LOCUS       NM_001034929            4904 bp    mRNA    linear   ROD 01-MAY-2025
DEFINITION  Rattus norvegicus solute carrier family 39, member 9 (Slc39a9),
            transcript variant 3, mRNA.
ACCESSION   NM_001034929 XM_234355
VERSION     NM_001034929.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4904)
  AUTHORS   Kabbesh,H., Bulldan,A., Konrad,L. and Scheiner-Bobis,G.
  TITLE     The Role of ZIP9 and Androgen Receptor in the Establishment of
            Tight Junctions between Adult Rat Sertoli Cells
  JOURNAL   Biology (Basel) 11 (5), 668 (2022)
   PUBMED   35625396
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4904)
  AUTHORS   Bulldan,A., Dietze,R., Shihan,M. and Scheiner-Bobis,G.
  TITLE     Non-classical testosterone signaling mediated through ZIP9
            stimulates claudin expression and tight junction formation in
            Sertoli cells
  JOURNAL   Cell Signal 28 (8), 1075-1085 (2016)
   PUBMED   27164415
  REMARK    GeneRIF: in Sertoli cells, testosterone acts through the receptor
            ZIP9 to trigger the non-classical signaling cascade, resulting in
            increased claudin expression and tight junction formation.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jan 12, 2022 this sequence version replaced NM_001034929.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105849.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-214               JAXUCZ010000006.1  106022858-106023071
            215-647             JAXUCZ010000006.1  106023201-106023633
            648-756             JAXUCZ010000006.1  106041636-106041744
            757-957             JAXUCZ010000006.1  106045341-106045541
            958-1026            JAXUCZ010000006.1  106052009-106052077
            1027-1112           JAXUCZ010000006.1  106054231-106054316
            1113-1247           JAXUCZ010000006.1  106055335-106055469
            1248-1349           JAXUCZ010000006.1  106057963-106058064
            1350-4904           JAXUCZ010000006.1  106058180-106061734
FEATURES             Location/Qualifiers
     source          1..4904
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..4904
                     /gene="Slc39a9"
                     /note="solute carrier family 39, member 9"
                     /db_xref="GeneID:314275"
                     /db_xref="RGD:1311236"
     exon            1..214
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            215..647
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    534..536
                     /gene="Slc39a9"
                     /note="upstream in-frame stop codon"
     CDS             552..1415
                     /gene="Slc39a9"
                     /note="isoform 2 is encoded by transcript variant 3; zinc
                     transporter ZIP9; ZIP-9; zrt- and Irt-like protein 9;
                     solute carrier family 39 (zinc transporter), member 9"
                     /codon_start=1
                     /product="zinc transporter ZIP9 isoform 2"
                     /protein_id="NP_001030101.1"
                     /db_xref="GeneID:314275"
                     /db_xref="RGD:1311236"
                     /translation="

MDDFLSISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYEEVLEGKHHQASEAKQNVIASDKAAEISVVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGSSHVHSTDDPESARPSSSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPAMSMLTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEDTSTNQSGSSLSPRPLPSGKN"

