LOCUS       NM_001103362            3589 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus NudC domain containing 3 (Nudcd3), transcript
            variant 2, mRNA.
ACCESSION   NM_001103362
VERSION     NM_001103362.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3589)
  AUTHORS   Asante,D., Stevenson,N.L. and Stephens,D.J.
  TITLE     Subunit composition of the human cytoplasmic dynein-2 complex
  JOURNAL   J Cell Sci 127 (Pt 21), 4774-4787 (2014)
   PUBMED   25205765
REFERENCE   2  (bases 1 to 3589)
  AUTHORS   Shao,C.Y., Zhu,J., Xie,Y.J., Wang,Z., Wang,Y.N., Wang,Y., Su,L.D.,
            Zhou,L., Zhou,T.H. and Shen,Y.
  TITLE     Distinct functions of nuclear distribution proteins LIS1, Ndel1 and
            NudCL in regulating axonal mitochondrial transport
  JOURNAL   Traffic 14 (7), 785-797 (2013)
   PUBMED   23551859
  REMARK    GeneRIF: knocking down both Ndel1 and NudCL almost blocked
            retrograde mitochondrial axonal transport.
            Erratum:[Traffic. 2013 Oct;14(10):1105-8]
REFERENCE   3  (bases 1 to 3589)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Mar 30, 2023 this sequence version replaced NM_001103362.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107925.1, SRR26360186.819920.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840117, SAMN16676811
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               JAXUCZ010000014.1  85272640-85272883   c
            245-567             JAXUCZ010000014.1  85265967-85266289   c
            568-700             JAXUCZ010000014.1  85225877-85226009   c
            701-844             JAXUCZ010000014.1  85209622-85209765   c
            845-3589            JAXUCZ010000014.1  85200810-85203554   c
FEATURES             Location/Qualifiers
     source          1..3589
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..3589
                     /gene="Nudcd3"
                     /note="NudC domain containing 3"
                     /db_xref="GeneID:100125378"
                     /db_xref="RGD:1642416"
     exon            1..244
                     /gene="Nudcd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..952
                     /gene="Nudcd3"
                     /note="isoform 2 is encoded by transcript variant 2; nudC
                     domain-containing protein 3; nudC domain-containing
                     protein 3-like"
                     /codon_start=1
                     /product="nudC domain-containing protein 3 isoform 2"
                     /protein_id="NP_001096832.1"
                     /db_xref="GeneID:100125378"
                     /db_xref="RGD:1642416"
                     /translation="

MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPTDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRKKELEEKIRKKEEEAKAVAAATAEKEAVPVPVQEVEIDATTALSGPREVEKEELPGPQGPERKVTHGSEEAEAPGTASSAAEGPKDPPVLPRIQEQFQKNPDSYNGAIRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSGSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKCVLVPSWKERPTTFPLAQTQSHGQLRGVKPSSLGTVLP"

