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2024-11-23 01:36:02, GGRNA : RefSeq release 226 (Sep, 2024)
Summary:
Results:
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misc_feature 191..553 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(347..349,392..394,434..436,446..448,500..502, 521..523,527..529) /gene="AGO4" /gene_synonym="EIF2C4" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 100..441 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(235..237,280..282,322..324,334..336,388..390, 409..411,415..417) /gene="AGO3" /gene_synonym="EIF2C3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 1055..1396 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1190..1192,1235..1237,1277..1279,1289..1291, 1343..1345,1364..1366,1370..1372) /gene="AGO3" /gene_synonym="EIF2C3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
misc_feature 1050..1391 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1185..1187,1230..1232,1272..1274,1284..1286, 1338..1340,1359..1361,1365..1367) /gene="AGO3" /gene_synonym="EIF2C3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
misc_feature 175..327 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 328..690 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order...
misc_feature 97..351 /gene="AGO4" /gene_synonym="EIF2C4" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 382..534 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 535..897 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 280..534 /gene="AGO4" /gene_synonym="EIF2C4" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 565..717 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 718..1080 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 1444..1728 /gene="AGO3" /gene_synonym="EIF2C3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 1756..1908 /gene="AGO3" /gene_synonym="EIF2C3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1909..2271 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut,...
misc_feature 509..793 /gene="AGO3" /gene_synonym="EIF2C3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 821..973 /gene="AGO3" /gene_synonym="EIF2C3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 974..1336 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 675..959 /gene="AGO3" /gene_synonym="EIF2C3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 987..1139 /gene="AGO3" /gene_synonym="EIF2C3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1140..1502 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 373..597 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 625..777 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 778..1140 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
feature 5833..6057 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 6085..6237 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 6238..6600 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
feature 8028..8252 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 8280..8432 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 8433..8795 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
misc_feature 519..743 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 771..923 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 924..1286 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
misc_feature 313..705 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 733..885 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 886..1248 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key...
LOCUS XM_054334825 19923 bp mRNA linear PRI 26-AUG-2024 DEFINITION PREDICTED: Homo sapiens argonaute RISC catalytic component 3 (AGO3), transcript variant X7, mRNA. ACCESSION XM_054334825 VERSION XM_054334825.1 DBLINK BioProject: PRJNA807723 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo...misc_feature <1410..1682 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain; Region: PAZ; pfam02170" /db_xref="CDD:460472" misc_feature 1761..3038 /gene="AGO3" /gene_synonym="EIF2C3" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing...
misc_feature 1524..1667 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1668..2021 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; Region: PAZ_piwi_like; cd02845" /db_xref="CDD:239211" misc_feature order...
misc_feature 1142..1285 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1286..1639 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; Region: PAZ_piwi_like; cd02845" /db_xref="CDD:239211" misc_feature order...
misc_feature 1524..1667 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1668..2021 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; Region: PAZ_piwi_like; cd02845" /db_xref="CDD:239211" misc_feature order...
misc_feature 477..866 /gene="AGO4" /gene_synonym="EIF2C4" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 897..1049 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1050..1412 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 97..351 /gene="AGO4" /gene_synonym="EIF2C4" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 382..534 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 535..897 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 175..327 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 328..690 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order...
misc_feature 280..534 /gene="AGO4" /gene_synonym="EIF2C4" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 565..717 /gene="AGO4" /gene_synonym="EIF2C4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 718..1080 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 191..553 /gene="AGO4" /gene_synonym="EIF2C4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(347..349,392..394,434..436,446..448,500..502, 521..523,527..529) /gene="AGO4" /gene_synonym="EIF2C4" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
D. TITLE Molecular dissection of human Argonaute proteins by DNA shuffling JOURNAL Nat Struct Mol Biol 20 (7), 818-826 (2013) PUBMED 23748378 REMARK GeneRIF: Chimeras with Ago4 N-terminal domains were defective in RISC activation & sometimes also in RNA loading. This highlights the pleiotropic role of the Ago N domain & emphasizes the unique position of human Ago4 within the Ago protein family. REFERENCE 5 (bases 1 to 5087) AUTHORS Gu S, Jin L, Huang Y, Zhang F and Kay MA. TITLE Slicing-independent RISC activation requires the argonaute PAZ domain JOURNAL Curr Biol 22 (16), 1536-1542 (2012)...
misc_feature 401..625 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 653..805 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 806..1168 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
BX104163.1 and AA251146.1. On Nov 23, 2018 this sequence version replaced NM_024852.3. Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene....
AA251146.1 and AL138787.11. On May 31, 2019 this sequence version replaced NM_177422.2. Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene....
derived from DB091271.1, BC031060.1 and AB079366.1. On Nov 22, 2018 this sequence version replaced NM_152431.2. Summary: PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857])....; Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" misc_feature 959..1309 /gene="PIWIL4" /gene_synonym="HIWI2; MIWI2" /note="PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the...
misc_feature 313..705 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 733..885 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 886..1248 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key...
misc_feature 496..780 /gene="AGO3" /gene_synonym="EIF2C3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 808..960 /gene="AGO3" /gene_synonym="EIF2C3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 961..1323 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
misc_feature 512..796 /gene="AGO3" /gene_synonym="EIF2C3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 824..976 /gene="AGO3" /gene_synonym="EIF2C3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 977..1339 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and...