     misc_feature    561..623
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    576..1385
                     /gene="Slc39a9"
                     /note="ZIP Zinc transporter; Region: Zip; pfam02535"
                     /db_xref="CDD:396884"
     misc_feature    636..638
                     /gene="Slc39a9"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q3KR82.1); glycosylation site"
     misc_feature    654..716
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    870..932
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    990..1052
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    1080..1142
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    1182..1244
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    1275..1277
                     /gene="Slc39a9"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q3KR82.1); glycosylation site"
     misc_feature    1284..1346
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     transmembrane region"
     misc_feature    1353..1412
                     /gene="Slc39a9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3KR82.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1362..1364
                     /gene="Slc39a9"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q3KR82.1); glycosylation site"
     exon            648..756
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            757..957
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1026
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1112
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1247
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1349
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..4904
                     /gene="Slc39a9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gagacaatccggaagtgggagtaatgaagaggtgccacttggcggccatggcagctgtagtattggcggctcagggtcagggcctggctgagggaagtaccatgggtagcaccgggtgtaggacagagacagcgtcgtatcgactttgctgttgaatcctccagcccattgttagagacttgcaggacatcttgcccgactctagactcgaaagggacgttgtcttggggagcgggtcgtcgtgtcaccctcattctgacgattaaggagatctctttttgcacaatttctccatctgttacctaccggaatcccagtgactggcaaccaagtacctaagactgcgcaaagttttctctggtgctagtatcagcaaaaggagcttgcttcttaagagagcggcgggcttcatgaactcaccggccggtggcaaggctgaaagaagtgaggaaattcccgttttcttggaagaccacacgtttaaacagcccaagcgccgtttgaaactggaattttaaagcctggtggaggggtgactacaggagggcagaatggatgactttctctccattagtctgctgtctttggcaatgttggtgggatgttacgtggctggaatcattcctttggctgttaatttctcagaggaacggctgaagctggtgactgtgttgggtgctggccttctctgtggaactgcactggcagtcatcgtgccggaaggggtgcatgcactttatgaggaggtcctggagggaaaacaccaccaagccagtgaagcgaagcagaatgtgattgcatcagacaaagcagcagaaatatcagttgtccatgagcatgagcacagccacgaccacacacagctgcatgcctacattggtgtgtccctggtactgggcttcgttttcatgttgctcgtggaccagattggcagctcccatgtgcattccactgacgatccagaatcagcaaggcccagcagttccaaaatcaccaccacactggggctggttgtccatgctgcagctgatggtgtagctttgggagcagcagcctctacttcacagaccagtgtccagttaattgtgttcgtggcaataatgctacataaggctccagcagcatttgggctggtttccttcctgatgcatgctggcctggagcggaatcgaatcagaaagcacttgctggtctttgcactggcagcaccagccatgtccatgctgacgtacttaggattaagtaagagcagtaaagaagccctttcagaggtcaatgccactggagtggccatgcttttctctgccgggacatttctttacgttgccaccgtccatgtcctccctgaggacaccagcactaaccagtcaggttccagcctcagtccacggccattgccatcggggaagaactagcgtgtgacgctcctcacttcctcagtgtcttgtctcaccttgcccatctccacccctgttcctagagtccaagggagatgagagtcaatcgtggaaagtgggacagcatatagcaggaacatcagaattagacagactttgtgttgtcttttaaagggactttgatgtattgagttttgatgtttctcttaaccctattctcagggaagatggaatttagttttaaagaaaagtggagaacttcatacaatgaaatagtaattatgaaacttcagtgttctgtaattaagctaaagttttttcccttagtatagaggctctgccactttacccattggttttaacatggttctcaccatgtaagactggtgctttagcatctgtgccacagccttgagagaaggcgggaacacccatcccttagatgctaaagatgatggcaactaatttgaggttagaataaggaaaataagagcaggagaaaaaagctgaactgaacccaaaagaaacatccactgaaaggggtgtctagagtcatcaacagctcctttgcacgtgcctccctaaatagagcctgcccttccttccagtagagcaatggaggtgggactggcttttgaagaggggtctgttatcatatagcatttttttaaaaagtatcttttgcagaatacttgtctgtagcacactcttagtagccagattctgttcaggcacaggatttctgtcaagaacagtctgatcacagtgaaattaagggatgttaaattttccaggaatttggatagttactgatatcttgtagtaacctttttaaaaagtaacactattacaaagtatgttgtccttttcttccagtcagtggttctcaaccctctgaacactgcaatcctttaatacagttcctcatgttgtggtgccctcccaaccataaaattattttgttgctacttcataactgtaattttactactgttatgatctgtaatgtaaatgtctgatacaggctatctgatatgccacctttgtgggcatcgagacttacaggttgagaagcgctgttctaagtatttcttttagcagcctctgtccctctggctgagcccttgcccagagtggagagtgtttctgtccactccgtagctcttgagcagaaggcggtggggctgtatcagaagggagtatctgctgctggcctcagtctccttgaaatcatgtctgcatcccactcttcccgtgctcttcccctccccagcctacccccactgtgtactactactgctggtgatgtcagtccttgtgtgaggtgaattctcaccacttctttaaccatgaagacagcactgtttcttcttcatttccttcacctaagttacctttgtgcccaatacaacttttttacaccctcaaaaatgtcacctcctcatgagagttgacacagtcactagtactctgataatttaagaaattgagacagcaaaagtattcaacaaaggtaattcttccatgtttgccaaaatctgaataaatcctagtcagataaatgtataatactgtattaatttacattttctgtaccatttcagaaacactttacataaacagggagccaaggctagttttttcagagcagtgagtgcagtcattgtgttttctgtgacatctgtgccagcatgcctgtagattttctctcctgaattgtcactaggtcagccggcagctgtggggttaaacttgtgcgccctctgctggctgtagtggagaaagcagcagaaatgagacgcagctctgtgtggaggctggtacccattgcatcccgagctaaagtgttaatgtgtgcagtgtgggagttgggggtgactctcgtaataggtgactaggaaaggtttgggctcatctagtccttccaaagtacagatgtcttgatctctctagaggctcactttgtcggggtggtccgggtagaagcagcttctgtcaccttgctccgtgcagtggtcagacacttgttgtgctggccagagcctcttgttcagcagtgccttgccaactcactcgaagttgggctagaatatcatgttgggtagggccttggactctggcaaggagtgaaccatcaaacgtccaaatctgccttcctctctgggcctcagtagtagtgagctttccatgcctggagctgctgcctggggactgagtcccttccctgctctgcaggctcagatagccatatgactcttaatagggctcagatgcaggagaggcagcaggaaccagcagagcctccatctagtgggggagaggtcgctcatgcagcaggcagtgccccgaaagcagccaccttgatcgcttcacaacacgtttcagttctgttttcttcctcctaactccctctggaggtgtggatgccttaatgtgcaaacacacttgaacacattggtgatacttgagctgctgccacgattacaagtggaattatgggctaccaaagaagcaattgatgaaaaagcatgggctatccttcctcatgaccaaagcaatcttatttgggattagagttcctttcccccagaatctagatgcatcccccctccccagttcccagtgttgtcagtctccgagtcagcagggcagtgatgtccgtttgattccgctttcctgtgtgtgctattgccagcttggttcttacaggcagactttctggcctgaaaatgccaacggttggaatggcactacccactgagccaagtcaacctgttctggggatctgggtcattagaagaaagggagggtctgttcttttagaaaggggaaaatagatttgtttaaatcagtctgtcaccactggctggttttatttttcaagaattagagctaggaggaacatagcagtgacagagcgtgttaagccttgaccctcatgctagtgaggttctgaacatgggactgtatgtcaatagcacaagcctctaaaacacccttaccttttgggccagagccccagactactggggctcacacagtcatcgggcaagagtcctggaggcagacttgtgttcagtgcagagtgggacgcacccctgaagagcactggctgagatactacacaactcagcctttttaactcgagacatcgaagttcagctcgggagagctgagggtgggggctggtgggaaaggactggcagacagtaggacttccttacatgtgctcagccctcacagagccaagcacagagactggctttgctctgtctgccgtgtcttcccgaaaactgggactctaatggtaacaccatgattcccctggtttggtggcctaaacggtgattttaaatgtctccttttctggattctttgtatacataaactcattccatggatggctgccttataattttgtgtctttccactttaattgtgaatggtttaaaaattgctgtttccgatttgttttatgatattaaatttttattagtgcatacctta

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