaacggctccgacttgcagttcatcgagatgcagagagacgccaatagacaaattagtgaatacaaattcaagctttcgaaagcagaacaagacatagctaccttggaacaaagtatcagccggcttgaggggcaggtgctgaggtacaagactgccgctgagaacgctgagaagattgaagacgagctgaaagcagagaagaggaagctacagcgagagctacggacagcacaggacaagatcgaggagatggagatgaccaacagccacctggcaaagcggctagagaagatgaaggccaacaggacagcccttctagcccagcagtaggaggcagcccctccacctgggtgctgctctgagggctttgctgggagatactgactcttgtacattgacacagccccttccagtactgttttgagtcttgtcattaaacagccacctttgtattttataatttatgagaatgaagcaggtttaatcgtta

//