LOCUS       XM_073929033            6185 bp    mRNA    linear   VRT 12-MAY-2025
DEFINITION  PREDICTED: Danio rerio nucleoporin 205 (nup205), transcript variant
            X2, mRNA.
ACCESSION   XM_073929033
VERSION     XM_073929033.1
DBLINK      BioProject: PRJNA1248012
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_133193) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_049306965.1-RS_2025_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/11/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6185
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /isolation_source="Zebrafish international resource
                     center"
                     /db_xref="taxon:7955"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="Fibroblasts and whole tissue"
                     /dev_stage="adult"
                     /ecotype="United States"
                     /geo_loc_name="USA"
                     /collection_date="2022-07-19"
                     /collected_by="National Human Genome Research Institute"
                     /genotype="Double heterozygous"
     gene            1..6185
                     /gene="nup205"
                     /gene_synonym="zgc:111802"
                     /note="nucleoporin 205; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 23 ESTs, 610 long
                     SRA reads, 2 Proteins"
                     /db_xref="GeneID:445382"
                     /db_xref="ZFIN:ZDB-GENE-040715-8"
     misc_feature    1
                     /gene="nup205"
                     /gene_synonym="zgc:111802"
                     /experiment="COORDINATES: cap analysis [ECO:0007248]"
                     /note="transcription start site"
     CDS             16..6009
                     /gene="nup205"
                     /gene_synonym="zgc:111802"
                     /codon_start=1
                     /product="nuclear pore complex protein Nup205 isoform X2"
                     /protein_id="XP_073785134.1"
                     /db_xref="GeneID:445382"
                     /db_xref="ZFIN:ZDB-GENE-040715-8"
                     /translation="

MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLISDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAAVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRGQLSLKLQDYFQMLLNDMVSYQIALCADPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS"

     misc_feature    508..5004
                     /gene="nup205"
                     /gene_synonym="zgc:111802"
                     /note="Nuclear pore complex scaffold, nucleoporins
                     186/192/205; Region: Nup192; pfam11894"
                     /db_xref="CDD:463387"
     polyA_site      6185
                     /gene="nup205"
                     /gene_synonym="zgc:111802"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

