LOCUS       NM_001106152            3382 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 25 member 2 (Slc25a2),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001106152 XM_001065727 XM_226032
VERSION     NM_001106152.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3382)
  AUTHORS   Fiermonte,G., Dolce,V., David,L., Santorelli,F.M., Dionisi-Vici,C.,
            Palmieri,F. and Walker,J.E.
  TITLE     The mitochondrial ornithine transporter. Bacterial expression,
            reconstitution, functional characterization, and tissue
            distribution of two human isoforms
  JOURNAL   J Biol Chem 278 (35), 32778-32783 (2003)
   PUBMED   12807890
REFERENCE   2  (bases 1 to 3382)
  AUTHORS   Camacho,J.A., Rioseco-Camacho,N., Andrade,D., Porter,J. and Kong,J.
  TITLE     Cloning and characterization of human ORNT2: a second mitochondrial
            ornithine transporter that can rescue a defective ORNT1 in patients
            with the hyperornithinemia-hyperammonemia-homocitrullinuria
            syndrome, a urea cycle disorder
  JOURNAL   Mol Genet Metab 79 (4), 257-271 (2003)
   PUBMED   12948741
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Dec 20, 2021 this sequence version replaced NM_001106152.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR26360172.2477039.1,
                                        SRR26360181.47587.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG   :: upstream AUG and CDS
                                                  extension is not conserved
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3382              JAXUCZ010000018.1  29704182-29707563   c
FEATURES             Location/Qualifiers
     source          1..3382
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..3382
                     /gene="Slc25a2"
                     /note="solute carrier family 25 member 2"
                     /db_xref="GeneID:291640"
                     /db_xref="RGD:1310667"
     exon            1..3382
                     /gene="Slc25a2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    51..53
                     /gene="Slc25a2"
                     /note="upstream in-frame stop codon"
     misc_feature    81..83
                     /gene="Slc25a2"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MGAYRDLASGDTLGSVEEHEIHPAIQAAIDLTAGAAGAAACVLTGQPFDTVKVK"
     CDS             243..1040
                     /gene="Slc25a2"
                     /note="solute carrier family 25 (mitochondrial carrier,
                     ornithine transporter) member 2"
                     /codon_start=1
                     /product="mitochondrial ornithine transporter 2"
                     /protein_id="NP_001099622.1"
                     /db_xref="GeneID:291640"
                     /db_xref="RGD:1310667"
                     /translation="

MQTFPYMYKGLADCFLKTYNQVGVHGLYRGTSPALLAYVAQGSVLFLCYGFCQQFVRKVARVEQSAELNDFETATAGSLASAFAALVLCPTELVKCRLQTMHEMRVAGKTKHSHNTIWSMVKSIFMKDGPLGFYRGLSTTLAQEIPGYFFYFGGYEISRSFFASGGSKDELGPVPLMLSGSFAGVCLWLIIFPVDCIKSRIQVLSMFGKPAGLIKTFINVVRNEGILALYSGLKATLIRAIPSNAALFVVYEYSRKMMMNVVEEY"

     misc_feature    <243..416
                     /gene="Slc25a2"
                     /note="Mitochondrial carrier protein; Region: Mito_carr;
                     pfam00153"
                     /db_xref="CDD:395101"
     misc_feature    441..728
                     /gene="Slc25a2"
                     /note="Mitochondrial carrier protein; Region: Mito_carr;
                     pfam00153"
                     /db_xref="CDD:395101"
     misc_feature    747..1022
                     /gene="Slc25a2"
                     /note="Mitochondrial carrier protein; Region: Mito_carr;
                     pfam00153"
                     /db_xref="CDD:395101"
ORIGIN      

