LOCUS       XM_029737621            3310 bp    mRNA    linear   VRT 10-JUL-2025
DEFINITION  PREDICTED: Salmo trutta protein argonaute-3 (LOC115177110),
            transcript variant X3, mRNA.
ACCESSION   XM_029737621
VERSION     XM_029737621.1
DBLINK      BioProject: PRJNA550988
KEYWORDS    RefSeq.
SOURCE      Salmo trutta (river trout)
  ORGANISM  Salmo trutta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Salmo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_042993.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_901001165.1-RS_2025_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/09/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3310
                     /organism="Salmo trutta"
                     /mol_type="mRNA"
                     /db_xref="taxon:8032"
                     /chromosome="37"
     gene            1..3310
                     /gene="LOC115177110"
                     /note="protein argonaute-3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     Proteins, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 8 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:115177110"
     CDS             812..3310
                     /gene="LOC115177110"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X3"
                     /protein_id="XP_029593481.1"
                     /db_xref="GeneID:115177110"
                     /translation="

MEIGTTGAVGAQPLFTVPRRPGYGTMGKPIKLLANCFQVDIPKIDVYLYEVDIKPEKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATAGVDLDVTLPGEGGKDRPFKVSIKFVSLVSWHMLHEVLTGRSVPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYESDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRVSTEHFMNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPIIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACIGLEKEYQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDR"

     misc_feature    1028..1312
                     /gene="LOC115177110"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    1340..1492
                     /gene="LOC115177110"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1493..1855
                     /gene="LOC115177110"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1649..1651,1694..1696,1736..1738,1748..1750,
                     1802..1804,1823..1825,1829..1831)
                     /gene="LOC115177110"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1988..3286
                     /gene="LOC115177110"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2420..2422,2432..2434,2468..2479,2486..2488,
                     2510..2512,2519..2521,2531..2533,2543..2545)
                     /gene="LOC115177110"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2624..2626,2630..2632,2840..2842,3254..3256)
                     /gene="LOC115177110"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

cgaagtgcttcattctgacgtttggcgtttcctatttgagatagaacccacctcttcctgtcggtgccagagtagtaacttcaccatatttagttggtcagagccctacagagttgagcacaggcaaccgggatgaaaaccttagccatatcgacgaatgcaaccgggagttgacagcctagaaacagcgagactggccgctgttggagagtgacatcagtggaaacaaggctgcacatatcgttagcagactttgagtgataagtagctgtctaatgtcggatgagaattcgaactagtagtcgtaggtaactagatggctagctagctaattatcgccaactagcaagccttaaactcgatttcttctggacgtaaaactgaacgtgtcagatttttattcagcaaactggtaataaactaaagagaccagtgaatctgcaattatgatatcttgacattgtctgttagctatgcttgtctcaatccatttgctaatctagcagctagctagtttatcatcgtcgttgaggctcgagccagtatcgccgtggcagtgtattctgattggataccttgatcgtgtgaacgacttgcagacaccgggacacggaagaccctcatccaaagggactggaaaaggggcccgtttgacagtgagtagagaggagaattcgggggaacccgtaactactcggttgcatcgcctgtacggcattgtgaactgccgataaaccagattgaaccaagcaagagttcctgacatttgtcatctgtgatccggggagtgaaccggacagggacctcatgaatggaaatcggaacgacaggagccgttggagcccagcccctgttcactgtgccacggcggcctggctatggcaccatgggaaagcccatcaagctgctggccaactgcttccaggtggatatccccaagatagacgtctacctctatgaggtggacatcaagcccgagaagtgcccgcgccgcgtcaacagggaggtggtggactccatggtgcagcacttcaaggttaccatctttggggatcgtcggccagtctacgatgggaagaggagcttgtacacagccaacccgctgccagtggcaaccgcaggggtggatctggatgtcactctaccgggtgaggggggcaaggaccggccctttaaggtctcaatcaagtttgtgtctctggtgagctggcacatgctgcacgaggtgctaaccggccgcagcgtgcctgagcccctggagctggacaagcccatcagcaccaacccagtacatgctgtggacgtggtgctgcgacacctgccctccatgaagtacactccagtgggtcgctccttcttctcagccccagagggctacgaccatcccctgggaggggggagagaggtgtggtttggtttccaccagtctgtacgccccgccatgtggaagatgatgctcaatattgacgtgtctgccacggccttctacaaagcccagccagtgatccagttcatgtgtgaggtcctggacatccacaacatagacgagcagccccgacctctcacagactcccaccgggtcaaattcaccaaagaaatcaaaggtctgaaggtggaggtcacacactgtggcaccatgcggaggaagtaccgcgtttgcaacgtgacccgtaggcccgccagccatcaaacattccctctgcagctggagaatggtcaaacggtggagcgcacggtggcccagtacttcagagagaagtacagcctgcagctcaaatatccccacctgccctgcctccaggtggggcaggagcagaagcacacctacctgcccctggaggtgtgtaacatagtagcagggcagcgctgcatcaagaaactgacagataatcagacgtccactatgatcaaggccacagctcgctctgcacctgacagacaggaggagatcagccgactggtgcgcagtgccaactacgagtctgacccctttgtgcaggagttccagttcaaggtgcgcgacgagatggcccacgtgactgggcgcgtgctgcctgcccccatgctgcaatacggcggcagggtgagcacagagcactttatgaaccggacggtggccaccccaagtcacggggtgtgggacatgaggggcaaacagttccacacgggagtagagatcaagatgtgggccatcgcatgtttcgccacacagaggcagtgtcgcgaggagatcctcaagggtttcacagaccagctgcgtaagatctccaaggatgctgggatgcccattcagggccagccgtgtttctgtaaatacgcccagggagctgacagtgtggagcccatgttcaggcacctgaagaacacctactctggactgcagctcatcatcgtgatcctgcctggaaagacccccgtctacgcggaggtgaagagggtgggagacactctcctaggaatggccactcagtgtgtccaggtgaagaacgtggtgaagacgtccccccagaccctctccaacctctgcctcaagatcaacgtcaagctgggaggaatcaacaatatcctggtgccccaccaacgaccctcagtattccagcagcctatcatcttcctgggggcggacgttacacacccccctgctggagacgggaagaagccctccattgctgcagtggtaggcagtatggatgcacaccccagcaggtactgtgccacagtcagggtccagaggcccaggcaggaggtgatccaggatctggcctctatggtccgagagctgctgatccagttctacaagtcaacccgctacaagcccaccaggatcatcttctacagggacggagtgtcagagggccagtttagacaggtgttgtactacgagctgctggccatccgcgaggcatgcattggcttagagaaggagtaccagcccggcatcacctacatcgtggtccagaaacgccaccacacccgcctcttctgtgccgaccgcaacgaaagagttggacgtagtggaaacattcctgctggcaccacggtggacacggacatcacgcacccctacgagtttgacttttacctctgcagtcacgctggaatacaggggaccagtcggccctcccactaccacgtcctgtgggacgacaactgcttcacggccgatgagttccagctgctcacctaccagctgtgccacacctacgtgcgctgtacccgctccgtctccatccccgcgccagcctactacgcccacctggtggccttccgtgcccgctaccatctggtggacaaggagcacgacaggtga

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