LOCUS       NM_001105977             757 bp    mRNA    linear   ROD 20-NOV-2025
DEFINITION  Rattus norvegicus dynein regulatory complex subunit 8 (Drc8),
            transcript variant 1, mRNA.
ACCESSION   NM_001105977 XM_001059936 XM_213950
VERSION     NM_001105977.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Nov 20, 2025 this sequence version replaced NM_001105977.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AW916511.1, SRR26360190.2850048.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               JAXUCZ010000013.1  92684344-92684467
            125-204             JAXUCZ010000013.1  92716241-92716320
            205-284             JAXUCZ010000013.1  92761371-92761450
            285-327             JAXUCZ010000013.1  92762191-92762233
            328-394             JAXUCZ010000013.1  92762329-92762395
            395-757             JAXUCZ010000013.1  92767862-92768224
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q25-q26"
     gene            1..757
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="dynein regulatory complex subunit 8"
                     /db_xref="GeneID:289280"
                     /db_xref="RGD:1308593"
     exon            1..124
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    58..60
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="upstream in-frame stop codon"
     CDS             94..510
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="isoform 1 is encoded by transcript variant 1;
                     EF-hand calcium-binding domain-containing protein 2;
                     dynein regulatory complex protein 8; EF-hand calcium
                     binding domain 2; EF-hand calcium-binding
                     domain-containing protein 2-like"
                     /codon_start=1
                     /product="dynein regulatory complex protein 8 isoform 1"
                     /protein_id="NP_001099447.1"
                     /db_xref="GeneID:289280"
                     /db_xref="RGD:1308593"
                     /translation="

MAEEKDPESTEAIVAELHKKIKEAFEVFDHESNNTVDVEEEEPTGYIRFEKFIPVMTTVLLEKRYRPIAEDVLLRAFEVLDPTKRGFLTKDELVKYMTEEGEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVIDEN"

     misc_feature    157..495
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /note="calmodulin; Provisional; Region: PTZ00184"
                     /db_xref="CDD:185504"
     exon            125..204
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            205..284
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            285..327
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            328..394
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
     exon            395..757
                     /gene="Drc8"
                     /gene_synonym="Efcab2; RGD1308593"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

accgcgcgtcgaggggcttcctccgcctcgtccccctcgcgcggcccgcagggtttgtgatgggatctcccaggcgacgggctccgcaccaagatggcggaggaaaaggacccggagagtacagaggcaatagtggcagaacttcataagaagatcaaagaggcgtttgaagtgtttgaccatgaatcgaataatacagtagatgtagaggaagaagaacccactgggtacattcgatttgaaaaatttattccagtgatgaccacagtacttctagaaaaaagatacagaccaattgctgaagatgtccttttgcgagctttcgaggttttggatccaactaaacgtgggtttctgactaaggatgaactagtcaagtacatgactgaggaaggcgagcctttttcccaagaggaaatggaagaaatgttgtctgctgcaattgatcctgaatcaaacaccattaattacagagactacataacaatgatggtgatagatgaaaattaaatgctccaaagacttcttttttctccttttaagacaactgtaaacattcaatttctaattgaaaagatactttgaaaaattgtcctaatttttacattttatcttaaaatttctatatttagtgtctcatgatataattgtttcaaggtattttgtttactagagatgatcaatttaaaacataaattttttagatgaccagctttatggacagacaagttgattatttaaaaggaattatacagta

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