attccccagcggccagagagtgcggtggcccaaggctttggctttatctttgacaaggagacaggtccgcagtggggaccatgggcgcctacagagacttggcttctggcgacaccctcgggagtgtggaggaacatgaaatccaccctgccatccaagccgccatagacctcactgccggcgcagcaggggccgcagcgtgtgtgctgaccgggcagcccttcgacaccgtaaaagtaaagatgcagacatttccctacatgtacaaaggcctcgctgactgtttcctaaagacatacaaccaagtgggtgtccacggcctttacaggggaaccagtcctgcactgttagcctatgtcgcccagggctctgtcctatttttgtgctatggcttttgccaacagtttgtcaggaaagtggcaagagtggagcagagtgcagaactgaacgactttgagactgccactgctgggtcactggcttctgcatttgctgcgctggtcctctgccccactgagcttgtgaagtgtcggctgcagactatgcatgaaatgagggtggcagggaagacaaaacacagccacaacacaatttggtctatggttaagagtatcttcatgaaggatggtcccttaggcttctatcgtggactctcaaccactcttgctcaggaaatacctggatacttcttctactttgggggctatgaaatcagtcgatcattttttgcgtcagggggatcaaaggatgaactaggtcctgtccctttgatgttaagtggaagctttgctggggtttgtctctggcttatcatattcccagtagactgcattaaatccagaatccaggttctttctatgtttgggaagcctgcaggattaattaaaacctttataaatgttgtgagaaatgaaggaatattagccttgtattctggattgaaagccactctgattcgagccatcccttccaatgctgctctatttgtggtttatgaatacagcagaaagatgatgatgaatgtggtagaagaatactgaagtgtcttgatgaatccttgtctgagcacaccaatgtgaggaccacagctctacatgtcaaagagttcaagaccaacatggagttatctttgactgggaatttcgggtttgtcttcccttcctcagatctcaaaccttgtggagagatctttatagcatatgttttttttctgcagtccttctgaaataggaaaatcactacttttgctgatggtgggatctacagggtgaacccaagaccctatgtacttaattatcagggcttcttcataaatctatatatgcatcttgaatggtggttatgtgttgtgagtgaaacataatttggtgctgttcagtgtcaagtatcaccaaaatatcttgaggtgatcatgcttcatgtttataggtattgcttaattcattcaagatgtgggttatggtttgaaacctctttaatgtgcactgcattaggccgttaaggtttttttttttttttttttaacgtctttaggtgagcaccaacacatttatgctgatttctaagaagagattgtacctgtgtaccagcatggcttccgcattcgagtaaaatttcataataggcatcctggattttttatgctgtccttagtgtggttaaagtatagttagttatattctaccagcactggtattgttaggtggggcaatgagtatcagagaagactttgggaagctgtgtggtctttacctgcattatttcctcattcttctcttccaaaggtgtcaggctttagattgaggaaggagctaaagggatgggattatatattgtgctttgatgatccatgtagatggagagaattctaataactccttgcctctgggtactggcctggacaggaattcacagtgttgggttggttcactttaggtctctcatcgttctccataccatcacccatttccccaggaaacaaagtaaagaaggcaagagtaggtttggttctgttcggtgacagagtaagagtcctgctagatgaagtcatcacttaggcaggactagtgtgcacttagtagtacatcacagtaagcaatgtgaaaggggtgacttaacccctgaagttcaccttgggtccataactgcttcagtgtggtcagtgttttagttttctaaatttggttctggtggtcagtgaaccttaaatgactggatttacaatataaaacaatggaccataagaaaagccattttactaaactctacgtatgcatataagcacagactatctcccaataaaactcccaaacacaccaaaatgagatgagtccccttccccaaattaaaattcagtttacctccaacagacctggaattaagcagatgttcatggaccatatgattttagagtcattctttataccaataaagtaagcttcgtctgtgttgctacaagatcaacagggtcttttcaataacaggtgttgatacctatggagctgaaagaaggtgaggtaccagtttaatagtatgtgtgccctgtgccaggcctttaacttcctttttaaaacccactaagccaaactatagttccagatgcaagattcaagttaattagaagatgacaaagaagccctgctggggatagttagcaagatgtctctcaatattacacacagtctgcttaggatctatagttgtttttttttttttttcccatatatttttttctatctgaagccatttgctagtttaattataagttgtttctgtgtgtaagttctgtgcaccacactttatggtcagtgtagtcctccagcatatagcatctatgagctggcctggaagctctcctttcagcacacttgcttctcacatactatacattaaacgtttaaatgccttcagtagaaatcatatgaagcaagcaagagtgaatgtgagtagaaggaaatagtcacacttttccggtttaattaacccttggtttaacttttgggtacattttgtatcctttcagatctctaggttagacagcagttaagatatgaacagtggaagtggctggggtcaagctctgttgtttaatcttagctctggggcgggacaggaaacctgggctcgctgaaacgcagttaggagaccaggtcatgcaattttgtgactaggtcttatgacctggtcttgtgaccaatattatgggaaatcctggtttgagcagttaatctatatgagatcaaccttccaccaatcaaaaggaaggatgtgaccatgtgacataggaaatgttttaccacaactggagatcctatcctcagaacttcactggtctgtgagagcaaatatttactcttaataaacttcactttattctaatgaa

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