LOCUS       XM_024430304            4054 bp    mRNA    linear   VRT 08-JUL-2021
DEFINITION  PREDICTED: Oncorhynchus tshawytscha NRDE-2, necessary for RNA
            interference, domain containing (nrde2), transcript variant X1,
            mRNA.
ACCESSION   XM_024430304
VERSION     XM_024430304.2
DBLINK      BioProject: PRJNA432585
KEYWORDS    RefSeq.
SOURCE      Oncorhynchus tshawytscha (Chinook salmon)
  ORGANISM  Oncorhynchus tshawytscha
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_056436.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jul 8, 2021 this sequence version replaced XM_024430304.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Oncorhynchus tshawytscha Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4054
                     /organism="Oncorhynchus tshawytscha"
                     /mol_type="mRNA"
                     /isolate="Ot180627B"
                     /db_xref="taxon:74940"
                     /sex="male"
                     /tissue_type="blood"
                     /dev_stage="Mature"
                     /country="Canada: British Columbia, Capilano River"
                     /linkage_group="LG08"
     gene            1..4054
                     /gene="nrde2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 18 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:112256795"
     CDS             147..3728
                     /gene="nrde2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X1"
                     /protein_id="XP_024286072.1"
                     /db_xref="GeneID:112256795"
                     /translation="

MTSHSCDCLHAEAINMALFPAFAGLSNTKAEIAPKELEWLSNQSFRTDDALSLHQRATEKANETQSAETSRHVIPEREDKNDVQSNKKKKKEKKKKKKKKKKHKKKSGEPSPASSGSDSDTIYPSDLLKKAESTPPSEEFQVEGSFVWLDDLQTPTDQPFCVDRRADRANWEYKSLYRGDIARYKRKGSSSLGLNLRSQAVSWAESGPEKKRVDRRQRPNRYFSPTVRQLLMSDGKPTLPRPPPEDTTTTTLPFIPVPSCLEGEAEGGGSAKGQGSWVNPLGVYDSSTSLWLQGKGKAEHGKAEEQPSTPRDNAAIMLAERVEDFNRRLRETPTDTHTWLQFVLFQDEVAGAPGVFADISENESERRKRSVRATLEKKVAILDRAVENNPSCVELKLERLRLCRELWEPAALLKEWKKLVFLHPNSAPLWRKYLLFMQSHFSTFSVSKVNTVYGKCLSTLAAVQDGSMVSHQMLPGTDEHMLAIFLQQCHFLRQAGHSEKAVCLFQGLLDFTFFKPDTVKDLPTRQQVEFFEPFWDSGEPRVGERGASGWRAWMTQQERGGWLQPSEQDDGDEEDQEELEVKDKTWPKWRIWLDVETSREAIHWLPWRPDKTKGQSVEDCEDPDRQVLFDDIGPSMIRLVRPDLQLCLLLSFLHFLGLPADTSCYSAPSCSLLLDDQALLGDVHHPDSPLTSYALLVPGVSPVGHMTSLQGARRGVGLCKQGEEFVDNVFQMVLPLFSAQERAVLSLHWIQYEKLKVLRCVRGRNKKRVKSQGKRSKRLAKRLLKEPENRGRLSLWREYAHLEWLLGNLDEAHKVFDTALGLGVAGGLADPALCDLCLLYAQLEVEEAWRRDTGGAGTTVTTAMSSPAVYILTKLAEGSSYAPFLGQLAPVAVLKARKAYEQAVVSSLPGQEEGAAGQGQSKSRQVKGLVGCYALFQYLTVGVDAADAVYNLARKRLEQHSSMSAQQSASSEVMCDIQTLSSVSECEALAVQQVALLRYHTSTNVYPLSHIRLALTSALAHFASSTSLWQLYVQVENRYHSAGRARRFFHSVTKASTSVVPRLFAISAEQQRKQLVDSVQRSDCYGDTVSSLPENGLSNRIRSLFENAIATEHGVHCPLLWRMYMNFLVSEGKVEKGRGIFYKALQDVPWAKGLYMDAVQLFPEHVQEFLDLMTEKELRLRVPMEEVDILLED"

     misc_feature    621..923
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(621..647,654..659,669..674,678..680,684..728,
                     735..743,747..755,777..785,801..806,810..815,822..842,
                     864..875,894..923)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1119..2117
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:429988"
ORIGIN      