LOCUS NM_001164623 14493 bp mRNA linear PRI 12-AUG-2024 DEFINITION Homo sapiens argonaute RISC catalytic component 2 (AGO2), transcript variant 2, mRNA. ACCESSION NM_001164623 VERSION NM_001164623.3 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata;...version replaced NM_001164623.2. Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-...
misc_feature 373..597 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 625..777 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 778..1140 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
misc_feature 386..610 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 638..790 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 791..1153 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key...
misc_feature 313..705 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 733..885 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 886..1248 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key...
misc_feature 313..705 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 733..885 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 886..1248 /gene="AGO1" /gene_synonym="EIF2C; EIF2C1; GERP95; hAgo1; NEDLBAS; Q99" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key...
misc_feature 519..743 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 771..923 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 924..1286 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
misc_feature 585..809 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 837..989 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 990..1352 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
misc_feature 100..441 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(235..237,280..282,322..324,334..336,388..390, 409..411,415..417) /gene="AGO3" /gene_synonym="EIF2C3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 1650..1934 /gene="AGO3" /gene_synonym="EIF2C3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 1962..2114 /gene="AGO3" /gene_synonym="EIF2C3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 2115..2477 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut,...
Hominidae; Homo. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK302409.1, AP000359.1 and AP000358.1. Summary: This gene encodes a member of the PIWI subfamily of Argonaute family proteins. This subfamily of proteins contains a PAZ domain, found in proteins involved in RNA-mediated gene silencing, and a C-terminal Piwi domain. The encoded protein is thought to function in maintenance of germline cells. Multiple transcript variants encoding different isoforms have been found for this gene....
REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000359.1 and AB079368.1. On Dec 20, 2011 this sequence version replaced NM_001008496.2. Summary: This gene encodes a member of the PIWI subfamily of Argonaute family proteins. This subfamily of proteins contains a PAZ domain, found in proteins involved in RNA-mediated gene silencing, and a C-terminal Piwi domain. The encoded protein is thought to function in maintenance of germline cells. Multiple transcript variants encoding different isoforms have been found for this gene....
misc_feature 1050..1391 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1185..1187,1230..1232,1272..1274,1284..1286, 1338..1340,1359..1361,1365..1367) /gene="AGO3" /gene_synonym="EIF2C3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
misc_feature 1055..1396 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1190..1192,1235..1237,1277..1279,1289..1291, 1343..1345,1364..1366,1370..1372) /gene="AGO3" /gene_synonym="EIF2C3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
feature 2965..3189 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 3217..3369 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 3370..3732 /gene="AGO2" /gene_synonym="CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a...
LOCUS XM_005270576 19922 bp mRNA linear PRI 25-AUG-2024 DEFINITION PREDICTED: Homo sapiens argonaute RISC catalytic component 3 (AGO3), transcript variant X7, mRNA. ACCESSION XM_005270576 VERSION XM_005270576.5 DBLINK BioProject: PRJNA168 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo...misc_feature <1410..1682 /gene="AGO3" /gene_synonym="EIF2C3" /note="PAZ domain; Region: PAZ; pfam02170" /db_xref="CDD:460472" misc_feature 1761..3038 /gene="AGO3" /gene_synonym="EIF2C3" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing...
misc_feature 1144..1287 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1288..1641 /gene="PIWIL2" /gene_synonym="CT80; HILI; mili; PIWIL1L" /note="PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; Region: PAZ_piwi_like; cd02845" /db_xref="CDD:239211" misc_feature order...
REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000359.1 and AP000358.1. On Aug 14, 2020 this sequence version replaced NR_045649.1. Summary: This gene encodes a member of the PIWI subfamily of Argonaute family proteins. This subfamily of proteins contains a PAZ domain, found in proteins involved in RNA-mediated gene silencing, and a C-terminal Piwi domain. The encoded protein is thought to function in maintenance of germline cells. Multiple transcript variants encoding different isoforms have been found for this gene....
record has undergone validation or preliminary review. The reference sequence was derived from AP000359.1, BC144696.1 and AP000358.1. On Aug 31, 2013 this sequence version replaced XM_005261612.1. Summary: This gene encodes a member of the PIWI subfamily of Argonaute family proteins. This subfamily of proteins contains a PAZ domain, found in proteins involved in RNA-mediated gene silencing, and a C-terminal Piwi domain. The encoded protein is thought to function in maintenance of germline cells. Multiple transcript variants encoding different isoforms have been found for this gene....
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Redirect URI : http://ggrna.dbcls.jp/ja/hs/Argonaute+%22PAZ+domain%22
lang : ja |
div : |
spe : hs |
query_string : Argonaute "PAZ domain" |
format : html |
download :
0.000 | 0.000 | search_start;
0.080 | 0.080 | count_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:Argonaute)%7C(nt:Argonaute)%7C(aa:Argonaute))?source=Homo sapiens (human)?to=0&format=json
0.088 | 0.008 | count_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:PAZ+domain)%7C(nt:PAZ+domain)%7C(aa:PAZ+domain))?source=Homo sapiens (human)?to=0&format=json
1.255 | 1.167 | search_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:Argonaute)%7C(nt:Argonaute)%7C(aa:Argonaute))%26((full_search:*:PAZ+domain)%7C(nt:PAZ+domain)%7C(aa:PAZ+domain))?source=Homo sapiens (human)?to=49?from=0?snippet=full_search?drilldown=source?get=accession,version,gi,length,symbol,synonym,geneid,division,source,definition&format=json
1.265 | 0.010 | cgi_end;
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GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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