LOCUS       NM_001004289            2216 bp    mRNA    linear   VRT 16-SEP-2024
DEFINITION  Danio rerio splicing factor 3a, subunit 3 (sf3a3), mRNA.
ACCESSION   NM_001004289
VERSION     NM_001004289.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Tseng LC, Zhang C, Cheng CM, Xu H, Hsu CH and Jiang YJ.
  TITLE     New classes of mind bomb-interacting proteins identified from yeast
            two-hybrid screens
  JOURNAL   PLoS One 9 (4), e93394 (2014)
   PUBMED   24714733
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  AUTHORS   Trinh le A, Hochgreb T, Graham M, Wu D, Ruf-Zamojski F, Jayasena
            CS, Saxena A, Hawk R, Gonzalez-Serricchio A, Dixson A, Chow E,
            Gonzales C, Leung HY, Solomon I, Bronner-Fraser M, Megason SG and
            Fraser SE.
  TITLE     A versatile gene trap to visualize and interrogate the function of
            the vertebrate proteome
  JOURNAL   Genes Dev 25 (21), 2306-2320 (2011)
   PUBMED   22056673
REFERENCE   3  (bases 1 to 2216)
  AUTHORS   Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ,
            Mayhall EA, Amsterdam AH and Zon LI.
  TITLE     A genetic screen in zebrafish defines a hierarchical network of
            pathways required for hematopoietic stem cell emergence
  JOURNAL   Blood 113 (23), 5776-5782 (2009)
   PUBMED   19332767
REFERENCE   4  (bases 1 to 2216)
  AUTHORS   Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S and
            Hopkins N.
  TITLE     Identification of 315 genes essential for early zebrafish
            development
  JOURNAL   Proc Natl Acad Sci U S A 101 (35), 12792-12797 (2004)
   PUBMED   15256591
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY648757.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY648757.1, BC096781.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505375,
                                           SAMEA3505377 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="19"
                     /map="19"
     gene            1..2216
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /note="splicing factor 3a, subunit 3"
                     /db_xref="GeneID:446168"
                     /db_xref="ZFIN:ZDB-GENE-040908-1"
     exon            1..224
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    120..122
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /note="upstream in-frame stop codon"
     CDS             129..1634
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /note="spliceosome associated protein 61"
                     /codon_start=1
                     /product="splicing factor 3A subunit 3"
                     /protein_id="NP_001004289.1"
                     /db_xref="GeneID:446168"
                     /db_xref="ZFIN:ZDB-GENE-040908-1"
                     /translation="

METILEQQRRYHEEKERLMDAKTKEMLTKKTTLRDQINSDHRVRAMLDRYMEVSANLRDLYEDKDGMRKDELNAISGPNEFAEFYNRLKLIKEFHRKHPNEICVPMSVEFEELMKAKDNPSEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKGVEKLEYVTYLSTFDQLFDISKDRKNAEYKKYLEMLLEYLQEYTDRVKPLLDQNELYGKILAEFEKKWETGMFPGWPKETSSALTHAGAHLDLSAFSSWEELASLGLDRLKSALMALGLKCGGTLEERAQRLFSTKGKSLESLDPSLFAKNPKAKGPKKDSERNKESAFLEAQIYEYVEILGEQRQLSHENVQRKQARTGEERDEEDEEQPSESESEDEDNEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWSKLKSQKALERWQPDTEEEYEDSSGNVVNKKTYEDLKRQGLL"

