LOCUS       XM_021183054           11177 bp    mRNA    linear   ROD 10-JUN-2019
DEFINITION  PREDICTED: Mus caroli argonaute RISC catalytic component 2 (Ago2),
            mRNA.
ACCESSION   XM_021183054
VERSION     XM_021183054.2
DBLINK      BioProject: PRJNA387030
KEYWORDS    RefSeq.
SOURCE      Mus caroli (Ryukyu mouse)
  ORGANISM  Mus caroli
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_034584.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jun 10, 2019 this sequence version replaced XM_021183054.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Mus caroli Annotation Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11177
                     /organism="Mus caroli"
                     /mol_type="mRNA"
                     /db_xref="taxon:10089"
                     /chromosome="15"
                     /sex="female"
     gene            1..11177
                     /gene="Ago2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 10 mRNAs, 35 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 8 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:110310268"
     CDS             166..2748
                     /gene="Ago2"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_021038713.1"
                     /db_xref="GeneID:110310268"
                     /translation="

MYSGAGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"

     misc_feature    184..2742
                     /gene="Ago2"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:215631"
     misc_feature    1342..2619
                     /gene="Ago2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1753..1755,1765..1767,1801..1812,1819..1821,
                     1843..1845,1852..1854,1864..1866,1876..1878)
                     /gene="Ago2"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1957..1959,1963..1965,2173..2175,2587..2589)
                     /gene="Ago2"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gctcccgccgcctccgcccgccgccccggccgcgtcgggtaaacctgttctgcgaggcggccgcgccggggcggatcgagcggccggcggctcctcgcggctcgcggcgtcggggcccgtggagcgcgcggccggccctcggccgcggccctcggcaacgccaccatgtactcgggagccggccccgttcttgcttctcctgctccgacaacatcacccatcccaggatatgccttcaaacctccacctcggccggacttcggcaccaccgggagaacaatcaaactacaggccaatttctttgaaatggacatccccaaaattgacatctatcactatgaattggacatcaaacctgagaaatgccctcggagagtgaacagggaaatcgtggagcacatggtccagcactttaaaactcagatcttcggggaccggaagccagtgtttgatgggaggaagaatctgtacacagcaatgccccttccgattggcagggacaaggtggagctggaggtcacgctgccgggagaaggcaaagatcgcatctttaaggtatccatcaagtgggtgtcgtgcgtgagcctgcaggcattacacgatgcactttcggggcggctgcccagcgtccccttcgagacgatccaggccctggacgttgtcatgaggcacttaccatccatgaggtacaccccggttggccgttccttcttcactgcgtctgaaggctgttccaaccctctaggtgggggcagagaagtgtggtttggcttccatcagtccgtccgaccttctctttggaaaatgatgctgaatatcgatgtatcggcaacagcgttttacaaggcacagccagtgatcgagtttgtttgtgaagttttggattttaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtaaagtttaccaaagaaatcaaaggtctaaaggtggagataacgcactgtggtcagatgaagaggaagtaccgtgtctgcaatgtgacccggcggcctgccagtcaccaaacgttcccactgcagcaggagagtgggcagacagtggagtgtacagtggcccagtacttcaaggacaggcacaagctggttctgcgctacccccacctcccgtgtttacaagtcggacaggagcagaaacacacctacctacctttggaggtctgtaacatagttgctggacagagatgtataaaaaaattaacagacaatcagacctcaaccatgatcagagcaactgccaggtcagcacctgatcgccaagaggagatcagcaaactgatgcgaagtgcaagtttcaatacagacccatatgttcgtgaatttggaatcatggtgaaagatgagatgacagatgtgactgggcgggttctgcagccgccctccatcctctacgggggcaggaacaaagcaattgccacccctgtccagggtgtgtgggacatgcgaaacaagcagttccacacaggcatcgagatcaaggtgtgggccatcgcctgcttcgccccccagcgccagtgtacagaagtccatctcaagtccttcacagagcaactgaggaagatctcgagagatgctgggatgccgatccagggtcagccctgcttctgtaaatacgcacagggtgcagacagtgtggagcccatgttccgacacctgaagaacacatacgctggcctccagctggtggtggtcatcctgcctggcaaaactcctgtgtatgcggaagtcaagcgtgtgggagacacagtgctggggatggccacacagtgcgtccagatgaagaacgtgcagaggaccacgccacagaccctatccaatctctgcttaaagatcaatgtcaaactgggaggcgtcaacaacatcctactgccacagggcaggcctccagtgttccagcaacctgtcatcttcctgggagccgatgtcacccacccaccagctggggatgggaagaaaccttctattgctgccgtcgtgggcagcatggacgcacaccccaaccgctactgtgccaccgtgcgtgtgcagcagcaccgacaggagatcatccaggacctggctgccatggtacgagagctgctcattcagttctacaaatctacccgcttcaagcccacccgaatcatcttctaccgagatggcgtctccgagggccagttccagcaggttctccaccatgagctcctggccatcagagaggcctgcatcaagctggagaaggactatcagccagggatcacgttcatcgtggtgcagaagcggcaccacacacgcctcttctgcacagacaaaaacgagcgggttggaaagagtgggaacattcctgcaggcacaaccgtggacacgaagatcacccaccccactgagtttgacttctacctgtgcagtcacgccggcatccaggggacaagccgtccttcccactaccacgtgctttgggatgacaatcgtttttcttctgatgagctgcagattctgacctaccagctgtgtcacacctacgtgcgctgcacacgctctgtgtcaatacccgcgccagcttactatgctcacctggtggccttccgagccaggtaccacctggtggataaagaacatgacagcgctgaaggaagccatacctctgggcagagcaacgggcgagatcaccaagcgctggccaaggcggtccaggtccaccaggacacactgcgcaccatgtactttgcttgacctgttgtattgtttagcgattgtgtaccaagttggattcacacgagaccagctacactcagaccaacagatgcccagcccttctgtgacagccagcatcgaacatgagacgtctttggttttattagatcctccgttttccagaatgccttccgtcccagatgtcagacttggattttgagctgtaggcctgtatgagaccccagtgtaggaaacatggtttgccaaacctataagctgctcactgagagtcccgtttcctaaaaacaaaacaaaaaaacaaaacaacaacaaaatgtcctaaaaccagtctatgaactctcagggctttaaaacattttaatttatttggtcatccaatttacttgtttttaacacctgattctcaatgaaatcgatgggctccatctagctgtgaaggctctgagcatgaaagccacaccatttccattggggttttaaagcctggccctaagaagttgtcactaatgttgagttctaagggatgccatgcgccctgcagccccagggcgtatggctgctaggtctccacagtgtctctcgcggccactgcctgccctcgaggcctgaacaaaggcacagtggccaaggagatggtcacgtgtgtttacggcagtgacaagtccgagagattggcagacaagtgccattttgataaaaatttatttaaaaagagaaaaaaagacaatatactgacagtctaatcataagatttgtcctgtaggactgtgacatttattttccaaagtttctaaagaatacgggtctgtggtgataaatacagtacaatcctttttcactgttaatgtctttaatgtaagagaagaatatatgtatctggtttgcagtattaatgtggtaggtagatgctgtttccctttcgttgatgaggggcgcttctcgtgacctgcttcacatatcaggagctgtgtgaagcctggagacagtccacctcttgtggcttttagtgcttaagtagaggaatatgcaactggcttcacgtaccagcgatgccccctcctccctccccacccccagtgtggactgtgtagcctgtacctccggaaggacagtgcgcttgccagtaacctgccgtcctccctgcctcgtccatgtgtgtcgctcagccgatgaagcacaaatggaatttatttattcttccattgctgggaaacaagttcacgtaagagtgcacttctctcagtgtgcagttatggaaggtgggtttcataggatctatgcactgaagtggaaagagagctgcccatagcggctctgccagcatgggactggcaggtaggaatggactgtgcccgaggacctgactgtgggcaaggccagcagggaaggcacagactttctctgggtgttatttgcttctgggccccagtgtgggttttccagcccagagaccattgaactgagaaggggccactacgaatggctctgcggatggcagcagccacgtcagtgtgtgtgtccttgtggggctctctgtgcttgtcccgaagctgagcgagcatcgggctcactccgttccacatacgcgtgcgttcccggaaggagatgagccttctcttgtgtgctgctctgtgctctgtgggttttttctacccctgctgatgggcctcatcccccagctctgcgtcatttacctctgaccctgcggaggagggagggtgcccaccctctccccctgccgtggcacctcatgctagaggacacagtaccacctttgccccgttccccatcttctctggagctggtgggaagggcagacgcagttacctgggaagtcacaccctcagcaggtgtgtgtatccgtgtatgcatgtgggtgtcttactaatgacaatagtctcttcttgctgtgtctttagaaatcttttaaagtaacagacccccccagtctaagaagcactgggactgcctgctatcccattggcaagtggcaccttctcaaactgtttccaaaacgatataaaaacactcagttggcctaacatggtcaggctggggaactggttaaactagtgaacttttagaatctgaaattggattgttttcaaccattcttagaaccagtgtgtttctaaggtgtgtcttcagccccttgccatgggatcttagtcatgcaagtgagttttttagaatgcagattctcaggcctgctgccagcttcttggatctggcactgtgtttgaggccacccctcaacccccaccgtggctctgtaggctttctgaggccgtccccccttatgccagggggacaggaaggaacccctatcagagctcacacctaggaacacttgtgggctggggcaaaaaaatcttgagctgggagttttgttttgatcaccttgaaggataggttttctttctgatgggccaaagtactggacgagaagtgttttctgtaggagcccacgcttacttgtgacacttttaataggaaatgtatccccagaccaaatgtccctaattgagttagatgcacaccatccacatgtctgatggtgcagagcttataaatggctatagttccaatttctcaggtaaataattgttttccccaatttctgccctccccttattaatattagtttgagacagtgtgagacctcagagtgcggtagcagctccggccatcttctgcaggagccagctttttgtgtgtatctgtacccaagactggtgacaggtgccattttctcctgaggtgatacctggccaagtttgacgactgcccacttgctagctgtgttcccaaccccactgttaagtaaggtgtgccttgctttaagcaaactgaatgtgattgtgttgtgtgtgctctgtatccatttggaaggaaaactaggatgtgcctgtctctttaagagaggctagccaattagcctctcatggtgggactctcctagtacactgtaagatactcttaaaaaacccatcgtgacatccatccctttaccactgtgtgcaccatgcagcaggtccctccctccccatgctcatgaagcaatgcaaaactctagagagacatcgaggccccattccatagatttagccctagtgatactagcaaaactcccaccctgtcactgcgtgttttaagcccagattctcctagtccccatcgagtctgaaaccgagcacgcctgtacttcttgtcaggggctgttgggttttggcttccttctcccatttggggaagtcctcacatgcacacttgataccactttgggtctgctctgccttctccagatttggcctcttggccactcctcacacccacccgcttgctggcctccaggccacagggcactgccagtgaggagactgctagctccgtgctgtctgcagctggcccaacttctgtattcctaatgtttacctgttactgagcgcttgatagaaagacgggcccctgcagcgggcttgggcgggtttggttttttggttttggttttccattgtcttgttcttgtgttattttattggttttaaatgcaaatgttgctatttatttttttctctctcctgctctggtttgactaagctgatctggctatctcaatgcatgtggtacctgatggatggatatggtagagattatttcccccgccttttataactggcccggtatttaccttcaggcttgctaatgctttatttttggaagccacagatgtagtttttctggatgaattgcttttcctatagatgcagcggtatgcttttgcattgatctgcagggtgatttgaattttatttttacaagcagtttttcaatcaaattctatatttgatacaatgtgttaaggctagaccagcccgaagtcatgcagctggggacccctgagtgtccaggaggccttagggctgggtggcctctcttggtagtccctgtggtggtagcactggtcacaggaacctgcagggtcttcattatggccctgacctcgtagattgttacaaggattttttttcatgggcattttgctacacagacagtggacaatcccggtggccccagacaagccataagcaacctttctgtgacctctccctgactcatctctcacacccatgataaaaggaatgtgccctgagtagaagctacacttccttggtgttcatctgcctcacttgtgaatgcagatattttgtttgttttaagcccttccctgcagtaaccatgctggctggctctcacataggcagagcacacgtgactcttgtcatgagcgccccgttgcaggcatgccgactcctgtaagttgcactgatctctcgacagtttcctttattgcgtccaactccccatctgctgtactcatttgaagtgattgtaaacggattcacagtggcaagagtgacgttgatgtgggacattgcctcacttctgccatcccaacacacatttcagtattacgtgctcgagtgtgcgggctgggctcttactctctcaagcattgtgggctagccttgtctcaacactctgacaagaagttctccctctctatacaggacagcatgctctttgagacctgaaggcttgaatgtaaacaggttagttagaagtctttgtggcgctttggtctgtttagttttcttgtgatctgcaaggccccccaaaagtatgtccttctagttccgtgtggcctttgtcagcgtggacagcatatgaatagcccagtcagtgttaacaggccattgctacattctttggccagcccctcaacttaaagttgtgaggtcactgctgtgtcagactgtcatttgtggtccatccatgggagacctaaagcctggtgcagccctttatgccttgtgaccctgctgggacctaagtgtacatgatctgtttagccccacatggactgtctgtagtcagggtgcccagagtctgaaacaaaaggaattattacacttaaaccgcgcagggggacgacacacagacagacagtgccattgcagacattgcagagccctccctcaccttgtgtctttggatttgttcagccattttatttgtctcaagttgaatgtaccggcttagccaaatcactacagaaggtggtttctttaaaccttttagacagatgcataaaagctacctctgacttctcatagatttgtgtttgctctgaagcatcgctatccacactgaatatagccaaaatatcgcctgaataaaccgagttacgaactcctctgttcacttctggcttgaaaatgtgtgagtgccatactgtgatctgaggcggtggcttctctgctgccactgacccagggactcctcagcaccacccagctacaagatcctagcgtctgagaggctggtagacgggcttctctgcatggggaacatgcaccctccaggctggtgggcgtgactgcgcaaggccacgtgcggctgagcctggaggtggtctgttcctgcctggttttgctttcctatttaatagtgtaagaaggcatctttacccctgctttgcttctgaatggattgaaagtggctttcctgctctctcctccctttttgtacactataaactcataaaggtgcttcaacaccgactcttgtgcagataatgtagttaagcagttgcatggattcagatagtgcaggcacagctgaccttgggaccctggtgaaagtgaaggactgaaagccctgagctccatttggagggagcagtgggctctgcttgactaggtccctttagcgttggcagaacagagatttgtcatggggacccgccacctctgaccaagctgtcctgtggctgtccactttgctgtccaggaggtcatcctcttacatcatggctccacctgcattgccttggcctctccacctaaagtttccttggaaagtcagcataagatcccagattcccctgtttagcttgagggacagatggacagtgtcatgaaggcaggtgcctggggattgggctgggcttaggggagctcttctaaaggttgtctctgtgccctccccaacctcccccacatacaccccccattgtattgttttggggggtgtcatcttccattcttttgacttggacagctcagtacccttaagagccctcacacatttctctgtgtagagaacctgaggcgtggagggtggtggggtgtctgcaacacccctgacctgcaccccaggtttcttaaatcctctgacttggctggaatttgaaaatccagggaagcacagggtgctagatatgttacacttagggtcacacccaggtgccgtggtgtaagccacagccctcagggcaccagcacagaggcagccagcctccccactcgtgacatttgggaaggataccaaacaagccagagccctggctgctgcagtattcagctaacacttccttttcctggttgaagggagaacactatttgaaaccttctaatgccctggtggttctagttcctctgttcctgagggctaaaaggttgaatgagctcctgttttgcttagagctgcctttgagtccatttaaaggtgaagcatgggactgtatcctcttccctgagtcaccagcaagtaggtgtggagacccttctcattcagttctttctgcatcttcaagcgccccaacatcagtgggatcacaagagcacccacaccagccatcagcggagtcaagtatacatatggggacagaaattggcaaatttacaggttgtaatggccactccagcttgtgacagggaaggccctccatcctgcacagcaggtggccttggtcctacctccaggcactggctttactatctggacacctagtctcacacttgagagccttgaaagtctgttcttggtgtccttctagaatcatgctgggacaggtcattagttgaccctgcccagaagctctgtcagccctcagctctttcttgcaaactgtgatgccaccttgtagcctatggctgtggagccccgtcctgggttctttgtgccctgaaatacaggtgcacctctgctgggggttggttgggcactggcaaaggctacttgctggtcttgtgttctctgcccctcagcaagactgtctgttgtagtggaagtaggtttagagggatttggaatcatgtctttgtgaatcgagtgtgacgtcatcaggggtaaggtgctacttggtcctaatgttttggaatgcttttccgtcttgttactccattgttactctctgttctatgacactggggagactgctcacttaggtgtggtgtcacataggactccagctttgatgtgctgtgcgggtggtgtgattatcatctctgaccttctcaagccaggggtggtacccttccctagcttagtctaattaaatctttcctccctgtcaagtgattgctttgggtggttttaacaggagtagtccagtctggttattctattttcttaataacatagaaaaggcccgtgcagcactagctgcagacagataacatatttaacaattttggttcatcttcaaagccaaatagacctatgtgattaaactccaagagggtacaattcagcattaaattaaaatttgagtcatgaatttgagagggaatttcagtatagttgataaagttatgaattaatgttttataattgtagtggcaagtgagtatttataaaatttataagagaataattgtaagtttctgtacaacaatttggctactgcctcataaaaacaggaagagaccatagccctgaatctgactctcttatctcccacatactttggattatctgcctaatatgtatttgaggggttttaacccttggttttatcaaattttctagttttattttatttttataaaataattgaaaaagaaccaaaaaggaatccagaagttccccagcggctcctcccccagtcttaattccccctacacacacattcaaatgttttagaagacattttgaatcaaaatgtattccatccatttaacgtttgctactttctgagaagtggagtggctacaagggcctgtttcaggtggtactctgtatgtcatggacatgtttgtacctgtacagtggatctgtgtgacgacgtcttgtgcttgcggtttagaaaccacgcagtgctgttttgtaaattgacagtttctgtgtaaactattatttatatcccttggcccttctgtataatttttcatttgctacatggattgtataattaattataaaattatagtacctgctaaacccaattctgaggcttcatgtcattgtctttggtttgataccagtctggatcgggaggctgcccaggccttgcgcaataccagtagtgatgtcacttaaagttaagccttaatcagataatgaatttgtgcatttcagagtatgcaaaaaaaaaaaaaaaa

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