LOCUS       XM_030869425            3533 bp    mRNA    linear   MAM 26-NOV-2024
DEFINITION  PREDICTED: Globicephala melas protein argonaute-1 (LOC115860028),
            transcript variant X4, mRNA.
ACCESSION   XM_030869425
VERSION     XM_030869425.2
DBLINK      BioProject: PRJNA1026603
KEYWORDS    RefSeq.
SOURCE      Globicephala melas (long-finned pilot whale)
  ORGANISM  Globicephala melas
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha;
            Cetacea; Odontoceti; Delphinidae; Globicephala.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_083314) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 24, 2023 this sequence version replaced XM_030869425.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963455315.2-RS_2024_11
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 11/21/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3533
                     /organism="Globicephala melas"
                     /mol_type="mRNA"
                     /db_xref="taxon:9731"
                     /chromosome="1"
     gene            1..3533
                     /gene="LOC115860028"
                     /note="protein argonaute-1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     Proteins"
                     /db_xref="GeneID:115860028"
     CDS             127..2256
                     /gene="LOC115860028"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X4"
                     /protein_id="XP_030725285.1"
                     /db_xref="GeneID:115860028"
                     /translation="

MPHRVGACARGTSSLPVPARYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    193..345
                     /gene="LOC115860028"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    346..708
                     /gene="LOC115860028"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(502..504,547..549,589..591,601..603,655..657,
                     676..678,682..684)
                     /gene="LOC115860028"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    841..2127
                     /gene="LOC115860028"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1261..1263,1273..1275,1309..1320,1327..1329,
                     1351..1353,1360..1362,1372..1374,1384..1386)
                     /gene="LOC115860028"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1465..1467,1471..1473,1681..1683,2095..2097)
                     /gene="LOC115860028"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      3533
                     /gene="LOC115860028"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gctggcgcatgctgcatgaggccttggttagtggccagatccccgttcccctggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggccagggctcctccgtgcccaggatgcctcacagggtgggggcctgtgcccgagggaccagttctctgcctgtccctgccaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaggcgcagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagcccctcacggactctcagcgtgtgcgcttcaccaaggagatcaagggcctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgcgtgtgtaatgttacccgccgccctgccagccatcagacgtttcccttgcagctggagagtggacagactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcctgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagctgactgacaaccagacttcaaccatgataaaggctacagctagatcggccccagacagacaagaggagatcagccgcctgatgaagaatgccagctacaacctagatccctacattcaggaatttgggatcaaggtgaaggatgacatgacggaggtgacggggcgagtgctgccggcgcccatcttgcagtacggcggccgggtgagcaggaaccgggccattgccacacccaatcaaggtgtctgggacatgcgggggaaacagttctacaatggaattgagatcaaagtctgggccattgcctgcttcgcaccccaaaaacagtgtcgagaagaagtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaagcgtgttggagatacactcttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcgcctcagactctgtccaacctttgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagttccacaccaacgctctgctgtctttcaacaaccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgttactgtgctactgtgcgggtgcagcgacctcggcaggagatcattgaagacttatcctacatggtacgtgagctgctcatccagttctacaagtccacccgcttcaagcctacccgcatcatcttctaccgagatggggttcctgaaggccagctcccccagatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcccgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttacgtacgatgcacacgctccgtctcaattccagcacctgcctactatgcccgcttggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgccgcccaaatccagaggaagcagggaggagggaggtggggcagggaggaatgcagaaggccttgtttcctctacagagggggcgaaagggtggggaacagggccagtaagccagaccaccagccagaaatctctgatattcacctcatgccctccacccctcaccccatcttgtcacatctggccctgactccactggaccaagagaggcagccccggtgcccaccatacacacagatgtcgcatgtgactcacagtgctaaagactcatgcctgacagcttggtaaggtcggccctgcagccctgcagacaaaagctggtaggtttgggtttgatactttagatgggaaagtgaggggcttgaaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaacgaaaccagatgcagatcaatattttaggatactagatgttttaatgggttgagaatccagcttgtaggaagatttttaatgctaatgatttggttgcccctcccccagctgccactcctctttcccttattcctctttttccaccttttctaccccaccttacaccttctccctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctatttttgggggggtgggggcggggtgggggtgggagaggaggtaggtggggatgaaatacccctaacccaacaagcctccagccagagcgccagctactttgcatttgaaggagttgacttccatattcattgagcttttaaaaagatcgccacctcaagatggttaaaatccattgacatttgcactttcagacatgacaagtctctcggagctgctgaggtgactggcctctggcctttccacttacgtctcctttcttcctgtccctgcttcctccccacctgcctgggtctggagttactttcatagcatttctcactcttggcttcttttttttccctgacgatcaagtctgtttatgtttcaatattttttaactggggtgtcttttaacaaacgatccttaggtctaaaataagaaaaaaaaaaaaaagcaaaaactaaatgttattttta

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