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Previous release (v1)
2025-09-13 21:16:10, GGRNA.v2 : RefSeq release 231 (Jul, 2025)
LOCUS NM_001313687 6107 bp mRNA linear VRT 25-JUN-2025
DEFINITION Danio rerio nucleoporin 205 (nup205), mRNA.
ACCESSION NM_001313687 XM_009293478
VERSION NM_001313687.2
KEYWORDS RefSeq.
SOURCE Danio rerio (zebrafish)
ORGANISM Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE 1 (bases 1 to 6107)
AUTHORS Amsterdam,A., Nissen,R.M., Sun,Z., Swindell,E.C., Farrington,S. and
Hopkins,N.
TITLE Identification of 315 genes essential for early zebrafish
development
JOURNAL Proc Natl Acad Sci U S A 101 (35), 12792-12797 (2004)
PUBMED 15256591
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
JBMGRA010000018.1.
On Jun 25, 2025 this sequence version replaced NM_001313687.1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data because no single transcript from the same
strain was available for the full length of the gene. The extent of
this transcript is supported by transcript alignments and
orthologous data.
##Evidence-Data-START##
Transcript exon combination :: GFIL01028944.1,
SRR32588732.28123442.1 [ECO:0000332]
RNAseq introns :: mixed sample support SAMEA3505370,
SAMEA3505371 [ECO:0006172]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-46 JBMGRA010000018.1 13630399-13630444 c
47-189 JBMGRA010000018.1 13627598-13627740 c
190-361 JBMGRA010000018.1 13625217-13625388 c
362-506 JBMGRA010000018.1 13624962-13625106 c
507-666 JBMGRA010000018.1 13623799-13623958 c
667-895 JBMGRA010000018.1 13623492-13623720 c
896-1060 JBMGRA010000018.1 13622642-13622806 c
1061-1236 JBMGRA010000018.1 13622389-13622564 c
1237-1353 JBMGRA010000018.1 13621082-13621198 c
1354-1491 JBMGRA010000018.1 13620796-13620933 c
1492-1642 JBMGRA010000018.1 13618345-13618495 c
1643-1851 JBMGRA010000018.1 13618033-13618241 c
1852-2034 JBMGRA010000018.1 13617450-13617632 c
2035-2085 JBMGRA010000018.1 13617242-13617292 c
2086-2295 JBMGRA010000018.1 13615962-13616171 c
2296-2533 JBMGRA010000018.1 13615348-13615585 c
2534-2723 JBMGRA010000018.1 13612376-13612565 c
2724-2844 JBMGRA010000018.1 13612180-13612300 c
2845-2923 JBMGRA010000018.1 13612022-13612100 c
2924-3088 JBMGRA010000018.1 13611776-13611940 c
3089-3213 JBMGRA010000018.1 13611450-13611574 c
3214-3328 JBMGRA010000018.1 13610440-13610554 c
3329-3478 JBMGRA010000018.1 13608888-13609037 c
3479-3553 JBMGRA010000018.1 13608729-13608803 c
3554-3711 JBMGRA010000018.1 13607748-13607905 c
3712-3792 JBMGRA010000018.1 13606615-13606695 c
3793-3984 JBMGRA010000018.1 13606333-13606524 c
3985-4189 JBMGRA010000018.1 13605527-13605731 c
4190-4288 JBMGRA010000018.1 13605320-13605418 c
4289-4434 JBMGRA010000018.1 13604273-13604418 c
4435-4748 JBMGRA010000018.1 13603869-13604182 c
4749-4887 JBMGRA010000018.1 13603419-13603557 c
4888-5014 JBMGRA010000018.1 13601539-13601665 c
5015-5088 JBMGRA010000018.1 13601393-13601466 c
5089-5220 JBMGRA010000018.1 13601083-13601214 c
5221-5326 JBMGRA010000018.1 13599736-13599841 c
5327-5484 JBMGRA010000018.1 13599489-13599646 c
5485-5614 JBMGRA010000018.1 13599212-13599341 c
5615-5719 JBMGRA010000018.1 13598971-13599075 c
5720-5778 JBMGRA010000018.1 13598831-13598889 c
5779-6107 JBMGRA010000018.1 13596955-13597283 c
