LOCUS       NM_001085406            1566 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus MPN domain containing (Mpnd), mRNA.
ACCESSION   NM_001085406 XM_001058890 XM_001059058
VERSION     NM_001085406.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 1566)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB768016.1 and BC101893.1.
            
            On or before Apr 29, 2007 this sequence version replaced
            XM_001059058.1, XM_001058890.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158552.1, SRR8487231.186093.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               CB768016.1         15-186
            173-1566            BC101893.1         1-1394
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..1566
                     /gene="Mpnd"
                     /note="MPN domain containing"
                     /db_xref="GeneID:681944"
                     /db_xref="RGD:1589335"
     exon            1..28
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..1485
                     /gene="Mpnd"
                     /codon_start=1
                     /product="MPN domain-containing protein"
                     /protein_id="NP_001078875.1"
                     /db_xref="GeneID:681944"
                     /db_xref="RGD:1589335"
                     /translation="

MAAPESLSSTATAEEAPEEDEDEAETEDPERGTGSGGRSGSLGGSGGSTAGPGLALGGALTRRAVTLRVLLKDELLEPGEGVLSIYYLGRKFIGDLKLDGRIVWQENGQVFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKAAWLRRHQLHMPVAAADESPTSEGEEEELLLEEEEEDVLAGVSSEYKGHRPPGKGSLEPEATPPGKRVDKVRVPVRYCMLGSRDSARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDPDTAATVEEEIHQVLFLRGLSLVGWYHSHPHSPAAPSLQDIDAQMEYQLRLQGSNNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDYGIPMDVEMAYVQDSFLTNDVLQEMMMLVEFYKGAPDLVKFQEAWSPEHTYLDKLKMSLASRTPKDQGMCHVLEQVCSVLKQGS"

     misc_feature    190..492
                     /gene="Mpnd"
                     /note="Restriction Enzyme Adenine Methylase Associated;
                     Region: RAMA; pfam18755"
                     /db_xref="CDD:465856"
     misc_feature    775..1329
                     /gene="Mpnd"
                     /note="Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase;
                     Region: MPN_2A_DUB; cd08067"
                     /db_xref="CDD:163698"
     misc_feature    order(853..855,1024..1026,1030..1032,1054..1056,
                     1063..1065)
                     /gene="Mpnd"
                     /note="MPN+ (JAMM) motif [active]"
                     /db_xref="CDD:163698"
     misc_feature    order(1024..1026,1030..1032,1063..1065)
                     /gene="Mpnd"
                     /note="Zinc-binding site [ion binding]; other site"
                     /db_xref="CDD:163698"
     exon            29..285
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            286..522
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            523..646
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            647..728
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            729..825
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            826..898
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            899..975
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1144
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1215
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1305
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1398
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..1546
                     /gene="Mpnd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctgtgcagggacacagcggccatggcagctcccgagtctctgtcctccacggccacggccgaggaggcgccggaggaggatgaggacgaggcggagaccgaggacccggagcgcgggacgggtagcggagggcgcagcggcagcctcggtggcagcggaggcagcacggcagggcctgggttggccctagggggcgcgctcacgaggcgcgcggtcacgctgcgggtgctgctcaaagacgagctgctggagcccggtgagggggtgctatccatctactacctgggcaggaagtttatcggggacctgaaactagatggcaggatcgtgtggcaggaaaatggacaagtcttcaactcgcccagcgcctgggccacacactgcaagaagcttgtcaacccagccaagaagtctggctgtggctgggcctctgtcaagtacaagggccagaagctggacaaatacaaggccgcttggctccgccgtcaccagctacatatgcccgtagctgctgctgatgagagtcccaccagtgaaggggaggaggaggaactgctgctggaggaggaggaggaggatgtgctggctggggtttcatcagaatacaaaggccacagacctcctgggaagggttccttggagccagaagccacacccccagggaaacgtgtggacaaggtccgggtgcccgtccgttactgcatgctgggcagcagagattctgccaggaacccccacactctggtagaagtaacatccttcgctgccatcaacaagttccagccattcaacgtggccgtttccagtaatgtgctgttcctcttggacttccactgtcacctgactcggagtgaggtcgtgggctaccttggtggtcgctgggacatcaataatcagatgctgaccgtgctgagagccttcccctgcaggagtcggctaggggaccctgatactgcagccacggttgaggaggagatccaccaggtcctgttcctgcgaggcctgtccctggtgggctggtaccacagccacccacacagccctgcagcaccctccttgcaggacatcgatgcacagatggagtaccagttgagactgcaaggctccaacaatggcttccagccctgcctggccctgctgtgctccccctactactccggcaacccaggccctgagtccaagatctgccctttctgggtgatgcctccccctgagcaaaggcccagtgactatggaatccccatggatgtagagatggcgtatgtccaagatagcttcctgaccaacgatgttcttcaggagatgatgatgctggtggagttctacaaaggtgcccctgaccttgtgaagttccaagaggcctggagcccagagcatacctacctggacaagctcaagatgtccttggccagcaggaccccgaaggaccagggcatgtgccacgtgctggagcaggtctgcagcgtgctcaagcaggggagctgaggctgtaagctttgctgtcctgggacaggctgggtaataaagtctctgagtgcctacagcaaaaaaaaaaaaaaaaaaaaa

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