LOCUS       XM_003765340            7566 bp    mRNA    linear   MAM 31-DEC-2019
DEFINITION  PREDICTED: Sarcophilus harrisii argonaute RISC component 1 (AGO1),
            mRNA.
ACCESSION   XM_003765340
VERSION     XM_003765340.4
DBLINK      BioProject: PRJNA596784
KEYWORDS    RefSeq.
SOURCE      Sarcophilus harrisii (Tasmanian devil)
  ORGANISM  Sarcophilus harrisii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045428.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 31, 2019 this sequence version replaced XM_003765340.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Sarcophilus harrisii Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7566
                     /organism="Sarcophilus harrisii"
                     /mol_type="mRNA"
                     /db_xref="taxon:9305"
                     /chromosome="3"
                     /cell_line="91H"
     gene            1..7566
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 9 ESTs, 38 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 40 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:100920633"
     CDS             144..2717
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1"
                     /protein_id="XP_003765388.1"
                     /db_xref="GeneID:100920633"
                     /translation="

MEAGPSGAAAGTYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWMAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVRDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    243..635
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    663..815
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    816..1178
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(972..974,1017..1019,1059..1061,1071..1073,
                     1125..1127,1146..1148,1152..1154)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1311..2588
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1722..1724,1734..1736,1770..1781,1788..1790,
                     1812..1814,1821..1823,1833..1835,1845..1847)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1926..1928,1932..1934,2142..2144,2556..2558)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gcgggcgggagctgccggggtgggggggggagcggagcccggcccgggagcgggaaccacgggagcgaactggggcccgggcccccccacgccgtgcaccagactcactcccggctgcctgatctaacacacgggtatatgggatggaagcgggaccctcgggagcagctgcaggcacctacctgcctcccctgcagcaggtgttccaggccccgagacggcctgggataggcactgtaggcaagcccatcaagctcttggccaactatttcgaggtagatatccccaagatcgacgtctaccactatgaggtggacatcaaaccggacaagtgtccccgcagagtcaacagagaggtggtggaatatatggttcagcacttcaagccacagatttttggtgacaggaaacctgtgtatgatgggaagaagaacatctacacagttactgccttgcctattggcaatgaaagggtggactttgaggtgacaatccctggtgaagggaaggatcggatcttcaaggtttccatcaaatggatggccattgtcagctggcgtatgcttcacgaagccctggtcagtggacagattcctgtccctctggaatctgttcaggccctggatgtggccatgagacacctggcatctatgaggtacacccctgttggccgttccttcttctctccccctgagggatactaccaccctctggggggtgggcgtgaagtctggttcggctttcaccagtctgttcggccagccatgtggaaaatgatgttgaatattgatgtttcggccacggctttctacaaagcacagccagtcattgagttcatgtgtgaggtgcttgacataaggaacattgatgagcagcccaagccactaactgattcccagagagttcgattcaccaaggagatcaaaggactgaaggtggaggtgacccattgtgggcagatgaagaggaaataccgagtgtgtaacgtcacccgccggcctgccagccatcagacgtttcccttgcagttggagagtggacagacagtagagtgcactgtggcccagtatttcaagcagaagtacaacctacaacttaagtatccccacctgccatgcctgcaggtcggccaggaacaaaaacatacctacctgcctctggaggtctgtaacattgtggctggacagcgctgtatcaagaagctgacagacaatcagacttcaaccatgatcaaagctactgcaaggtcagccccagacaggcaggaggagatcagccgcctgatgaagaatgccagctacaatctagacccctacatacaggagtttgggatcaaagtcagagatgacatgacagaagtgactggccgagtactcccagctccaatcctgcagtatggtggacggaaccgagccatcgccacacccaaccaaggtgtatgggacatgcgaggaaagcagttctacaatggaattgagatcaaagtctgggccattgcctgctttgcaccccaaaagcagtgtcgggaagaggtgctgaagaacttcacagaccagctccgtaagatttccaaggatgcagggatgcccatccagggccagccttgtttctgcaaatacgcgcagggtgcagacagcgtggagcccatgttccggcatctcaagaacacctactcgggactgcaactcatcattgttatcctgcccgggaagacgcctgtgtatgcggaggtaaagcgagtaggagacacgctgttaggcatggccacacagtgcgtgcaagtcaagaatgtggtgaagacatctccccagactctgtccaatctctgtctcaaaatcaacgtcaagcttgggggaatcaacaacatcctagtccctcatcagcgatcagctgtctttcagcagcctgtcatattcctgggagcagatgtcactcatcctccagccggggatgggaaaaagccctctatcacagctgtggttggcagcatggatgctcacccaagtcgttactgtgcaacagttcgagtccaacgacccagacaggaaatcattgaagatctgtcttacatggttcgggagttgctcatacagttctacaaatccacccgatttaaacctacccgcattatcttctaccgggatggtgtccctgaaggtcaactcccacagatcctccactatgagctgctggccatccgcgatgcctgcataaagttggagaaggactatcaaccagggatcacatatatcgtggtccagaagcgccaccacactcgccttttctgtgccgacaagaatgaaagaattgggaagagtggaaatatcccagcaggcaccactgtggacaccaacatcactcacccatttgaatttgacttctatctgtgtagccatgcgggcatccagggcacaagccgaccatcccattactatgtcctctgggatgacaaccgtttcacagcagatgagctgcagatcttgacctaccagctatgtcacacttacgtgcgctgtacacgctccgtctccatcccagcacctgcctactatgctcgcctcgtggctttccgggcacgctatcacttggtggacaaagagcatgacagcggtgaggggagccacatatcgggacagagcaatgggcgagatccccaggccctggccaaggctgtgcaggttcaccaggacactttgcgcaccatgtactttgcttgaaaggcagaacgctgttacctcactggaaagaagaaagctttcagagcccaaggagccatacagatggaaggaatcccaaggaagaggagtccaggggagtgggaggggaatgggggcaggctggggggagggggttgggggaaggagagcttgtttccccactgcagagcagaagctgcatcactagggggtgggggatggggggcagggctggcaaagagggaccaccagccagagacccctgactcttcccttgctctgccacatctgacccgaccccagtggaccaagagagaggcagcatcgtcgctcacaggtgcccattttaaaatgcaatactaaagacttgtgactgggagggctccataaggtcggctctacagctgcggctcgagggacagaagctggtaggtttgggttcacttcttttagagggaaaagtgttggcttggaaaagagggtgggaggaggaagagggaaggatttttaggagccttaatcaaaaaggtatagattcatttaagaaaaaaaaaatcccaaaccaatattttaggatagtagagtttttaatgggtttgaaatccagtttgtagggaaattctaccaccagtagttttggttgctcctcccccagctgtcacccctcccctctgcggcacaccttccgtggcaccttcctctctccccttccccatcagatgtaaggcactatggcacttagtttgaattgacacagccctgtcttccttctgccccactggtgggtgaccagtgccttcactgtaatgctgcagaactgcaacctttttgtaccttttttttttgtgtgtgtgggagggggagaagggggatatgggaagaaggggagaaataccccaagtctcagaggcctcctgtaggtgacgctgccagctgtctgcatcagaaggaattgactatgacattcacagagtgaacccattgctttgagatcacaacctcaagatggttaaaatccattgaagacatttgcactttcagacatgacaagtttcttagctgctgagataactgacccttgccctcccctcactcctacccctctgtccccagattcccagagcgttatttcaatggcatcctttcctccatgacagttgagtctcccgtgtttcaacatttctttgctgggctatcttagaacaaaagatacttaggtctaaaagaagaaaaaaagagaaaactaaatgttatttttatacagtatcttgagtctgttgccaaaacttgcaggtgactctcatgtcctctgagtttacatcccagacacactgagccgtccgtctgtctgtccatagaagggttgtgcacctgggtcattgtttctgcccagttggcagggggtgaagttggagccctcctatttcttggttccctcccccactctgtgcattatccaccattcccttgcgccccttcccaagaggatcctgctgtctcatctattcttagtcggaactcaggctttccgactccagcatggcctataacacactttttgatagcttctgctgcttgctttcgctgctgtttacacaaaatacttttagttctgctcgcaaggggcagatggggaagcatatgcatgtgtacatataggcatccctctttctgcagtcagtgaaggggtctgattagggtaaagtgcgagggggtatagttagtcggtcacttgggggagaacaagagccccagactgtctaaggcctctttaggttactgggtgcccagggtatcagtggttaggccccttcctctgacatgggtaagtatagggactgcttatttatgcccagctggtgaggacaaggaacctcagctcattgtgggaatttctctttgcgctttaagggattagacatgaggcagcctagtctgtcatctcttctactgggctttagcttggttgttttgcaaccactgaccttgagggccacacccttagaagaagcccatgtgggaagccttggccgttaggcctagtggctggtaaagcagacacaggactggagactggcttgaaaccaaatctctgtccttgtctgctcagggaaaggtgggcaggtgttggaaaatggctcttcccccttcccagcagaagagttgccagaccatgatttgctatgcaaaataatctaccccaatctctatttttgttgaccatattgttcaaagatatcagcaaaatttagcacaaacaatagctgtggaatagggcattgggacagtttggtaattccttccattccttccttccttcccttccttcctagccagtagtatcgcctaccctgccgtccatgggctagatagctgggaaagccagtggctctcccctagttgtgggtggcagggtggggaggggctctgggagggggtgagctcacctaggagcctacattccttacacaagtgcctatattgtgatgtcaacactctgcccgcctctgtccatttccatatccccgcctctagtttgtgtccattcatacctctgggtggggctccagccttttgaagctcccccaggaccagtggctttgcatgttttctccgcatgtgtcttgggcttggggttcagggcagttttcctgggagggtacaatcattcaccagcatttttatccatgcccgtggcaggtggcagccacagggcccggtttgtgttcctccttttctctctctgcctccctcctgttgaattttgagctggggtctgaattgcttttttagaaatgttggcattacatatgccatttgtaaaataaataaatgaaagtgcgaggagcagcttgggcattcgtaaaaaaaaaaaaaaaaaaaaaccaacacaaaaaaaaacagctttgttgctcttgtgatttttttttttttttttttttagcctttgagacttgaaatataaacttgatcttagaatttgcacttgtgtgtgaggtgccgtgtgcaggatgagaaggtggtcctggcatcaagctctcatctctgtgggattgcttgtccagatgttgggggtacccagagtgccccggccaacctcttaactgtctattgcttcccccacttttctcagtacccccattctgcttctatgcctttttgagatcaagcctctgcagagccccagtgtcaatagttaagcctattgtgaagccattactcctttgcttctgagcacctggaattccattttttctataggtctgattcataatgtagtgcccatctggcatctggtgctgcatgagtgtccgtgtgagcctcttgctgtgtctgtcccaaggcctcagctgatgcagaatcaacaggcatgccaagctggggtaactacaggaggctttgcttctccttaggcccatcctaaccaccacaaggtgctattcctgctgtaatactgagcaccctgtatgcttctggtcctggttaccccagcagctgcctctctttctgggccacatctctgagtagcctcctttaaggaggcctggaattcaatgccttaggtggccaaatattctaggctgggtaggctaagggagcagagcgaactaattcttcttgccttctgttccttcatgggtgcatggggtcagattggaggaaagatctgtcccttccacagtttggaatagtcttgaggtatcaagccagtgattaaacagaaatggcaagaaatattcccgagtactgcaaaggccattcaggttggattgaattgattcttgattgacatgccagtcgggcatcccctttaatctaggatcaatgccacaggaccccctaggtccgagaagcagtgctggtggtggggatgagacctaggcaggacaggcagcttgggaagtcctttttctccttgcctgggtgaattgttatgtacaaaactgttggaggctttttctggagctgagacctggcagggcgggccatttggcaatagaatgtagggagagctacctccatgtagcaaaaaaagggggctttggaactagcatccaagggtagttgtgctttatttattaacctggtatttgtgccaggatgaatactcggttaccttcttctcccaaaagcttggacatcgtggatgtgccaagtctgtgaagggcaacccaaggcattctgcatcctctctgctctgtctggccctcagcagctggggaggtgctcttatcttttaatctcttcaatttttaaggacttgtcttctccctgggctgatgcaggacccaaaatggtattctacagccattccactctcttcagactctgagcttcaggctgctgcagagggagagggaggttggggacacgttactggagcactcaaggcttgtgaagaagcactaaaaaggggcagggttcatctcctttttgaaaatgaatcttcaaaacattgtgcaaataaagagaatctgttgagtctaatgacagtccaatggctgaacagcaataagaaaacgctggaggacattgttttgtgtacgtatgtggtgttgttgcacttagcagaggtatggtggacagagggttcggagcactcctgggatttagtttcagttcagtttccaaactttcacacctccctgagcccagtgaaggcggagctggccttggggccccacacccagagtccttgtttgcttttggttttctctttgacctgtgttagtgtcctgcttctgactgtatgctggatggtccttttgtgaaactgcccaagcggttgtaacggacatttatttctgaaacaagcagccgcatgatattgtgttttataaagataacaatggcttatgttttaaaagtg

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