gagatgtcgcttctcattggatacagtggacctgcaatattctgcccaatgtacgggagcccacgattggctacgttggatctgcaatgcgtcaaacaatggcgcctaatattacctgagtagtttaggaaaacggcgcgttcgagatgacgtcacattcatgcgactgtttacacgcagaggctatcaacatggcactatttccagcttttgctggattatcaaatacaaaagctgagattgcacctaaagaactagaatggctgagcaatcaaagtttccgcactgatgacgctctctctcttcaccaacgagccactgagaaagccaacgaaacacaatcggcagaaacaagcagacatgttataccagagagggaggataagaatgatgtccaatccaacaagaagaaaaagaaggagaagaagaagaagaagaagaaaaagaagaagcacaagaagaagagtggagaaccctctccagcaagcagtggctcagattcggatactatctaccccagtgacctcctaaaaaaggctgagagcactcctcccagtgaggagtttcaggtggaggggtcttttgtgtggttggatgacctacagacccccaccgatcagcccttctgcgtggacaggagagcagaccgtgccaactgggagtacaaatcactttacagaggagatatcgctaggtacaaaaggaaaggctcttcctctctgggtttgaacctgcggtctcaggccgtgagctgggctgagtctggcccagagaagaagagagtggacaggagacagagacccaaccgctacttctcccccaccgtccgccagctgctgatgtctgatggcaaacccacgctgcccagacctccaccagaggacaccacaaccaccaccttacccttcatccctgtgccctcatgtctggaaggtgaggcagaggggggtggctctgccaaaggccagggctcctgggtcaaccccctgggggtgtatgactcctccacgtccctgtggctccaggggaaggggaaggcggagcatggcaaggcagaggaacaaccttctactcccagggacaatgctgccatcatgctggctgaacgggtggaggacttcaataggaggttgagggaaacccccacagacacacacacctggcttcagtttgtcctcttccaggacgaggtagctggggcgcctggggtgtttgctgacatctctgagaacgagagcgagcggcggaagaggtcagtgcgggccacgctggagaagaaggtagccattttggatcgagcagtggagaataacccgagctgcgtggaactgaagctggagcgactgcggctctgtagggagctgtgggagccggcagccctgctgaaggagtggaaaaagctggtgttcctgcaccccaacagcgcccccctgtggaggaagtacctgctgttcatgcagagccacttcagtaccttctccgtgtcaaaggtcaacacggtatacgggaagtgtctgagcacgctggcggcggtgcaggatgggagcatggtttctcaccagatgctgccgggcactgatgaacacatgctggccatcttcctccagcagtgtcatttcctcaggcaggctggccactcagagaaagctgtgtgtctgttccagggcctactggacttcaccttcttcaagccagacactgtcaaggacctacccaccagacaacaggtggagttctttgagccattctgggacagtggggagccccgtgtcggggagagaggggccagtggatggagagcctggatgacccagcaggagagagggggctggctccaacccagtgaacaagatgatggagatgaagaagatcaggaggaattggaggtgaaggataaaacctggcccaagtggaggatctggttggatgtggagacgtcacgcgaggccatccattggctgccatggaggccggacaaaaccaagggccaatcggtggaggactgtgaggacccggaccgacaggtgctgtttgatgacattgggccgtctatgatccggctggtccgcccagacctccagctatgtcttcttctgtccttcctgcacttcctgggtctgcctgctgacacttcctgttacagcgccccctcctgtagcctgctgctggatgatcaggctctactgggggatgttcaccaccctgactcaccactgacctcttatgccctccttgttcctggggtcagccccgtgggtcacatgacctcactgcagggtgccaggaggggggtggggctgtgtaagcagggggaggagtttgtagacaatgtgttccagatggttctgcctctgttctctgctcaggagagagctgtcctctcactacactggatccagtatgaaaagctcaaggtgctgaggtgtgtgcgcggcaggaacaagaagcgtgtgaaatcccaggggaagaggagcaagcgcctggccaagcgcctgctgaaggagccagagaaccggggccgcctcagcctgtggagggagtacgcccacctggagtggctgctagggaatttggacgaggcccacaaggtgttcgacacagccctgggactgggcgtggcaggagggctggcagaccctgccctgtgtgacctctgcctgctctacgcccagctggaggtggaggaggcctggcgaagggatacgggcggggcagggacgactgttacgaccgccatgtcttcaccagcggtctatatcctcaccaagctagcagagggtagttcgtatgcccccttcttgggacagttggctccagtggccgtgctgaaggccaggaaggcctatgagcaggctgtggtgagctccctgcctgggcaggaggagggggctgcggggcaggggcaatccaagtccaggcaggtcaaaggtctggtggggtgttacgccctattccagtacctgactgtgggggttgatgctgctgatgctgtctacaacctggccaggaagaggctggagcaacactccagtatgtcagcccagcagtcagctagcagtgaagttatgtgtgacatacagacactgagttctgtctcggagtgtgaggccctggccgtccagcaggtggcgctgctgcgctaccacaccagcaccaacgtctacccacttagccatatcagactggcgctgacctcggccctggcccactttgcctccagcacgtctctgtggcagttgtatgtgcaggtggagaaccgctaccatagcgctggcagggctcgccgcttcttccacagcgtgaccaaggctagtaccagtgtcgtgccacgtctgttcgccatcagcgcagagcagcaaaggaagcagctagtggactctgttcagaggtctgattgctatggtgacaccgtctccagcctgccagagaacggcctgagcaaccgtatccgctcgctgtttgagaatgccatagcaacagaacacggggtccactgtccgttgctgtggaggatgtacatgaacttcctggtctcagaggggaaggtggagaagggaagaggtatcttctacaaggctctacaggacgtcccatgggcaaagggtttatacatggacgcggtgcaactcttccctgagcacgtgcaggagttcctggacctgatgaccgagaaggagctcagactgagggttcccatggaggaggtggacatactgctggaggactgaggctctaaaacccttcccacagtgcactggggcctggcttcctcagacactccactgtggatacccgaagttgtgcactgaccaatagaacaaccaagtgtcctcatgaagaagaccattttacttttcaaacagacgtgtgaataaatgatgttacacttattagtgttaattcaatattttgatggattgcaaatccatatttttatatttccagctttttatggattcttaatccatattttgattaacataatatcctatttttctgtcaaagatttgttttgaaacattttttttttttttaaatggactgaaataaatgt

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