FEATURES Location/Qualifiers
source 1..6107
/organism="Danio rerio"
/mol_type="mRNA"
/strain="Tuebingen"
/db_xref="taxon:7955"
/chromosome="18"
/map="18"
gene 1..6107
/gene="nup205"
/gene_synonym="zgc:111802"
/note="nucleoporin 205"
/db_xref="GeneID:445382"
/db_xref="ZFIN:ZDB-GENE-040715-8"
exon 1..46
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
CDS 19..5931
/gene="nup205"
/gene_synonym="zgc:111802"
/note="nucleoporin 205kDa"
/codon_start=1
/product="nuclear pore complex protein Nup205"
/protein_id="NP_001300616.2"
/db_xref="GeneID:445382"
/db_xref="ZFIN:ZDB-GENE-040715-8"
/translation="
MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLISDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAAVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRDPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS"
exon 47..189
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 190..361
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 362..506
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 507..666
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 667..895
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 896..1060
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 1061..1236
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 1237..1353
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 1354..1491
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 1492..1642
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 1643..1851
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 1852..2034
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2035..2085
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2086..2295
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2296..2533
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2534..2723
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2724..2844
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2845..2923
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 2924..3088
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3089..3213
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3214..3328
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3329..3478
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3479..3553
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3554..3711
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3712..3792
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3793..3984
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 3985..4189
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 4190..4288
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 4289..4434
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 4435..4748
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 4749..4887
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 4888..5014
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5015..5088
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5089..5220
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5221..5326
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5327..5484
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5485..5614
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5615..5719
