LOCUS       NM_001081671            1120 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus claudin 34B2 (Cldn34b2), transcript variant 1, mRNA.
ACCESSION   NM_001081671 XM_621123 XM_911023
VERSION     NM_001081671.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1120)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1120)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC100353.1 and AK006680.1.
            
            On Feb 27, 2018 this sequence version replaced NM_001081671.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100353.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849374,
                                           SAMN00849385 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1056              BC100353.1         1-1056
            1057-1120           AK006680.1         1014-1077
FEATURES             Location/Qualifiers
     source          1..1120
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 72.38 cM"
     gene            1..1120
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /note="claudin 34B2"
                     /db_xref="GeneID:73347"
                     /db_xref="MGI:MGI:1920597"
     exon            1..50
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            51..181
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    111..113
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /note="upstream in-frame stop codon"
     exon            182..1120
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..836
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /codon_start=1
                     /product="claudin 34B2"
                     /protein_id="NP_001075140.1"
                     /db_xref="CCDS:CCDS53232.1"
                     /db_xref="GeneID:73347"
                     /db_xref="MGI:MGI:1920597"
                     /translation="

MPLKKCHGQMGGFALTTVAWLLCCISTGLPQWQVWHYEDPVVLKPTVALVGMWRACVFHTDRNSSNTRVCYQYNYDGSIPLYIRGNQHLLLVSSFLGLFGKITTIIALSNVHMGRVRRNATCNPFRLSGILNIIASSFLYLAVLFNYIAIMSKWGIAFPPSFNLPFQPDTRKMGSAMALAIIAAVFFLLSGTICLSSNLNIDKTPRSKM"

     misc_feature    258..794
                     /gene="Cldn34b2"
                     /gene_synonym="1700042B14Rik"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
ORIGIN      

gtcctgtgttctataagaaagcaagctgagcaaggaggggaagcaagccaaatcctgcataatgctttccatagtgactgtagctgtgtgtagtcctatgcaagagtgaatgagaaccaccccccccaactacttcagcatcttttgtctgttgttttactgatctttcattctcaccaagttctcaagtattcactgccatcatcatgccgttgaaaaagtgccatggccaaatgggaggttttgctttgaccactgtggcctggctactctgctgcatatccacaggcctccctcagtggcaagtgtggcactatgaagatcctgtggtcctcaagcctacagtggctttagtgggcatgtggagagcctgcgttttccacaccgacagaaactccagcaacaccagagtatgttaccaatacaactacgatggctccattcctttgtatattcgaggaaaccagcacttgctgctggtttctagctttcttgggctttttgggaaaatcactaccattattgctctttcgaatgtgcatatgggaagagtacggaggaatgccacctgcaatcctttcagactttcaggcatactgaacatcattgctagcagctttctttaccttgctgttttgttcaattacatagccatcatgagcaaatgggggattgccttcccaccatctttcaatttgcctttccagccagacactcggaagatgggaagtgccatggctttggcaattatagctgcagttttctttctactaagtggcacaatttgcctttcttcaaatttaaacatagacaagacgccccgttccaaaatgtaaatcgatacgttacatagccttgaaatgccagcaaagataatgagtattctttacatgtctacacaaattttcaaagaacttgaaaggatgccgattgtggcctgcgggaaaaaaataatccagttgactttctcttatctttttttggcttcttttgtgtttccttaatgcattatttggattgtgggcttttattaaataaaatattattttatgggtagtattgatttgtgttctacttgctgtcaaaaatagcatacaatcaataaacctaatccatattc

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