     misc_feature    77..253
                     /gene="Nudcd3"
                     /note="N-terminal conserved domain of Nudc; Region:
                     Nudc_N; pfam14050"
                     /db_xref="CDD:464073"
     misc_feature    608..>847
                     /gene="Nudcd3"
                     /note="The alpha-crystallin-Hsps_p23-like superfamily
                     includes the alpha-crystallin domain (ACD) of
                     alpha-crystallin-type small heat shock proteins (sHsps)
                     and a similar domain found in p23-like proteins. sHsps are
                     small stress induced proteins with monomeric...; Region:
                     alpha-crystallin domain (ACD) found in
                     alpha-crystallin-type small heat shock proteins, and a
                     similar domain found in p23 (a cochaperone for Hsp90) and
                     in other p23-like proteins.; cl00175"
                     /db_xref="CDD:469641"
     exon            245..567
                     /gene="Nudcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            568..700
                     /gene="Nudcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            701..844
                     /gene="Nudcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            845..3589
                     /gene="Nudcd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agccggtgtgaggcggtgcccactgtgttcgcgtccctcgggcagtagagccatggagcccggggctgctgagctttatgaccaggccctgctgggcatcctgcagcacgtgggcaatgtccaggactttctgcgcgtgctcttcggctttctctaccgcaagaccgacttctaccgcctgctgcgccatcctactgaccgcatgggcttcccgcccggggccgcacaggccctggtgttgcaggtctttaaaacatttgatcacatggcccgccaggatgatgagaaaaggaagaaggaactggaagagaaaatcagaaaaaaggaggaagaggccaaggcagtggcagctgccacagctgagaaggaagctgtgccagtcccagtgcaggaggtggagattgatgctaccacagcgttgagtggacctcgggaagtagaaaaggaggagctcccaggcccacagggccccgagcgcaaagtgacccatggctcggaggaggcagaagctccaggaacagctagcagtgctgctgaaggccctaaggaccctcctgtgctccccaggatccaggagcagttccagaaaaatcctgacagttacaatggtgccattcgtgagaactatacctggtcgcaagactacactgacctggaggtcagggtgccagtgcccaagcatgtggtgaaggggaagcaggtctctgtggcccttagcagtggctccatccgcgtggccatgttggaagaaaatggagagcgggtcctcatggaagggaagctcactcacaagatcaacaccgagagttccctctggagccttgagccgggcaagtgtgttttggtgccttcctggaaggaacgtcccacaacattcccgttggcccaaactcaatcacacgggcagctgcgaggagtaaagccatcctcactgggcacagtgcttccctgaatagaaatgaggttccgttactaaggaaggaaagggatataaatgctggtgagtcatcggcacagatcgggggatgctgaggtaagtttattcacactgagggtgaagtttttctgtgaggacattttgggagcactgttcagtcagtgacagtctggggtccctctgggaaattattatgttctgggaccaggcagataaaagaggacctggaaaatgaaagtgtatccaggaaatgatgaggtcacagtgaccttgtagagggcacctaattctgacccaatgaatggttcagagtgactttctaaaccactgagaaaagaggccaggaggcaggtgctcactttagcagtgcttatgccctgtcagtaagtagaaactggctgcaaggtcaggtgtcccaacctgtcgggaggtgggacctcataggaacctaagatcttgacatttggtatgttggtgacaatgtgggaagccctgggatgagagggaacatccttgcaggacgcctgcaggtggaccacagacacacctgggtacctcaggagacactagacacggtccttagcaaagtagagaggacgaccatggtcctgtgctgctggggggctgaggccaggctgctacttcagaggacttgcctagtcttagaaagtaactcagggtaaagggccggtacaatgttctttactctcaaatggttcataaacaaacattattatgttgtatgccaacacatagagtgcaagagctgctaaatgcctgtgtggctctctgtactttgagcaatgtgtaaatttgaagttatttgtaaataaatgagtggtattgcaagcatacaaggaaactcagcatcattaggggggaaaagtcaaaattacagtgagaggccttatatacctgtgagagtggctaagaagcccacagtgctcaatttgaaggagctgtggtaccctgaactcactgctgccgtgagcgccaggcggtgggcatagccagtgtgctcacattgcataacaacctactctatgctcccaagaggtggaaacacacagatcctcacgatagcttcctgcccaactgccaaaccttaggaacatctccatggccatggacagatagtgttcacctacgtcatggaatagtcttgccaagcgtcatagtccacaggatccagaaaggacgtgtgtgacaagctcacaagctgtgggtttcatggggaagacaccctggacctggacaagctggatggcaagatgagcaatgcagaatggagtggagggaggggcctggctgtgggtgggctgcagtggaggagatgaaactgcagcagggcgagttttgctgtgtgcaaactacacctccacaagtccaacttgttacagagtaacaaaatgttaaaacaaacacagctaatttaagcaagccatgggagtccttttgcctgggtgtggtctttagccaggaacccttgaggcctgttacatgaacattttttctttgttctcacacaactctgattctgtcttcagtatcaataacaccctaccccaccttctcagaactgagtgtattctaaccactttaagtagtttatttggaagattaaatgcccaaagtgtcttacctgggttccatagaagtatcactccaaggaagtcagtgatgcttagaacttgtcagctaacttgtcaacttctgggacatgaagctatttaaaaaataaaggataggtcctaggtgtgaggataaggagccagacagaacagcacatgaaatgctttgtggaaaaggaggccaggccagtgaagggtgaggagaatcacactagcactgcagccttacttaatctttgactgcccactcagagcattcacaaaatttttagaaataccgtcttggattttccaagcatctttggtgtggtctgctgccccagattcaagagcatcctggaccttaggagagaggtcactgaggaaaatactggcccgtgtatgcttgtatgtagccaggcaaaggaataacgattaagctgctgcatccctgaaaatagctataacaacaaccaaaaatcccaaatgtccacgagggagcagatggagcctttccttgtgcagcaccaggatgtccagctccaatggaaaacaatgaggtggattcttgaaacctgcagtagaggtgccaagtgagccagcagttccattcgtaggtaaatgccaaaggagccgaaagggggagaatggatggttaggttgtggtaagtttatcctgtggaatgctttcagcacggagaggaatgaagttctgctacaagccacagtacgatgtccttcagaaactctataataagtgaaataagtcaacacagcaatataaggtttcatttgtgtgacatctgatgagaccagtaattgtgccagaggtgtcggagaagatatttaagagactttattatggtaaaatgaagagcgactacaactggctgtaggcttctttctggagtgatgtttgagggtatagacatgacggctggttgcataccatcgtggatgtgccaaatgccattcgactgttcacctttggggaaaaaaagtgttatgtaatttcacaataaaaaaattgtttttaaaacaa

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