     misc_feature    132..1631
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /note="Splicing factor 3a, subunit 3 [RNA processing and
                     modification]; Region: PRP9; COG5188"
                     /db_xref="CDD:227515"
     misc_feature    1272..1631
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /note="SF3a60/Prp9 C-terminal; Region: SF3a60_Prp9_C;
                     pfam11931"
                     /db_xref="CDD:432197"
     exon            225..272
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            273..325
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            326..431
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            432..504
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            505..596
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            597..679
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            680..818
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            819..887
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            888..955
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1063
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1133
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1298
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1409
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1500
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1556
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..2216
                     /gene="sf3a3"
                     /gene_synonym="SAP61; SF3a60; wu:fi15a06; wu:fj94f01;
                     zgc:110227"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atcgcgcgttcttgtttctatccgagttaaataaacgctgaaccggtttcctgtgcgttacacgcgcgtatgcaggttaaactaaacattgtttgaataatcaacgtatcttaaggtaataaaacacaatggaaacgattttagagcaacaacgtcgataccatgaggagaaagagaggctcatggacgctaaaacaaaggagatgctgacgaaaaaaacaacgctgagagaccagatcaactcagatcacagagtgagagccatgctggatagatacatggaagtgagtgcaaacctcagagacttgtatgaagacaaagatggtatgaggaaggatgagctgaatgcaatatcaggaccaaacgagtttgcagaattctacaatcgactcaagctaatcaaggaatttcacagaaagcatcctaatgagatctgtgtgcccatgtcagtggagtttgaggagctcatgaaagccaaagacaaccctagcgaggaggcacaaaacttggtggagttcactgatgaagagggttatgggcgatacctggatctccatgactgctacctaaaatatattaatctaaaaggagtagagaaactggagtatgttacctatctgtcaacattcgatcagctctttgacatttctaaagacaggaagaatgctgaatataagaagtacctggagatgttgttggagtacctgcaggaatacacagatcgcgtcaagcctttgctggatcagaatgagctgtatggaaagattttggcagagtttgagaagaagtgggagactggaatgtttcctggctggccgaaagagacaagtagcgcactgactcatgctggagctcatttggatctttctgcattctcttcctgggaggagctggcgtctctgggtctggataggttgaagtctgctctcatggctttaggcctgaaatgtggaggtacactagaagagagggctcagcgtctgttcagcaccaaaggcaaatctctggagtctctagatccctctctgtttgccaaaaacccaaaagccaagggaccgaagaaagactcagaacgcaacaaggagtcagcttttcttgaagctcagatttatgaatatgtggagatcttgggggagcaaaggcagctgagccatgagaacgtacagagaaagcaggcacgtacaggtgaggaacgtgatgaagaggatgaagagcagcccagtgagagcgagagtgaagatgaagataatgagatcatatacaaccccaaaaacttaccacttggatgggatggaaagccgattccatactggctctacaagttgcatggtctgaacattaattacaactgtgagatctgtgggaattacacatacagaggacctaaagcctttcagagacactttgcggagtggcgtcatgctcatggcatgcgctgtttgggcattcctaatacagcccactttgccaatgtcacccaaattgaggatgcagtatccctgtggtcaaaactgaagtcacagaaagcattggagcgatggcagcctgacacagaggaggagtatgaagactccagtggaaatgttgtcaacaagaagacttatgaggatttgaaacgacagggactgctgtagagtccttaacaacatacacatgaaatttgcgcaatgtaaatactaaagcacatgtttctttcagtcatagtgaatagagcggtgcagaaatagcaataaaacctggaagagtaattagctgtgtgttcctacaggtttctagaattcagtttatcaagtaatatctgtggtaagaataatgtgataatactttagcgttttgctttgcgttgtgaattagacacactcatatcaaaaggtgaatcttaacgccgttttgtatcttttacaaaggaaatttgtttctaaaaagtaacttgaaagtttggtcatgggtttgagtagtttgcattgtagaacagaatgttaaattattgttgaattgtgtaccacaggcctttttattgactggtgatcttgtaagagcctattgaattaataatttgggttgtgatgtcatttctgcatcactcttacattcaaagatttgttcctctagtttgtgtgaaatgtgatttatctttttaatctgattgtacgttattattgttatgtcacattttcttttgggatctcatacattagacagatactttcgttatt

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