actcacgcttcagacatggcgacgcagatggcggtaaattcaggagccagtctgtgggggccgctgaaggagctctgggaggctgtggaaggggccatttggagacgtcaaccagaaagtgttcatcttttagatctgcagttgaagaaacacaaaccctacttcctcaacctctttaaaaacccaccgaagagtgcagaacagagagagaaggttcggaaagccagtacagaaggcattgctatccagggtcagcagggagcaagactacttcctgagcagctcatctctgaagccttcatccttagtgacctttttgaccttggagaactagccgccctcgagctgctgctggcaggagagcatcagcaacctcatttccccggcctgacccgaggcctggtagctgtgctcctttactgggatggtaaacgctgcgtggccaactctctccgctcacttatccagtccagacatgggaagactttcactcttgacttgagtcctgaattggtaaatctcaccacacggttcacagatgagctgatggcccagggtttgaccaagcaaatactgaacctgatctctgacgtcagcgtgacccgtgagtttgagaggctgcagaaagagcgtggccttggcaatgagaaacacaggaaagaggtatctgacctcatcaaagagtgccgacagtctctggcagagtgtttgtttgcgtgggcatgccagtcaccgctaggcaaagatgacacgctggctctcattgggcatttggagatggtgaccgctgaagctgacggctctttggatagtgtcaaccttgctttggtcatggcattgctctattccctggatgttagttttctggagcaaggaacagaagatagagaagacctgctccaggctttgcctctgttgacggagaaacagtacgtggcagcagtgcacagtcggctggtagagggtcaaggctggaagcttccaggactgcaggcagcggtgcagctggcctgggcgctgtctctgagggccctttcacaacttccacagggtgcagctttagtggagttcactgaagcagatgaggctctggcagaccaggcgctgttgggaggcgtcttcctctttctgacggagggcgtcctgggaagtgatggtttcagccaagaagaattttacacccggcggctgcattctctgattactgatttcctggcactcatgccaatgaaggtgaaacagttgcgcaaccgtgccgatgaagatgctcgtctgatccacatggctctgcagatgggcagcgagccgccatcatctcttcgcaaggacctggaccacctcatgatccttattggagaattttacagcaaagatccatttgaacttgagctggctttagagttttggtgtccatcagagtctcttcagcacacttcactcactggatcttttcttggagtacctctccaaagacccccacataaacaggtggttctctccaagtttgtgcgtcagatgggtgatctgcttcctgcgactctttacatcccatacctgcgaatgctgaaaggacttgcaaatggccctcagtgctcccactactgcttcagtttgcttaaaactaacggcgctccacacggagagaaccggcaggctggagtgtcaggcagtcttgtgtcatgggaacactttttccactctctcatgctgtaccatgaaaacctgcgacgagacgtgcccagtgccgacagcacacaataccgtcatctaccaatcagaggcatcactcagagagagctggaaggtctcactgcattcctccagctgctcaccacgatcatcacctggagtgagaatgcacgtctggctctttgtgagcaccctcagtggacgcctgtggtggtgatgctgggtttgctgcagtgtagtgttcagcccgtcctcaaagctcaagtccttcatgttctcgctgcttttggcaaatctcccgagattgcagcctccctctggcagtctctggagtacacacagatcctacaaacagtgaaaatccctggtcagagacaggctgctgggatcgaggtggagctgaatgagattgaatcgagctgtgaggagtatccactcacacgggccttttgtcatctgatcagtactctggtggagagcgcacttccagtcaatcttggagcaggactgcgagctcccggctttcaaccttatcttgacttcctgcgtgactctgtgtttctggccttccccacgcgagcctaccgtcgctcagcagaaaagtgggaggtagctgaagcagtgctagaggtttttcacaaacttctgcgagaatatgagccccagccttcagacttcctgccggagatggtggaacttcaaggagagcaggtgccggcccataagcccccggggcacagcctgatgttccaccttttgaacgactcacccaccctctctctctgcctcaacctactggaggagggcgcccgccagcttgacacatacgctcaattccctggcaagaagcagttagaatctgcagttctgcactgtctgtgtttgctggagctagccctgcagaaggaggtgacgttcatggatctgctgagagaaagtcaaacatcacttcttgtgtctcctttggagcagctcctgcagggcgtcagtgctcagagcagaaaggcagatcacatcaccaacattgctaggtacctgtatcacagcagctccaatcctgatgctgcgttccagagtgcaaagatcctgcgacgtatcactcgctacccaaacatccaggccagactggttggagacttcactcatgatcaggcagtgagtgagaggttgatggccggctttgtggagtgtctggacagtgaagaggctcaggaaggagtgaccacaaatgactcagactctgagaaacgggtggccagaattcgtcatgagaccaagatccacatcttgaatcttttgatcacgtccctggagctaacaggccccaatctgggcctgtatctgctgggctatgaagtcaagaagccagtttcctccactaaccttcaagacccaggtgttcttggctgtccgcggagctgcctgcatgcgattctcagtctgcttcagaggggcagtgactctcgctctggacctgggctcattaaacaggctcctcaactagctgaactctgctaccaggtgatttatcagctgtgcgcatgtcctgacacctctggcccaaccatgagatacctcaggaccagtcaggacttcctgttctctcatctgcaacacctacctttcgttttatcagaaaatgagatcgcggctctgtctcagatgtcctggctaatgaaaaccacagcaatcgagctccgagtgacctcactgaaccgccagcgctcacacacacagagactcctgaacctcctcctcgatgaccagccacacacattacacacagcagatggagagaccggcatggaggaggagaacagatcagtcagtggtttcctgcagtttggcaccgtctccaaggtgcgcaggaggctgctcagtgttttggatgccatagatttcagtcaggaggcaccagagcttttgcagctggacttctttgagcgcactcagatcgagcaggtcatcactaactgtgaacatgtcaacgagcagggacacaccgtctgcaatgtcaagttgctgcatcgagttttagttgcagagatcaatgcactacagggcatggcagccatcgggcaaagaccactgctaatggaggaggtgaattcagtcctgcagcaggtggtggaaaggaatcgcgtgcggcgcagtctcagtgccaagcgccatgctctgcagagctggaggagtctggtggagaccatcctcaccgcctgtccttcagaactcatccctgcagaccagcggcagctcatcatcagagatctgctgctcgacctgcatgacaaggtgttatcagaagatgctgctggtgaactgatgccaatcgtagccggagcagtcttcacattgacagcacacctcagccaatcagtgctgtccgaacagcagggggtggggccagagggtggctctggatcaggatttgcatccattgctaactccgcccttcacctcatcctgaggaagctgctggactttatcttgtgcacaggtggaggctttcagcgtctcagggctcatttgtatggagctctgctgtactacctgcagatcgcccagaaacctgaggagccagagacactgcagactggcacatccatgtgggagcgtttgactgcccctgaagattgcttctccaagctacagagagaaaacctgtccatcatcgagagctacggcactgcgctaatggaagtggtgtgcagagacgcttgtgatggccatgagatcggccgaatgctggctctggctgtgttagacagggtgttgtctatagacaggcagtgtcagtggctggtgtacttgtgtaacagtggttacctgcgtgtgctggtggagagtttaaagcaggatgacgtttctttgcaaactcttctcacgcctcagccgccgctgcttaaaccgttgtacatctacgagtccaaaatggctctgctgacccgcgtggccaagaccgctcagggtgcgatggagctgctgcgctgtggtctggtcgctcagctggtggagtgtcaggtgtttcacatgctccctcagaatgacgcactcagagtgtttgggcagagagatccttcagggtttattcctagtcctctggagcgatacaggcagatcctgcttcctacactcagactgatgcaggtcatcttgacctccaccaccgcacagcaccagcagggggcagcacaggtgctgcagtggcttatcgttcattcggatgtcattcagtctattctgcatggtcaggacatgagcatgggctctttacaggaactgtctctgctcactgccatcatcagcaagacggcactgccaggagcacttgagatgggacaggaaatcaacagcgctgccctcatggagttacagggacacatcggcagattccagcggcagtcgttgtctctgctggtgcgtctggtgggcactgatcgcgctcgctaccttaagcagattgaggacaccgtttctcccagcaacctagcagaaaaaagagaggaaatggaggttgccatgcaacagatctgtgctaatattatggagtactgccagacgctgctgctgcagagctcatctgaagcccagttctcactctgtctgttcagcccatcagcaagtgaaccagccgatgtgtccatcccctctgcccgcgtgcccagtctggggctggttctgctcctgctgaaaaacagcgccagcgacttcttcaggtatcacgacagtcacagacagagcctgaacaagctggagcgagtggagcagcttcctcctgaggaactcaaagagctgtgccagggtttggtgtctggttctggtggagtggaaaagatctcatcagtgcagagaaacgtactcgccaaacggagactcgtccagctggtcaacaacagagccaagcttcttgccctctgctcctatatcattgagacgtgtctgtttgtcatctggcgccacctagagttttacttgctttactgcactcccactgaccccaaagactcactgctgccaggttacagaggtcagctttctctcaagcttcaggattattttcaaatgctgttgaatgacatggtttcttaccagattgctctctgtgcagatcctgccggcagcagaggattgagcgtgtcgagagtgagccagcaagatcttgaacagttgcagagtgacatgtcgagcagcttcagtgagccgctgcagaggaagctgctggaggtggagggactttatagcaaaagccgctctcgtcacaccttcatccaggccctgacacgcaggatccgcggcctcgtacaccacgccaaaagctgaactccggcatgcagattttctctaattgtgagaaaagaaaaatcttttgaattcggtgtcttttttgcagttttgatgactatcaatccacacttgaggttttctgcctatgatagtcgctgtattggctttctgcgtttttctaatgtggtcattaaatgcttttctaacagaca

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