LOCUS       XM_021659924            7377 bp    mRNA    linear   ROD 25-OCT-2023
DEFINITION  PREDICTED: Meriones unguiculatus argonaute RISC component 1 (Ago1),
            transcript variant X2, mRNA.
ACCESSION   XM_021659924
VERSION     XM_021659924.2
DBLINK      BioProject: PRJNA1030069
KEYWORDS    RefSeq.
SOURCE      Meriones unguiculatus (Mongolian gerbil)
  ORGANISM  Meriones unguiculatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Gerbillinae; Meriones.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_083351) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 25, 2023 this sequence version replaced XM_021659924.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030254825.1-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/23/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7377
                     /organism="Meriones unguiculatus"
                     /mol_type="mRNA"
                     /strain="TT.TT164.6M"
                     /db_xref="taxon:10047"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="liver, kidney, testi"
                     /dev_stage="adult"
                     /collection_date="2020-06-17"
                     /collected_by="Tom Brekke"
     gene            1..7377
                     /gene="Ago1"
                     /note="argonaute RISC component 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3 long
                     SRA reads, 47 Proteins"
                     /db_xref="GeneID:110562993"
     CDS             229..2802
                     /gene="Ago1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X2"
                     /protein_id="XP_021515599.1"
                     /db_xref="GeneID:110562993"
                     /translation="

MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    328..720
                     /gene="Ago1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:406799"
     misc_feature    748..900
                     /gene="Ago1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:400854"
     misc_feature    901..1263
                     /gene="Ago1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1057..1059,1102..1104,1144..1146,1156..1158,
                     1210..1212,1231..1233,1237..1239)
                     /gene="Ago1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1396..2673
                     /gene="Ago1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1807..1809,1819..1821,1855..1866,1873..1875,
                     1897..1899,1906..1908,1918..1920,1930..1932)
                     /gene="Ago1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2011..2013,2017..2019,2227..2229,2641..2643)
                     /gene="Ago1"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      7377
                     /gene="Ago1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cggtcgcgcctgcgcactggcagctactcgggcgctcgcagggggagctgctgcaggctccgcggcggcggcaacggaggctgcgggggcgacggcgctagcggccgggcttcggggggaagccgagcccggcccgggagcccgagcagtgcaagtgcgaggcacctaggcccctcacgctggactcctcagtctcccggacgcctgtcctccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcaggcgcctacctgcctcccctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtgggcaaaccaatcaagcttctggccaattactttgaggtggacattcctaagattgatgtttaccattacgaggtggacatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggaatacatggtccagcatttcaaacctcagatctttggggatcgcaagcctgtgtatgatggcaagaagaacatttacaccgtcacagcactgcccattggcaatgagagggttgactttgaggtgacaatccctggggaagggaaggataggatttttaaggtctccatcaagtggctcgccattgtgagctggcgcatgctgcatgaagccctggtcagtggccaaatccctgtgcccttggagtctgtgcaagctctggatgtggccatgaggcacctggcatctatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctctgccactgccttctacaaagcacagccagtgattgagttcatgtgtgaggtcctggacatcaggaacatagatgaacaacccaagcccctcacggactcccagcgtgttcgctttaccaaggagataaaaggcctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgcgtgtgtaacgttacccgccgccctgctagccatcagacgtttcccttgcagctggagagcggacagactgtggaatgcactgtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcctacaagttgggcaagaacagaagcacacctatctgcccctcgaggtctgtaacattgtggctgggcagcggtgcattaagaagctgactgacaaccagacttcaaccatgataaaggctacagctaggtcggccccagacagacaggaggagatcagtcgcctgatgaagaatgccagctacaacttagatccctacatccaggaatttggaatcaaagtgaaggatgacatgacggaggtgacggggcgagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgctacacccaaccaaggcgtctgggacatgcgtgggaagcaattctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccagaaacaatgtcgagaagaggtgctcaagaacttcacggaccagctgcggaagatttccaaggatgcagggatgcccattcaaggccagccatgtttctgcaaatatgcacagggggcagacagtgtggagcccatgttccggcatctaaagaacacctactcgggactgcagctcattatcgtcatcctgccggggaagacaccagtgtatgctgaagtgaaacgtgttggagatacactattgggaatggcaacgcagtgtgtgcaggtgaagaatgtggtcaagacctcacctcagactctgtccaacctctgcctcaagatcaatgtcaagctcggtggcattaacaacatcctcgtcccacaccagcgctctgctgtttttcagcagccagtgattttcctaggagcagatgttacacaccccccagctggggatgggaagaaaccgtctatcacagcagtggtgggcagtatggatgcacaccccagccggtactgtgctactgtgcgtgtgcagcgcccacggcaggagatcatcgaagacttgtcctatatggtgcgtgaactgctcatccagttctacaagtccactcgcttcaagcccacccgtatcatcttctaccgagatggggtacctgagggtcagctcccccagatccttcactatgagctgcttgccattcgagatgcctgcatcaaactggagaaagactaccagcctgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccacccgtttgagtttgacttctatctgtgcagccatgcgggcatccagggtaccagccgaccatcccattattatgtcctttgggatgacaaccgtttcacagcagatgaactccagattttgacataccagctgtgccacacttacgtacgatgcacacgttctgtctctatcccagcacctgcctactatgcccgcttggtggctttccgggcacgataccacctggtggacaaggagcatgatagtggagaggggagccacatctcggggcagagcaatgggcgagatccccaggccctcgccaaagctgtgcaggttcaccaggatactctacgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccctgggagctgtaccacccaaatccagaggaagcaaggaagagggaggtggggtcgggaggagtctaggaggccttgtttctatctacagaggggagataagggtgggaaaaggaccagcaagactgactaccagccagaaatctctgatagcaacctcatgtcctccacccctctccccatcttgtcacatctgaccccagtggaccaaaaggagcagcactagtgcccaccatacacacagttgtctcacgtgactcacagtgctaaagactcatgcttgacagctcactagggtcagctctgcagtcctgcggtcaaatgctggtatgcttgggtttgataattctagatgagaaagtgggtgggaggagggaaggaatttttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaatgaaaacagactcagatcaatattttagaatactagatgttttcatgggttcagaatccagtttgtaggaagatttttaatgctaatggtttgggttgctcctccccagctgccaccccctcccattatatgttttctaccccatacgtctcttccctgacagacatccagcccctagtaacacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttgtgggatggggtatgggtgggagatgagataggtagagagggaagagatatcccagcgccagcaagcctccagccagaatgccagctatttttcatttgaaggaattgacttcaatattcattgagcatttaaaaaaaaattacaacctcaagatggttaaaatccattgacatttgcactttcagacaagacaagtctccaagctgctgagatgactggcccttggcctttcccctttagcctcctcttttccctggccctataccccccaccctgtcaggtctagagttaccctcatagcatttctcattcttggcttcttttcccccagatggtcaagtctcttttgtttttaatatttcttaactggggtgtcttataacagaagatctttaggactaaaataagaaaacagaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaagtccctcccatactggatgagtttgcatcccaggaacatggagctgtcagcaggaactgtggagctgactattctggcctggctatgtaggggtggttgtcccccaaggtagggatcagccgcagtcattccgctgtgcagataatacctttttcttgctacagcctccctctgctgccctgtcctgcactctttcttgtaagtgtgtcttccctttttctggactggactgtcctttgatcctttgactaaccgagattctagcatgtcttctggacaggctggagaattttgctgctcccttttgcttctgtttacacaaatgaatttttttctgtttcccactaaggcatgtgagtgggtggcataggctttttttctccccctctcaagatactggagttcagctgtcttgcaggactggaaaagaagtaggttctagctttgtccttgctgaccttaaagcaagggcccctcttcccttgactgttctctttttactcctgcattactgcttgggatggggagtttgaacttgggtgtacagatccctgtctaaggagcttgagcttagttttgttctgctctggtgatggagcaatgatattttacatctaggccaggcttagagggcagccggagaaaggaaggtccatatcctgggctgtggaatcaaaacctgtccctagcagccattggacagacccagatttgctatgcaaatagtccaggttcagttatggctggctacattgttcagtaacttcccaaaaggtagcacaaacattccttctggaaaaagcccaggactgttaagtagttcctcctgtactttttttctgctggctatagtatggagtgccccgtgggcacaagcccagccgaagaacagaacagagggctctgggaagaggcagctcactggagagcctacattccttacacaagtgcctaaacagagtgatgccaacactccatctgccctgtccatcgccttcatacacagtatacttcgtgttccgtcaccctttggggagggagctcttcgcacacagtgtgctgtcaacttgggtacatttggggccttggataagggcactattcctggagggtccagtcatttcaccagcatttgcagatgcccataaggaacaggtggctgtcataactcccagcaacaagtttttgttctctccttttttctttgcctcactctctctagttgtgtttcaagctagggattaaaaagcagtcttagtccattggtatttatgtgccattcaagaaataaaagcaaaagaatactgggggcatgatgtcccatgtctgtaattctataaaatctcagcactgaggctgaagcagatttacaagttcagggtccacctgggctgctcagtgaattccaggccattgtgtactacatagcaagaccacgtctcaaaaaaaaaggaagagcgagataaataacttgggtgatacagcttcctgctgtgattttaaaaaacaaacaaatcttttgagacttaactactactgaccaggtgggttcttcccatttaaagacggtacacacacattaaaagtggtgttgtcaagcttgtttggatttggtttaagtggtgcattgtaccgagctctgggaggattccaatctcatcttggacagatctctttctccttttccctcacccctactattctgctttccttttcctcttctcgctttccctggcttccttttccctcttcactcagcttgcttgctggctggcctgcctgcctgtctgcctgtgtgataatgaattctctgcatggctgcaatgatcccactgttagttggcaaggtcaggcttagttcattgactacagaagaccaaaaacctgtttcccatgcctagtggtgttaaccctggcttgcactgtcctcaagcttatactaggtcagagcagcaggcctgtctaactgacaaaatcagtagggtttctggcagtttcaacactttcatttggtggagctctttgctgagagtgccctagggtagccgggtagaggacagatatagaggaagagagtaaaaagaaaatggagagtttggataagatgtggtaaaggagaatgctgctttgtattcactccagtgtgacctattggttgaggtgctattgccagccacttgggataggcctggagctaccattactgggaacttgggatgcttggactatgaataaagctgaacaaagctaagtatgaaactactctaaaaatctggttctcaactgcaacatagctcttctttggcctcctctttggctaagcagcaatggttttggacagttttctttttaaccaggattatgtgaatgatgccagggacacagttttcttagctggcccatggaatgcctacaaggctgctcagtgttgtagacctggcatcaggcagcatgaaggaggatggagttactttccctttaaggtagaagagtcacctcttacctagccaaaaggcaatttggaaattcatgttggggaaaggttttgtttaatttactggactttagataacccaggatggtcgttaagatgctttccttgagcagggatcatggcagggatatgcaaggcactcttctactcggccttctaagcagactgggaaagggggattctctggtttttctctttcttcccacttactcggacttgccttctccctgagccacgagagaggctgggttggtgctctccccttactctgctcctactgacttagaacctctggctgctgtatgatagcccaggaaagggaatggaaagaatgggctcaaaacaaaacagaacaatgtaaggaaggcagatttccttccttaaaaagggaaatcagaaactctgcaagaattgtgtgagtaaagacaatgtgtctgaatgcactgagtcctctggtgtcatagcaataaggaaaaatgaaatgacttcctgtgcacacagtccaacctgattgctgtatgatgttgcacttagcagccatgtggtgggcatgtgtgactactctgggtttcactttattttctaaactttttattcctctcaagtccagcatggatggggaaatgtccctgaagccccgcagctgtgtacttgtttgcatttgtttcccattgagacttgtgtttgtgtcctgctttgagctgtaccctgtcccgtccattgtgaaattatcccagcagctgtaatgtacagttccttctcaagcaagcaacagcagcacaatcctgtgttttataaagacaacagtggcatttatttctaaa

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