LOCUS       XM_010901057            5485 bp    mRNA    linear   VRT 11-MAY-2020
DEFINITION  PREDICTED: Esox lucius argonaute RISC component 1 (ago1),
            transcript variant X4, mRNA.
ACCESSION   XM_010901057
VERSION     XM_010901057.5
DBLINK      BioProject: PRJNA629749
KEYWORDS    RefSeq.
SOURCE      Esox lucius (northern pike)
  ORGANISM  Esox lucius
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Esociformes; Esocidae; Esox.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_047588.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On May 11, 2020 this sequence version replaced XM_010901057.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Esox lucius Annotation Release 104
            Annotation Version          :: 104
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5485
                     /organism="Esox lucius"
                     /mol_type="mRNA"
                     /isolate="fEsoLuc1"
                     /db_xref="taxon:8010"
                     /chromosome="20"
                     /tissue_type="liver, spleen"
                     /dev_stage="adult"
                     /country="Czech Republic: Jihlava River, Danube basin"
                     /lat_lon="49.218 N 16.717 E"
                     /collection_date="29-Nov-2018"
                     /collected_by="Martin Reichard"
     gene            1..5485
                     /gene="ago1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 13 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:105028369"
     CDS             440..3055
                     /gene="ago1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X4"
                     /protein_id="XP_010899359.1"
                     /db_xref="GeneID:105028369"
                     /translation="

MEPGPSGAVPMGPFPPPLQQVFQAPRRPGMGTVGKPIKLLANYFEVEIPKMDVFHYEVDIKPDKCPRRVNREVVEYMVQHFKPQLFGDRKPVYDGKKNIYTVLALPIGSEKVDFEVTIPGEGKDRIFKVSIRFLATVSWRLLQETLVSGRLQVPLDSVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKTLTDSQRVRFTKEIKGGPLNSDRWALPGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNANFNLDPYIQEFGIKVKDDMAEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKSERIGKSGNIPAGTTVDTSITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSSGEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA"

     misc_feature    446..3049
                     /gene="ago1"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:215631"
     misc_feature    1646..2923
                     /gene="ago1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2057..2059,2069..2071,2105..2116,2123..2125,
                     2147..2149,2156..2158,2168..2170,2180..2182)
                     /gene="ago1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2261..2263,2267..2269,2477..2479,2891..2893)
                     /gene="ago1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