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5720..5778
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
exon 5779..6107
/gene="nup205"
/gene_synonym="zgc:111802"
/inference="alignment:Splign:2.1.0"
ORIGIN
cccactcacgcttcagacatggcgacgcagatggcggtaaattcaggagccagtctgtgggggccgctgaaggagctctgggaggctgtggaaggggccatttggagacgtcaaccagaaagtgttcatcttttagatctgcagttgaagaaacacaaaccctacttcctcaacctctttaaaaacccaccgaagagtgcagaacagagagagaaggttcggaaagccagtacagaaggcattgctatccagggtcagcagggagcaagactacttcctgagcagctcatctctgaagccttcatccttagtgacctttttgaccttggagaactagccgccctcgagctgctgctggcaggagagcatcagcaacctcatttccccggcctgacccgaggcctggtagctgtgctcctttactgggatggtaaacgctgcgtggccaactctctccgctcacttatccagtccagacatgggaagactttcactcttgacttgagtcctgaattggtaaatctcaccacacggttcacagatgagctgatggcccagggtttgaccaagcaaatactgaacctgatctctgacgtcagcgtgacccgtgagtttgagaggctgcagaaagagcgtggccttggcaatgagaaacacaggaaagaggtatctgacctcatcaaagagtgccgacagtctctggcagagtgtttgtttgcgtgggcatgccagtcaccgctaggcaaagatgacacgctggctctcattgggcatttggagatggtgaccgctgaagctgacggctctttggatagtgtcaaccttgctttggtcatggcattgctctattccctggatgttagttttctggagcaaggaacagaagatagagaagacctgctccaggctttgcctctgttgacggagaaacagtacgtggcagcagtgcacagtcggctggtagagggtcaaggctggaagcttccaggactgcaggcagcggtgcagctggcctgggcgctgtctctgagggccctttcacaacttccacagggtgcagctttagtggagttcactgaagcagatgaggctctggcagaccaggcgctgttgggaggcgtcttcctctttctgacggagggcgtcctgggaagtgatggtttcagccaagaagaattttacacccggcggctgcattctctgattactgatttcctggcactcatgccaatgaaggtgaaacagttgcgcaaccgtgccgatgaagatgctcgtctgatccacatggctctgcagatgggcagcgagccgccatcatctcttcgcaaggacctggaccacctcatgatccttattggagaattttacagcaaagatccatttgaacttgagctggctttagagttttggtgtccatcagagtctcttcagcacacttcactcactggatcttttcttggagtacctctccaaagacccccacataaacaggtggttctctccaagtttgtgcgtcagatgggtgatctgcttcctgcgactctttacatcccatacctgcgaatgctgaaaggacttgcaaatggccctcagtgctcccactactgcttcagtttgcttaaaactaacggcgctccacacggagagaaccggcaggctggagtgtcaggcagtcttgtgtcatgggaacactttttccactctctcatgctgtaccatgaaaacctgcgacgagacgtgcccagtgccgacagcacacaataccgtcatctaccaatcagaggcatcactcagagagagctggaaggtctcactgcattcctccagctgctcaccacgatcatcacctggagtgagaatgcacgtctggctctttgtgagcaccctcagtggacgcctgtggtggtgatgctgggtttgctgcagtgtagtgttcagcccgtcctcaaagctcaagtccttcatgttctcgctgcttttggcaaatctcccgagattgcagcctccctctggcagtctctggagtacacacagatcctacaaacagtgaaaatccctggtcagagacaggctgctgggatcgaggtggagctgaatgagattgaatcgagctgtgaggagtatccactcacacgggccttttgtcatctgatcagtactctggtggagagcgcacttccagtcaatcttggagcaggactgcgagctcccggctttcaaccttatcttgacttcctgcgtgactctgtgtttctggccttccccacgcgagcctaccgtcgctcagcagaaaagtgggaggtagctgaagcagtgctagaggtttttcacaaacttctgcgagaatatgagccccagccttcagacttcctgccggagatggtggaacttcaaggagagcaggtgccggcccataagcccccggggcacagcctgatgttccaccttttgaacgactcacccaccctctctctctgcctcaacctactggaggagggcgcccgccagcttgacacatacgctcaattccctggcaagaagcagttagaatctgcagttctgcactgtctgtgtttgctggagctagccctgcagaaggaggtgacgttcatggatctgctgagagaaagtcaaacatcacttcttgtgtctcctttggagcagctcctgcagggcgtcagtgctcagagcagaaaggcagatcacatcaccaacattgctaggtacctgtatcacagcagctccaatcctgatgctgcgttccagagtgcaaagatcctgcgacgtatcactcgctacccaaacatccaggccagactggttggagacttcactcatgatcaggcagtgagtgagaggttgatggccggctttgtggagtgtctggacagtgaagaggctcaggaaggagtgaccacaaatgactcagactctgagaaacgggtggccagaattcgtcatgagaccaagatccacatcttgaatcttttgatcacgtccctggagctaacaggccccaatctgggcctgtatctgctgggctatgaagtcaagaagccagtttcctccactaaccttcaagacccaggtgttcttggctgtccgcggagctgcctgcatgcgattctcagtctgcttcagaggggcagtgactctcgctctggacctgggctcattaaacaggctcctcaactagctgaactctgctaccaggtgatttatcagctgtgcgcatgtcctgacacctctggcccaaccatgagatacctcaggaccagtcaggacttcctgttctctcatctgcaacacctacctttcgttttatcagaaaatgagatcgcggctctgtctcagatgtcctggctaatgaaaaccacagcaatcgagctccgagtgacctcactgaaccgccagcgctcacacacacagagactcctgaacctcctcctcgatgaccagccacacacattacacacagcagatggagagaccggcatggaggaggagaacagatcagtcagtggtttcctgcagtttggcaccgtctccaaggtgcgcaggaggctgctcagtgttttggatgccatagatttcagtcaggaggcaccagagcttttgcagctggacttctttgagcgcactcagatcgagcaggtcatcactaactgtgaacatgtcaacgagcagggacacaccgtctgcaatgtcaagttgctgcatcgagttttagttgcagagatcaatgcactacagggcatggcagccatcgggcaaagaccactgctaatggaggaggtgaattcagtcctgcagcaggtggtggaaaggaatcgcgtgcggcgcagtctcagtgccaagcgccatgctctgcagagctggaggagtctggtggagaccatcctcaccgcctgtccttcagaactcatccctgcagaccagcggcagctcatcatcagagatctgctgctcgacctgcatgacaaggtgttatcagaagatgctgctggtgaactgatgccaatcgtagccggagcagtcttcacattgacagcacacctcagccaatcagtgctgtccgaacagcagggggtggggccagagggtggctctggatcaggatttgcatccattgctaactccgcccttcacctcatcctgaggaagctgctggactttatcttgtgcacaggtggaggctttcagcgtctcagggctcatttgtatggagctctgctgtactacctgcagatcgcccagaaacctgaggagccagagacactgcagactggcacatccatgtgggagcgtttgactgcccctgaagattgcttctccaagctacagagagaaaacctgtccatcatcgagagctacggcactgcgctaatggaagtggtgtgcagagacgcttgtgatggccatgagatcggccgaatgctggctctggctgtgttagacagggtgttgtctatagacaggcagtgtcagtggctggtgtacttgtgtaacagtggttacctgcgtgtgctggtggagagtttaaagcaggatgacgtttctttgcaaactcttctcacgcctcagccgccgctgcttaaaccgttgtacatctacgagtccaaaatggctctgctgacccgcgtggccaagaccgctcagggtgcgatggagctgctgcgctgtggtctggtcgctcagctggtggagtgtcaggtgtttcacatgctccctcagaatgacgcactcagagtgtttgggcagagagatccttcagggtttattcctagtcctctggagcgatacaggcagatcctgcttcctacactcagactgatgcaggtcatcttgacctccaccaccgcacagcaccagcagggggcagcacaggtgctgcagtggcttatcgttcattcggatgtcattcagtctattctgcatggtcaggacatgagcatgggctctttacaggaactgtctctgctcactgccatcatcagcaagacggcactgccaggagcacttgagatgggacaggaaatcaacagcgctgccctcatggagttacagggacacatcggcagattccagcggcagtcgttgtctctgctggtgcgtctggtgggcactgatcgcgctcgctaccttaagcagattgaggacaccgtttctcccagcaacctagcagaaaaaagagaggaaatggaggttgccatgcaacagatctgtgctaatattatggagtactgccagacgctgctgctgcagagctcatctgaagcccagttctcactctgtctgttcagcccatcagcaagtgaaccagccgatgtgtccatcccctctgcccgcgtgcccagtctggggctggttctgctcctgctgaaaaacagcgccagcgacttcttcaggtatcacgacagtcacagacagagcctgaacaagctggagcgagtggagcagcttcctcctgaggaactcaaagagctgtgccagggtttggtgtctggttctggtggagtggaaaagatctcatcagtgcagagaaacgtactcgccaaacggagactcgtccagctggtcaacaacagagccaagcttcttgccctctgctcctatatcattgagacgtgtctgtttgtcatctggcgccacctagagttttacttgctttactgcactcccactgaccccaaagactcactgctgccaggttacagagatcctgccggcagcagaggattgagcgtgtcgagagtgagccagcaagatcttgaacagttgcagagtgacatgtcgagcagcttcagtgagccgctgcagaggaagctgctggaggtggagggactttatagcaaaagccgctctcgtcacaccttcatccaggccctgacacgcaggatccgcggcctcgtacaccacgccaaaagctgaactccggcatgcagattttctctaattgtgagaaaagaaaaatcttttgaattcggtgtcttttttgcagttttgatgactatcaatccacacttgaggttttctgcctatgatagtcgctgtattggctttctgcgtttttctaatgtggtcattaaatgcttttctaacagaca
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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