aatgcgacatcaatcaaaatggaagaaggggttccagaattcgtgtagaggggttggcccttttttgttcggctggagaatcctgcttgaacggggagcaggaacataacagaccgcccagaaagcatcgcgccacggacgatcctacatatcaggccgggcaacgggcgttcaacccaaaggagagtagacagagacacggtacggcactagagccgttcagacgtcggttctggactcataagatagctaggtagctcttgttgttacaactctgggggtactggaaggggtagggggcggaggtctagcgagtacggagaagcctacacgccgagaggagggggctggaagtctgcaacgcttccagcctgaaggggccggcgctgtggccatagaaccctggactgtctagagcccgcgcggctaagtggatgggatggagccgggaccgtctggcgctgtgcccatggggcccttccccccacccctgcagcaggtgttccaggcgccccgccggccaggcatgggcacggtgggcaaaccaatcaagctgctggccaactactttgaggtggagatccccaagatggatgtcttccactacgaggtggacatcaagcccgacaagtgcccccgacgggttaacagggaagtggtggaatacatggtgcaacacttcaagccccagctctttggcgacaggaaaccagtgtatgatggcaagaagaacatctatacggtgctagcacttcctatcggaagtgagaaggtggactttgaggtgaccattcccggggaggggaaggatcgtatcttcaaggtgtctatccgatttctggccacggtgtcatggcgtctgctccaagaaacgctggtcagcgggcgcctgcaggtacccctggactcggtccaggcgctggatgtggccatgcgccacctggcctccatgaggtacactcctgtaggacgatcgtttttctcccctccagaaggctactaccaccctctgggaggggggagggaggtgtggtttgggttccaccagtcggtacgacccgccatgtggaagatgatgctcaacattgacgtgtctgccacggccttttacaaagcccagccagtgatcgagttcatgtgtgaggtcctggacatccgcaacatagacgagcagcccaaaaccctgaccgactcgcagagggtccgcttcaccaaggagatcaaaggtgggccgttgaacagtgatcggtgggcgttgccaggtctgaaggtggaggtgactcactgcggtcagatgaagaggaagtaccgggtctgcaacgtgacccggcgtcccgccagccaccagacgtttcccttgcagcttgagagtggccagactgtagaatgtacagtagcccagtacttcaagcagaagtacaatctccagctgaaatacccccacctcccctgccttcaggtgggccaggagcagaagcacacctacctacccctggaggtgtgtaacatcgtagcaggacaacggtgcatcaagaagctgaccgataatcagacgtccactatgatcaaagccacggctcgttctgcaccggacagacaggaggagatcagcagactgatgaagaatgccaactttaacctggacccgtacattcaggagtttgggatcaaggtgaaggatgacatggcggaggtgaccgggagagtgctgcccgcccccatccttcagtacggaggacggaaccgggccatcgcaactcccaaccagggggtgtgggacatgaggggcaaacaattttacaacggcattgagatcaaagtgtgggccatcgcttgcttcgccccccagaagcagtgtcgggaggaggtgctcaagaacttcaccgaccagctgcgtaagatctccaaggatgctgggatgcccatccagggccagccatgtttctgtaaatacgcccagggtgccgacagtgtggagcccatgttcaggcacctgaagaacacctactccggactccagctcatcatcgtcattctgcctggaaagaccccagtctatgcggaggtgaagagggttggagacaccctccttggaatggccactcagtgtgtccaggtgaagaacgttgtgaagacgtccccccaaaccctgtccaacctctgcctgaagatcaacgtcaagctggggggaatcaacaacattctggtgcctcaccaacggtcagcagtgttccagcagcctgtcatcttccttggggctgatgttacacaccccccggctggagacgggaagaagccctccatcactgctgtggtgggcagtatggacgcccaccccagcaggtactgtgccacagtgagggttcagaggcccaggcaggagatcatcgaggacctgtcttacatggtgcgagagctgctgatccagttctacaagtccacccgctttaagcccaccaggatcatcttctacagggacggagtgccagagggtcagctgccacagatcctccactatgagcttttggctatcagggatgcatgcatcaagctggagaaggactaccagcctggcatcacctacattgtggtccagaagcgtcaccatacccgcctcttctgtgccgacaagtcagagagaattgggaagagtgggaacattcctgcagggaccacggtggacaccagcattactcacccatttgagtttgacttctacctgtgcagtcacgcagggatacaggggacaagtcgtccttcgcattactacgttctttgggacgacaatcgtttcaccgctgacgagctgcaaatcctcacctaccagctgtgccacacctacgtgcgctgtacccgctccgtctcaatccccgcgccagcttactacgcccgcctcgtggccttccgtgctcgctaccatctggtggacaaggagcacgacagtagtggggagggcagccatgtctctggccagagcaacggtcgcgacccccaggctctggccaaggccgtgcagattcaccacgacaccctaaggaccatgtacttcgcctgagcaccacaccgccaccatgactgcccttaacacccagcgggcggccctctggtgaggggcttaggagtccacttgatgcctcactcctcagcttctcacaccttcggccaccgcagcaccagaaccatacttcgctcacctgaacgacccaggcagactgcagcgtcctgcactcagttattgttaatattattatttttgtttactttgccatgacagtgctctttttatgttgacttttaaaacaaatgggtattattgcagtgtatgcaaccttccacactgctatggaagtatgcaatatggaaggaaggaaaacgggctttgagacgccctgggacttcagactgccacaatgctgcctcttactggtccgcaccacggacaacagtgttctgtttccgagcctctggtacaactgggggtcacggggggtcccggagggcaacagaaagaacacacacttcttatctttttaaccttttatcatgacctctgttcttatgttgccgttgtgtttttttgttttatttttgccttaaggcacacggcgtgaggtatggtgcattagcacttagcagttagcatgtagacaacaccgccccaccctgcacctaatatgaagtttatctgtacgcgtgaggctagccctcggctcttggtagtagcagaatgaggagggcaggtacaacttatgctacacgtgtgcaggacacgtagtcctcccacatgatacctgtgcaggttggggaggtccctcttgcctagagaattatctaatagagagaggcaaatgtagacgttagatggaccattgcatcgagtgtattaaatatacttgcacctcgtgcacataagccagcattctgaatgagcaaatgggatgccaaccaacagaacaggggcacttacataaacacaatggggggggggttcattcccccacgccacacacacacacacacttagtaacataattcatgttcttacacataaaacctctctaagcttgctgaacctttcgagtaacagtagcaatacaaggtagcagcagaccgacgtgggccagagagcgccatggtgttcgtctctcaccttgggcactcagccttggctgtaccgcctccagcacattctgtcttcacagtccgccgtgttgtcagtggagacgacgtccacacttaacgcaccacgatgtggcgtacacctacacacacacacacactgatactgtcagaacacttagccccgctcccttattttgtacatagctcctcttcctacctaaaggcattgaccacggcaactgggacacaagcgcgctcatgcctcctcaaccgctctgtcgtgctcgtacttaagagagtaccgagccgcctccacacatgtccttgccccattgaaagcccccacataaacacttgcgccctccttctgacacccccatcctctttcctaggcatacccttcatcgttggccactcccctcagcctagtggacaatccccattggtgcgctgtgtgcatggacaacacagatacggggttttctacgaaggttatgggggtttctcccttaatatgtcctgccttcacttctggtcactttctggctttatgatacgcatgcaacattatttttttattattgtgactggatattctgagccaccttatttcagttttcctagtgataggagcttattacgctcacttcttctgcctgtcagtcatagcttcaattgtgtaaatggcgtttctgaaaggctgctttttgtgttctgtattgtagtgagtagtgtcagagtgtatcctcaagggggtgctacctttcccttgttgccctcaaacgcctcaaatcatgtctgttgggttgtagagctcctttttgtcggaagcgatcaacgatagagattcaatgatatgccagattttttttgacacatgttaatgaacttgcgtaatcaaaatgcctttgtacaccattttactgaccccatgtgtccaaggtgatttgtatataacctataatgtattttggctcatcaatgtagcagggcctttgcagttggggttagtctccctcacccaccccctctgttaaaatgtcaggctcgggaagcccagttccactgatccagatacagttcgtaacttaatttactgaagccacaaagcaccttgcaaccggggagagcaacaatatggaattaccctggaaaaagcatcatgatgagaaatccgctccacccagcctcactgactaagcaatataaaagccactgatcaggaacagtccttgtcatagcacttcccaatagattgatgaagggacatggaataatgttattttggctctgtatgatgtaagagtatggggctctgttggggagggctattttttaaagaaaataaatttgttttttatta

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